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Items: 28


Surface protein engineering increases the circulation time of a cell membrane-based nanotherapeutic.

Krishnamurthy S, Muthukumaran P, Jayakumar MKG, Lisse D, Masurkar ND, Xu C, Chan JM, Drum CL.

Nanomedicine. 2019 Jun;18:169-178. doi: 10.1016/j.nano.2019.02.024. Epub 2019 Mar 8.


Reductions in Postprandial Plasma Allantoin Concentrations With Increasing Doses of Polyphenol Rich Curry Intake - A Randomized Crossover Trial.

Haldar S, Pakkiri LS, Lim J, Chia SC, Ponnalagu S, Drum CL, Henry CJ.

Front Physiol. 2019 Jan 9;9:1899. doi: 10.3389/fphys.2018.01899. eCollection 2018.


The Importance of Sex Stratification in Autoimmune Disease Biomarker Research: A Systematic Review.

Purnamawati K, Ong JA, Deshpande S, Tan WK, Masurkar N, Low JK, Drum CL.

Front Immunol. 2018 Jun 4;9:1208. doi: 10.3389/fimmu.2018.01208. eCollection 2018.


Sources of variability in quantifying circulating thymosin beta-4: literature review and recommendations.

Tan WKY, Purnamawati K, Pakkiri LS, Tan SH, Yang X, Chan MY, Drum CL.

Expert Opin Biol Ther. 2018 Jul;18(sup1):141-147. doi: 10.1080/14712598.2018.1448382. Epub 2018 Mar 12. Review.


Using Extraordinary Optical Transmission to Quantify Cardiac Biomarkers in Human Serum.

Patra A, Ding T, Hong M, Richards AM, Wong TI, Zhou X, Drum CL.

J Vis Exp. 2017 Dec 13;(130). doi: 10.3791/55597.


Thermostable exoshells fold and stabilize recombinant proteins.

Deshpande S, Masurkar ND, Girish VM, Desai M, Chakraborty G, Chan JM, Drum CL.

Nat Commun. 2017 Nov 13;8(1):1442. doi: 10.1038/s41467-017-01585-2.


Direct analysis - no sample preparation - of bioavailable cortisol in human plasma by weak affinity chromatography (WAC).

Ohlson S, Kaur J, Raida M, Niss U, Bengala T, Drum CL, Boehm B, Torres AR.

J Chromatogr B Analyt Technol Biomed Life Sci. 2017 Sep 1;1061-1062:438-444. doi: 10.1016/j.jchromb.2017.07.035. Epub 2017 Jul 21.


Thymosin Beta-4 Is Elevated in Women With Heart Failure With Preserved Ejection Fraction.

Drum CL, Tan WKY, Chan SP, Pakkiri LS, Chong JPC, Liew OW, Ng TP, Ling LH, Sim D, Leong KG, Yeo DPS, Ong HY, Jaufeerally F, Wong RCC, Chai P, Low AF, Davidsson P, Liljeblad M, Söderling AS, Gan LM, Bhat RV, Purnamawati K, Lam CSP, Richards AM.

J Am Heart Assoc. 2017 Jun 13;6(6). pii: e005586. doi: 10.1161/JAHA.117.005586.


Treatment with the MAO-A inhibitor clorgyline elevates monoamine neurotransmitter levels and improves affective phenotypes in a mouse model of Huntington disease.

Garcia-Miralles M, Ooi J, Ferrari Bardile C, Tan LJ, George M, Drum CL, Lin RY, Hayden MR, Pouladi MA.

Exp Neurol. 2016 Apr;278:4-10. doi: 10.1016/j.expneurol.2016.01.019. Epub 2016 Jan 26.


Ergothioneine, an adaptive antioxidant for the protection of injured tissues? A hypothesis.

Halliwell B, Cheah IK, Drum CL.

Biochem Biophys Res Commun. 2016 Feb 5;470(2):245-250. doi: 10.1016/j.bbrc.2015.12.124. Epub 2016 Jan 6. Review.


Component-Specific Analysis of Plasma Protein Corona Formation on Gold Nanoparticles Using Multiplexed Surface Plasmon Resonance.

Patra A, Ding T, Engudar G, Wang Y, Dykas MM, Liedberg B, Kah JC, Venkatesan T, Drum CL.

Small. 2016 Mar 2;12(9):1174-82. doi: 10.1002/smll.201501603. Epub 2015 Sep 10.


Quantification of a cardiac biomarker in human serum using extraordinary optical transmission (EOT).

Ding T, Hong M, Richards AM, Wong TI, Zhou X, Drum CL.

PLoS One. 2015 Mar 16;10(3):e0120974. doi: 10.1371/journal.pone.0120974. eCollection 2015.


Microengineering in cardiovascular research: new developments and translational applications.

Chan JM, Wong KH, Richards AM, Drum CL.

Cardiovasc Res. 2015 Apr 1;106(1):9-18. doi: 10.1093/cvr/cvv049. Epub 2015 Feb 17. Review.


