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Items: 12


The biology of RAGE and its ligands: uncovering mechanisms at the heart of diabetes and its complications.

Yan SF, Barile GR, D'Agati V, Du Yan S, Ramasamy R, Schmidt AM.

Curr Diab Rep. 2007 Apr;7(2):146-53. Review.


RAGE and its ligands: a lasting memory in diabetic complications?

Yan SF, Ramasamy R, Bucciarelli LG, Wendt T, Lee LK, Hudson BI, Stern DM, Lalla E, DU Yan S, Rong LL, Naka Y, Schmidt AM.

Diab Vasc Dis Res. 2004 May;1(1):10-20. Review.


RAGE potentiates Abeta-induced perturbation of neuronal function in transgenic mice.

Arancio O, Zhang HP, Chen X, Lin C, Trinchese F, Puzzo D, Liu S, Hegde A, Yan SF, Stern A, Luddy JS, Lue LF, Walker DG, Roher A, Buttini M, Mucke L, Li W, Schmidt AM, Kindy M, Hyslop PA, Stern DM, Du Yan SS.

EMBO J. 2004 Oct 13;23(20):4096-105. Epub 2004 Sep 30.


LRP/amyloid beta-peptide interaction mediates differential brain efflux of Abeta isoforms.

Deane R, Wu Z, Sagare A, Davis J, Du Yan S, Hamm K, Xu F, Parisi M, LaRue B, Hu HW, Spijkers P, Guo H, Song X, Lenting PJ, Van Nostrand WE, Zlokovic BV.

Neuron. 2004 Aug 5;43(3):333-44.


RAGE mediates amyloid-beta peptide transport across the blood-brain barrier and accumulation in brain.

Deane R, Du Yan S, Submamaryan RK, LaRue B, Jovanovic S, Hogg E, Welch D, Manness L, Lin C, Yu J, Zhu H, Ghiso J, Frangione B, Stern A, Schmidt AM, Armstrong DL, Arnold B, Liliensiek B, Nawroth P, Hofman F, Kindy M, Stern D, Zlokovic B.

Nat Med. 2003 Jul;9(7):907-13.


Key signaling pathways regulate the biological activities and accumulation of amyloid-beta.

Wyss-Coray T, McConlogue L, Kindy M, Schmidt AM, Du Yan S, Stern DM.

Neurobiol Aging. 2001 Nov-Dec;22(6):967-73. Review. No abstract available.


Familial amyloid polyneuropathy: receptor for advanced glycation end products-dependent triggering of neuronal inflammatory and apoptotic pathways.

Sousa MM, Du Yan S, Fernandes R, Guimaraes A, Stern D, Saraiva MJ.

J Neurosci. 2001 Oct 1;21(19):7576-86.


beta-amyloid-induced migration of monocytes across human brain endothelial cells involves RAGE and PECAM-1.

Giri R, Shen Y, Stins M, Du Yan S, Schmidt AM, Stern D, Kim KS, Zlokovic B, Kalra VK.

Am J Physiol Cell Physiol. 2000 Dec;279(6):C1772-81.


Amyloid beta -peptide-binding alcohol dehydrogenase is a component of the cellular response to nutritional stress.

Du Yan S, Zhu Y, Stern ED, Hwang YC, Hori O, Ogawa S, Frosch MP, Connolly ES Jr, McTaggert R, Pinsky DJ, Clarke S, Stern DM, Ramasamy R.

J Biol Chem. 2000 Sep 1;275(35):27100-9.


N(epsilon)-(carboxymethyl)lysine adducts of proteins are ligands for receptor for advanced glycation end products that activate cell signaling pathways and modulate gene expression.

Kislinger T, Fu C, Huber B, Qu W, Taguchi A, Du Yan S, Hofmann M, Yan SF, Pischetsrieder M, Stern D, Schmidt AM.

J Biol Chem. 1999 Oct 29;274(44):31740-9.


Amyloid-beta peptide-receptor for advanced glycation endproduct interaction elicits neuronal expression of macrophage-colony stimulating factor: a proinflammatory pathway in Alzheimer disease.

Du Yan S, Zhu H, Fu J, Yan SF, Roher A, Tourtellotte WW, Rajavashisth T, Chen X, Godman GC, Stern D, Schmidt AM.

Proc Natl Acad Sci U S A. 1997 May 13;94(10):5296-301.


Nuclear factor interleukin 6 motifs mediate tissue-specific gene transcription in hypoxia.

Yan SF, Zou YS, Mendelsohn M, Gao Y, Naka Y, Du Yan S, Pinsky D, Stern D.

J Biol Chem. 1997 Feb 14;272(7):4287-94.

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