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Items: 38

1.

Long-lasting correction of in vivo LTP and cognitive deficits of mice modelling Down syndrome with an α5-selective GABAA inverse agonist.

Duchon A, Gruart A, Albac C, Delatour B, Zorrilla de San Martin J, Delgado-García JM, Hérault Y, Potier MC.

Br J Pharmacol. 2019 Oct 25. doi: 10.1111/bph.14903. [Epub ahead of print]

PMID:
31652355
2.

TUBG1 missense variants underlying cortical malformations disrupt neuronal locomotion and microtubule dynamics but not neurogenesis.

Ivanova EL, Gilet JG, Sulimenko V, Duchon A, Rudolf G, Runge K, Collins SC, Asselin L, Broix L, Drouot N, Tilly P, Nusbaum P, Vincent A, Magnant W, Skory V, Birling MC, Pavlovic G, Godin JD, Yalcin B, Hérault Y, Dráber P, Chelly J, Hinckelmann MV.

Nat Commun. 2019 May 13;10(1):2129. doi: 10.1038/s41467-019-10081-8.

3.

Prenatal treatment with EGCG enriched green tea extract rescues GAD67 related developmental and cognitive defects in Down syndrome mouse models.

Souchet B, Duchon A, Gu Y, Dairou J, Chevalier C, Daubigney F, Nalesso V, Créau N, Yu Y, Janel N, Herault Y, Delabar JM.

Sci Rep. 2019 Mar 8;9(1):3914. doi: 10.1038/s41598-019-40328-9.

4.

Correction of cognitive deficits in mouse models of Down syndrome by a pharmacological inhibitor of DYRK1A.

Nguyen TL, Duchon A, Manousopoulou A, Loaëc N, Villiers B, Pani G, Karatas M, Mechling AE, Harsan LA, Limanton E, Bazureau JP, Carreaux F, Garbis SD, Meijer L, Herault Y.

Dis Model Mech. 2018 Sep 27;11(9). pii: dmm035634. doi: 10.1242/dmm.035634.

5.

SAMHD1 Impairs HIV-1 Gene Expression and Negatively Modulates Reactivation of Viral Latency in CD4+ T Cells.

Antonucci JM, Kim SH, St Gelais C, Bonifati S, Li TW, Buzovetsky O, Knecht KM, Duchon AA, Xiong Y, Musier-Forsyth K, Wu L.

J Virol. 2018 Jul 17;92(15). pii: e00292-18. doi: 10.1128/JVI.00292-18. Print 2018 Aug 1.

6.

HIV-1 Exploits a Dynamic Multi-aminoacyl-tRNA Synthetase Complex To Enhance Viral Replication.

Duchon AA, St Gelais C, Titkemeier N, Hatterschide J, Wu L, Musier-Forsyth K.

J Virol. 2017 Oct 13;91(21). pii: e01240-17. doi: 10.1128/JVI.01240-17. Print 2017 Nov 1.

7.

Inhibition of HIV-1 Gag-membrane interactions by specific RNAs.

Todd GC, Duchon A, Inlora J, Olson ED, Musier-Forsyth K, Ono A.

RNA. 2017 Mar;23(3):395-405. doi: 10.1261/rna.058453.116. Epub 2016 Dec 8.

8.

DYRK1A, a Dosage-Sensitive Gene Involved in Neurodevelopmental Disorders, Is a Target for Drug Development in Down Syndrome.

Duchon A, Herault Y.

Front Behav Neurosci. 2016 Jun 3;10:104. doi: 10.3389/fnbeh.2016.00104. eCollection 2016. Review.

9.

Pharmacological correction of excitation/inhibition imbalance in Down syndrome mouse models.

Souchet B, Guedj F, Penke-Verdier Z, Daubigney F, Duchon A, Herault Y, Bizot JC, Janel N, Créau N, Delatour B, Delabar JM.

Front Behav Neurosci. 2015 Oct 20;9:267. doi: 10.3389/fnbeh.2015.00267. eCollection 2015.

10.

