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Items: 1 to 50 of 253


PPARδ Mediates the Effect of Dietary Fat in Promoting Colorectal Cancer Metastasis.

Wang D, Fu L, Wei J, Xiong Y, DuBois RN.

Cancer Res. 2019 Sep 1;79(17):4480-4490. doi: 10.1158/0008-5472.CAN-19-0384. Epub 2019 Jun 25.


Magnetic Resonance Imaging and Bioluminescence Imaging for Evaluating Tumor Burden in Orthotopic Colon Cancer.

Ravoori MK, Margalit O, Singh S, Kim SH, Wei W, Menter DG, DuBois RN, Kundra V.

Sci Rep. 2019 Apr 15;9(1):6100. doi: 10.1038/s41598-019-42230-w.


Cancer Prevention: A Message from the New Editors-in-Chief.

DuBois RN, Pollak MN.

Cancer Prev Res (Phila). 2019 Jan;12(1):1-2. doi: 10.1158/1940-6207.CAPR-18-0349. Epub 2018 Dec 27. No abstract available.


AACR White Paper: Shaping the Future of Cancer Prevention - A Roadmap for Advancing Science and Public Health.

Lippman SM, Abate-Shen C, Colbert Maresso KL, Colditz GA, Dannenberg AJ, Davidson NE, Disis ML, DuBois RN, Szabo E, Giuliano AR, Hait WN, Lee JJ, Kensler TW, Kramer BS, Limburg P, Maitra A, Martinez ME, Rebbeck TR, Schmitz KH, Vilar E, Hawk ET.

Cancer Prev Res (Phila). 2018 Dec;11(12):735-778. doi: 10.1158/1940-6207.CAPR-18-0421.


Role of prostanoids in gastrointestinal cancer.

Wang D, DuBois RN.

J Clin Invest. 2018 Jul 2;128(7):2732-2742. doi: 10.1172/JCI97953. Epub 2018 May 7. Review.


CXCL1 Is Critical for Premetastatic Niche Formation and Metastasis in Colorectal Cancer.

Wang D, Sun H, Wei J, Cen B, DuBois RN.

Cancer Res. 2017 Jul 1;77(13):3655-3665. doi: 10.1158/0008-5472.CAN-16-3199. Epub 2017 Apr 28.


Krüppel-Like Factor 12 Promotes Colorectal Cancer Growth through Early Growth Response Protein 1.

Kim SH, Park YY, Cho SN, Margalit O, Wang D, DuBois RN.

PLoS One. 2016 Jul 21;11(7):e0159899. doi: 10.1371/journal.pone.0159899. eCollection 2016.


The Role of Prostaglandin E(2) in Tumor-Associated Immunosuppression.

Wang D, DuBois RN.

Trends Mol Med. 2016 Jan;22(1):1-3. doi: 10.1016/j.molmed.2015.11.003. Epub 2015 Dec 17.


AACR Cancer Progress Report 2015.

Baselga J, Bhardwaj N, Cantley LC, DeMatteo R, DuBois RN, Foti M, Gapstur SM, Hahn WC, Helman LJ, Jensen RA, Paskett ED, Lawrence TS, Lutzker SG, Szabo E.

Clin Cancer Res. 2015 Oct 1;21(19 Suppl):S1-128. doi: 10.1158/1078-0432.CCR-15-1846. No abstract available.


Immunosuppression associated with chronic inflammation in the tumor microenvironment.

Wang D, DuBois RN.

Carcinogenesis. 2015 Oct;36(10):1085-93. doi: 10.1093/carcin/bgv123. Epub 2015 Sep 8. Review.


PPARδ and PGE2 signaling pathways communicate and connect inflammation to colorectal cancer.

Wang D, DuBois RN.

Inflamm Cell Signal. 2014 Oct 19;1(6). doi: 10.14800/ics.338.


Prostaglandin E2 Promotes Colorectal Cancer Stem Cell Expansion and Metastasis in Mice.

