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Characterization of Terminal Iron(III)-Oxo and Iron(III)-Hydroxo Complexes Derived from O2 Activation.

Gordon Z, Miller TJ, Leahy CA, Matson EM, Burgess M, Drummond MJ, Popescu CV, Smith CM, Lord RL, Rodríguez-López J, Fout AR.

Inorg Chem. 2019 Dec 2;58(23):15801-15811. doi: 10.1021/acs.inorgchem.9b02079. Epub 2019 Nov 12.


Mitochondrial PE potentiates respiratory enzymes to amplify skeletal muscle aerobic capacity.

Heden TD, Johnson JM, Ferrara PJ, Eshima H, Verkerke ARP, Wentzler EJ, Siripoksup P, Narowski TM, Coleman CB, Lin CT, Ryan TE, Reidy PT, de Castro Brás LE, Karner CM, Burant CF, Maschek JA, Cox JE, Mashek DG, Kardon G, Boudina S, Zeczycki TN, Rutter J, Shaikh SR, Vance JE, Drummond MJ, Neufer PD, Funai K.

Sci Adv. 2019 Sep 11;5(9):eaax8352. doi: 10.1126/sciadv.aax8352. eCollection 2019 Sep.


Macrophage Regulation of Muscle Regrowth From Disuse in Aging.

Reidy PT, Dupont-Versteegden EE, Drummond MJ.

Exerc Sport Sci Rev. 2019 Oct;47(4):246-250. doi: 10.1249/JES.0000000000000201.


Food literacy programmes in secondary schools: a systematic literature review and narrative synthesis of quantitative and qualitative evidence.

Bailey CJ, Drummond MJ, Ward PR.

Public Health Nutr. 2019 Oct;22(15):2891-2913. doi: 10.1017/S1368980019001666. Epub 2019 Jul 10.


Radical Rebound Hydroxylation Versus H-Atom Transfer in Non-Heme Iron(III)-Hydroxo Complexes: Reactivity and Structural Differentiation.

Drummond MJ, Ford CL, Gray DL, Popescu CV, Fout AR.

J Am Chem Soc. 2019 Apr 24;141(16):6639-6650. doi: 10.1021/jacs.9b01516. Epub 2019 Apr 10.


Aging impairs mouse skeletal muscle macrophage polarization and muscle-specific abundance during recovery from disuse.

Reidy PT, McKenzie AI, Mahmassani ZS, Petrocelli JJ, Nelson DB, Lindsay CC, Gardner JE, Morrow VR, Keefe AC, Huffaker TB, Stoddard GJ, Kardon G, O'Connell RM, Drummond MJ.

Am J Physiol Endocrinol Metab. 2019 Jul 1;317(1):E85-E98. doi: 10.1152/ajpendo.00422.2018. Epub 2019 Apr 9.


Anti-inflammatory microRNA-146a protects mice from diet-induced metabolic disease.

Runtsch MC, Nelson MC, Lee SH, Voth W, Alexander M, Hu R, Wallace J, Petersen C, Panic V, Villanueva CJ, Evason KJ, Bauer KM, Mosbruger T, Boudina S, Bronner M, Round JL, Drummond MJ, O'Connell RM.

PLoS Genet. 2019 Feb 15;15(2):e1007970. doi: 10.1371/journal.pgen.1007970. eCollection 2019 Feb.


Disuse-induced insulin resistance susceptibility coincides with a dysregulated skeletal muscle metabolic transcriptome.

Mahmassani ZS, Reidy PT, McKenzie AI, Stubben C, Howard MT, Drummond MJ.

J Appl Physiol (1985). 2019 May 1;126(5):1419-1429. doi: 10.1152/japplphysiol.01093.2018. Epub 2019 Feb 14.


An accumulation of muscle macrophages is accompanied by altered insulin sensitivity after reduced activity and recovery.

Reidy PT, Yonemura NM, Madsen JH, McKenzie AI, Mahmassani ZS, Rondina MT, Lin YK, Kaput K, Drummond MJ.

