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Items: 21


Structural Basis of Leader Peptide Recognition in Lasso Peptide Biosynthesis Pathway.

Sumida T, Dubiley S, Wilcox B, Severinov K, Tagami S.

ACS Chem Biol. 2019 Jul 19;14(7):1619-1627. doi: 10.1021/acschembio.9b00348. Epub 2019 Jun 24.


Reiterative Synthesis by the Ribosome and Recognition of the N-Terminal Formyl Group by Biosynthetic Machinery Contribute to Evolutionary Conservation of the Length of Antibiotic Microcin C Peptide Precursor.

Zukher I, Pavlov M, Tsibulskaya D, Kulikovsky A, Zyubko T, Bikmetov D, Serebryakova M, Nair SK, Ehrenberg M, Dubiley S, Severinov K.

mBio. 2019 Apr 30;10(2). pii: e00768-19. doi: 10.1128/mBio.00768-19.


Biosynthesis of the RiPP trojan horse nucleotide antibiotic microcin C is directed by the N-formyl of the peptide precursor.

Dong SH, Kulikovsky A, Zukher I, Estrada P, Dubiley S, Severinov K, Nair SK.

Chem Sci. 2018 Dec 26;10(8):2391-2395. doi: 10.1039/c8sc03173h. eCollection 2019 Feb 28.


Ultrahigh-throughput functional profiling of microbiota communities.

Terekhov SS, Smirnov IV, Malakhova MV, Samoilov AE, Manolov AI, Nazarov AS, Danilov DV, Dubiley SA, Osterman IA, Rubtsova MP, Kostryukova ES, Ziganshin RH, Kornienko MA, Vanyushkina AA, Bukato ON, Ilina EN, Vlasov VV, Severinov KV, Gabibov AG, Altman S.

Proc Natl Acad Sci U S A. 2018 Sep 18;115(38):9551-9556. doi: 10.1073/pnas.1811250115. Epub 2018 Sep 4.


Escherichia coli ItaT is a type II toxin that inhibits translation by acetylating isoleucyl-tRNAIle.

Wilcox B, Osterman I, Serebryakova M, Lukyanov D, Komarova E, Gollan B, Morozova N, Wolf YI, Makarova KS, Helaine S, Sergiev P, Dubiley S, Borukhov S, Severinov K.

Nucleic Acids Res. 2018 Sep 6;46(15):7873-7885. doi: 10.1093/nar/gky560.


The Product of Yersinia pseudotuberculosis mcc Operon Is a Peptide-Cytidine Antibiotic Activated Inside Producing Cells by the TldD/E Protease.

Tsibulskaya D, Mokina O, Kulikovsky A, Piskunova J, Severinov K, Serebryakova M, Dubiley S.

J Am Chem Soc. 2017 Nov 15;139(45):16178-16187. doi: 10.1021/jacs.7b07118. Epub 2017 Oct 31.


A Trojan-Horse Peptide-Carboxymethyl-Cytidine Antibiotic from Bacillus amyloliquefaciens.

Serebryakova M, Tsibulskaya D, Mokina O, Kulikovsky A, Nautiyal M, Van Aerschot A, Severinov K, Dubiley S.

J Am Chem Soc. 2016 Dec 7;138(48):15690-15698. Epub 2016 Nov 29.


Enzymatic Synthesis and Functional Characterization of Bioactive Microcin C-Like Compounds with Altered Peptide Sequence and Length.

Bantysh O, Serebryakova M, Zukher I, Kulikovsky A, Tsibulskaya D, Dubiley S, Severinov K.

J Bacteriol. 2015 Oct;197(19):3133-41. doi: 10.1128/JB.00271-15. Epub 2015 Jul 20.


The Pseudomonas aeruginosa PA14 ABC Transporter NppA1A2BCD Is Required for Uptake of Peptidyl Nucleoside Antibiotics.

Pletzer D, Braun Y, Dubiley S, Lafon C, Köhler T, Page MGP, Mourez M, Severinov K, Weingart H.

J Bacteriol. 2015 Jul;197(13):2217-2228. doi: 10.1128/JB.00234-15. Epub 2015 Apr 27.


The molecular mechanism of aminopropylation of peptide-nucleotide antibiotic microcin C.

Kulikovsky A, Serebryakova M, Bantysh O, Metlitskaya A, Borukhov S, Severinov K, Dubiley S.

J Am Chem Soc. 2014 Aug 6;136(31):11168-75. doi: 10.1021/ja505982c. Epub 2014 Jul 23.


Enzymatic synthesis of bioinformatically predicted microcin C-like compounds encoded by diverse bacteria.

Bantysh O, Serebryakova M, Makarova KS, Dubiley S, Datsenko KA, Severinov K.

mBio. 2014 May 6;5(3):e01059-14. doi: 10.1128/mBio.01059-14.


Extended targeting potential and improved synthesis of Microcin C analogs as antibacterials.

Vondenhoff GH, Dubiley S, Severinov K, Lescrinier E, Rozenski J, Van Aerschot A.

Bioorg Med Chem. 2011 Sep 15;19(18):5462-7. doi: 10.1016/j.bmc.2011.07.052. Epub 2011 Aug 3.


Molecular epidemiology of tuberculosis in the Tula area, Central Russia, before the introduction of the Directly Observed Therapy Strategy.

Dubiley S, Ignatova A, Mukhina T, Nizova A, Blagodatskikh S, Stepanshina V, Shemyakin I.

Clin Microbiol Infect. 2010 Sep;16(9):1421-6. doi: 10.1111/j.1469-0691.2009.03102.x.


Substrate recognition of anthrax lethal factor examined by combinatorial and pre-steady-state kinetic approaches.

Zakharova MY, Kuznetsov NA, Dubiley SA, Kozyr AV, Fedorova OS, Chudakov DM, Knorre DG, Shemyakin IG, Gabibov AG, Kolesnikov AV.

J Biol Chem. 2009 Jul 3;284(27):17902-13. doi: 10.1074/jbc.M807510200. Epub 2009 Apr 9.


Substrate specificity of the anthrax lethal factor.

Zakharova MY, Dubiley SA, Chudakov DM, Gabibov AG, Shemyakin IG, Kolesnikov AV.

Dokl Biochem Biophys. 2008 Jan-Feb;418:14-7. No abstract available.


Molecular characteristics of the Mycobacterium tuberculosis LAM-RUS family prevalent in Central Russia.

Dubiley S, Kirillov E, Ignatova A, Stepanshina V, Shemyakin I.

J Clin Microbiol. 2007 Dec;45(12):4036-8. Epub 2007 Oct 17.


New PCR-based assay for detection of common mutations associated with rifampin and isoniazid resistance in Mycobacterium tuberculosis.

Dubiley S, Mayorova A, Ignatova A, Kirillov E, Stepanshina V, Kolesnikov A, Shemyakin I.

Clin Chem. 2005 Feb;51(2):447-50. No abstract available.


Polymorphism analysis and gene detection by minisequencing on an array of gel-immobilized primers.

Dubiley S, Kirillov E, Mirzabekov A.

Nucleic Acids Res. 1999 Sep 15;27(18):e19.


Fractionation, phosphorylation and ligation on oligonucleotide microchips to enhance sequencing by hybridization.

Dubiley S, Kirillov E, Lysov Y, Mirzabekov A.

Nucleic Acids Res. 1997 Jun 15;25(12):2259-65.


DNA analysis and diagnostics on oligonucleotide microchips.

Yershov G, Barsky V, Belgovskiy A, Kirillov E, Kreindlin E, Ivanov I, Parinov S, Guschin D, Drobishev A, Dubiley S, Mirzabekov A.

Proc Natl Acad Sci U S A. 1996 May 14;93(10):4913-8.

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