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Items: 1 to 50 of 56

1.

Regulation of Glucose Handling by the Skeleton: Insights From Mouse and Human Studies.

Liu JM, Rosen CJ, Ducy P, Kousteni S, Karsenty G.

Diabetes. 2016 Nov;65(11):3225-3232. Review. No abstract available.

2.

Serotonin-reuptake inhibitors act centrally to cause bone loss in mice by counteracting a local anti-resorptive effect.

Ortuño MJ, Robinson ST, Subramanyam P, Paone R, Huang YY, Guo XE, Colecraft HM, Mann JJ, Ducy P.

Nat Med. 2016 Oct;22(10):1170-1179. doi: 10.1038/nm.4166. Epub 2016 Sep 5.

3.

Lrp5 regulation of bone mass and serotonin synthesis in the gut.

Kode A, Obri A, Paone R, Kousteni S, Ducy P, Karsenty G.

Nat Med. 2014 Nov;20(11):1228-9. doi: 10.1038/nm.3698. No abstract available.

PMID:
25375916
4.

Osteocalcin promotes β-cell proliferation during development and adulthood through Gprc6a.

Wei J, Hanna T, Suda N, Karsenty G, Ducy P.

Diabetes. 2014 Mar;63(3):1021-31. doi: 10.2337/db13-0887. Epub 2013 Sep 5.

5.

How understanding gut serotonin secretion could potentially lead to new treatments for osteoporosis.

Ortuño MJ, Ducy P.

Expert Rev Endocrinol Metab. 2013 Mar;8(2):93-95. doi: 10.1586/eem.12.80. No abstract available.

PMID:
30736168
6.

Antidepressant medications and osteoporosis.

Rizzoli R, Cooper C, Reginster JY, Abrahamsen B, Adachi JD, Brandi ML, Bruyère O, Compston J, Ducy P, Ferrari S, Harvey NC, Kanis JA, Karsenty G, Laslop A, Rabenda V, Vestergaard P.

Bone. 2012 Sep;51(3):606-13. doi: 10.1016/j.bone.2012.05.018. Epub 2012 May 30. Review.

PMID:
22659406
7.

Efficacy of serotonin inhibition in mouse models of bone loss.

Inose H, Zhou B, Yadav VK, Guo XE, Karsenty G, Ducy P.

J Bone Miner Res. 2011 Sep;26(9):2002-11. doi: 10.1002/jbmr.439.

8.

Intermittent injections of osteocalcin improve glucose metabolism and prevent type 2 diabetes in mice.

Ferron M, McKee MD, Levine RL, Ducy P, Karsenty G.

Bone. 2012 Feb;50(2):568-75. doi: 10.1016/j.bone.2011.04.017. Epub 2011 Apr 29.

9.

The role of osteocalcin in the endocrine cross-talk between bone remodelling and energy metabolism.

Ducy P.

Diabetologia. 2011 Jun;54(6):1291-7. doi: 10.1007/s00125-011-2155-z. Epub 2011 Apr 19. Review.

PMID:
21503740
10.

Endocrine regulation of male fertility by the skeleton.

Oury F, Sumara G, Sumara O, Ferron M, Chang H, Smith CE, Hermo L, Suarez S, Roth BL, Ducy P, Karsenty G.

Cell. 2011 Mar 4;144(5):796-809. doi: 10.1016/j.cell.2011.02.004. Epub 2011 Feb 17.

11.

5-HT and bone biology.

Ducy P.

Curr Opin Pharmacol. 2011 Feb;11(1):34-8. doi: 10.1016/j.coph.2011.01.007. Epub 2011 Feb 12. Review.

PMID:
21320797
12.

The two faces of serotonin in bone biology.

Ducy P, Karsenty G.

J Cell Biol. 2010 Oct 4;191(1):7-13. doi: 10.1083/jcb.201006123. Review.

13.

Fibrillin-1 and -2 differentially modulate endogenous TGF-β and BMP bioavailability during bone formation.

Nistala H, Lee-Arteaga S, Smaldone S, Siciliano G, Carta L, Ono RN, Sengle G, Arteaga-Solis E, Levasseur R, Ducy P, Sakai LY, Karsenty G, Ramirez F.

J Cell Biol. 2010 Sep 20;190(6):1107-21. doi: 10.1083/jcb.201003089.

14.

Insulin signaling in osteoblasts integrates bone remodeling and energy metabolism.

Ferron M, Wei J, Yoshizawa T, Del Fattore A, DePinho RA, Teti A, Ducy P, Karsenty G.

Cell. 2010 Jul 23;142(2):296-308. doi: 10.1016/j.cell.2010.06.003.

15.

An ELISA-based method to quantify osteocalcin carboxylation in mice.

