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Items: 1 to 50 of 170

1.

Genomic and non-genomic regulation of PGC1 isoforms by estrogen to increase cerebral vascular mitochondrial biogenesis and reactive oxygen species protection.

Kemper MF, Stirone C, Krause DN, Duckles SP, Procaccio V.

Eur J Pharmacol. 2014 Jan 15;723:322-9. doi: 10.1016/j.ejphar.2013.11.009. Epub 2013 Nov 22.

2.

Endogenous ovarian hormones affect mitochondrial efficiency in cerebral endothelium via distinct regulation of PGC-1 isoforms.

Kemper MF, Zhao Y, Duckles SP, Krause DN.

J Cereb Blood Flow Metab. 2013 Jan;33(1):122-8. doi: 10.1038/jcbfm.2012.159. Epub 2012 Oct 24.

3.

17β-Estradiol prevents cell death and mitochondrial dysfunction by an estrogen receptor-dependent mechanism in astrocytes after oxygen-glucose deprivation/reperfusion.

Guo J, Duckles SP, Weiss JH, Li X, Krause DN.

Free Radic Biol Med. 2012 Jun 1-15;52(11-12):2151-60. doi: 10.1016/j.freeradbiomed.2012.03.005. Epub 2012 Apr 19.

4.

Local oestrogenic/androgenic balance in the cerebral vasculature.

Krause DN, Duckles SP, Gonzales RJ.

Acta Physiol (Oxf). 2011 Sep;203(1):181-6. doi: 10.1111/j.1748-1716.2011.02323.x. Epub 2011 May 27. Review.

5.

[Mechanism of estrogen-mediated neuroprotection: regulation of mitochondrial function].

Guo JB, Tie L, Krause DN, Duckles SP, Li XJ.

Sheng Li Ke Xue Jin Zhan. 2010 Jun;41(3):165-70. Review. Chinese.

PMID:
21416974
6.

Mechanisms of cerebrovascular protection: oestrogen, inflammation and mitochondria.

Duckles SP, Krause DN.

Acta Physiol (Oxf). 2011 Sep;203(1):149-54. doi: 10.1111/j.1748-1716.2010.02184.x. Epub 2010 Oct 11. Review.

7.

Hormonal modulation of endothelial NO production.

Duckles SP, Miller VM.

Pflugers Arch. 2010 May;459(6):841-51. doi: 10.1007/s00424-010-0797-1. Epub 2010 Mar 7. Review.

8.

Estrogen-receptor-mediated protection of cerebral endothelial cell viability and mitochondrial function after ischemic insult in vitro.

Guo J, Krause DN, Horne J, Weiss JH, Li X, Duckles SP.

J Cereb Blood Flow Metab. 2010 Mar;30(3):545-54. doi: 10.1038/jcbfm.2009.226. Epub 2009 Oct 28.

9.

Dihydrotestosterone stimulates cerebrovascular inflammation through NFkappaB, modulating contractile function.

Gonzales RJ, Duckles SP, Krause DN.

J Cereb Blood Flow Metab. 2009 Feb;29(2):244-53. doi: 10.1038/jcbfm.2008.115. Epub 2008 Oct 22.

10.

Vascular actions of estrogens: functional implications.

Miller VM, Duckles SP.

Pharmacol Rev. 2008 Jun;60(2):210-41. doi: 10.1124/pr.107.08002. Epub 2008 Jun 25. Review.

11.

Mitochondrial effects of estrogen are mediated by estrogen receptor alpha in brain endothelial cells.

Razmara A, Sunday L, Stirone C, Wang XB, Krause DN, Duckles SP, Procaccio V.

J Pharmacol Exp Ther. 2008 Jun;325(3):782-90. doi: 10.1124/jpet.107.134072. Epub 2008 Mar 19.

12.

Estrogen suppresses brain mitochondrial oxidative stress in female and male rats.

Razmara A, Duckles SP, Krause DN, Procaccio V.

Brain Res. 2007 Oct 24;1176:71-81. Epub 2007 Aug 24.

13.

A career in pharmacology. In search of beauty and joy.

Duckles SP.

Mol Interv. 2007 Aug;7(4):183-9. No abstract available.

PMID:
17827436
14.

Cerebrovascular effects of oestrogen: multiplicity of action.

Duckles SP, Krause DN.

Clin Exp Pharmacol Physiol. 2007 Aug;34(8):801-8. Review.

PMID:
17600562
15.

Androgenic/estrogenic balance in the male rat cerebral circulation: metabolic enzymes and sex steroid receptors.

