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Items: 1 to 50 of 87

1.

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018.

Galluzzi L, Vitale I, Aaronson SA, Abrams JM, Adam D, Agostinis P, Alnemri ES, Altucci L, Amelio I, Andrews DW, Annicchiarico-Petruzzelli M, Antonov AV, Arama E, Baehrecke EH, Barlev NA, Bazan NG, Bernassola F, Bertrand MJM, Bianchi K, Blagosklonny MV, Blomgren K, Borner C, Boya P, Brenner C, Campanella M, Candi E, Carmona-Gutierrez D, Cecconi F, Chan FK, Chandel NS, Cheng EH, Chipuk JE, Cidlowski JA, Ciechanover A, Cohen GM, Conrad M, Cubillos-Ruiz JR, Czabotar PE, D'Angiolella V, Dawson TM, Dawson VL, De Laurenzi V, De Maria R, Debatin KM, DeBerardinis RJ, Deshmukh M, Di Daniele N, Di Virgilio F, Dixit VM, Dixon SJ, Duckett CS, Dynlacht BD, El-Deiry WS, Elrod JW, Fimia GM, Fulda S, García-Sáez AJ, Garg AD, Garrido C, Gavathiotis E, Golstein P, Gottlieb E, Green DR, Greene LA, Gronemeyer H, Gross A, Hajnoczky G, Hardwick JM, Harris IS, Hengartner MO, Hetz C, Ichijo H, Jäättelä M, Joseph B, Jost PJ, Juin PP, Kaiser WJ, Karin M, Kaufmann T, Kepp O, Kimchi A, Kitsis RN, Klionsky DJ, Knight RA, Kumar S, Lee SW, Lemasters JJ, Levine B, Linkermann A, Lipton SA, Lockshin RA, López-Otín C, Lowe SW, Luedde T, Lugli E, MacFarlane M, Madeo F, Malewicz M, Malorni W, Manic G, Marine JC, Martin SJ, Martinou JC, Medema JP, Mehlen P, Meier P, Melino S, Miao EA, Molkentin JD, Moll UM, Muñoz-Pinedo C, Nagata S, Nuñez G, Oberst A, Oren M, Overholtzer M, Pagano M, Panaretakis T, Pasparakis M, Penninger JM, Pereira DM, Pervaiz S, Peter ME, Piacentini M, Pinton P, Prehn JHM, Puthalakath H, Rabinovich GA, Rehm M, Rizzuto R, Rodrigues CMP, Rubinsztein DC, Rudel T, Ryan KM, Sayan E, Scorrano L, Shao F, Shi Y, Silke J, Simon HU, Sistigu A, Stockwell BR, Strasser A, Szabadkai G, Tait SWG, Tang D, Tavernarakis N, Thorburn A, Tsujimoto Y, Turk B, Vanden Berghe T, Vandenabeele P, Vander Heiden MG, Villunger A, Virgin HW, Vousden KH, Vucic D, Wagner EF, Walczak H, Wallach D, Wang Y, Wells JA, Wood W, Yuan J, Zakeri Z, Zhivotovsky B, Zitvogel L, Melino G, Kroemer G.

Cell Death Differ. 2018 Mar;25(3):486-541. doi: 10.1038/s41418-017-0012-4. Epub 2018 Jan 23. Review.

2.

IAPs protect host target tissues from graft-versus-host disease in mice.

Toubai T, Rossi C, Oravecz-Wilson K, Liu C, Zajac C, Wu SJ, Sun Y, Fujiwara H, Tamaki H, Peltier D, Riwes M, Henig I, Brabbs S, Duckett CS, Wang S, Reddy P.

Blood Adv. 2017 Aug 16;1(19):1517-1532. doi: 10.1182/bloodadvances.2017004242. eCollection 2017 Aug 22.

3.

Heat Shock Protein 70 (Hsp70) Suppresses RIP1-Dependent Apoptotic and Necroptotic Cascades.

Srinivasan SR, Cesa LC, Li X, Julien O, Zhuang M, Shao H, Chung J, Maillard I, Wells JA, Duckett CS, Gestwicki JE.

Mol Cancer Res. 2018 Jan;16(1):58-68. doi: 10.1158/1541-7786.MCR-17-0408. Epub 2017 Sep 28.

4.

Inhibitor of apoptosis proteins as intracellular signaling intermediates.

Kocab AJ, Duckett CS.