Ferron M, Wei J, Yoshizawa T, Ducy P, Karsenty G.

Biochem Biophys Res Commun. 2010 Jul 9;397(4):691-6. doi: 10.1016/j.bbrc.2010.06.008. Epub 2010 Jun 4.

16.

Co-dependence of bone and energy metabolisms.

Wei J, Ducy P.

Arch Biochem Biophys. 2010 Nov 1;503(1):35-40. doi: 10.1016/j.abb.2010.05.021. Epub 2010 May 31. Review.

17.

Lrp5 and bone formation : A serotonin-dependent pathway.

Yadav VK, Ducy P.

Ann N Y Acad Sci. 2010 Mar;1192:103-9. doi: 10.1111/j.1749-6632.2009.05312.x. Review.

PMID:
20392224
18.

Genetic analysis of Lrp5 function in osteoblast progenitors.

Yadav VK, Arantes HP, Barros ER, Lazaretti-Castro M, Ducy P.

Calcif Tissue Int. 2010 May;86(5):382-8. doi: 10.1007/s00223-010-9350-7. Epub 2010 Mar 24.

PMID:
20333369
19.

Pharmacological inhibition of gut-derived serotonin synthesis is a potential bone anabolic treatment for osteoporosis.

Yadav VK, Balaji S, Suresh PS, Liu XS, Lu X, Li Z, Guo XE, Mann JJ, Balapure AK, Gershon MD, Medhamurthy R, Vidal M, Karsenty G, Ducy P.

Nat Med. 2010 Mar;16(3):308-12. doi: 10.1038/nm.2098. Epub 2010 Feb 7.

20.

Lrp5 controls bone formation by inhibiting serotonin synthesis in the duodenum.

Yadav VK, Ryu JH, Suda N, Tanaka KF, Gingrich JA, Schütz G, Glorieux FH, Chiang CY, Zajac JD, Insogna KL, Mann JJ, Hen R, Ducy P, Karsenty G.

Cell. 2008 Nov 28;135(5):825-37. doi: 10.1016/j.cell.2008.09.059.

21.

Dickkopf-like1 regulates postpubertal spermatocyte apoptosis and testosterone production.

Dakhova O, O'Day D, Kinet N, Yucer N, Wiese M, Shetty G, Ducy P.

Endocrinology. 2009 Jan;150(1):404-12. doi: 10.1210/en.2008-0673. Epub 2008 Sep 25.

PMID:
18818293
22.

Osteocalcin differentially regulates beta cell and adipocyte gene expression and affects the development of metabolic diseases in wild-type mice.

Ferron M, Hinoi E, Karsenty G, Ducy P.

Proc Natl Acad Sci U S A. 2008 Apr 1;105(13):5266-70. doi: 10.1073/pnas.0711119105. Epub 2008 Mar 24.

23.

Endocrine regulation of energy metabolism by the skeleton.

Lee NK, Sowa H, Hinoi E, Ferron M, Ahn JD, Confavreux C, Dacquin R, Mee PJ, McKee MD, Jung DY, Zhang Z, Kim JK, Mauvais-Jarvis F, Ducy P, Karsenty G.

Cell. 2007 Aug 10;130(3):456-69.

24.

Microarray analysis on Runx2-deficient mouse embryos reveals novel Runx2 functions and target genes during intramembranous and endochondral bone formation.

Vaes BL, Ducy P, Sijbers AM, Hendriks JM, van Someren EP, de Jong NG, van den Heuvel ER, Olijve W, van Zoelen EJ, Dechering KJ.

Bone. 2006 Oct;39(4):724-38. Epub 2006 Jun 13.

PMID:
16774856
25.

The hypothalamic control of bone mass, implication for the treatment of osteoporosis.

Karsenty G, Ducy P.

Ann Endocrinol (Paris). 2006 Apr;67(2):123. No abstract available.

PMID:
16639361
26.

A novel role for GADD45beta as a mediator of MMP-13 gene expression during chondrocyte terminal differentiation.

Ijiri K, Zerbini LF, Peng H, Correa RG, Lu B, Walsh N, Zhao Y, Taniguchi N, Huang XL, Otu H, Wang H, Wang JF, Komiya S, Ducy P, Rahman MU, Flavell RA, Gravallese EM, Oettgen P, Libermann TA, Goldring MB.

J Biol Chem. 2005 Nov 18;280(46):38544-55. Epub 2005 Sep 2.

27.

[Control of body mass by leptin occurs through the sympathetic nervous system].

Elefteriou F, Ducy P.

Med Sci (Paris). 2003 Apr;19(4):391-3. French. No abstract available.

28.

Parathyroid hormone bone anabolic action requires Cbfa1/Runx2-dependent signaling.