Analysis of mammalian gene function through broad-based phenotypic screens across a consortium of mouse clinics.

de Angelis MH, Nicholson G, Selloum M, White J, Morgan H, Ramirez-Solis R, Sorg T, Wells S, Fuchs H, Fray M, Adams DJ, Adams NC, Adler T, Aguilar-Pimentel A, Ali-Hadji D, Amann G, André P, Atkins S, Auburtin A, Ayadi A, Becker J, Becker L, Bedu E, Bekeredjian R, Birling MC, Blake A, Bottomley J, Bowl M, Brault V, Busch DH, Bussell JN, Calzada-Wack J, Cater H, Champy MF, Charles P, Chevalier C, Chiani F, Codner GF, Combe R, Cox R, Dalloneau E, Dierich A, Di Fenza A, Doe B, Duchon A, Eickelberg O, Esapa CT, El Fertak L, Feigel T, Emelyanova I, Estabel J, Favor J, Flenniken A, Gambadoro A, Garrett L, Gates H, Gerdin AK, Gkoutos G, Greenaway S, Glasl L, Goetz P, Da Cruz IG, Götz A, Graw J, Guimond A, Hans W, Hicks G, Hölter SM, Höfler H, Hancock JM, Hoehndorf R, Hough T, Houghton R, Hurt A, Ivandic B, Jacobs H, Jacquot S, Jones N, Karp NA, Katus HA, Kitchen S, Klein-Rodewald T, Klingenspor M, Klopstock T, Lalanne V, Leblanc S, Lengger C, le Marchand E, Ludwig T, Lux A, McKerlie C, Maier H, Mandel JL, Marschall S, Mark M, Melvin DG, Meziane H, Micklich K, Mittelhauser C, Monassier L, Moulaert D, Muller S, Naton B, Neff F, Nolan PM, Nutter LM, Ollert M, Pavlovic G, Pellegata NS, Peter E, Petit-Demoulière B, Pickard A, Podrini C, Potter P, Pouilly L, Puk O, Richardson D, Rousseau S, Quintanilla-Fend L, Quwailid MM, Racz I, Rathkolb B, Riet F, Rossant J, Roux M, Rozman J, Ryder E, Salisbury J, Santos L, Schäble KH, Schiller E, Schrewe A, Schulz H, Steinkamp R, Simon M, Stewart M, Stöger C, Stöger T, Sun M, Sunter D, Teboul L, Tilly I, Tocchini-Valentini GP, Tost M, Treise I, Vasseur L, Velot E, Vogt-Weisenhorn D, Wagner C, Walling A, Weber B, Wendling O, Westerberg H, Willershäuser M, Wolf E, Wolter A, Wood J, Wurst W, Yildirim AÖ, Zeh R, Zimmer A, Zimprich A; EUMODIC Consortium, Holmes C, Steel KP, Herault Y, Gailus-Durner V, Mallon AM, Brown SD.

Nat Genet. 2015 Sep;47(9):969-978. doi: 10.1038/ng.3360. Epub 2015 Jul 27.

11.

Deletion of the App-Runx1 region in mice models human partial monosomy 21.

Arbogast T, Raveau M, Chevalier C, Nalesso V, Dembele D, Jacobs H, Wendling O, Roux M, Duchon A, Herault Y.

Dis Model Mech. 2015 Jun;8(6):623-34. doi: 10.1242/dmm.017814. Epub 2015 Apr 16.

12.

Opposite phenotypes of muscle strength and locomotor function in mouse models of partial trisomy and monosomy 21 for the proximal Hspa13-App region.

Brault V, Duchon A, Romestaing C, Sahun I, Pothion S, Karout M, Borel C, Dembele D, Bizot JC, Messaddeq N, Sharp AJ, Roussel D, Antonarakis SE, Dierssen M, Hérault Y.

PLoS Genet. 2015 Mar 24;11(3):e1005062. doi: 10.1371/journal.pgen.1005062. eCollection 2015 Mar.

13.

Dosage of the Abcg1-U2af1 region modifies locomotor and cognitive deficits observed in the Tc1 mouse model of Down syndrome.

Marechal D, Lopes Pereira P, Duchon A, Herault Y.

PLoS One. 2015 Feb 23;10(2):e0115302. doi: 10.1371/journal.pone.0115302. eCollection 2015.

14.

Excitation/inhibition balance and learning are modified by Dyrk1a gene dosage.

Souchet B, Guedj F, Sahún I, Duchon A, Daubigney F, Badel A, Yanagawa Y, Barallobre MJ, Dierssen M, Yu E, Herault Y, Arbones M, Janel N, Créau N, Delabar JM.

