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Items: 27

1.

Brain Injury-Mediated Neuroinflammatory Response and Alzheimer's Disease.

Kempuraj D, Ahmed ME, Selvakumar GP, Thangavel R, Dhaliwal AS, Dubova I, Mentor S, Premkumar K, Saeed D, Zahoor H, Raikwar SP, Zaheer S, Iyer SS, Zaheer A.

Neuroscientist. 2019 May 16:1073858419848293. doi: 10.1177/1073858419848293. [Epub ahead of print]

PMID:
31092147
2.

Next Generation Precision Medicine: CRISPR-mediated Genome Editing for the Treatment of Neurodegenerative Disorders.

Raikwar SP, Kikkeri NS, Sakuru R, Saeed D, Zahoor H, Premkumar K, Mentor S, Thangavel R, Dubova I, Ahmed ME, Selvakumar GP, Kempuraj D, Zaheer S, Iyer SS, Zaheer A.

J Neuroimmune Pharmacol. 2019 Apr 23. doi: 10.1007/s11481-019-09849-y. [Epub ahead of print] Review.

PMID:
31011884
3.

Synergy in Disruption of Mitochondrial Dynamics by Aβ (1-42) and Glia Maturation Factor (GMF) in SH-SY5Y Cells Is Mediated Through Alterations in Fission and Fusion Proteins.

Ahmed ME, Selvakumar GP, Kempuraj D, Thangavel R, Mentor S, Dubova I, Raikwar SP, Zaheer S, Iyer S, Zaheer A.

Mol Neurobiol. 2019 Apr 4. doi: 10.1007/s12035-019-1544-z. [Epub ahead of print]

PMID:
30949973
4.

Mast Cells in Stress, Pain, Blood-Brain Barrier, Neuroinflammation and Alzheimer's Disease.

Kempuraj D, Mentor S, Thangavel R, Ahmed ME, Selvakumar GP, Raikwar SP, Dubova I, Zaheer S, Iyer SS, Zaheer A.

Front Cell Neurosci. 2019 Feb 19;13:54. doi: 10.3389/fncel.2019.00054. eCollection 2019.

5.

CRISPR/Cas9 Editing of Glia Maturation Factor Regulates Mitochondrial Dynamics by Attenuation of the NRF2/HO-1 Dependent Ferritin Activation in Glial Cells.

Selvakumar GP, Ahmed ME, Raikwar SP, Thangavel R, Kempuraj D, Dubova I, Saeed D, Zahoor H, Premkumar K, Zaheer S, Iyer S, Zaheer A.

J Neuroimmune Pharmacol. 2019 Feb 27. doi: 10.1007/s11481-019-09833-6. [Epub ahead of print]

PMID:
30810907
6.

Glia Maturation Factor and Mast Cell-Dependent Expression of Inflammatory Mediators and Proteinase Activated Receptor-2 in Neuroinflammation.

Kempuraj D, Selvakumar GP, Thangavel R, Ahmed ME, Zaheer S, Kumar KK, Yelam A, Kaur H, Dubova I, Raikwar SP, Iyer SS, Zaheer A.

J Alzheimers Dis. 2018;66(3):1117-1129. doi: 10.3233/JAD-180786.

7.

Molecular Association of Glia Maturation Factor with the Autophagic Machinery in Rat Dopaminergic Neurons: a Role for Endoplasmic Reticulum Stress and MAPK Activation.

Selvakumar GP, Iyer SS, Kempuraj D, Ahmed ME, Thangavel R, Dubova I, Raikwar SP, Zaheer S, Zaheer A.

Mol Neurobiol. 2019 Jun;56(6):3865-3881. doi: 10.1007/s12035-018-1340-1. Epub 2018 Sep 14.

8.

Neuro-Immuno-Gene- and Genome-Editing-Therapy for Alzheimer's Disease: Are We There Yet?

Raikwar SP, Thangavel R, Dubova I, Ahmed ME, Selvakumar PG, Kempuraj D, Zaheer S, Iyer S, Zaheer A.

J Alzheimers Dis. 2018;65(2):321-344. doi: 10.3233/JAD-180422.

9.

Mast Cell Proteases Activate Astrocytes and Glia-Neurons and Release Interleukin-33 by Activating p38 and ERK1/2 MAPKs and NF-κB.

