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Items: 1 to 50 of 145

1.

The Timing of Melatonin Administration Is Crucial for Its Antidepressant-Like Effect in Mice.

Estrada-Reyes R, Valdés-Tovar M, Arrieta-Baez D, Dorantes-Barrón AM, Quero-Chávez D, Solís-Chagoyán H, Argueta J, Dubocovich ML, Benítez-King G.

Int J Mol Sci. 2018 Aug 3;19(8). pii: E2278. doi: 10.3390/ijms19082278.

2.

Circadian modulation of neuroplasticity by melatonin: a target in the treatment of depression.

Valdés-Tovar M, Estrada-Reyes R, Solís-Chagoyán H, Argueta J, Dorantes-Barrón AM, Quero-Chávez D, Cruz-Garduño R, Cercós MG, Trueta C, Oikawa-Sala J, Dubocovich ML, Benítez-King G.

Br J Pharmacol. 2018 Aug;175(16):3200-3208. doi: 10.1111/bph.14197. Epub 2018 Apr 17. Review.

PMID:
29512136
3.

Food-induced reinforcement is abrogated by the genetic deletion of the MT1 or MT2 melatonin receptor in C3H/HeN mice.

Clough SJ, Hudson RL, Dubocovich ML.

Behav Brain Res. 2018 May 2;343:28-35. doi: 10.1016/j.bbr.2018.01.027. Epub 2018 Jan 31.

4.

Role of the MT1 and MT2 melatonin receptors in mediating depressive- and anxiety-like behaviors in C3H/HeN mice.

Liu J, Clough SJ, Dubocovich ML.

Genes Brain Behav. 2017 Jun;16(5):546-553. doi: 10.1111/gbb.12369. Epub 2017 Feb 20.

5.

Carbamate Insecticides Target Human Melatonin Receptors.

Popovska-Gorevski M, Dubocovich ML, Rajnarayanan RV.

Chem Res Toxicol. 2017 Feb 20;30(2):574-582. doi: 10.1021/acs.chemrestox.6b00301. Epub 2017 Jan 11.

6.

Learned motivation drives circadian physiology in the absence of the master circadian clock.

Rawashdeh O, Clough SJ, Hudson RL, Dubocovich ML.

FASEB J. 2017 Jan;31(1):388-399. doi: 10.1096/fj.201600926R. Epub 2016 Oct 12.

7.

Update on melatonin receptors: IUPHAR Review 20.

Jockers R, Delagrange P, Dubocovich ML, Markus RP, Renault N, Tosini G, Cecon E, Zlotos DP.

Br J Pharmacol. 2016 Sep;173(18):2702-25. doi: 10.1111/bph.13536. Epub 2016 Aug 8. Review.

8.

Melatonin receptor activation increases glutamatergic synaptic transmission in the rat medial lateral habenula.

Evely KM, Hudson RL, Dubocovich ML, Haj-Dahmane S.

Synapse. 2016 May;70(5):181-6. doi: 10.1002/syn.21892. Epub 2016 Feb 22.

PMID:
26799638
9.

MT1 and MT2 Melatonin Receptors: A Therapeutic Perspective.

Liu J, Clough SJ, Hutchinson AJ, Adamah-Biassi EB, Popovska-Gorevski M, Dubocovich ML.

Annu Rev Pharmacol Toxicol. 2016;56:361-83. doi: 10.1146/annurev-pharmtox-010814-124742. Epub 2015 Oct 23. Review.

10.

Genetic deletion of MT1 melatonin receptors alters spontaneous behavioral rhythms in male and female C57BL/6 mice.

Adamah-Biassi EB, Hudson RL, Dubocovich ML.

Horm Behav. 2014 Sep;66(4):619-27. doi: 10.1016/j.yhbeh.2014.08.012. Epub 2014 Sep 6.

11.

Genetic deletion of the MT1 or MT2 melatonin receptors abrogates methamphetamine-induced reward in C3H/HeN mice.

Clough SJ, Hutchinson AJ, Hudson RL, Dubocovich ML.

Physiol Behav. 2014 Jun 10;132:79-86. doi: 10.1016/j.physbeh.2014.04.049. Epub 2014 May 9.

12.

The Concise Guide to PHARMACOLOGY 2013/14: overview.