Gonzales RJ, Ansar S, Duckles SP, Krause DN.

J Cereb Blood Flow Metab. 2007 Nov;27(11):1841-52. Epub 2007 Apr 4.

16.

Age alters cerebrovascular inflammation and effects of estrogen.

Sunday L, Osuna C, Krause DN, Duckles SP.

Am J Physiol Heart Circ Physiol. 2007 May;292(5):H2333-40. Epub 2007 Jan 5.

17.

Influence of sex steroid hormones on cerebrovascular function.

Krause DN, Duckles SP, Pelligrino DA.

J Appl Physiol (1985). 2006 Oct;101(4):1252-61. Epub 2006 Jun 22. Review.

18.

Estrogen and mitochondria: a new paradigm for vascular protection?

Duckles SP, Krause DN, Stirone C, Procaccio V.

Mol Interv. 2006 Feb;6(1):26-35. Review.

PMID:
16507748
19.

Estrogen and progestagens differentially modulate vascular proinflammatory factors.

Sunday L, Tran MM, Krause DN, Duckles SP.

Am J Physiol Endocrinol Metab. 2006 Aug;291(2):E261-7. Epub 2006 Feb 21.

20.

Testosterone augments endotoxin-mediated cerebrovascular inflammation in male rats.

Razmara A, Krause DN, Duckles SP.

Am J Physiol Heart Circ Physiol. 2005 Nov;289(5):H1843-50. Epub 2005 Jul 8.

21.

Estrogen increases mitochondrial efficiency and reduces oxidative stress in cerebral blood vessels.

Stirone C, Duckles SP, Krause DN, Procaccio V.

Mol Pharmacol. 2005 Oct;68(4):959-65. Epub 2005 Jun 30.

PMID:
15994367
22.

Testosterone treatment increases thromboxane function in rat cerebral arteries.

Gonzales RJ, Ghaffari AA, Duckles SP, Krause DN.

Am J Physiol Heart Circ Physiol. 2005 Aug;289(2):H578-85. Epub 2005 Mar 11. Erratum in: Am J Physiol Heart Circ Physiol. 2005 Dec;289(6):H2754.

23.

Estrogen receptor activation of phosphoinositide-3 kinase, akt, and nitric oxide signaling in cerebral blood vessels: rapid and long-term effects.

Stirone C, Boroujerdi A, Duckles SP, Krause DN.

Mol Pharmacol. 2005 Jan;67(1):105-13. Epub 2004 Oct 20.

PMID:
15496504
24.

Effect of estrogen on cerebrovascular prostaglandins is amplified in mice with dysfunctional NOS.

Li X, Geary GG, Gonzales RJ, Krause DN, Duckles SP.

Am J Physiol Heart Circ Physiol. 2004 Aug;287(2):H588-94.

25.

NO enhances noradrenaline release: modulation and mechanism.

Duckles SP, Mbaku E, Bucholz JN.

Auton Autacoid Pharmacol. 2003 Aug;23(4):237-8. No abstract available.

PMID:
15132134
26.

Estrogen suppresses IL-1beta-mediated induction of COX-2 pathway in rat cerebral blood vessels.

Ospina JA, Brevig HN, Krause DN, Duckles SP.

Am J Physiol Heart Circ Physiol. 2004 May;286(5):H2010-9. Epub 2003 Dec 18.

27.
28.

Testosterone suppresses endothelium-dependent dilation of rat middle cerebral arteries.

Gonzales RJ, Krause DN, Duckles SP.

Am J Physiol Heart Circ Physiol. 2004 Feb;286(2):H552-60. Epub 2003 Oct 9.

29.

17beta-estradiol decreases vascular tone in cerebral arteries by shifting COX-dependent vasoconstriction to vasodilation.

Ospina JA, Duckles SP, Krause DN.

Am J Physiol Heart Circ Physiol. 2003 Jul;285(1):H241-50. Epub 2003 Mar 13.

30.

Vascular neuroeffector mechanisms: the next 30 years.

Krause DN, Purdy RE, Pearce WJ, Duckles SP.

Trends Pharmacol Sci. 2002 Dec;23(12):541-2.

PMID:
12457765
31.

Chronic hypoxia alters the function of NOS nerves in cerebral arteries of near-term fetal and adult sheep.

Mbaku EM, Zhang L, Pearce WJ, Duckles SP, Buchholz J.

J Appl Physiol (1985). 2003 Feb;94(2):724-32. Epub 2002 Oct 25.

32.

Regional differences in the effect of oestrogen on vascular tone in isolated rabbit arteries.