Wang D, Fu L, Sun H, Guo L, DuBois RN.

Gastroenterology. 2015 Dec;149(7):1884-1895.e4. doi: 10.1053/j.gastro.2015.07.064. Epub 2015 Aug 7.


Role of inflammation and inflammatory mediators in colorectal cancer.

Dubois RN.

Trans Am Clin Climatol Assoc. 2014;125:358-72; discussion 372-3.


CG100649, a novel COX-2 inhibitor, inhibits colorectal adenoma and carcinoma growth in mouse models.

Kim SH, Margalit O, Katoh H, Wang D, Wu H, Xia D, Holla VR, Yang P, DuBois RN.

Invest New Drugs. 2014 Dec;32(6):1105-1112. doi: 10.1007/s10637-014-0144-z. Epub 2014 Aug 3.


Myeloid-derived suppressor cells link inflammation to cancer.

Wang D, DuBois RN.

Oncoimmunology. 2014 Apr 29;3:e28581. eCollection 2014.


Peroxisome proliferator-activated receptor δ promotes colonic inflammation and tumor growth.

Wang D, Fu L, Ning W, Guo L, Sun X, Dey SK, Chaturvedi R, Wilson KT, DuBois RN.

Proc Natl Acad Sci U S A. 2014 May 13;111(19):7084-9. doi: 10.1073/pnas.1324233111. Epub 2014 Apr 24.


An inflammatory mediator, prostaglandin E2, in colorectal cancer.

Wang D, DuBois RN.

Cancer J. 2013 Nov-Dec;19(6):502-10. doi: 10.1097/PPO.0000000000000003. Review.


CXCR2-expressing myeloid-derived suppressor cells are essential to promote colitis-associated tumorigenesis.

Katoh H, Wang D, Daikoku T, Sun H, Dey SK, Dubois RN.

Cancer Cell. 2013 Nov 11;24(5):631-44. doi: 10.1016/j.ccr.2013.10.009.


HIG2 promotes colorectal cancer progression via hypoxia-dependent and independent pathways.

Kim SH, Wang D, Park YY, Katoh H, Margalit O, Sheffer M, Wu H, Holla VR, Lee JS, DuBois RN.

Cancer Lett. 2013 Dec 1;341(2):159-65. doi: 10.1016/j.canlet.2013.07.028. Epub 2013 Aug 2.


Changes in cancer cell metabolism revealed by direct sample analysis with MALDI mass spectrometry.

Pirman DA, Efuet E, Ding XP, Pan Y, Tan L, Fischer SM, DuBois RN, Yang P.

PLoS One. 2013 Apr 26;8(4):e61379. doi: 10.1371/journal.pone.0061379. Print 2013.


Urinary PGE-M: a promising cancer biomarker.

Wang D, DuBois RN.

Cancer Prev Res (Phila). 2013 Jun;6(6):507-10. doi: 10.1158/1940-6207.CAPR-13-0153. Epub 2013 May 1.


Prostaglandin E2 regulates pancreatic stellate cell activity via the EP4 receptor.

Charo C, Holla V, Arumugam T, Hwang R, Yang P, Dubois RN, Menter DG, Logsdon CD, Ramachandran V.

Pancreas. 2013 Apr;42(3):467-74. doi: 10.1097/MPA.0b013e318264d0f8.


PPARγ agonists target aromatase via both PGE2 and BRCA1.

Margalit O, Wang D, Dubois RN.

Cancer Prev Res (Phila). 2012 Oct;5(10):1169-72. doi: 10.1158/1940-6207.CAPR-12-0365.


The role of anti-inflammatory drugs in colorectal cancer.

Wang D, DuBois RN.

Annu Rev Med. 2013;64:131-44. doi: 10.1146/annurev-med-112211-154330. Epub 2012 Sep 27. Review.


AACR Cancer Progress Report 2012.