Alexander SP, Benson HE, Faccenda E, Pawson AJ, Sharman JL, McGrath JC, Catterall WA, Spedding M, Peters JA, Harmar AJ; CGTP Collaborators, Abul-Hasn N, Anderson CM, Anderson CM, Araiksinen MS, Arita M, Arthofer E, Barker EL, Barratt C, Barnes NM, Bathgate R, Beart PM, Belelli D, Bennett AJ, Birdsall NJ, Boison D, Bonner TI, Brailsford L, Bröer S, Brown P, Calo G, Carter WG, Catterall WA, Chan SL, Chao MV, Chiang N, Christopoulos A, Chun JJ, Cidlowski J, Clapham DE, Cockcroft S, Connor MA, Cox HM, Cuthbert A, Dautzenberg FM, Davenport AP, Dawson PA, Dent G, Dijksterhuis JP, Dollery CT, Dolphin AC, Donowitz M, Dubocovich ML, Eiden L, Eidne K, Evans BA, Fabbro D, Fahlke C, Farndale R, Fitzgerald GA, Fong TM, Fowler CJ, Fry JR, Funk CD, Futerman AH, Ganapathy V, Gaisnier B, Gershengorn MA, Goldin A, Goldman ID, Gundlach AL, Hagenbuch B, Hales TG, Hammond JR, Hamon M, Hancox JC, Hauger RL, Hay DL, Hobbs AJ, Hollenberg MD, Holliday ND, Hoyer D, Hynes NA, Inui KI, Ishii S, Jacobson KA, Jarvis GE, Jarvis MF, Jensen R, Jones CE, Jones RL, Kaibuchi K, Kanai Y, Kennedy C, Kerr ID, Khan AA, Klienz MJ, Kukkonen JP, Lapoint JY, Leurs R, Lingueglia E, Lippiat J, Lolait SJ, Lummis SC, Lynch JW, MacEwan D, Maguire JJ, Marshall IL, May JM, McArdle CA, McGrath JC, Michel MC, Millar NS, Miller LJ, Mitolo V, Monk PN, Moore PK, Moorhouse AJ, Mouillac B, Murphy PM, Neubig RR, Neumaier J, Niesler B, Obaidat A, Offermanns S, Ohlstein E, Panaro MA, Parsons S, Pwrtwee RG, Petersen J, Pin JP, Poyner DR, Prigent S, Prossnitz ER, Pyne NJ, Pyne S, Quigley JG, Ramachandran R, Richelson EL, Roberts RE, Roskoski R, Ross RA, Roth M, Rudnick G, Ryan RM, Said SI, Schild L, Sanger GJ, Scholich K, Schousboe A, Schulte G, Schulz S, Serhan CN, Sexton PM, Sibley DR, Siegel JM, Singh G, Sitsapesan R, Smart TG, Smith DM, Soga T, Stahl A, Stewart G, Stoddart LA, Summers RJ, Thorens B, Thwaites DT, Toll L, Traynor JR, Usdin TB, Vandenberg RJ, Villalon C, Vore M, Waldman SA, Ward DT, Willars GB, Wonnacott SJ, Wright E, Ye RD, Yonezawa A, Zimmermann M.

Br J Pharmacol. 2013 Dec;170(8):1449-58. doi: 10.1111/bph.12444.

13.

Long-term effects of maternal separation on the responsiveness of the circadian system to melatonin in the diurnal nonhuman primate (Macaca mulatta).

Rawashdeh O, Dubocovich ML.

J Pineal Res. 2014 Apr;56(3):254-63. doi: 10.1111/jpi.12118. Epub 2014 Feb 19.

14.

Distribution of MT1 melatonin receptor promoter-driven RFP expression in the brains of BAC C3H/HeN transgenic mice.

Adamah-Biassi EB, Zhang Y, Jung H, Vissapragada S, Miller RJ, Dubocovich Ml.

J Histochem Cytochem. 2014 Jan;62(1):70-84. doi: 10.1369/0022155413507453. Epub 2013 Sep 18.

15.

Role of MT1 melatonin receptors in methamphetamine-induced locomotor sensitization in C57BL/6 mice.

Hutchinson AJ, Ma J, Liu J, Hudson RL, Dubocovich ML.

Psychopharmacology (Berl). 2014 Jan;231(1):257-67. doi: 10.1007/s00213-013-3228-0. Epub 2013 Aug 11.

16.

Automated video analysis system reveals distinct diurnal behaviors in C57BL/6 and C3H/HeN mice.

Adamah-Biassi EB, Stepien I, Hudson RL, Dubocovich ML.

Behav Brain Res. 2013 Apr 15;243:306-12. doi: 10.1016/j.bbr.2013.01.003. Epub 2013 Jan 18.

17.

