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Items: 1 to 50 of 111

1.

On the Development of Electron Cryo-Microscopy (Nobel Lecture).

Dubochet J.

Angew Chem Int Ed Engl. 2018 Aug 20;57(34):10842-10846. doi: 10.1002/anie.201804280. Epub 2018 Jul 9. Review.

PMID:
29984876
2.

Ups and downs in early electron cryo-microscopy.

Dubochet J, Knapek E.

PLoS Biol. 2018 Apr 19;16(4):e2005550. doi: 10.1371/journal.pbio.2005550. eCollection 2018 Apr.

3.

A Reminiscence about Early Times of Vitreous Water in Electron Cryomicroscopy.

Dubochet J.

Biophys J. 2016 Feb 23;110(4):756-7. doi: 10.1016/j.bpj.2015.07.049. Epub 2015 Sep 8. Review. No abstract available.

4.

Cryo-EM--the first thirty years.

Dubochet J.

J Microsc. 2012 Mar;245(3):221-4. Review.

PMID:
22457877
5.
6.

Comparison of different methods for thin section EM analysis of Mycobacterium smegmatis.

Bleck CK, Merz A, Gutierrez MG, Walther P, Dubochet J, Zuber B, Griffiths G.

J Microsc. 2010 Jan;237(1):23-38. doi: 10.1111/j.1365-2818.2009.03299.x.

7.

Genomics for citizens. Providing the public with more and better knowledge to address the challenges of the twenty-first century.

Dubochet J.

EMBO Rep. 2009 Oct;10(10):1076-9. doi: 10.1038/embor.2009.209. Epub 2009 Sep 18. No abstract available.

8.

Aggregation behavior of poly(ethylene glycol-bl-propylene sulfide) di- and triblock copolymers in aqueous solution.

Cerritelli S, O'Neil CP, Velluto D, Fontana A, Adrian M, Dubochet J, Hubbell JA.

Langmuir. 2009 Oct 6;25(19):11328-35. doi: 10.1021/la900649m.

PMID:
19711914
9.

Extracellular matrix binding mixed micelles for drug delivery applications.

O'Neil CP, van der Vlies AJ, Velluto D, Wandrey C, Demurtas D, Dubochet J, Hubbell JA.

J Control Release. 2009 Jul 20;137(2):146-51. doi: 10.1016/j.jconrel.2009.03.013. Epub 2009 Mar 27.

PMID:
19332089
10.

Bending modes of DNA directly addressed by cryo-electron microscopy of DNA minicircles.

Demurtas D, Amzallag A, Rawdon EJ, Maddocks JH, Dubochet J, Stasiak A.

Nucleic Acids Res. 2009 May;37(9):2882-93. doi: 10.1093/nar/gkp137. Epub 2009 Mar 12.

11.

Analysis of cryo-electron microscopy images does not support the existence of 30-nm chromatin fibers in mitotic chromosomes in situ.

Eltsov M, Maclellan KM, Maeshima K, Frangakis AS, Dubochet J.

Proc Natl Acad Sci U S A. 2008 Dec 16;105(50):19732-7. doi: 10.1073/pnas.0810057105. Epub 2008 Dec 8.

12.

Direct visualization of the outer membrane of mycobacteria and corynebacteria in their native state.

Zuber B, Chami M, Houssin C, Dubochet J, Griffiths G, Daffé M.

J Bacteriol. 2008 Aug;190(16):5672-80. doi: 10.1128/JB.01919-07. Epub 2008 Jun 20.

13.

Compression and crevasses in vitreous sections under different cutting conditions.

Han HM, Zuber B, Dubochet J.

J Microsc. 2008 May;230(Pt 2):167-71. doi: 10.1111/j.1365-2818.2008.01972.x.

14.

Citizen biologists. The Lausanne experience.

Dubochet J.

EMBO Rep. 2008 Jan;9(1):5-9. doi: 10.1038/sj.embor.7401146. No abstract available.

15.

How to "read" a vitreous section.

Dubochet J, Zuber B, Eltsov M, Bouchet-Marquis C, Al-Amoudi A, Livolant F.

Methods Cell Biol. 2007;79:385-406. No abstract available.