FEBS J. 2016 Jan;283(2):221-31. doi: 10.1111/febs.13554. Epub 2015 Nov 4. Review.

5.

Targeting Inhibitor of Apoptosis Proteins Protects from Bleomycin-Induced Lung Fibrosis.

Ashley SL, Sisson TH, Wheaton AK, Kim KK, Wilke CA, Ajayi IO, Subbotina N, Wang S, Duckett CS, Moore BB, Horowitz JC.

Am J Respir Cell Mol Biol. 2016 Apr;54(4):482-92. doi: 10.1165/rcmb.2015-0148OC.

6.

Effects of physiological and synthetic IAP antagonism on c-IAP-dependent signaling.

Kocab AJ, Veloso A, Paulsen MT, Ljungman M, Duckett CS.

Oncogene. 2015 Oct;34(43):5472-81. doi: 10.1038/onc.2015.3. Epub 2015 Feb 9.

7.

Copper is a potent inhibitor of both the canonical and non-canonical NFκB pathways.

Kenneth NS, Hucks GE Jr, Kocab AJ, McCollom AL, Duckett CS.

Cell Cycle. 2014;13(6):1006-14. doi: 10.4161/cc.27922. Epub 2014 Feb 3.

8.

Distinctive effects of the cellular inhibitor of apoptosis protein c-IAP2 through stabilization by XIAP in glioblastoma multiforme cells.

Yang W, Cooke M, Duckett CS, Yang X, Dorsey JF.

Cell Cycle. 2014;13(6):992-1005. doi: 10.4161/cc.27880. Epub 2014 Jan 22.

9.

IAP proteins: regulators of cell migration and development.

Kenneth NS, Duckett CS.

Curr Opin Cell Biol. 2012 Dec;24(6):871-5. doi: 10.1016/j.ceb.2012.11.004. Epub 2012 Dec 5. Review.

PMID:
23219152
10.

An inactivating caspase 11 passenger mutation originating from the 129 murine strain in mice targeted for c-IAP1.

Kenneth NS, Younger JM, Hughes ED, Marcotte D, Barker PA, Saunders TL, Duckett CS.

Biochem J. 2012 Apr 15;443(2):355-9. doi: 10.1042/BJ20120249.

11.
12.

Regulation of the copper chaperone CCS by XIAP-mediated ubiquitination.

Brady GF, Galbán S, Liu X, Basrur V, Gitlin JD, Elenitoba-Johnson KS, Wilson TE, Duckett CS.

Mol Cell Biol. 2010 Apr;30(8):1923-36. doi: 10.1128/MCB.00900-09. Epub 2010 Feb 12.

13.

Phenotypic differences between mice deficient in XIAP and SAP, two factors targeted in X-linked lymphoproliferative syndrome (XLP).

Rumble JM, Oetjen KA, Stein PL, Schwartzberg PL, Moore BB, Duckett CS.

Cell Immunol. 2009;259(1):82-9. doi: 10.1016/j.cellimm.2009.05.017. Epub 2009 Jun 13.

14.

XIAP as a ubiquitin ligase in cellular signaling.

Galbán S, Duckett CS.

Cell Death Differ. 2010 Jan;17(1):54-60. doi: 10.1038/cdd.2009.81. Review.

15.

Enhanced cytoprotective effects of the inhibitor of apoptosis protein cellular IAP1 through stabilization with TRAF2.

Csomos RA, Brady GF, Duckett CS.

J Biol Chem. 2009 Jul 31;284(31):20531-9. doi: 10.1074/jbc.M109.029983. Epub 2009 Jun 8.

16.

The E3 ubiquitin ligase cIAP1 binds and ubiquitinates caspase-3 and -7 via unique mechanisms at distinct steps in their processing.

Choi YE, Butterworth M, Malladi S, Duckett CS, Cohen GM, Bratton SB.

J Biol Chem. 2009 May 8;284(19):12772-82. doi: 10.1074/jbc.M807550200. Epub 2009 Mar 3.

17.

Two distinct signalling cascades target the NF-kappaB regulatory factor c-IAP1 for degradation.

Csomos RA, Wright CW, Galbán S, Oetjen KA, Duckett CS.

Biochem J. 2009 Apr 28;420(1):83-91. doi: 10.1042/BJ20082140.

18.

A caspase homolog keeps CED-3 in check.

Brady GF, Duckett CS.