Saetrum Opgaard O, Duckles SP, Krause DN.

Pharmacol Toxicol. 2002 Aug;91(2):77-82.

PMID:
12420796
33.

Multiple forms of estrogen receptor-alpha in cerebral blood vessels: regulation by estrogen.

Stirone C, Duckles SP, Krause DN.

Am J Physiol Endocrinol Metab. 2003 Jan;284(1):E184-92. Epub 2002 Sep 11.

34.

MT(2) melatonin receptors are present and functional in rat caudal artery.

Masana MI, Doolen S, Ersahin C, Al-Ghoul WM, Duckles SP, Dubocovich ML, Krause DN.

J Pharmacol Exp Ther. 2002 Sep;302(3):1295-302.

PMID:
12183692
35.

Male-female differences in the relative contribution of endothelial vasodilators released by rat tail artery.

Pak KJ, Geary GG, Duckles SP, Krause DN.

Life Sci. 2002 Aug 23;71(14):1633-42.

PMID:
12137910
37.

Aging and calcium buffering in adrenergic neurons.

Pottorf WJ, Duckles SP, Buchholz JN.

Auton Neurosci. 2002 Feb 28;96(1):2-7. Review.

PMID:
11911497
38.
39.

Selected contribution: cerebrovascular nos and cyclooxygenase are unaffected by estrogen in mice lacking estrogen receptor-alpha.

Geary GG, McNeill AM, Ospina JA, Krause DN, Korach KS, Duckles SP.

J Appl Physiol (1985). 2001 Nov;91(5):2391-9; discussion 2389-90.

40.

Chronic hypoxia alters prejunctional alpha(2)-receptor function in vascular adrenergic nerves of adult and fetal sheep.

Buchholz J, Duckles SP.

Am J Physiol Regul Integr Comp Physiol. 2001 Sep;281(3):R926-34.

41.

SERCA function declines with age in adrenergic nerves from the superior cervical ganglion.

Pottorf WJ, Duckles SP, Buchholz JN.

J Auton Pharmacol. 2000 Oct-Dec;20(5-6):281-90.

PMID:
11350493
42.

Mechanisms of calcium buffering in adrenergic neurones and effects of ageing: testing the limits of homeostasis.

Pottorf WJ, Duckles SP, Buchholz JN.

J Auton Pharmacol. 2000 Apr;20(2):63-75. Review. No abstract available.

PMID:
11095545
43.

Adrenergic nerves compensate for a decline in calcium buffering during ageing.

Pottorf WJ, Duckles SP, Buchholz JN.

J Auton Pharmacol. 2000 Feb;20(1):1-13.

PMID:
11048956
44.

Gonadal hormones affect diameter of male rat cerebral arteries through endothelium-dependent mechanisms.

Geary GG, Krause DN, Duckles SP.

Am J Physiol Heart Circ Physiol. 2000 Aug;279(2):H610-8.

45.

Estrogen reduces mouse cerebral artery tone through endothelial NOS- and cyclooxygenase-dependent mechanisms.

Geary GG, Krause DN, Duckles SP.

Am J Physiol Heart Circ Physiol. 2000 Aug;279(2):H511-9.

46.

Melatonin and cardiovascular function.

Krause DN, Geary GG, Doolen S, Duckles SP.

Adv Exp Med Biol. 1999;460:299-310. Review. No abstract available.

PMID:
10810525
47.

Progesterone exacerbates striatal stroke injury in progesterone-deficient female animals.

Murphy SJ, Traystman RJ, Hurn PD, Duckles SP.

Stroke. 2000 May;31(5):1173-8.

PMID:
10797182
48.

Nitric-oxide synthase-containing nerves facilitate adrenergic transmitter release in sheep middle cerebral arteries.

Mbaku EN, Zhang L, Duckles SP, Buchholz J.

J Pharmacol Exp Ther. 2000 May;293(2):397-402.

PMID:
10773008
49.

Identification of the natural ligand of an orphan G-protein-coupled receptor involved in the regulation of vasoconstriction.

Nothacker HP, Wang Z, McNeill AM, Saito Y, Merten S, O'Dowd B, Duckles SP, Civelli O.

Nat Cell Biol. 1999 Oct;1(6):383-5. No abstract available.

PMID:
10559967
50.

Effects of maturation on adrenergic neurotransmission in ovine cerebral arteries.

Pearce WJ, Duckles SP, Buchholz J.

Am J Physiol. 1999 Oct;277(4):R931-7. doi: 10.1152/ajpregu.1999.277.4.R931.

PMID:
10516229

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