Neurobiol Dis. 2014 Sep;69:65-75. doi: 10.1016/j.nbd.2014.04.016. Epub 2014 May 4.

PMID:
24801365
15.

Epigallocatechin-3-gallate, a DYRK1A inhibitor, rescues cognitive deficits in Down syndrome mouse models and in humans.

De la Torre R, De Sola S, Pons M, Duchon A, de Lagran MM, Farré M, Fitó M, Benejam B, Langohr K, Rodriguez J, Pujadas M, Bizot JC, Cuenca A, Janel N, Catuara S, Covas MI, Blehaut H, Herault Y, Delabar JM, Dierssen M.

Mol Nutr Food Res. 2014 Feb;58(2):278-88. doi: 10.1002/mnfr.201300325. Epub 2013 Sep 14.

PMID:
24039182
16.

DYRK1A overexpression decreases plasma lecithin:cholesterol acyltransferase activity and apolipoprotein A-I levels.

Tlili A, Noll C, Middendorp S, Duchon A, Jouan M, Benabou E, Hérault Y, Paul JL, Delabar JM, Janel N.

Mol Genet Metab. 2013 Nov;110(3):371-7. doi: 10.1016/j.ymgme.2013.07.014. Epub 2013 Jul 20.

PMID:
23920041
17.

EsPal: one-stop shopping for Spanish word properties.

Duchon A, Perea M, Sebastián-Gallés N, Martí A, Carreiras M.

Behav Res Methods. 2013 Dec;45(4):1246-58. doi: 10.3758/s13428-013-0326-1.

PMID:
23468181
18.

Preface to the special section on methods for the analysis of communication.

Cooke NJ, Duchon A, Gorman JC, Keyton J, Miller A.

Hum Factors. 2012 Aug;54(4):485-8. No abstract available.

PMID:
22908673
19.

The App-Runx1 region is critical for birth defects and electrocardiographic dysfunctions observed in a Down syndrome mouse model.

Raveau M, Lignon JM, Nalesso V, Duchon A, Groner Y, Sharp AJ, Dembele D, Brault V, Hérault Y.

PLoS Genet. 2012 May;8(5):e1002724. doi: 10.1371/journal.pgen.1002724. Epub 2012 May 31.

20.

The in vivo Down syndrome genomic library in mouse.

Herault Y, Duchon A, Velot E, Maréchal D, Brault V.

Prog Brain Res. 2012;197:169-97. doi: 10.1016/B978-0-444-54299-1.00009-1.

PMID:
22541293
21.

Chronic Treatment with a Promnesiant GABA-A α5-Selective Inverse Agonist Increases Immediate Early Genes Expression during Memory Processing in Mice and Rectifies Their Expression Levels in a Down Syndrome Mouse Model.

Braudeau J, Dauphinot L, Duchon A, Loistron A, Dodd RH, Hérault Y, Delatour B, Potier MC.

Adv Pharmacol Sci. 2011;2011:153218. doi: 10.1155/2011/153218. Epub 2011 Oct 19.

22.

Identification of the translocation breakpoints in the Ts65Dn and Ts1Cje mouse lines: relevance for modeling Down syndrome.

Duchon A, Raveau M, Chevalier C, Nalesso V, Sharp AJ, Herault Y.

Mamm Genome. 2011 Dec;22(11-12):674-84. doi: 10.1007/s00335-011-9356-0. Epub 2011 Sep 28.

23.

Specific targeting of the GABA-A receptor α5 subtype by a selective inverse agonist restores cognitive deficits in Down syndrome mice.

Braudeau J, Delatour B, Duchon A, Pereira PL, Dauphinot L, de Chaumont F, Olivo-Marin JC, Dodd RH, Hérault Y, Potier MC.

J Psychopharmacol. 2011 Aug;25(8):1030-42. doi: 10.1177/0269881111405366. Epub 2011 Jun 21.

24.

Controlled somatic and germline copy number variation in the mouse model.

Hérault Y, Duchon A, Maréchal D, Raveau M, Pereira PL, Dalloneau E, Brault V.

Curr Genomics. 2010 Sep;11(6):470-80. doi: 10.2174/138920210793176038.

25.