Krishnan V, Moore TL, Ma YL, Helvering LM, Frolik CA, Valasek KM, Ducy P, Geiser AG.

Mol Endocrinol. 2003 Mar;17(3):423-35. Epub 2002 Dec 18.

PMID:
12554794
29.

Leptin regulates bone formation via the sympathetic nervous system.

Takeda S, Elefteriou F, Levasseur R, Liu X, Zhao L, Parker KL, Armstrong D, Ducy P, Karsenty G.

Cell. 2002 Nov 1;111(3):305-17.

30.

Characterization of an osteoblast-specific enhancer element in the CBFA1 gene.

Zambotti A, Makhluf H, Shen J, Ducy P.

J Biol Chem. 2002 Nov 1;277(44):41497-506. Epub 2002 Aug 16.

31.

Molecular signaling: breakout session summary.

Damsky C, Heidaran M, Bottaro D, Crossin K, Ducy P, Ingber D.

Ann N Y Acad Sci. 2002 Jun;961:164-7. No abstract available.

PMID:
12081891
32.

Molecular signaling.

Ducy P.

Ann N Y Acad Sci. 2002 Jun;961:161. Review. No abstract available.

PMID:
12081889
33.

Central control of bone mass: brainstorming of the skeleton.

Amling M, Pogoda P, Beil FT, Schilling AF, Holzmann T, Priemel M, Blicharski D, Català-Lehnen P, Rueger JM, Ducy P, Karsenty G.

Adv Exp Med Biol. 2001;496:85-94. Review. No abstract available.

PMID:
11783628
34.
36.

Cbfa1: a molecular switch in osteoblast biology.

Ducy P.

Dev Dyn. 2000 Dec;219(4):461-71. Review.

37.

The osteoblast: a sophisticated fibroblast under central surveillance.

Ducy P, Schinke T, Karsenty G.

Science. 2000 Sep 1;289(5484):1501-4. Review.

PMID:
10968779
38.

The family of bone morphogenetic proteins.

Ducy P, Karsenty G.

Kidney Int. 2000 Jun;57(6):2207-14. Review.

39.

Leptin inhibits bone formation through a hypothalamic relay: a central control of bone mass.

Ducy P, Amling M, Takeda S, Priemel M, Schilling AF, Beil FT, Shen J, Vinson C, Rueger JM, Karsenty G.

Cell. 2000 Jan 21;100(2):197-207.

40.

Cbfa1 as a regulator of osteoblast differentiation and function.

Karsenty G, Ducy P, Starbuck M, Priemel M, Shen J, Geoffroy V, Amling M.

Bone. 1999 Jul;25(1):107-8. No abstract available.

PMID:
10423032
41.

A Cbfa1-dependent genetic pathway controls bone formation beyond embryonic development.

Ducy P, Starbuck M, Priemel M, Shen J, Pinero G, Geoffroy V, Amling M, Karsenty G.

Genes Dev. 1999 Apr 15;13(8):1025-36.

42.

Genetic control of cell differentiation in the skeleton.

Ducy P, Karsenty G.

Curr Opin Cell Biol. 1998 Oct;10(5):614-9. Review.

PMID:
9818172
43.

Dissociation between bone resorption and bone formation in osteopenic transgenic mice.

Corral DA, Amling M, Priemel M, Loyer E, Fuchs S, Ducy P, Baron R, Karsenty G.

Proc Natl Acad Sci U S A. 1998 Nov 10;95(23):13835-40.

44.

Functional hierarchy between two OSE2 elements in the control of osteocalcin gene expression in vivo.

Frendo JL, Xiao G, Fuchs S, Franceschi RT, Karsenty G, Ducy P.

J Biol Chem. 1998 Nov 13;273(46):30509-16.

45.
47.

Missense mutations abolishing DNA binding of the osteoblast-specific transcription factor OSF2/CBFA1 in cleidocranial dysplasia.

Lee B, Thirunavukkarasu K, Zhou L, Pastore L, Baldini A, Hecht J, Geoffroy V, Ducy P, Karsenty G.

Nat Genet. 1997 Jul;16(3):307-10.

PMID:
9207800
48.

Osf2/Cbfa1: a transcriptional activator of osteoblast differentiation.

Ducy P, Zhang R, Geoffroy V, Ridall AL, Karsenty G.

Cell. 1997 May 30;89(5):747-54.

49.

Spontaneous calcification of arteries and cartilage in mice lacking matrix GLA protein.

Luo G, Ducy P, McKee MD, Pinero GJ, Loyer E, Behringer RR, Karsenty G.

Nature. 1997 Mar 6;386(6620):78-81.

PMID:
9052783
50.

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