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Items: 1 to 50 of 79

1.

Neutrophil activation in systemic capillary leak syndrome (Clarkson disease).

Xie Z, Kuhns DB, Gu X, Otu HH, Libermann TA, Gallin JI, Parikh SM, Druey KM.

J Cell Mol Med. 2019 Aug;23(8):5119-5127. doi: 10.1111/jcmm.14381. Epub 2019 Jun 18.

2.

Regulator of G-Protein Signaling 16 Is a Negative Modulator of Platelet Function and Thrombosis.

Hernandez KR, Karim ZA, Qasim H, Druey KM, Alshbool FZ, Khasawneh FT.

J Am Heart Assoc. 2019 Mar 5;8(5):e011273. doi: 10.1161/JAHA.118.011273.

3.

Whole-Exome Sequencing of Adult and Pediatric Cohorts of the Rare Vascular Disorder Systemic Capillary Leak Syndrome.

Pierce R, Ji W, Chan EC, Xie Z, Long LM, Khokha M, Lakhani S, Druey KM.

Shock. 2019 Aug;52(2):183-190. doi: 10.1097/SHK.0000000000001254.

PMID:
30289850
4.

Severe capillary leak syndrome with cardiac arrest triggered by influenza virus infection.

Ebdrup L, Druey KM, Druey K, Mogensen TH.

BMJ Case Rep. 2018 Aug 29;2018. pii: bcr-2018-226108. doi: 10.1136/bcr-2018-226108. Erratum in: BMJ Case Rep. 2018 Oct 3;2018:. Druey K [corrected to Druey KM].

5.

Regulator of G protein signaling 5 restricts neutrophil chemotaxis and trafficking.

Chan EC, Ren C, Xie Z, Jude J, Barker T, Koziol-White CA, Ma M, Panettieri RA Jr, Wu D, Rosenberg HF, Druey KM.

J Biol Chem. 2018 Aug 17;293(33):12690-12702. doi: 10.1074/jbc.RA118.002404. Epub 2018 Jun 21.

6.

Reply.

Druey KM, Arai AE, Parikh SM.

J Allergy Clin Immunol. 2018 Apr;141(4):1540-1541. doi: 10.1016/j.jaci.2017.11.054. Epub 2018 Feb 21. No abstract available.

PMID:
29477580
7.

Alternaria alternata challenge at the nasal mucosa results in eosinophilic inflammation and increased susceptibility to influenza virus infection.

Ma M, Redes JL, Percopo CM, Druey KM, Rosenberg HF.

Clin Exp Allergy. 2018 Jun;48(6):691-702. doi: 10.1111/cea.13123. Epub 2018 Apr 15.

8.

Modeling asthma: Pitfalls, promises, and the road ahead.

Rosenberg HF, Druey KM.

J Leukoc Biol. 2018 Jul;104(1):41-48. doi: 10.1002/JLB.3MR1117-436R. Epub 2018 Feb 16. Review.

9.
10.

Adrenomedullin surges are linked to acute episodes of the systemic capillary leak syndrome (Clarkson disease).

Xie Z, Chen WS, Yin Y, Chan EC, Terai K, Long LM, Myers TG, Dudek AZ, Druey KM.

J Leukoc Biol. 2018 Apr;103(4):749-759. doi: 10.1002/JLB.5A0817-324R. Epub 2018 Jan 23.

11.

Editorial: Stressing out mast cells via CRF1.

Lyons JJ, Rosenberg HF, Druey KM.

J Leukoc Biol. 2017 Dec;102(6):1284-1285. doi: 10.1189/jlb.2CE0617-248RR. No abstract available.

PMID:
29191866
12.

Emerging Roles of Regulators of G Protein Signaling (RGS) Proteins in the Immune System.

Druey KM.

Adv Immunol. 2017;136:315-351. doi: 10.1016/bs.ai.2017.05.001. Epub 2017 May 29. Review.

PMID:
28950950
13.

Aspergillus fumigatus alkaline protease 1 (Alp1/Asp f13) in the airways correlates with asthma severity.

Basu T, Seyedmousavi S, Sugui JA, Balenga N, Zhao M, Kwon Chung KJ, Biardel S, Laviolette M, Druey KM.