The telomeric part of the human chromosome 21 from Cstb to Prmt2 is not necessary for the locomotor and short-term memory deficits observed in the Tc1 mouse model of Down syndrome.

Duchon A, Pothion S, Brault V, Sharp AJ, Tybulewicz VL, Fisher EM, Herault Y.

Behav Brain Res. 2011 Mar 1;217(2):271-81. doi: 10.1016/j.bbr.2010.10.023. Epub 2010 Oct 31.

26.

DYRK1A, a novel determinant of the methionine-homocysteine cycle in different mouse models overexpressing this Down-syndrome-associated kinase.

Noll C, Planque C, Ripoll C, Guedj F, Diez A, Ducros V, Belin N, Duchon A, Paul JL, Badel A, de Freminville B, Grattau Y, Bléhaut H, Herault Y, Janel N, Delabar JM.

PLoS One. 2009 Oct 21;4(10):e7540. doi: 10.1371/journal.pone.0007540.

27.

A new mouse model for the trisomy of the Abcg1-U2af1 region reveals the complexity of the combinatorial genetic code of down syndrome.

Pereira PL, Magnol L, Sahún I, Brault V, Duchon A, Prandini P, Gruart A, Bizot JC, Chadefaux-Vekemans B, Deutsch S, Trovero F, Delgado-García JM, Antonarakis SE, Dierssen M, Herault Y.

Hum Mol Genet. 2009 Dec 15;18(24):4756-69. doi: 10.1093/hmg/ddp438. Epub 2009 Sep 26.

28.

Inducing segmental aneuploid mosaicism in the mouse through targeted asymmetric sister chromatid event of recombination.

Duchon A, Besson V, Pereira PL, Magnol L, Hérault Y.

Genetics. 2008 Sep;180(1):51-9. doi: 10.1534/genetics.108.092312. Epub 2008 Aug 30.

29.

Modeling the monosomy for the telomeric part of human chromosome 21 reveals haploinsufficient genes modulating the inflammatory and airway responses.

Besson V, Brault V, Duchon A, Togbe D, Bizot JC, Quesniaux VF, Ryffel B, Hérault Y.

Hum Mol Genet. 2007 Sep 1;16(17):2040-52. Epub 2007 Jun 25.

PMID:
17591625
30.

Cre/loxP-mediated chromosome engineering of the mouse genome.

Brault V, Besson V, Magnol L, Duchon A, Hérault Y.

Handb Exp Pharmacol. 2007;(178):29-48. Review.

PMID:
17203650
31.

Humans do not switch between path knowledge and landmarks when learning a new environment.

Foo P, Duchon A, Warren WH Jr, Tarr MJ.

Psychol Res. 2007 May;71(3):240-51. Epub 2006 Sep 7.

PMID:
16957956
32.

Modeling chromosomes in mouse to explore the function of genes, genomic disorders, and chromosomal organization.

Brault V, Pereira P, Duchon A, Hérault Y.

PLoS Genet. 2006 Jul;2(7):e86. Review.

33.

Do humans integrate routes into a cognitive map? Map- versus landmark-based navigation of novel shortcuts.

Foo P, Warren WH, Duchon A, Tarr MJ.

J Exp Psychol Learn Mem Cogn. 2005 Mar;31(2):195-215.

PMID:
15755239
34.

A visual equalization strategy for locomotor control: of honeybees, robots, and humans.

Duchon AP, Warren WH Jr.

Psychol Sci. 2002 May;13(3):272-8.

PMID:
12009050
35.

Path integration from optic flow and body senses in a homing task.

Kearns MJ, Warren WH, Duchon AP, Tarr MJ.

Perception. 2002;31(3):349-74.

PMID:
11954696
36.

Optic flow is used to control human walking.

Warren WH Jr, Kay BA, Zosh WD, Duchon AP, Sahuc S.

Nat Neurosci. 2001 Feb;4(2):213-6.

PMID:
11175884
37.

The human visual system averages speed information.

Watamaniuk SN, Duchon A.

Vision Res. 1992 May;32(5):931-41.

PMID:
1604862
38.

Oxygen free radical involvement in ischemia and reperfusion injury to brain.

Cao W, Carney JM, Duchon A, Floyd RA, Chevion M.

Neurosci Lett. 1988 May 26;88(2):233-8.

PMID:
3380359

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