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Items: 1 to 50 of 71

1.

Xenobiotic Receptors and Their Mates in Atopic Dermatitis.

Minzaghi D, Pavel P, Dubrac S.

Int J Mol Sci. 2019 Aug 29;20(17). pii: E4234. doi: 10.3390/ijms20174234. Review.

2.

Induced pluripotent stem cell line heterozygous for p.R501X mutation in filaggrin: KCLi003-A.

Kolundzic N, Khurana P, Devito L, Jeriha J, Marx J, Hobbs C, Wong XFCC, Common JEA, Liovic M, Dubrac S, Gruber R, Schmuth M, Mauro TM, Ilic D.

Stem Cell Res. 2019 Aug;39:101527. doi: 10.1016/j.scr.2019.101527. Epub 2019 Aug 7.

3.

3D-Organotypic Cultures to Unravel Molecular and Cellular Abnormalities in Atopic Dermatitis and Ichthyosis Vulgaris.

Leman G, Moosbrugger-Martinz V, Blunder S, Pavel P, Dubrac S.

Cells. 2019 May 22;8(5). pii: E489. doi: 10.3390/cells8050489. Review.

4.

Induced pluripotent stem cell line heterozygous for p.R2447X mutation in filaggrin: KCLi002-A.

Kolundzic N, Khurana P, Devito L, Donne M, Hobbs C, Jeriha J, Wong XFCC, Common JAE, Lane EB, Dubrac S, Gruber R, Schmuth M, Mauro TM, Ilic D.

Stem Cell Res. 2019 Jul;38:101462. doi: 10.1016/j.scr.2019.101462. Epub 2019 May 13.

5.

Filaggrin null mutations are associated with altered circulating Tregs in atopic dermatitis.

Moosbrugger-Martinz V, Gruber R, Ladstätter K, Bellutti M, Blunder S, Schmuth M, Dubrac S.

J Cell Mol Med. 2019 Feb;23(2):1288-1299. doi: 10.1111/jcmm.14031. Epub 2018 Dec 4.

6.

In Vivo Applicability of Neosartorya fischeri Antifungal Protein 2 (NFAP2) in Treatment of Vulvovaginal Candidiasis.

Kovács R, Holzknecht J, Hargitai Z, Papp C, Farkas A, Borics A, Tóth L, Váradi G, Tóth GK, Kovács I, Dubrac S, Majoros L, Marx F, Galgóczy L.

Antimicrob Agents Chemother. 2019 Jan 29;63(2). pii: e01777-18. doi: 10.1128/AAC.01777-18. Print 2019 Feb.

7.

The Evolutionary Conserved γ-Core Motif Influences the Anti-Candida Activity of the Penicillium chrysogenum Antifungal Protein PAF.

Sonderegger C, Váradi G, Galgóczy L, Kocsubé S, Posch W, Borics A, Dubrac S, Tóth GK, Wilflingseder D, Marx F.

Front Microbiol. 2018 Jul 20;9:1655. doi: 10.3389/fmicb.2018.01655. eCollection 2018.

8.

Induced pluripotent stem cell line from an atopic dermatitis patient heterozygous for c.2282del4 mutation in filaggrin: KCLi001-A.

Devito L, Donne M, Kolundzic N, Khurana P, Hobbs C, Kaddour G, Dubrac S, Gruber R, Schmuth M, Mauro T, Ilic D.

Stem Cell Res. 2018 Aug;31:122-126. doi: 10.1016/j.scr.2018.07.014. Epub 2018 Jul 25.

9.

SpdC, a novel virulence factor, controls histidine kinase activity in Staphylococcus aureus.

Poupel O, Proux C, Jagla B, Msadek T, Dubrac S.

PLoS Pathog. 2018 Mar 15;14(3):e1006917. doi: 10.1371/journal.ppat.1006917. eCollection 2018 Mar.

10.

Erratum.