Trends Biochem Sci. 2009 Mar;34(3):104-7. doi: 10.1016/j.tibs.2008.11.003. Epub 2009 Jan 23.

19.

The aryl hydrocarbon nuclear translocator alters CD30-mediated NF-kappaB-dependent transcription.

Wright CW, Duckett CS.

Science. 2009 Jan 9;323(5911):251-5. doi: 10.1126/science.1162818.

20.

Caspases and IAPs: a dance of death ensures cell survival.

Galbán S, Brady GF, Duckett CS.

Mol Cell. 2008 Nov 21;32(4):462-3. doi: 10.1016/j.molcel.2008.11.005.

21.

Diverse functions within the IAP family.

Rumble JM, Duckett CS.

J Cell Sci. 2008 Nov 1;121(Pt 21):3505-7. doi: 10.1242/jcs.040303. No abstract available.

22.

Inhibitor of apoptosis proteins in eukaryotic evolution and development: a model of thematic conservation.

O'Riordan MX, Bauler LD, Scott FL, Duckett CS.

Dev Cell. 2008 Oct;15(4):497-508. doi: 10.1016/j.devcel.2008.09.012. Review.

23.

Cytoprotective effects of IAPs revealed by a small molecule antagonist.

Galbán S, Hwang C, Rumble JM, Oetjen KA, Wright CW, Boudreault A, Durkin J, Gillard JW, Jaquith JB, Morris SJ, Duckett CS.

Biochem J. 2009 Feb 1;417(3):765-71. doi: 10.1042/BJ20081677.

24.

XIAP regulates cytosol-specific innate immunity to Listeria infection.

Bauler LD, Duckett CS, O'Riordan MX.

PLoS Pathog. 2008 Aug 29;4(8):e1000142. doi: 10.1371/journal.ppat.1000142.

25.

Apoptotic sensitivity of murine IAP-deficient cells.

Rumble JM, Bertrand MJ, Csomos RA, Wright CW, Albert L, Mak TW, Barker PA, Duckett CS.

Biochem J. 2008 Oct 1;415(1):21-5. doi: 10.1042/BJ20081188.

26.

X-linked inhibitor of apoptosis deficiency in the TRAMP mouse prostate cancer model.

Hwang C, Oetjen KA, Kosoff D, Wojno KJ, Albertelli MA, Dunn RL, Robins DM, Cooney KA, Duckett CS.

Cell Death Differ. 2008 May;15(5):831-40. doi: 10.1038/cdd.2008.15. Epub 2008 Feb 8.

27.

New insights into the function of IAP proteins: modulation of the MYC/MAX/MAD network.

Wright CW, Duckett CS.

Dev Cell. 2008 Jan;14(1):3-4. doi: 10.1016/j.devcel.2007.12.015.

28.

Apoptosis-inducing factor is a target for ubiquitination through interaction with XIAP.

Wilkinson JC, Wilkinson AS, Galbán S, Csomos RA, Duckett CS.

Mol Cell Biol. 2008 Jan;28(1):237-47. Epub 2007 Oct 29.

29.

The iap genes: unique arbitrators of cell death.

Clem RJ, Duckett CS.

Trends Cell Biol. 1997 Sep;7(9):337-9.

PMID:
17708972
30.

EZH2 regulates the transcription of estrogen-responsive genes through association with REA, an estrogen receptor corepressor.

Hwang C, Giri VN, Wilkinson JC, Wright CW, Wilkinson AS, Cooney KA, Duckett CS.

Breast Cancer Res Treat. 2008 Jan;107(2):235-42. Epub 2007 Apr 24.

PMID:
17453341
31.

XIAP: cell death regulation meets copper homeostasis.

Mufti AR, Burstein E, Duckett CS.

Arch Biochem Biophys. 2007 Jul 15;463(2):168-74. Epub 2007 Feb 22. Review.

32.

CD30 activates both the canonical and alternative NF-kappaB pathways in anaplastic large cell lymphoma cells.

Wright CW, Rumble JM, Duckett CS.

J Biol Chem. 2007 Apr 6;282(14):10252-62. Epub 2007 Jan 29.

33.

Characterization of COMMD protein-protein interactions in NF-kappaB signalling.

de Bie P, van de Sluis B, Burstein E, Duran KJ, Berger R, Duckett CS, Wijmenga C, Klomp LW.

Biochem J. 2006 Aug 15;398(1):63-71.

34.

XIAP Is a copper binding protein deregulated in Wilson's disease and other copper toxicosis disorders.