PMID:
17327166
16.

The physics of rapid cooling and its implications for cryoimmobilization of cells.

Dubochet J.

Methods Cell Biol. 2007;79:7-21. No abstract available.

PMID:
17327150
17.

Visualization of cell microtubules in their native state.

Bouchet-Marquis C, Zuber B, Glynn AM, Eltsov M, Grabenbauer M, Goldie KN, Thomas D, Frangakis AS, Dubochet J, Chrétien D.

Biol Cell. 2007 Jan;99(1):45-53.

PMID:
17049046
18.

3D reconstruction and comparison of shapes of DNA minicircles observed by cryo-electron microscopy.

Amzallag A, Vaillant C, Jacob M, Unser M, Bednar J, Kahn JD, Dubochet J, Stasiak A, Maddocks JH.

Nucleic Acids Res. 2006;34(18):e125. Epub 2006 Sep 29.

19.

Luminal particles within cellular microtubules.

Garvalov BK, Zuber B, Bouchet-Marquis C, Kudryashev M, Gruska M, Beck M, Leis A, Frischknecht F, Bradke F, Baumeister W, Dubochet J, Cyrklaff M.

J Cell Biol. 2006 Sep 11;174(6):759-65. Epub 2006 Sep 5.

21.

Study of the Deinococcus radiodurans nucleoid by cryoelectron microscopy of vitreous sections: Supplementary comments.

Eltsov M, Dubochet J.

J Bacteriol. 2006 Sep;188(17):6053-8; discussion 6059. No abstract available.

22.

Multifunctional lipid/quantum dot hybrid nanocontainers for controlled targeting of live cells.

Gopalakrishnan G, Danelon C, Izewska P, Prummer M, Bolinger PY, Geissbühler I, Demurtas D, Dubochet J, Vogel H.

Angew Chem Int Ed Engl. 2006 Aug 18;45(33):5478-83. No abstract available.

PMID:
16847983
23.

Scaling behavior of random knots.

Dobay A, Dubochet J, Millett K, Sottas PE, Stasiak A.

Proc Natl Acad Sci U S A. 2003 May 13;100(10):5611-5. Epub 2003 Apr 29.

24.

The mammalian central nervous synaptic cleft contains a high density of periodically organized complexes.

Zuber B, Nikonenko I, Klauser P, Muller D, Dubochet J.

Proc Natl Acad Sci U S A. 2005 Dec 27;102(52):19192-7. Epub 2005 Dec 14.

25.

Cryoelectron microscopy of vitrified sections: a new challenge for the analysis of functional nuclear architecture.

Bouchet-Marquis C, Dubochet J, Fakan S.

Histochem Cell Biol. 2006 Jan;125(1-2):43-51. Epub 2005 Dec 13.

PMID:
16328430
26.
27.

High resolution structural analysis of Helicobacter pylori VacA toxin oligomers by cryo-negative staining electron microscopy.

El-Bez C, Adrian M, Dubochet J, Cover TL.

J Struct Biol. 2005 Sep;151(3):215-28.

PMID:
16125415
28.
29.

Cutting artefacts and cutting process in vitreous sections for cryo-electron microscopy.

Al-Amoudi A, Studer D, Dubochet J.

J Struct Biol. 2005 Apr;150(1):109-21.

PMID:
15797735
30.

Obituary: Eduard Kellenberger (1920-2004).

Strasser BJ, Dubochet J.

Nature. 2005 Feb 24;433(7028):817. No abstract available.

PMID:
15729328
31.

Cryo-electron microscopy of vitreous sections of native biological cells and tissues.

Al-Amoudi A, Norlen LP, Dubochet J.

J Struct Biol. 2004 Oct;148(1):131-5.

PMID:
15363793
32.

Cryo-electron microscopy of vitreous sections.

Al-Amoudi A, Chang JJ, Leforestier A, McDowall A, Salamin LM, Norlén LP, Richter K, Blanc NS, Studer D, Dubochet J.

EMBO J. 2004 Sep 15;23(18):3583-8. Epub 2004 Aug 19. Review.

33.

Role of LBPA and Alix in multivesicular liposome formation and endosome organization.

Matsuo H, Chevallier J, Mayran N, Le Blanc I, Ferguson C, Fauré J, Blanc NS, Matile S, Dubochet J, Sadoul R, Parton RG, Vilbois F, Gruenberg J.

Science. 2004 Jan 23;303(5657):531-4.

34.

Cryo-transmission electron microscopy of frozen-hydrated sections of Escherichia coli and Pseudomonas aeruginosa.

Matias VR, Al-Amoudi A, Dubochet J, Beveridge TJ.

J Bacteriol. 2003 Oct;185(20):6112-8.

35.

An oscillating cryo-knife reduces cutting-induced deformation of vitreous ultrathin sections.

Al-Amoudi A, Dubochet J, Gnaegi H, Lüthi W, Studer D.

J Microsc. 2003 Oct;212(Pt 1):26-33.

36.
37.

A cryotransmission electron microscopy study of skin barrier formation.

Norlén L, Al-Amoudi A, Dubochet J.

J Invest Dermatol. 2003 Apr;120(4):555-60.

38.

Conversion of a transmembrane to a water-soluble protein complex by a single point mutation.

Tsitrin Y, Morton CJ, el-Bez C, Paumard P, Velluz MC, Adrian M, Dubochet J, Parker MW, Lanzavecchia S, van der Goot FG.

Nat Struct Biol. 2002 Oct;9(10):729-33.

PMID:
12219082
39.

Cryo-negative staining reduces electron-beam sensitivity of vitrified biological particles.

De Carlo S, El-Bez C, Alvarez-Rúa C, Borge J, Dubochet J.

J Struct Biol. 2002 Jun;138(3):216-26.

PMID:
12217660
40.

Amorphous solid water produced by cryosectioning of crystalline ice at 113 K.

AL-Amoudi A, Dubochet J, Studer D.

J Microsc. 2002 Aug;207(Pt 2):146-53.

41.

Multiple oligomeric states of the Helicobacter pylori vacuolating toxin demonstrated by cryo-electron microscopy.

Adrian M, Cover TL, Dubochet J, Heuser JE.

J Mol Biol. 2002 Apr 19;318(1):121-33.

PMID:
12054773
42.

Bilayers of nucleosome core particles.

Leforestier A, Dubochet J, Livolant F.

Biophys J. 2001 Oct;81(4):2414-21.

43.

DNA in human and stallion spermatozoa forms local hexagonal packing with twist and many defects.

Sartori Blanc N, Senn A, Leforestier A, Livolant F, Dubochet J.

J Struct Biol. 2001 Apr;134(1):76-81.

PMID:
11469879
44.

Tightness of random knotting.

Katritch V, Olson WK, Vologodskii A, Dubochet J, Stasiak A.

Phys Rev E Stat Phys Plasmas Fluids Relat Interdiscip Topics. 2000 May;61(5 Pt B):5545-9.

PMID:
11031608
45.

Self-assembly of beta-amyloid 42 is retarded by small molecular ligands at the stage of structural intermediates.

Bohrmann B, Adrian M, Dubochet J, Kuner P, Müller F, Huber W, Nordstedt C, Döbeli H.

J Struct Biol. 2000 Jun;130(2-3):232-46.

PMID:
10940228
46.

The cell in absence of aggregation artifacts.

Dubochet J, Sartori Blanc N.

Micron. 2001 Jan;32(1):91-9.

PMID:
10900384
47.

Making science in a fractal landscape.

Dubochet J.

Micron. 2001 Jan;32(1):7-9.

PMID:
10900375
48.

Unexpected property of trehalose as observed by cryo-electron microscopy.

De Carlo S, Adrian M, Kälin P, Mayer JM, Dubochet J.

J Microsc. 1999 Oct;196(1):40-45.

49.

Brownian dynamics simulation of DNA condensation.

Sottas PE, Larquet E, Stasiak A, Dubochet J.

Biophys J. 1999 Oct;77(4):1858-70.

50.

DNA: uncooked, al dente, or scotti?

Stasiak A, Dubochet J, Furrer P, Gonzalez O, Maddocks J.

Science. 1999 Mar 12;283(5408):1641. No abstract available.

PMID:
10189314

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