Lioliou E, Fechter P, Caldelari I, Jester BC, Dubrac S, Helfer AC, Boisset S, Vandenesch F, Romby P, Geissmann T.

RNA Biol. 2017 Dec 2;14(12):1827. doi: 10.1080/15476286.2016.1184436. No abstract available.

11.

Structure and function of the Leptospira interrogans peroxide stress regulator (PerR), an atypical PerR devoid of a structural metal-binding site.

Kebouchi M, Saul F, Taher R, Landier A, Beaudeau B, Dubrac S, Weber P, Haouz A, Picardeau M, Benaroudj N.

J Biol Chem. 2018 Jan 12;293(2):497-509. doi: 10.1074/jbc.M117.804443. Epub 2017 Nov 16.

12.

Epidermal Overexpression of Xenobiotic Receptor PXR Impairs the Epidermal Barrier and Triggers Th2 Immune Response.

Elentner A, Schmuth M, Yannoutsos N, Eichmann TO, Gruber R, Radner FPW, Hermann M, Del Frari B, Dubrac S.

J Invest Dermatol. 2018 Jan;138(1):109-120. doi: 10.1016/j.jid.2017.07.846. Epub 2017 Sep 18.

13.

Enhanced Expression of Genes Related to Xenobiotic Metabolism in the Skin of Patients with Atopic Dermatitis but Not with Ichthyosis Vulgaris.

Blunder S, Kõks S, Kõks G, Reimann E, Hackl H, Gruber R, Moosbrugger-Martinz V, Schmuth M, Dubrac S.

J Invest Dermatol. 2018 Jan;138(1):98-108. doi: 10.1016/j.jid.2017.08.036. Epub 2017 Sep 9.

14.

2nd Science Days of the Austrian Society of Dermatology and Venereology (ÖGDV Forschungstage).

Stary G, Dubrac S, Gruber F, Paulitschke V, Prodinger C, Schmuth M.

J Dtsch Dermatol Ges. 2017 Apr;15(4):475-476. doi: 10.1111/ddg.13196. No abstract available.

PMID:
28378492
15.

Methodology for the Study of Horizontal Gene Transfer in Staphylococcus aureus.

Cafini F, Thi Le Thuy N, Román F, Prieto J, Dubrac S, Msadek T, Morikawa K.

J Vis Exp. 2017 Mar 10;(121). doi: 10.3791/55087.

16.

Langerhans cells and NK cells cooperate in the inhibition of chemical skin carcinogenesis.

Ortner D, Tripp CH, Komenda K, Dubrac S, Zelger B, Hermann M, Doppler W, Tymoszuk PZ, Boon L, Clausen BE, Stoitzner P.

Oncoimmunology. 2016 Nov 18;6(2):e1260215. doi: 10.1080/2162402X.2016.1260215. eCollection 2017.

17.

A Mouse Model for Atopic Dermatitis Using Topical Application of Vitamin D3 or of Its Analog MC903.

Moosbrugger-Martinz V, Schmuth M, Dubrac S.

Methods Mol Biol. 2017;1559:91-106. doi: 10.1007/978-1-4939-6786-5_8.

PMID:
28063040
18.

Alterations in Epidermal Eicosanoid Metabolism Contribute to Inflammation and Impaired Late Differentiation in FLG-Mutated Atopic Dermatitis.

Blunder S, Rühl R, Moosbrugger-Martinz V, Krimmel C, Geisler A, Zhu H, Crumrine D, Elias PM, Gruber R, Schmuth M, Dubrac S.

J Invest Dermatol. 2017 Mar;137(3):706-715. doi: 10.1016/j.jid.2016.09.034. Epub 2016 Oct 26.

19.

PNPLA1 Deficiency in Mice and Humans Leads to a Defect in the Synthesis of Omega-O-Acylceramides.

Grond S, Eichmann TO, Dubrac S, Kolb D, Schmuth M, Fischer J, Crumrine D, Elias PM, Haemmerle G, Zechner R, Lass A, Radner FPW.