Mufti AR, Burstein E, Csomos RA, Graf PC, Wilkinson JC, Dick RD, Challa M, Son JK, Bratton SB, Su GL, Brewer GJ, Jakob U, Duckett CS.

Mol Cell. 2006 Mar 17;21(6):775-85.

35.

Xaf1 can cooperate with TNFalpha in the induction of apoptosis, independently of interaction with XIAP.

Xia Y, Novak R, Lewis J, Duckett CS, Phillips AC.

Mol Cell Biochem. 2006 Jun;286(1-2):67-76. Epub 2006 Jan 24.

36.
37.
38.

COMMD proteins, a novel family of structural and functional homologs of MURR1.

Burstein E, Hoberg JE, Wilkinson AS, Rumble JM, Csomos RA, Komarck CM, Maine GN, Wilkinson JC, Mayo MW, Duckett CS.

J Biol Chem. 2005 Jun 10;280(23):22222-32. Epub 2005 Mar 30.

39.

Differential role for TLR3 in respiratory syncytial virus-induced chemokine expression.

Rudd BD, Burstein E, Duckett CS, Li X, Lukacs NW.

J Virol. 2005 Mar;79(6):3350-7.

40.

The small heat shock protein alpha B-crystallin is a novel inhibitor of TRAIL-induced apoptosis that suppresses the activation of caspase-3.

Kamradt MC, Lu M, Werner ME, Kwan T, Chen F, Strohecker A, Oshita S, Wilkinson JC, Yu C, Oliver PG, Duckett CS, Buchsbaum DJ, LoBuglio AF, Jordan VC, Cryns VL.

J Biol Chem. 2005 Mar 25;280(12):11059-66. Epub 2005 Jan 14.

41.

IAP proteins: sticking it to Smac.

Duckett CS.

Biochem J. 2005 Jan 1;385(Pt 1):e1-2.

42.

VIAF, a conserved inhibitor of apoptosis (IAP)-interacting factor that modulates caspase activation.

Wilkinson JC, Richter BW, Wilkinson AS, Burstein E, Rumble JM, Balliu B, Duckett CS.

J Biol Chem. 2004 Dec 3;279(49):51091-9. Epub 2004 Sep 15.

43.

Neutralization of Smac/Diablo by inhibitors of apoptosis (IAPs). A caspase-independent mechanism for apoptotic inhibition.

Wilkinson JC, Wilkinson AS, Scott FL, Csomos RA, Salvesen GS, Duckett CS.

J Biol Chem. 2004 Dec 3;279(49):51082-90. Epub 2004 Sep 15.

44.

Upstream regulatory role for XIAP in receptor-mediated apoptosis.

Wilkinson JC, Cepero E, Boise LH, Duckett CS.

Mol Cell Biol. 2004 Aug;24(16):7003-14.

45.

Smac/Diablo antagonizes ubiquitin ligase activity of inhibitor of apoptosis proteins.

Creagh EM, Murphy BM, Duriez PJ, Duckett CS, Martin SJ.

J Biol Chem. 2004 Jun 25;279(26):26906-14. Epub 2004 Apr 12.

46.
47.

Uncoupling of the signaling and caspase-inhibitory properties of X-linked inhibitor of apoptosis.

Lewis J, Burstein E, Reffey SB, Bratton SB, Roberts AB, Duckett CS.

J Biol Chem. 2004 Mar 5;279(10):9023-9. Epub 2003 Dec 29.

48.

A novel role for XIAP in copper homeostasis through regulation of MURR1.

Burstein E, Ganesh L, Dick RD, van De Sluis B, Wilkinson JC, Klomp LW, Wijmenga C, Brewer GJ, Nabel GJ, Duckett CS.

EMBO J. 2004 Jan 14;23(1):244-54. Epub 2003 Dec 18.

49.

The gene product Murr1 restricts HIV-1 replication in resting CD4+ lymphocytes.

Ganesh L, Burstein E, Guha-Niyogi A, Louder MK, Mascola JR, Klomp LW, Wijmenga C, Duckett CS, Nabel GJ.

Nature. 2003 Dec 18;426(6968):853-7.

50.

Dying for NF-kappaB? Control of cell death by transcriptional regulation of the apoptotic machinery.

Burstein E, Duckett CS.

Curr Opin Cell Biol. 2003 Dec;15(6):732-7. Review.

PMID:
14644198

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