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Items: 19

1.

Pharmacokinetics and pharmacodynamics of tecarfarin, a novel vitamin K antagonist oral anticoagulant.

Albrecht D, Ellis D, Canafax DM, Combs D, Druzgala P, Milner PG, Midei MG.

Thromb Haemost. 2017 Apr 3;117(4):706-717. doi: 10.1160/TH16-08-0623. Epub 2017 Feb 9.

PMID:
28180234
2.

Metabolism and pharmacokinetics of naronapride (ATI-7505), a serotonin 5-HT(4) receptor agonist for gastrointestinal motility disorders.

Bowersox SS, Lightning LK, Rao S, Palme M, Ellis D, Coleman R, Davies AM, Kumaraswamy P, Druzgala P.

Drug Metab Dispos. 2011 Jul;39(7):1170-80. doi: 10.1124/dmd.110.037564. Epub 2011 Mar 29.

PMID:
21447732
3.

Antithrombotic activity of the novel oral anticoagulant, Tecarfarin [Sodium 3-[4-((1,1,1,3,3,3-hexafluoro-2-methylpropan-2-yloxy) carbonyl) benzyl]-2-oxo-2H-chromen-4-olate] in animal models.

Bowersox SS, Canafax D, Druzgala P, Milner P, Weitz JI.

Thromb Res. 2010 Nov;126(5):e383-8. doi: 10.1016/j.thromres.2010.08.025.

PMID:
20869102
4.

Effect of tecarfarin, a novel vitamin K epoxide reductase inhibitor, on coagulation in beagle dogs.

Choppin A, Irwin I, Lach L, McDonald MG, Rettie AE, Shao L, Becker C, Palme MP, Paliard X, Bowersox S, Dennis DM, Druzgala P.

Br J Pharmacol. 2009 Nov;158(6):1536-47. doi: 10.1111/j.1476-5381.2009.00420.x. Epub 2009 Oct 20.

5.

Pharmacodynamic effects of a novel prokinetic 5-HT receptor agonist, ATI-7505, in humans.

Camilleri M, Vazquez-Roque MI, Burton D, Ford T, McKinzie S, Zinsmeister AR, Druzgala P.

Neurogastroenterol Motil. 2007 Jan;19(1):30-8.

PMID:
17187586
6.

Structure-activity relationships and electrophysiological effects of short-acting amiodarone homologs in guinea pig isolated heart.

Morey TE, Seubert CN, Raatikainen MJ, Martynyuk AE, Druzgala P, Milner P, Gonzalez MD, Dennis DM.

J Pharmacol Exp Ther. 2001 Apr;297(1):260-6.

PMID:
11259553
7.

Potent and reversible effects of ATI-2001 on atrial and atrioventricular nodal electrophysiological properties in guinea pig isolated perfused heart.

Raatikainen MJ, Morey TE, Druzgala P, Milner P, Gonzalez MD, Dennis DM.

J Pharmacol Exp Ther. 2000 Nov;295(2):779-85.

PMID:
11046118
8.

Chemistry of loteprednol etabonate and related steroids. II. Reactions at ring C and NMR structural studies of the resulting compounds.

Rachwal S, Druzgala P, Liu ZZ, Vlasak J, Brewster ME, Pop E.

Steroids. 1998 Apr;63(4):193-201.

PMID:
9589553
9.

Physicochemical properties and in vitro toxicity of cationic liposome cDNA complexes.

Schreier H, Gagné L, Bock T, Erdos GW, Druzgala P, Conary JT, Müller BW.

Pharm Acta Helv. 1997 Sep;72(4):215-23.

PMID:
9372644
10.

Electrophysiological effects of a novel, short-acting and potent ester derivative of amiodarone, ATI-2001, in guinea pig isolated heart.

Raatikainen MJ, Napolitano CA, Druzgala P, Dennis DM.

J Pharmacol Exp Ther. 1996 Jun;277(3):1454-63.

PMID:
8667210
11.

Efficacy of a 3-substituted versus 17-substituted chemical delivery system for estradiol brain targeting.

Brewster ME, Druzgala PJ, Anderson WR, Huang MJ, Bodor N, Pop E.

J Pharm Sci. 1995 Jan;84(1):38-43.

PMID:
7714741
12.

Effect of molecular manipulation on the estrogenic activity of a brain-targeting estradiol chemical delivery system.

Brewster ME, Bartruff MS, Anderson WR, Druzgala PJ, Bodor N, Pop E.

J Med Chem. 1994 Nov 25;37(24):4237-44.

PMID:
7990122
13.

The effect of dihydronicotinate N-substitution on the brain-targeting efficacy of a zidovudine chemical delivery system.

Brewster ME, Pop E, Braunstein AJ, Pop AC, Druzgala P, Dinculescu A, Anderson W, Elkoussi A, Bodor N.

Pharm Res. 1993 Sep;10(9):1356-62.

PMID:
8234177
14.

Pharmacokinetic characterization and tissue distribution of the new glucocorticoid soft drug loteprednol etabonate in rats and dogs.

Hochhaus G, Chen LS, Ratka A, Druzgala P, Howes J, Bodor N, Derendorf H.

J Pharm Sci. 1992 Dec;81(12):1210-5.

PMID:
1491342
15.

New water-soluble pilocarpine derivatives with enhanced and sustained muscarinic activity.

Druzgala P, Winwood D, Drewniak-Deyrup M, Smith S, Bodor N, Kaminski JJ.

Pharm Res. 1992 Mar;9(3):372-7.

PMID:
1614970
16.
17.

Ocular absorption and distribution of loteprednol etabonate, a soft steroid, in rabbit eyes.

Druzgala P, Wu WM, Bodor N.

Curr Eye Res. 1991 Oct;10(10):933-7.

PMID:
1959381
19.

Soft drugs--10. Blanching activity and receptor binding affinity of a new type of glucocorticoid: loteprednol etabonate.

Druzgala P, Hochhaus G, Bodor N.

J Steroid Biochem Mol Biol. 1991 Feb;38(2):149-54.

PMID:
2004037

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