J Invest Dermatol. 2017 Feb;137(2):394-402. doi: 10.1016/j.jid.2016.08.036. Epub 2016 Oct 14.

20.

UVB-Induced Senescence of Human Dermal Fibroblasts Involves Impairment of Proteasome and Enhanced Autophagic Activity.

Cavinato M, Koziel R, Romani N, Weinmüllner R, Jenewein B, Hermann M, Dubrac S, Ratzinger G, Grillari J, Schmuth M, Jansen-Dürr P.

J Gerontol A Biol Sci Med Sci. 2017 May 1;72(5):632-639. doi: 10.1093/gerona/glw150.

PMID:
27516623
21.

1st Science Days of the Austrian Society of Dermatology and Venereology (ÖGDV Forschungstage).

Schmuth M, Dubrac S, Gruber F, Paulitschke V, Prodinger C, Stary G, Aberer W, Pehamberger H, Stingl G.

J Dtsch Dermatol Ges. 2016 Apr;14(4):446-7. doi: 10.1111/ddg.13004. No abstract available.

PMID:
27027766
22.

Transcriptional Analysis and Subcellular Protein Localization Reveal Specific Features of the Essential WalKR System in Staphylococcus aureus.

Poupel O, Moyat M, Groizeleau J, Antunes LC, Gribaldo S, Msadek T, Dubrac S.

PLoS One. 2016 Mar 21;11(3):e0151449. doi: 10.1371/journal.pone.0151449. eCollection 2016.

23.

Atopic dermatitis induces the expansion of thymus-derived regulatory T cells exhibiting a Th2-like phenotype in mice.

Moosbrugger-Martinz V, Tripp CH, Clausen BE, Schmuth M, Dubrac S.

J Cell Mol Med. 2016 May;20(5):930-8. doi: 10.1111/jcmm.12806. Epub 2016 Mar 2.

24.

Various checkpoints prevent the synthesis of Staphylococcus aureus peptidoglycan hydrolase LytM in the stationary growth phase.

Lioliou E, Fechter P, Caldelari I, Jester BC, Dubrac S, Helfer AC, Boisset S, Vandenesch F, Romby P, Geissmann T.

RNA Biol. 2016;13(4):427-40. doi: 10.1080/15476286.2016.1153209. Epub 2016 Feb 22. Erratum in: RNA Biol. 2017 Dec 2;14(12):1827.

25.

Epidermal barrier in hereditary ichthyoses, atopic dermatitis, and psoriasis.

Schmuth M, Blunder S, Dubrac S, Gruber R, Moosbrugger-Martinz V.

J Dtsch Dermatol Ges. 2015 Nov;13(11):1119-23. doi: 10.1111/ddg.12827. Review.

PMID:
26513068
26.

Skin response to a carcinogen involves the xenobiotic receptor pregnane X receptor.

Elentner A, Ortner D, Clausen B, Gonzalez FJ, Fernández-Salguero PM, Schmuth M, Dubrac S.

Exp Dermatol. 2015 Nov;24(11):835-40. doi: 10.1111/exd.12766. Epub 2015 Jul 14.

27.

Differentiation between acute skin rejection in allotransplantation and T-cell mediated skin inflammation based on gene expression analysis.

Wolfram D, Morandi EM, Eberhart N, Hautz T, Hackl H, Zelger B, Riede G, Wachter T, Dubrac S, Ploner C, Pierer G, Schneeberger S.

Biomed Res Int. 2015;2015:259160. doi: 10.1155/2015/259160. Epub 2015 Feb 12.

28.

Single cell stochastic regulation of pilus phase variation by an attenuation-like mechanism.

Danne C, Dubrac S, Trieu-Cuot P, Dramsi S.

PLoS Pathog. 2014 Jan;10(1):e1003860. doi: 10.1371/journal.ppat.1003860. Epub 2014 Jan 16.

29.