Cantley LC, Dalton WS, DuBois RN, Finn OJ, Futreal PA, Golub TR, Hait WN, Lozano G, Maris JM, Nelson WG, Sawyers CL, Schreiber SL, Spitz MR, Steeg PS.

Clin Cancer Res. 2012 Nov 1;18(21 Suppl):S1-100. doi: 10.1158/1078-0432.CCR-12-2891. Epub 2012 Sep 11. No abstract available.


Biomarkers, bundled payments, and colorectal cancer care.

Ross W, Lynch P, Raju G, Rodriguez A, Burke T, Hafemeister L, Hawk E, Wu X, Dubois RN, Mishra L.

Genes Cancer. 2012 Jan;3(1):16-22. doi: 10.1177/1947601912448958.


Metronomic topotecan for colorectal cancer: a promising new option.

Wang D, Margalit O, DuBois RN.

Gut. 2013 Feb;62(2):190-1. doi: 10.1136/gutjnl-2012-302410. Epub 2012 Jun 8. No abstract available.


Genetic polymorphisms in MicroRNA-related genes as predictors of clinical outcomes in colorectal adenocarcinoma patients.

Lin M, Gu J, Eng C, Ellis LM, Hildebrandt MA, Lin J, Huang M, Calin GA, Wang D, Dubois RN, Hawk ET, Wu X.

Clin Cancer Res. 2012 Jul 15;18(14):3982-91. doi: 10.1158/1078-0432.CCR-11-2951. Epub 2012 Jun 1.


The role of the PGE2-aromatase pathway in obesity-associated breast inflammation.

Wang D, DuBois RN.

Cancer Discov. 2012 Apr;2(4):308-10. doi: 10.1158/2159-8290.CD-12-0078.


Prostaglandins in cancer cell adhesion, migration, and invasion.

Menter DG, Dubois RN.

Int J Cell Biol. 2012;2012:723419. doi: 10.1155/2012/723419. Epub 2012 Feb 29.


Associations between obesity and cancer: the role of fatty acid synthase.

Wang D, Dubois RN.

J Natl Cancer Inst. 2012 Mar 7;104(5):343-5. doi: 10.1093/jnci/djs010. Epub 2012 Feb 6. No abstract available.


Overview of the AACR Clinical and Translational Cancer Research Think Tank meeting.

Anderson KC, DuBois RN.

Clin Cancer Res. 2012 Feb 1;18(3):607-11. doi: 10.1158/1078-0432.CCR-11-3228. No abstract available.


Prostaglandin E2 promotes intestinal tumor growth via DNA methylation.

Xia D, Wang D, Kim SH, Katoh H, DuBois RN.

Nat Med. 2012 Jan 22;18(2):224-6. doi: 10.1038/nm.2608.


Epoxyeicosatrienoic acids: a double-edged sword in cardiovascular diseases and cancer.

Wang D, Dubois RN.

J Clin Invest. 2012 Jan;122(1):19-22. doi: 10.1172/JCI61453. Epub 2011 Dec 19.


APOBEC3G promotes liver metastasis in an orthotopic mouse model of colorectal cancer and predicts human hepatic metastasis.

Ding Q, Chang CJ, Xie X, Xia W, Yang JY, Wang SC, Wang Y, Xia J, Chen L, Cai C, Li H, Yen CJ, Kuo HP, Lee DF, Lang J, Huo L, Cheng X, Chen YJ, Li CW, Jeng LB, Hsu JL, Li LY, Tan A, Curley SA, Ellis LM, Dubois RN, Hung MC.

J Clin Invest. 2011 Nov;121(11):4526-36. doi: 10.1172/JCI45008. Epub 2011 Oct 10.


ANGPTL4 induction by prostaglandin E2 under hypoxic conditions promotes colorectal cancer progression.

Kim SH, Park YY, Kim SW, Lee JS, Wang D, DuBois RN.

Cancer Res. 2011 Nov 15;71(22):7010-20. doi: 10.1158/0008-5472.CAN-11-1262. Epub 2011 Sep 21.