Acta Physiol (Oxf). 2019 Jun;226(2):e13251. doi: 10.1111/apha.13251. Epub 2019 Jan 30.


Age-dependent skeletal muscle transcriptome response to bed rest-induced atrophy.

Mahmassani ZS, Reidy PT, McKenzie AI, Stubben C, Howard MT, Drummond MJ.

J Appl Physiol (1985). 2019 Apr 1;126(4):894-902. doi: 10.1152/japplphysiol.00811.2018. Epub 2019 Jan 3.


Skeletal muscle ceramides and relationship with insulin sensitivity after 2 weeks of simulated sedentary behaviour and recovery in healthy older adults.

Reidy PT, McKenzie AI, Mahmassani Z, Morrow VR, Yonemura NM, Hopkins PN, Marcus RL, Rondina MT, Lin YK, Drummond MJ.

J Physiol. 2018 Nov;596(21):5217-5236. doi: 10.1113/JP276798. Epub 2018 Oct 9.


High-Intensity Multimodal Resistance Training Improves Muscle Function, Symmetry during a Sit-to-Stand Task, and Physical Function Following Hip Fracture.

Briggs RA, Houck JR, LaStayo PC, Fritz JM, Drummond MJ, Marcus RL.

J Nutr Health Aging. 2018;22(3):431-438. doi: 10.1007/s12603-017-0977-1.


Muscle Quality Improves with Extended High-Intensity Resistance Training after Hip Fracture.

Briggs RA, Houck JR, Drummond MJ, Fritz JM, LaStayo PC, Marcus RL.

J Frailty Aging. 2018;7(1):51-56. doi: 10.14283/jfa.2017.31.


Effect of light-load resistance exercise on postprandial amino acid transporter expression in elderly men.

Agergaard J, Bülow J, Jensen JK, Reitelseder S, Bornø A, Drummond MJ, Schjerling P, Holm L.

Physiol Rep. 2017 Sep;5(18). pii: e13444. doi: 10.14814/phy2.13444. Epub 2017 Sep 27.


Aging-related effects of bed rest followed by eccentric exercise rehabilitation on skeletal muscle macrophages and insulin sensitivity.

Reidy PT, Lindsay CC, McKenzie AI, Fry CS, Supiano MA, Marcus RL, LaStayo PC, Drummond MJ.

Exp Gerontol. 2018 Jul 1;107:37-49. doi: 10.1016/j.exger.2017.07.001. Epub 2017 Jul 10.


Leucine Differentially Regulates Gene-Specific Translation in Mouse Skeletal Muscle.

Drummond MJ, Reidy PT, Baird LM, Dalley BK, Howard MT.

J Nutr. 2017 Sep;147(9):1616-1623. doi: 10.3945/jn.117.251181. Epub 2017 Jun 14.


Postexercise essential amino acid supplementation amplifies skeletal muscle satellite cell proliferation in older men 24 hours postexercise.

Reidy PT, Fry CS, Dickinson JM, Drummond MJ, Rasmussen BB.

Physiol Rep. 2017 Jun;5(11). pii: e13269. doi: 10.14814/phy2.13269.


Neuromuscular Electrical Stimulation Combined with Protein Ingestion Preserves Thigh Muscle Mass But Not Muscle Function in Healthy Older Adults During 5 Days of Bed Rest.

Reidy PT, McKenzie AI, Brunker P, Nelson DS, Barrows KM, Supiano M, LaStayo PC, Drummond MJ.

Rejuvenation Res. 2017 Dec;20(6):449-461. doi: 10.1089/rej.2017.1942. Epub 2017 Jun 19.


Tuning the Fe(II/III) Redox Potential in Nonheme Fe(II)-Hydroxo Complexes through Primary and Secondary Coordination Sphere Modifications.

Gordon Z, Drummond MJ, Matson EM, Bogart JA, Schelter EJ, Lord RL, Fout AR.

Inorg Chem. 2017 May 1;56(9):4852-4863. doi: 10.1021/acs.inorgchem.6b03071. Epub 2017 Apr 10.