Role of PPAR, LXR, and PXR in epidermal homeostasis and inflammation.

Schmuth M, Moosbrugger-Martinz V, Blunder S, Dubrac S.

Biochim Biophys Acta. 2014 Mar;1841(3):463-73. doi: 10.1016/j.bbalip.2013.11.012. Epub 2013 Dec 3. Review.

PMID:
24315978
30.

Allergen-induced dermatitis causes alterations in cutaneous retinoid-mediated signaling in mice.

Gericke J, Ittensohn J, Mihály J, Dubrac S, Rühl R.

PLoS One. 2013 Aug 15;8(8):e71244. doi: 10.1371/journal.pone.0071244. eCollection 2013.

31.

Identification of DNA binding motifs of the Mycobacterium tuberculosis PhoP/PhoR two-component signal transduction system.

Cimino M, Thomas C, Namouchi A, Dubrac S, Gicquel B, Gopaul DN.

PLoS One. 2012;7(8):e42876. doi: 10.1371/journal.pone.0042876. Epub 2012 Aug 7.

32.

The WalKR system controls major staphylococcal virulence genes and is involved in triggering the host inflammatory response.

Delauné A, Dubrac S, Blanchet C, Poupel O, Mäder U, Hiron A, Leduc A, Fitting C, Nicolas P, Cavaillon JM, Adib-Conquy M, Msadek T.

Infect Immun. 2012 Oct;80(10):3438-53. doi: 10.1128/IAI.00195-12. Epub 2012 Jul 23.

33.

Rga, a RofA-like regulator, is the major transcriptional activator of the PI-2a pilus in Streptococcus agalactiae.

Dramsi S, Dubrac S, Konto-Ghiorghi Y, Da Cunha V, Couvé E, Glaser P, Caliot E, Débarbouillé M, Bellais S, Trieu-Cuot P, Mistou MY.

Microb Drug Resist. 2012 Jun;18(3):286-97. doi: 10.1089/mdr.2012.0005. Epub 2012 Mar 20.

PMID:
22432704
34.

PPAR-alpha in cutaneous inflammation.

Dubrac S, Schmuth M.

Dermatoendocrinol. 2011 Jan;3(1):23-6. doi: 10.4161/derm.3.1.14615.

35.

Lack of IL-2 in PPAR-α-deficient mice triggers allergic contact dermatitis by affecting regulatory T cells.

Dubrac S, Elentner A, Schoonjans K, Auwerx J, Schmuth M.

Eur J Immunol. 2011 Jul;41(7):1980-91. doi: 10.1002/eji.201041357. Epub 2011 Jun 6.

36.

Peptidoglycan crosslinking relaxation plays an important role in Staphylococcus aureus WalKR-dependent cell viability.

Delaune A, Poupel O, Mallet A, Coic YM, Msadek T, Dubrac S.

PLoS One. 2011 Feb 28;6(2):e17054. doi: 10.1371/journal.pone.0017054.

37.

CD34+ -derived Langerhans cell-like cells are different from epidermal Langerhans cells in their response to thymic stromal lymphopoietin.

Nguyen VA, Dubrac S, Forstner M, Huter O, Del Frari B, Romani N, Ebner S.

J Cell Mol Med. 2011 Sep;15(9):1847-56. doi: 10.1111/j.1582-4934.2010.01206.x.

38.

The pleiotropic CymR regulator of Staphylococcus aureus plays an important role in virulence and stress response.

Soutourina O, Dubrac S, Poupel O, Msadek T, Martin-Verstraete I.

PLoS Pathog. 2010 May 13;6(5):e1000894. doi: 10.1371/journal.ppat.1000894.

39.

Atopic dermatitis: the role of Langerhans cells in disease pathogenesis.

Dubrac S, Schmuth M, Ebner S.

Immunol Cell Biol. 2010 May-Jun;88(4):400-9. doi: 10.1038/icb.2010.33. Epub 2010 Mar 30. Review.