Real-time measurement of thrombin generation using continuous droplet microfluidics.

Yu J, Tao D, Ng EX, Drum CL, Liu AQ, Chen CH.

Biomicrofluidics. 2014 Sep 3;8(5):052108. doi: 10.1063/1.4894747. eCollection 2014 Sep.


Adaptive licensing: taking the next step in the evolution of drug approval.

Eichler HG, Oye K, Baird LG, Abadie E, Brown J, Drum CL, Ferguson J, Garner S, Honig P, Hukkelhoven M, Lim JC, Lim R, Lumpkin MM, Neil G, O'Rourke B, Pezalla E, Shoda D, Seyfert-Margolis V, Sigal EV, Sobotka J, Tan D, Unger TF, Hirsch G.

Clin Pharmacol Ther. 2012 Mar;91(3):426-37. doi: 10.1038/clpt.2011.345. Epub 2012 Feb 15. Review.


Superstructure based on β-CD self-assembly induced by a small guest molecule.

De Sousa FB, Lima AC, Denadai AM, Anconi CP, De Almeida WB, Novato WT, Dos Santos HF, Drum CL, Langer R, Sinisterra RD.

Phys Chem Chem Phys. 2012 Feb 14;14(6):1934-44. doi: 10.1039/c2cp22768a. Epub 2012 Jan 10.


In vivo prevention of arterial restenosis with paclitaxel-encapsulated targeted lipid-polymeric nanoparticles.

Chan JM, Rhee JW, Drum CL, Bronson RT, Golomb G, Langer R, Farokhzad OC.

Proc Natl Acad Sci U S A. 2011 Nov 29;108(48):19347-52. doi: 10.1073/pnas.1115945108. Epub 2011 Nov 15.


Photo-response behavior of electrospun nanofibers based on spiropyran-cyclodextrin modified polymer.

De Sousa FB, Guerreiro JD, Ma M, Anderson DG, Drum CL, Sinisterra RD, Langer R.

J Mater Chem. 2010 Nov 28;20(44):9910-9917. doi: 10.1039/c0jm01903h. Epub 2010 Sep 28.


Structure of anthrax edema factor-calmodulin-adenosine 5'-(alpha,beta-methylene)-triphosphate complex reveals an alternative mode of ATP binding to the catalytic site.

Shen Y, Guo Q, Zhukovskaya NL, Drum CL, Bohm A, Tang WJ.

Biochem Biophys Res Commun. 2004 Apr 30;317(2):309-14.


Structural basis for the activation of anthrax adenylyl cyclase exotoxin by calmodulin.

Drum CL, Yan SZ, Bard J, Shen YQ, Lu D, Soelaiman S, Grabarek Z, Bohm A, Tang WJ.

Nature. 2002 Jan 24;415(6870):396-402.


Crystallization and preliminary X-ray study of the edema factor exotoxin adenylyl cyclase domain from Bacillus anthracis in the presence of its activator, calmodulin.

Drum CL, Shen Y, Rice PA, Bohm A, Tang WJ.

Acta Crystallogr D Biol Crystallogr. 2001 Dec;57(Pt 12):1881-4. Epub 2001 Nov 21.


An extended conformation of calmodulin induces interactions between the structural domains of adenylyl cyclase from Bacillus anthracis to promote catalysis.

Drum CL, Yan SZ, Sarac R, Mabuchi Y, Beckingham K, Bohm A, Grabarek Z, Tang WJ.

J Biol Chem. 2000 Nov 17;275(46):36334-40.


Class III adenylyl cyclases: regulation and underlying mechanisms.

Tang WJ, Yan S, Drum CL.

Adv Second Messenger Phosphoprotein Res. 1998;32:137-51. Review. No abstract available.


Differences in the binding sites of two site-3 sodium channel toxins.

Benzinger GR, Drum CL, Chen LQ, Kallen RG, Hanck DA, Hanck D.

Pflugers Arch. 1997 Nov;434(6):742-9.


Role for Pro-13 in directing high-affinity binding of anthopleurin B to the voltage-sensitive sodium channel.

Kelso GJ, Drum CL, Hanck DA, Blumenthal KM.

Biochemistry. 1996 Nov 12;35(45):14157-64.


The role of exposed tryptophan residues in the activity of the cardiotonic polypeptide anthopleurin B.

Dias-Kadambi BL, Combs KA, Drum CL, Hanck DA, Blumenthal KM.

J Biol Chem. 1996 Sep 27;271(39):23828-35.


Leucine 18, a hydrophobic residue essential for high affinity binding of anthopleurin B to the voltage-sensitive sodium channel.

Dias-Kadambi BL, Drum CL, Hanck DA, Blumenthal KM.

J Biol Chem. 1996 Apr 19;271(16):9422-8.


Multiple cationic residues of anthopleurin B that determine high affinity and channel isoform discrimination.

Khera PK, Benzinger GR, Lipkind G, Drum CL, Hanck DA, Blumenthal KM.

Biochemistry. 1995 Jul 11;34(27):8533-41.


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