Melatonin potentiates running wheel-induced neurogenesis in the dentate gyrus of adult C3H/HeN mice hippocampus.

Liu J, Somera-Molina KC, Hudson RL, Dubocovich ML.

J Pineal Res. 2013 Mar;54(2):222-31. doi: 10.1111/jpi.12023. Epub 2012 Nov 28.

18.
19.

Circadian periods of sensitivity for ramelteon on the onset of running-wheel activity and the peak of suprachiasmatic nucleus neuronal firing rhythms in C3H/HeN mice.

Rawashdeh O, Hudson RL, Stepien I, Dubocovich ML.

Chronobiol Int. 2011 Feb;28(1):31-8. doi: 10.3109/07420528.2010.532894.

20.

International Union of Basic and Clinical Pharmacology. LXXV. Nomenclature, classification, and pharmacology of G protein-coupled melatonin receptors.

Dubocovich ML, Delagrange P, Krause DN, Sugden D, Cardinali DP, Olcese J.

Pharmacol Rev. 2010 Sep;62(3):343-80. doi: 10.1124/pr.110.002832. Epub 2010 Jul 6.

21.

Melatonin receptors: role on sleep and circadian rhythm regulation.

Dubocovich ML.

Sleep Med. 2007 Dec;8 Suppl 3:34-42. Review.

PMID:
18032103
22.

Behavioral characterization and modulation of circadian rhythms by light and melatonin in C3H/HeN mice homozygous for the RORbeta knockout.

Masana MI, Sumaya IC, Becker-Andre M, Dubocovich ML.

Am J Physiol Regul Integr Comp Physiol. 2007 Jun;292(6):R2357-67. Epub 2007 Feb 15.

23.

Agomelatine targets a range of major depressive disorder symptoms.

Dubocovich ML.

Curr Opin Investig Drugs. 2006 Jul;7(7):670-80. Review.

PMID:
16869122
24.

Melatonin-depleted blood from premenopausal women exposed to light at night stimulates growth of human breast cancer xenografts in nude rats.

Blask DE, Brainard GC, Dauchy RT, Hanifin JP, Davidson LK, Krause JA, Sauer LA, Rivera-Bermudez MA, Dubocovich ML, Jasser SA, Lynch DT, Rollag MD, Zalatan F.

Cancer Res. 2005 Dec 1;65(23):11174-84.

25.

Phase-dependent treatment of delayed sleep phase syndrome with melatonin.

Mundey K, Benloucif S, Harsanyi K, Dubocovich ML, Zee PC.

Sleep. 2005 Oct;28(10):1271-8.

PMID:
16295212
26.

Functional MT1 and MT2 melatonin receptors in mammals.

Dubocovich ML, Markowska M.

Endocrine. 2005 Jul;27(2):101-10. Review.

PMID:
16217123
28.

Effect of MT1 melatonin receptor deletion on melatonin-mediated phase shift of circadian rhythms in the C57BL/6 mouse.

Dubocovich ML, Hudson RL, Sumaya IC, Masana MI, Manna E.

J Pineal Res. 2005 Sep;39(2):113-20.

PMID:
16098087
29.

The impact of school daily schedule on adolescent sleep.

Hansen M, Janssen I, Schiff A, Zee PC, Dubocovich ML.

Pediatrics. 2005 Jun;115(6):1555-61.

PMID:
15930216
30.

17Beta-estradiol modulates hMT1 melatonin receptor function.

Masana MI, Soares JM Jr, Dubocovich ML.

Neuroendocrinology. 2005;81(2):87-95. Epub 2005 Apr 4.

PMID:
15809517
31.

Melatonin desensitizes endogenous MT2 melatonin receptors in the rat suprachiasmatic nucleus: relevance for defining the periods of sensitivity of the mammalian circadian clock to melatonin.

Gerdin MJ, Masana MI, Rivera-Bermúdez MA, Hudson RL, Earnest DJ, Gillette MU, Dubocovich ML.

FASEB J. 2004 Nov;18(14):1646-56.

PMID:
15522910
32.

Key MT2 melatonin receptor citation still buried - dig deeper!

Gerdin MJ, Dubocovich ML.

J Pineal Res. 2004 Sep;37(2):142; author reply 142. No abstract available.

PMID:
15298674
33.

Melatonin-mediated regulation of human MT(1) melatonin receptors expressed in mammalian cells.

Gerdin MJ, Masana MI, Dubocovich ML.

Biochem Pharmacol. 2004 Jun 1;67(11):2023-30.