PMID:
20351749
40.

Modulation of T lymphocyte function by the pregnane X receptor.

Dubrac S, Elentner A, Ebner S, Horejs-Hoeck J, Schmuth M.

J Immunol. 2010 Mar 15;184(6):2949-57. doi: 10.4049/jimmunol.0902151. Epub 2010 Feb 19.

41.

Novel antibacterial compounds specifically targeting the essential WalR response regulator.

Gotoh Y, Doi A, Furuta E, Dubrac S, Ishizaki Y, Okada M, Igarashi M, Misawa N, Yoshikawa H, Okajima T, Msadek T, Utsumi R.

J Antibiot (Tokyo). 2010 Mar;63(3):127-34. doi: 10.1038/ja.2010.4. Epub 2010 Jan 29.

PMID:
20111065
42.

Langerhans cells are critical in the development of atopic dermatitis-like inflammation and symptoms in mice.

Elentner A, Finke D, Schmuth M, Chappaz S, Ebner S, Malissen B, Kissenpfennig A, Romani N, Dubrac S.

J Cell Mol Med. 2009 Aug;13(8B):2658-72. doi: 10.1111/j.1582-4934.2009.00797.x. Epub 2009 Jun 16.

43.

The Pta-AckA pathway controlling acetyl phosphate levels and the phosphorylation state of the DegU orphan response regulator both play a role in regulating Listeria monocytogenes motility and chemotaxis.

Gueriri I, Bay S, Dubrac S, Cyncynatus C, Msadek T.

Mol Microbiol. 2008 Dec;70(6):1342-57. doi: 10.1111/j.1365-2958.2008.06496.x. Epub 2008 Oct 17.

44.

A matter of life and death: cell wall homeostasis and the WalKR (YycGF) essential signal transduction pathway.

Dubrac S, Bisicchia P, Devine KM, Msadek T.

Mol Microbiol. 2008 Dec;70(6):1307-22. doi: 10.1111/j.1365-2958.2008.06483.x. Epub 2008 Oct 23. Review.

45.

Tearing down the wall: peptidoglycan metabolism and the WalK/WalR (YycG/YycF) essential two-component system.

Dubrac S, Msadek T.

Adv Exp Med Biol. 2008;631:214-28. doi: 10.1007/978-0-387-78885-2_15. Review.

PMID:
18792692
46.

The DegU orphan response regulator of Listeria monocytogenes autorepresses its own synthesis and is required for bacterial motility, virulence and biofilm formation.

Gueriri I, Cyncynatus C, Dubrac S, Arana AT, Dussurget O, Msadek T.

Microbiology. 2008 Aug;154(Pt 8):2251-64. doi: 10.1099/mic.0.2008/017590-0.

PMID:
18667558
47.

The Listeria monocytogenes virulence factor InlJ is specifically expressed in vivo and behaves as an adhesin.

Sabet C, Toledo-Arana A, Personnic N, Lecuit M, Dubrac S, Poupel O, Gouin E, Nahori MA, Cossart P, Bierne H.

Infect Immun. 2008 Apr;76(4):1368-78. doi: 10.1128/IAI.01519-07. Epub 2008 Jan 28.

48.

Thematic review series: skin lipids. Peroxisome proliferator-activated receptors and liver X receptors in epidermal biology.

Schmuth M, Jiang YJ, Dubrac S, Elias PM, Feingold KR.

J Lipid Res. 2008 Mar;49(3):499-509. doi: 10.1194/jlr.R800001-JLR200. Epub 2008 Jan 8. Review.

50.

Peroxisome proliferator-activated receptor-alpha activation inhibits Langerhans cell function.

Dubrac S, Stoitzner P, Pirkebner D, Elentner A, Schoonjans K, Auwerx J, Saeland S, Hengster P, Fritsch P, Romani N, Schmuth M.

J Immunol. 2007 Apr 1;178(7):4362-72.

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