Asymmetries Identified in Sit-to-Stand Task Explain Physical Function After Hip Fracture.

Briggs RA, Houck JR, Drummond MJ, Fritz JM, LaStayo PC, Marcus RL.

J Geriatr Phys Ther. 2018 Oct/Dec;41(4):210-217. doi: 10.1519/JPT.0000000000000122.


Intramyocellular ceramides and skeletal muscle mitochondrial respiration are partially regulated by Toll-like receptor 4 during hindlimb unloading.

Kwon OS, Nelson DS, Barrows KM, O'Connell RM, Drummond MJ.

Am J Physiol Regul Integr Comp Physiol. 2016 Nov 1;311(5):R879-R887. doi: 10.1152/ajpregu.00253.2016. Epub 2016 Aug 31.


A pilot study examining the impact of exercise training on skeletal muscle genes related to the TLR signaling pathway in older adults following hip fracture recovery.

McKenzie AI, Briggs RA, Barrows KM, Nelson DS, Kwon OS, Hopkins PN, Higgins TF, Marcus RL, Drummond MJ.

J Appl Physiol (1985). 2017 Jan 1;122(1):68-75. doi: 10.1152/japplphysiol.00714.2016. Epub 2016 Oct 27.


Light-load resistance exercise increases muscle protein synthesis and hypertrophy signaling in elderly men.

Agergaard J, Bülow J, Jensen JK, Reitelseder S, Drummond MJ, Schjerling P, Scheike T, Serena A, Holm L.

Am J Physiol Endocrinol Metab. 2017 Apr 1;312(4):E326-E338. doi: 10.1152/ajpendo.00164.2016. Epub 2016 Oct 25.


Influence of ageing and essential amino acids on quantitative patterns of troponin T alternative splicing in human skeletal muscle.

Coble J, Schilder RJ, Berg A, Drummond MJ, Rasmussen BB, Kimball SR.

Appl Physiol Nutr Metab. 2015 Aug;40(8):788-796. doi: 10.1139/apnm-2014-0568. Epub 2015 Mar 23.


Age-related differences in lean mass, protein synthesis and skeletal muscle markers of proteolysis after bed rest and exercise rehabilitation.

Tanner RE, Brunker LB, Agergaard J, Barrows KM, Briggs RA, Kwon OS, Young LM, Hopkins PN, Volpi E, Marcus RL, LaStayo PC, Drummond MJ.

J Physiol. 2015 Sep 15;593(18):4259-73. doi: 10.1113/JP270699. Epub 2015 Jul 31.


MyD88 regulates physical inactivity-induced skeletal muscle inflammation, ceramide biosynthesis signaling, and glucose intolerance.

Kwon OS, Tanner RE, Barrows KM, Runtsch M, Symons JD, Jalili T, Bikman BT, McClain DA, O'Connell RM, Drummond MJ.

Am J Physiol Endocrinol Metab. 2015 Jul 1;309(1):E11-21. doi: 10.1152/ajpendo.00124.2015. Epub 2015 May 12.


Effect of age on basal muscle protein synthesis and mTORC1 signaling in a large cohort of young and older men and women.

Markofski MM, Dickinson JM, Drummond MJ, Fry CS, Fujita S, Gundermann DM, Glynn EL, Jennings K, Paddon-Jones D, Reidy PT, Sheffield-Moore M, Timmerman KL, Rasmussen BB, Volpi E.

Exp Gerontol. 2015 May;65:1-7. doi: 10.1016/j.exger.2015.02.015. Epub 2015 Feb 28.


Leucine-enriched amino acid ingestion after resistance exercise prolongs myofibrillar protein synthesis and amino acid transporter expression in older men.

Dickinson JM, Gundermann DM, Walker DK, Reidy PT, Borack MS, Drummond MJ, Arora M, Volpi E, Rasmussen BB.

J Nutr. 2014 Nov;144(11):1694-702. doi: 10.3945/jn.114.198671. Epub 2014 Sep 3.


A practical dietary strategy to maximize the anabolic response to protein in aging muscle.

Drummond MJ.