PMID:
15135299
34.

Immortalized cells from the rat suprachiasmatic nucleus express functional melatonin receptors.

Rivera-Bermúdez MA, Masana MI, Brown GM, Earnest DJ, Dubocovich ML.

Brain Res. 2004 Mar 26;1002(1-2):21-7.

PMID:
14988029
35.

Molecular pharmacology, regulation and function of mammalian melatonin receptors.

Dubocovich ML, Rivera-Bermudez MA, Gerdin MJ, Masana MI.

Front Biosci. 2003 Sep 1;8:d1093-108. Review.

PMID:
12957828
36.

Regulation of basal rhythmicity in protein kinase C activity by melatonin in immortalized rat suprachiasmatic nucleus cells.

Rivera-Bermúdez MA, Gerdin MJ, Earnest DJ, Dubocovich ML.

Neurosci Lett. 2003 Jul 31;346(1-2):37-40.

PMID:
12850542
37.

Mutagenesis studies of the human MT2 melatonin receptor.

Gerdin MJ, Mseeh F, Dubocovich ML.

Biochem Pharmacol. 2003 Jul 15;66(2):315-20.

PMID:
12826274
38.

Functional melatonin receptors in rat ovaries at various stages of the estrous cycle.

Soares JM Jr, Masana MI, Erşahin C, Dubocovich ML.

J Pharmacol Exp Ther. 2003 Aug;306(2):694-702. Epub 2003 Apr 29.

PMID:
12721330
39.
40.

Melatonin differentially modulates the expression and function of the hMT1 and hMT2 melatonin receptors upon prolonged withdrawal.

Masana MI, Witt-Enderby PA, Dubocovich ML.

Biochem Pharmacol. 2003 Mar 1;65(5):731-9.

PMID:
12628486
41.

Short-term exposure to melatonin differentially affects the functional sensitivity and trafficking of the hMT1 and hMT2 melatonin receptors.

Gerdin MJ, Masana MI, Ren D, Miller RJ, Dubocovich ML.

J Pharmacol Exp Ther. 2003 Mar;304(3):931-9.

PMID:
12604667
42.

MT(2) melatonin receptors are present and functional in rat caudal artery.

Masana MI, Doolen S, Ersahin C, Al-Ghoul WM, Duckles SP, Dubocovich ML, Krause DN.

J Pharmacol Exp Ther. 2002 Sep;302(3):1295-302.

PMID:
12183692
43.

MT(1) melatonin receptor overexpression enhances the growth suppressive effect of melatonin in human breast cancer cells.

Yuan L, Collins AR, Dai J, Dubocovich ML, Hill SM.

Mol Cell Endocrinol. 2002 Jun 28;192(1-2):147-56.

PMID:
12088876
44.

Constitutively active melatonin MT(1) receptors in male rat caudal arteries.

Erşahin C, Masana MI, Dubocovich ML.

Eur J Pharmacol. 2002 Mar 29;439(1-3):171-2.

PMID:
11937107
45.

Melatonin and N-acetylserotonin inhibit leukocyte rolling and adhesion to rat microcirculation.

Lotufo CM, Lopes C, Dubocovich ML, Farsky SH, Markus RP.

Eur J Pharmacol. 2001 Nov 2;430(2-3):351-7.

PMID:
11711054
46.

Melatonin receptor signaling: finding the path through the dark.

Masana MI, Dubocovich ML.

Sci STKE. 2001 Nov 6;2001(107):pe39. Review.

PMID:
11698691
47.

Familial advanced sleep phase syndrome.

Reid KJ, Chang AM, Dubocovich ML, Turek FW, Takahashi JS, Zee PC.

Arch Neurol. 2001 Jul;58(7):1089-94.

PMID:
11448298
48.

Activation of MT(2) melatonin receptors in rat suprachiasmatic nucleus phase advances the circadian clock.

Hunt AE, Al-Ghoul WM, Gillette MU, Dubocovich ML.

Am J Physiol Cell Physiol. 2001 Jan;280(1):C110-8.

49.

Molecular pharmacology and function of melatonin receptor subtypes.

Dubocovich ML, Masana MI, Benloucif S.

Adv Exp Med Biol. 1999;460:181-90. Review. No abstract available.

PMID:
10810513
50.

Circadian rhythm of mt1 melatonin receptor expression in the suprachiasmatic nucleus of the C3H/HeN mouse.

Masana MI, Benloucif S, Dubocovich ML.

J Pineal Res. 2000 Apr;28(3):185-92.

PMID:
10739306

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