Peroxisome proliferator-activated receptor δ confers resistance to peroxisome proliferator-activated receptor γ-induced apoptosis in colorectal cancer cells.

Wang D, Ning W, Xie D, Guo L, DuBois RN.

Oncogene. 2012 Feb 23;31(8):1013-23. doi: 10.1038/onc.2011.299. Epub 2011 Jul 18.


Nuclear orphan receptor NR4A2 modulates fatty acid oxidation pathways in colorectal cancer.

Holla VR, Wu H, Shi Q, Menter DG, DuBois RN.

J Biol Chem. 2011 Aug 26;286(34):30003-9. doi: 10.1074/jbc.M110.184697. Epub 2011 Jul 10.


The tumor microenvironment in colorectal carcinogenesis.

Peddareddigari VG, Wang D, Dubois RN.

Cancer Microenviron. 2010 Mar 5;3(1):149-66. doi: 10.1007/s12307-010-0038-3.


The Crosstalk of PTGS2 and EGF Signaling Pathways in Colorectal Cancer.

Wang D, Xia D, Dubois RN.

Cancers (Basel). 2011 Oct 14;3(4):3894-908. doi: 10.3390/cancers3043894.


Therapeutic potential of peroxisome proliferator-activated receptors in chronic inflammation and colorectal cancer.

Wang D, DuBois RN.

Gastroenterol Clin North Am. 2010 Sep;39(3):697-707. doi: 10.1016/j.gtc.2010.08.014. Review.


Tailoring treatment in translational cancer research: An Interview with Raymond N. DuBois, MD, PhD. Interviewed by Elaine Musgrave.

DuBois RN.

Clin Transl Sci. 2009 Jun;2(3):178-9. doi: 10.1111/j.1752-8062.2008.00115.x. No abstract available.


Human enhancer of filamentation 1 Is a mediator of hypoxia-inducible factor-1alpha-mediated migration in colorectal carcinoma cells.

Kim SH, Xia D, Kim SW, Holla V, Menter DG, Dubois RN.

Cancer Res. 2010 May 15;70(10):4054-63. doi: 10.1158/0008-5472.CAN-09-2110. Epub 2010 May 4.


Prostaglandin Gbetagamma signaling stimulates gastrulation movements by limiting cell adhesion through Snai1a stabilization.

Speirs CK, Jernigan KK, Kim SH, Cha YI, Lin F, Sepich DS, DuBois RN, Lee E, Solnica-Krezel L.

Development. 2010 Apr;137(8):1327-37. doi: 10.1242/dev.045971.


Cyclooxygenase-2 and cancer treatment: understanding the risk should be worth the reward.

Menter DG, Schilsky RL, DuBois RN.

Clin Cancer Res. 2010 Mar 1;16(5):1384-90. doi: 10.1158/1078-0432.CCR-09-0788. Epub 2010 Feb 23. Review.


Eicosanoids and cancer.

Wang D, Dubois RN.

Nat Rev Cancer. 2010 Mar;10(3):181-93. doi: 10.1038/nrc2809. Epub 2010 Feb 19. Review.


HEF1 is a crucial mediator of the proliferative effects of prostaglandin E(2) on colon cancer cells.

Xia D, Holla VR, Wang D, Menter DG, DuBois RN.

Cancer Res. 2010 Jan 15;70(2):824-31. doi: 10.1158/0008-5472.CAN-09-2105. Epub 2010 Jan 12.


The role of COX-2 in intestinal inflammation and colorectal cancer.

Wang D, Dubois RN.

Oncogene. 2010 Feb 11;29(6):781-8. doi: 10.1038/onc.2009.421. Epub 2009 Nov 30. Review.


The role of chemokines in intestinal inflammation and cancer.

Wang D, Dubois RN, Richmond A.

Curr Opin Pharmacol. 2009 Dec;9(6):688-96. doi: 10.1016/j.coph.2009.08.003. Epub 2009 Sep 4. Review.

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