J Gerontol A Biol Sci Med Sci. 2015 Jan;70(1):55-6. doi: 10.1093/gerona/glu157. Epub 2014 Sep 4. No abstract available.


The importance of dietary protein for muscle health in inactive, hospitalized older adults.

Thalacker-Mercer AE, Drummond MJ.

Ann N Y Acad Sci. 2014 Nov;1328:1-9. doi: 10.1111/nyas.12509. Epub 2014 Aug 12. Review.


Skeletal muscle Ras-related GTP binding B mRNA and protein expression is increased after essential amino acid ingestion in healthy humans.

Carlin MB, Tanner RE, Agergaard J, Jalili T, McClain DA, Drummond MJ.

J Nutr. 2014 Sep;144(9):1409-14. doi: 10.3945/jn.114.196691. Epub 2014 Jul 23.


Intramuscular fat and inflammation differ in older adults: the impact of frailty and inactivity.

Addison O, Drummond MJ, LaStayo PC, Dibble LE, Wende AR, McClain DA, Marcus RL.

J Nutr Health Aging. 2014 May;18(5):532-8. doi: 10.1007/s12603-014-0019-1.


Insulin increases mRNA abundance of the amino acid transporter SLC7A5/LAT1 via an mTORC1-dependent mechanism in skeletal muscle cells.

Walker DK, Drummond MJ, Dickinson JM, Borack MS, Jennings K, Volpi E, Rasmussen BB.

Physiol Rep. 2014 Mar 20;2(3):e00238. doi: 10.1002/phy2.238. Print 2014.


Soy-dairy protein blend and whey protein ingestion after resistance exercise increases amino acid transport and transporter expression in human skeletal muscle.

Reidy PT, Walker DK, Dickinson JM, Gundermann DM, Drummond MJ, Timmerman KL, Cope MB, Mukherjea R, Jennings K, Volpi E, Rasmussen BB.

J Appl Physiol (1985). 2014 Jun 1;116(11):1353-64. doi: 10.1152/japplphysiol.01093.2013. Epub 2014 Apr 3.


Effect of leucine supplementation on fat free mass with prolonged hypoxic exposure during a 13-day trek to Everest Base Camp: a double-blind randomized study.

Wing-Gaia SL, Gershenoff DC, Drummond MJ, Askew EW.

Appl Physiol Nutr Metab. 2014 Mar;39(3):318-23. doi: 10.1139/apnm-2013-0319. Epub 2013 Sep 25.


Downregulation of E3 ubiquitin ligases and mitophagy-related genes in skeletal muscle of physically inactive, frail older women: a cross-sectional comparison.

Drummond MJ, Addison O, Brunker L, Hopkins PN, McClain DA, LaStayo PC, Marcus RL.

J Gerontol A Biol Sci Med Sci. 2014 Aug;69(8):1040-8. doi: 10.1093/gerona/glu004. Epub 2014 Feb 13.


Short-term bed rest increases TLR4 and IL-6 expression in skeletal muscle of older adults.

Drummond MJ, Timmerman KL, Markofski MM, Walker DK, Dickinson JM, Jamaluddin M, Brasier AR, Rasmussen BB, Volpi E.

Am J Physiol Regul Integr Comp Physiol. 2013 Aug 1;305(3):R216-23. doi: 10.1152/ajpregu.00072.2013. Epub 2013 Jun 12.


Addition of carbohydrate or alanine to an essential amino acid mixture does not enhance human skeletal muscle protein anabolism.

Glynn EL, Fry CS, Timmerman KL, Drummond MJ, Volpi E, Rasmussen BB.

J Nutr. 2013 Mar;143(3):307-14. doi: 10.3945/jn.112.168203. Epub 2013 Jan 23.


Protein blend ingestion following resistance exercise promotes human muscle protein synthesis.

Reidy PT, Walker DK, Dickinson JM, Gundermann DM, Drummond MJ, Timmerman KL, Fry CS, Borack MS, Cope MB, Mukherjea R, Jennings K, Volpi E, Rasmussen BB.