J Allergy Clin Immunol. 2018 Jan;141(1):423-425.e7. doi: 10.1016/j.jaci.2017.07.034. Epub 2017 Sep 4. No abstract available.

14.

RGS4 Overexpression in Lung Attenuates Airway Hyperresponsiveness in Mice.

Madigan LA, Wong GS, Gordon EM, Chen WS, Balenga N, Koziol-White CJ, Panettieri RA Jr, Levine SJ, Druey KM.

Am J Respir Cell Mol Biol. 2018 Jan;58(1):89-98. doi: 10.1165/rcmb.2017-0109OC.

15.

Idiopathic systemic capillary leak syndrome (Clarkson disease).

Druey KM, Parikh SM.

J Allergy Clin Immunol. 2017 Sep;140(3):663-670. doi: 10.1016/j.jaci.2016.10.042. Epub 2016 Dec 22. Review.

16.

RGS10 Negatively Regulates Platelet Activation and Thrombogenesis.

Hensch NR, Karim ZA, Druey KM, Tansey MG, Khasawneh FT.

PLoS One. 2016 Nov 9;11(11):e0165984. doi: 10.1371/journal.pone.0165984. eCollection 2016.

17.

Eosinophils, galectins, and a reason to breathe.

Rosenberg HF, Druey KM.

Proc Natl Acad Sci U S A. 2016 Aug 16;113(33):9139-41. doi: 10.1073/pnas.1610644113. Epub 2016 Aug 5. No abstract available.

18.

CXCL12 regulates platelet activation via the regulator of G-protein signaling 16.

Karim ZA, Alshbool FZ, Vemana HP, Conlon C, Druey KM, Khasawneh FT.

Biochim Biophys Acta. 2016 Feb;1863(2):314-21. doi: 10.1016/j.bbamcr.2015.11.028. Epub 2015 Nov 25.

19.

R4 Regulator of G Protein Signaling (RGS) Proteins in Inflammation and Immunity.

Xie Z, Chan EC, Druey KM.

AAPS J. 2016 Mar;18(2):294-304. doi: 10.1208/s12248-015-9847-0. Epub 2015 Nov 23. Review.

20.

Correction: Endothelial Expression of Endothelin Receptor A in the Systemic Capillary Leak Syndrome.

Sek AC, Xie Z, Terai K, Long LM, Nelson C, Dudek AZ, Druey KM.

PLoS One. 2015 Sep 1;10(9):e0137373. doi: 10.1371/journal.pone.0137373. eCollection 2015. No abstract available.

21.

Increased myocardial extracellular volume in active idiopathic systemic capillary leak syndrome.

Ertel A, Pratt D, Kellman P, Leung S, Bandettini P, Long LM, Young M, Nelson C, Arai AE, Druey KM.

J Cardiovasc Magn Reson. 2015 Aug 27;17:76. doi: 10.1186/s12968-015-0181-6.

22.

Endothelial Expression of Endothelin Receptor A in the Systemic Capillary Leak Syndrome.

Sek AC, Xie Z, Terai K, Long LM, Nelson C, Dudek AZ, Druey KM.

PLoS One. 2015 Jul 15;10(7):e0133266. doi: 10.1371/journal.pone.0133266. eCollection 2015. Erratum in: PLoS One. 2015;10(9):e0137373.

23.

A fungal protease allergen provokes airway hyper-responsiveness in asthma.

Balenga NA, Klichinsky M, Xie Z, Chan EC, Zhao M, Jude J, Laviolette M, Panettieri RA Jr, Druey KM.

Nat Commun. 2015 Apr 13;6:6763. doi: 10.1038/ncomms7763.

24.

Idiopathic systemic capillary leak syndrome in children.

Hsu P, Xie Z, Frith K, Wong M, Kakakios A, Stone KD, Druey KM.

Pediatrics. 2015 Mar;135(3):e730-5. doi: 10.1542/peds.2014-2268.

25.

Eosinophil-associated ribonuclease 11 is a macrophage chemoattractant.

Yamada KJ, Barker T, Dyer KD, Rice TA, Percopo CM, Garcia-Crespo KE, Cho S, Lee JJ, Druey KM, Rosenberg HF.

J Biol Chem. 2015 Apr 3;290(14):8863-75. doi: 10.1074/jbc.M114.626648. