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Items: 17


Deep mutational scanning of an antibody against epidermal growth factor receptor using mammalian cell display and massively parallel pyrosequencing.

Forsyth CM, Juan V, Akamatsu Y, DuBridge RB, Doan M, Ivanov AV, Ma Z, Polakoff D, Razo J, Wilson K, Powers DB.

MAbs. 2013 Jul-Aug;5(4):523-32. doi: 10.4161/mabs.24979. Epub 2013 May 29.


Affinity and cross-reactivity engineering of CTLA4-Ig to modulate T cell costimulation.

Xu Z, Juan V, Ivanov A, Ma Z, Polakoff D, Powers DB, Dubridge RB, Wilson K, Akamatsu Y.

J Immunol. 2012 Nov 1;189(9):4470-7. doi: 10.4049/jimmunol.1201813. Epub 2012 Sep 26.


The immunogenicity of humanized and fully human antibodies: residual immunogenicity resides in the CDR regions.

Harding FA, Stickler MM, Razo J, DuBridge RB.

MAbs. 2010 May-Jun;2(3):256-65. Epub 2010 May 1.


A function blocking anti-mouse integrin alpha5beta1 antibody inhibits angiogenesis and impedes tumor growth in vivo.

Bhaskar V, Zhang D, Fox M, Seto P, Wong MH, Wales PE, Powers D, Chao DT, Dubridge RB, Ramakrishnan V.

J Transl Med. 2007 Nov 27;5:61.


Volociximab, a chimeric integrin alpha5beta1 antibody, inhibits the growth of VX2 tumors in rabbits.

Bhaskar V, Fox M, Breinberg D, Wong MH, Wales PE, Rhodes S, DuBridge RB, Ramakrishnan V.

Invest New Drugs. 2008 Feb;26(1):7-12. Epub 2007 Sep 1.


Preclinical evaluation of an anti-alpha5beta1 integrin antibody as a novel anti-angiogenic agent.

Ramakrishnan V, Bhaskar V, Law DA, Wong MH, DuBridge RB, Breinberg D, O'Hara C, Powers DB, Liu G, Grove J, Hevezi P, Cass KM, Watson S, Evangelista F, Powers RA, Finck B, Wills M, Caras I, Fang Y, McDonald D, Johnson D, Murray R, Jeffry U.

J Exp Ther Oncol. 2006;5(4):273-86.


Preclinical validation of anti-TMEFF2-auristatin E-conjugated antibodies in the treatment of prostate cancer.

Afar DE, Bhaskar V, Ibsen E, Breinberg D, Henshall SM, Kench JG, Drobnjak M, Powers R, Wong M, Evangelista F, O'Hara C, Powers D, DuBridge RB, Caras I, Winter R, Anderson T, Solvason N, Stricker PD, Cordon-Cardo C, Scher HI, Grygiel JJ, Sutherland RL, Murray R, Ramakrishnan V, Law DA.

Mol Cancer Ther. 2004 Aug;3(8):921-32.


E-selectin up-regulation allows for targeted drug delivery in prostate cancer.

Bhaskar V, Law DA, Ibsen E, Breinberg D, Cass KM, DuBridge RB, Evangelista F, Henshall SM, Hevezi P, Miller JC, Pong M, Powers R, Senter P, Stockett D, Sutherland RL, von Freeden-Jeffry U, Willhite D, Murray R, Afar DE, Ramakrishnan V.

Cancer Res. 2003 Oct 1;63(19):6387-94.


Gene expression analysis by massively parallel signature sequencing (MPSS) on microbead arrays.

Brenner S, Johnson M, Bridgham J, Golda G, Lloyd DH, Johnson D, Luo S, McCurdy S, Foy M, Ewan M, Roth R, George D, Eletr S, Albrecht G, Vermaas E, Williams SR, Moon K, Burcham T, Pallas M, DuBridge RB, Kirchner J, Fearon K, Mao J, Corcoran K.

Nat Biotechnol. 2000 Jun;18(6):630-4. Erratum in: Nat Biotechnol 2000 Oct;18(10):1021.


In vitro cloning of complex mixtures of DNA on microbeads: physical separation of differentially expressed cDNAs.

Brenner S, Williams SR, Vermaas EH, Storck T, Moon K, McCollum C, Mao JI, Luo S, Kirchner JJ, Eletr S, DuBridge RB, Burcham T, Albrecht G.

Proc Natl Acad Sci U S A. 2000 Feb 15;97(4):1665-70.


Increased thrombin responsiveness in platelets from mice lacking glycoprotein V.

Ramakrishnan V, Reeves PS, DeGuzman F, Deshpande U, Ministri-Madrid K, DuBridge RB, Phillips DR.

Proc Natl Acad Sci U S A. 1999 Nov 9;96(23):13336-41.


Rapid detection of homologous recombinants in nontransformed human cells.

Williams SR, Ousley FC, Vitez LJ, DuBridge RB.

Proc Natl Acad Sci U S A. 1994 Dec 6;91(25):11943-7.


Use of simian virus 40 replication to amplify Epstein-Barr virus shuttle vectors in human cells.

Heinzel SS, Krysan PJ, Calos MP, DuBridge RB.

J Virol. 1988 Oct;62(10):3738-46.


Recombinant shuttle vectors for the study of mutation in mammalian cells.

DuBridge RB, Calos MP.

Mutagenesis. 1988 Jan;3(1):1-9. Review. No abstract available.


Analysis of mutation in human cells by using an Epstein-Barr virus shuttle system.

DuBridge RB, Tang P, Hsia HC, Leong PM, Miller JH, Calos MP.

Mol Cell Biol. 1987 Jan;7(1):379-87.


Amplification of a bovine papillomavirus-simian virus 40 chimera.

DuBridge RB, Lusky M, Botchan MR, Calos MP.

J Virol. 1985 Nov;56(2):625-7.


Transfected DNA is mutated in monkey, mouse, and human cells.

Lebkowski JS, DuBridge RB, Antell EA, Greisen KS, Calos MP.

Mol Cell Biol. 1984 Oct;4(10):1951-60.

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