Kempuraj D, Thangavel R, Selvakumar GP, Ahmed ME, Zaheer S, Raikwar SP, Zahoor H, Saeed D, Dubova I, Giler G, Herr S, Iyer SS, Zaheer A.

Mol Neurobiol. 2019 Mar;56(3):1681-1693. doi: 10.1007/s12035-018-1177-7. Epub 2018 Jun 18.

PMID:
29916143
10.

Are Tanycytes the Missing Link Between Type 2 Diabetes and Alzheimer's Disease?

Raikwar SP, Bhagavan SM, Ramaswamy SB, Thangavel R, Dubova I, Selvakumar GP, Ahmed ME, Kempuraj D, Zaheer S, Iyer S, Zaheer A.

Mol Neurobiol. 2019 Feb;56(2):833-843. doi: 10.1007/s12035-018-1123-8. Epub 2018 May 24. Review.

11.

Targeted Gene Editing of Glia Maturation Factor in Microglia: a Novel Alzheimer's Disease Therapeutic Target.

Raikwar SP, Thangavel R, Dubova I, Selvakumar GP, Ahmed ME, Kempuraj D, Zaheer SA, Iyer SS, Zaheer A.

Mol Neurobiol. 2019 Jan;56(1):378-393. doi: 10.1007/s12035-018-1068-y. Epub 2018 Apr 27.

12.

Establishment of human iPSC-based models for the study and targeting of glioma initiating cells.

Sancho-Martinez I, Nivet E, Xia Y, Hishida T, Aguirre A, Ocampo A, Ma L, Morey R, Krause MN, Zembrzycki A, Ansorge O, Vazquez-Ferrer E, Dubova I, Reddy P, Lam D, Hishida Y, Wu MZ, Esteban CR, O'Leary D, Wahl GM, Verma IM, Laurent LC, Izpisua Belmonte JC.

Nat Commun. 2016 Feb 22;7:10743. doi: 10.1038/ncomms10743.

13.

Conversion of human fibroblasts into monocyte-like progenitor cells.

Pulecio J, Nivet E, Sancho-Martinez I, Vitaloni M, Guenechea G, Xia Y, Kurian L, Dubova I, Bueren J, Laricchia-Robbio L, Belmonte JCI.

Stem Cells. 2014 Nov;32(11):2923-2938. doi: 10.1002/stem.1800.

14.

Modelling Fanconi anemia pathogenesis and therapeutics using integration-free patient-derived iPSCs.

Liu GH, Suzuki K, Li M, Qu J, Montserrat N, Tarantino C, Gu Y, Yi F, Xu X, Zhang W, Ruiz S, Plongthongkum N, Zhang K, Masuda S, Nivet E, Tsunekawa Y, Soligalla RD, Goebl A, Aizawa E, Kim NY, Kim J, Dubova I, Li Y, Ren R, Benner C, Del Sol A, Bueren J, Trujillo JP, Surralles J, Cappelli E, Dufour C, Esteban CR, Belmonte JCI.

Nat Commun. 2014 Jul 7;5:4330. doi: 10.1038/ncomms5330.

15.

Directed differentiation of human pluripotent cells to ureteric bud kidney progenitor-like cells.

Xia Y, Nivet E, Sancho-Martinez I, Gallegos T, Suzuki K, Okamura D, Wu MZ, Dubova I, Esteban CR, Montserrat N, Campistol JM, Izpisua Belmonte JC.

Nat Cell Biol. 2013 Dec;15(12):1507-15. doi: 10.1038/ncb2872. Epub 2013 Nov 17.

PMID:
24240476
16.

Conversion of human fibroblasts to angioblast-like progenitor cells.

Kurian L, Sancho-Martinez I, Nivet E, Aguirre A, Moon K, Pendaries C, Volle-Challier C, Bono F, Herbert JM, Pulecio J, Xia Y, Li M, Montserrat N, Ruiz S, Dubova I, Rodriguez C, Denli AM, Boscolo FS, Thiagarajan RD, Gage FH, Loring JF, Laurent LC, Izpisua Belmonte JC.

Nat Methods. 2013 Jan;10(1):77-83. doi: 10.1038/nmeth.2255. Epub 2012 Dec 2.

17.

Progressive degeneration of human neural stem cells caused by pathogenic LRRK2.

Liu GH, Qu J, Suzuki K, Nivet E, Li M, Montserrat N, Yi F, Xu X, Ruiz S, Zhang W, Wagner U, Kim A, Ren B, Li Y, Goebl A, Kim J, Soligalla RD, Dubova I, Thompson J, Yates J 3rd, Esteban CR, Sancho-Martinez I, Izpisua Belmonte JC.

Nature. 2012 Nov 22;491(7425):603-7. doi: 10.1038/nature11557. Epub 2012 Oct 17.

18.

Efficient correction of hemoglobinopathy-causing mutations by homologous recombination in integration-free patient iPSCs.

Li M, Suzuki K, Qu J, Saini P, Dubova I, Yi F, Lee J, Sancho-Martinez I, Liu GH, Izpisua Belmonte JC.

Cell Res. 2011 Dec;21(12):1740-4. doi: 10.1038/cr.2011.186. Epub 2011 Nov 22. No abstract available.

19.

Targeted gene correction of laminopathy-associated LMNA mutations in patient-specific iPSCs.

Liu GH, Suzuki K, Qu J, Sancho-Martinez I, Yi F, Li M, Kumar S, Nivet E, Kim J, Soligalla RD, Dubova I, Goebl A, Plongthongkum N, Fung HL, Zhang K, Loring JF, Laurent LC, Izpisua Belmonte JC.

Cell Stem Cell. 2011 Jun 3;8(6):688-94. doi: 10.1016/j.stem.2011.04.019. Epub 2011 May 19.

20.

Pitx2 regulates gonad morphogenesis.

Rodríguez-León J, Rodríguez Esteban C, Martí M, Santiago-Josefat B, Dubova I, Rubiralta X, Izpisúa Belmonte JC.

Proc Natl Acad Sci U S A. 2008 Aug 12;105(32):11242-7. doi: 10.1073/pnas.0804904105. Epub 2008 Aug 4.

21.

Wnt/beta-catenin signaling regulates vertebrate limb regeneration.

Kawakami Y, Rodriguez Esteban C, Raya M, Kawakami H, Martí M, Dubova I, Izpisúa Belmonte JC.

Genes Dev. 2006 Dec 1;20(23):3232-7. Epub 2006 Nov 17.

22.

[Diagnostics and differential diagnostics of bronchial asthma and chronic obstructive pulmonary disease].

Kobylianskiĭ VI, Fenin AL, Izvekova AV, Dubova II, Nazarova LV, Gamal' EA.

Klin Med (Mosk). 2006;84(2):20-3. Russian.

PMID:
16613000
23.

Characterization of NF-kappa B/I kappa B proteins in zebra fish and their involvement in notochord development.

Correa RG, Tergaonkar V, Ng JK, Dubova I, Izpisua-Belmonte JC, Verma IM.

Mol Cell Biol. 2004 Jun;24(12):5257-68.

24.

Notch activity induces Nodal expression and mediates the establishment of left-right asymmetry in vertebrate embryos.

Raya A, Kawakami Y, Rodriguez-Esteban C, Buscher D, Koth CM, Itoh T, Morita M, Raya RM, Dubova I, Bessa JG, de la Pompa JL, Izpisua Belmonte JC.

Genes Dev. 2003 May 15;17(10):1213-8. Epub 2003 May 2.

25.

[Variability of anthropometric traits in newborn offspring of Russian-Buryat unions].

Dubova IuE, Bogatyreva LV.

Genetika. 1993 Oct;29(10):1702-11. Russian.

PMID:
8307358
26.

The importance of the diffusive transfer of tints in the technology of tinting of soft contact lenses.

Polishchuk AYa, Iordanskii AL, Zaikov GE, Varshavsky VL, Yagodkina TA, Dubova IG, Madyuskin NN.

J Biomed Mater Res. 1991 Mar;25(3):367-71.

PMID:
2026641
27.

[Comparative evaluation of the possible postoperative astigmatism in using different shapes of cataract incision].

Avetisov SE, Mamikonian VR, Dubova IG.

Vestn Oftalmol. 1987 Jul-Aug;103(4):14-5. Russian. No abstract available.

PMID:
3672696

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