J Nutr. 2013 Apr;143(4):410-6. doi: 10.3945/jn.112.168021. Epub 2013 Jan 23.


Skeletal muscle autophagy and protein breakdown following resistance exercise are similar in younger and older adults.

Fry CS, Drummond MJ, Glynn EL, Dickinson JM, Gundermann DM, Timmerman KL, Walker DK, Volpi E, Rasmussen BB.

J Gerontol A Biol Sci Med Sci. 2013 May;68(5):599-607. doi: 10.1093/gerona/gls209. Epub 2012 Oct 22.


Paraplegia increases skeletal muscle autophagy.

Fry CS, Drummond MJ, Lujan HL, DiCarlo SE, Rasmussen BB.

Muscle Nerve. 2012 Nov;46(5):793-8. doi: 10.1002/mus.23423.


Rapamycin does not affect post-absorptive protein metabolism in human skeletal muscle.

Dickinson JM, Drummond MJ, Fry CS, Gundermann DM, Walker DK, Timmerman KL, Volpi E, Rasmussen BB.

Metabolism. 2013 Jan;62(1):144-51. doi: 10.1016/j.metabol.2012.07.003. Epub 2012 Sep 6.


Aging differentially affects human skeletal muscle amino acid transporter expression when essential amino acids are ingested after exercise.

Dickinson JM, Drummond MJ, Coben JR, Volpi E, Rasmussen BB.

Clin Nutr. 2013 Apr;32(2):273-80. doi: 10.1016/j.clnu.2012.07.009. Epub 2012 Aug 1.


PAX7+ satellite cells in young and older adults following resistance exercise.

Walker DK, Fry CS, Drummond MJ, Dickinson JM, Timmerman KL, Gundermann DM, Jennings K, Volpi E, Rasmussen BB.

Muscle Nerve. 2012 Jul;46(1):51-9. doi: 10.1002/mus.23266. Epub 2012 May 29.


A moderate acute increase in physical activity enhances nutritive flow and the muscle protein anabolic response to mixed nutrient intake in older adults.

Timmerman KL, Dhanani S, Glynn EL, Fry CS, Drummond MJ, Jennings K, Rasmussen BB, Volpi E.

Am J Clin Nutr. 2012 Jun;95(6):1403-12. doi: 10.3945/ajcn.111.020800. Epub 2012 May 9.


Reactive hyperemia is not responsible for stimulating muscle protein synthesis following blood flow restriction exercise.

Gundermann DM, Fry CS, Dickinson JM, Walker DK, Timmerman KL, Drummond MJ, Volpi E, Rasmussen BB.

J Appl Physiol (1985). 2012 May;112(9):1520-8. doi: 10.1152/japplphysiol.01267.2011. Epub 2012 Feb 23.


Bed rest impairs skeletal muscle amino acid transporter expression, mTORC1 signaling, and protein synthesis in response to essential amino acids in older adults.

Drummond MJ, Dickinson JM, Fry CS, Walker DK, Gundermann DM, Reidy PT, Timmerman KL, Markofski MM, Paddon-Jones D, Rasmussen BB, Volpi E.

Am J Physiol Endocrinol Metab. 2012 May 15;302(9):E1113-22. doi: 10.1152/ajpendo.00603.2011. Epub 2012 Feb 14.


Aging impairs contraction-induced human skeletal muscle mTORC1 signaling and protein synthesis.

Fry CS, Drummond MJ, Glynn EL, Dickinson JM, Gundermann DM, Timmerman KL, Walker DK, Dhanani S, Volpi E, Rasmussen BB.

Skelet Muscle. 2011 Mar 2;1(1):11. doi: 10.1186/2044-5040-1-11.


Exercise, amino acids, and aging in the control of human muscle protein synthesis.

Walker DK, Dickinson JM, Timmerman KL, Drummond MJ, Reidy PT, Fry CS, Gundermann DM, Rasmussen BB.

Med Sci Sports Exerc. 2011 Dec;43(12):2249-58. doi: 10.1249/MSS.0b013e318223b037. Review.

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