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Items: 9


Metabolic profiling of cancer cells reveals genome-wide crosstalk between transcriptional regulators and metabolism.

Ortmayr K, Dubuis S, Zampieri M.

Nat Commun. 2019 Apr 23;10(1):1841. doi: 10.1038/s41467-019-09695-9.


A framework for large-scale metabolome drug profiling links coenzyme A metabolism to the toxicity of anti-cancer drug dichloroacetate.

Dubuis S, Ortmayr K, Zampieri M.

Commun Biol. 2018 Aug 3;1:101. doi: 10.1038/s42003-018-0111-x. eCollection 2018.


6-Phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 is essential for p53-null cancer cells.

Ros S, Flöter J, Kaymak I, Da Costa C, Houddane A, Dubuis S, Griffiths B, Mitter R, Walz S, Blake S, Behrens A, Brindle KM, Zamboni N, Rider MH, Schulze A.

Oncogene. 2017 Jun 8;36(23):3287-3299. doi: 10.1038/onc.2016.477. Epub 2017 Jan 16.


Metabotypes of breast cancer cell lines revealed by non-targeted metabolomics.

Dubuis S, Baenke F, Scherbichler N, Alexander LT, Schulze A, Zamboni N.

Metab Eng. 2017 Sep;43(Pt B):173-186. doi: 10.1016/j.ymben.2016.12.009. Epub 2016 Dec 27.


Systems proteomics of liver mitochondria function.

Williams EG, Wu Y, Jha P, Dubuis S, Blattmann P, Argmann CA, Houten SM, Amariuta T, Wolski W, Zamboni N, Aebersold R, Auwerx J.

Science. 2016 Jun 10;352(6291):aad0189. doi: 10.1126/science.aad0189.


Functional screening identifies MCT4 as a key regulator of breast cancer cell metabolism and survival.

Baenke F, Dubuis S, Brault C, Weigelt B, Dankworth B, Griffiths B, Jiang M, Mackay A, Saunders B, Spencer-Dene B, Ros S, Stamp G, Reis-Filho JS, Howell M, Zamboni N, Schulze A.

J Pathol. 2015 Oct;237(2):152-65. doi: 10.1002/path.4562. Epub 2015 Jun 4.


Multilayered genetic and omics dissection of mitochondrial activity in a mouse reference population.

Wu Y, Williams EG, Dubuis S, Mottis A, Jovaisaite V, Houten SM, Argmann CA, Faridi P, Wolski W, Kutalik Z, Zamboni N, Auwerx J, Aebersold R.

Cell. 2014 Sep 11;158(6):1415-1430. doi: 10.1016/j.cell.2014.07.039.


D-Glucosamine supplementation extends life span of nematodes and of ageing mice.

Weimer S, Priebs J, Kuhlow D, Groth M, Priebe S, Mansfeld J, Merry TL, Dubuis S, Laube B, Pfeiffer AF, Schulz TJ, Guthke R, Platzer M, Zamboni N, Zarse K, Ristow M.

Nat Commun. 2014 Apr 8;5:3563. doi: 10.1038/ncomms4563.


Evolution of nucleosome occupancy: conservation of global properties and divergence of gene-specific patterns.

Tsui K, Dubuis S, Gebbia M, Morse RH, Barkai N, Tirosh I, Nislow C.

Mol Cell Biol. 2011 Nov;31(21):4348-55. doi: 10.1128/MCB.05276-11. Epub 2011 Sep 6.

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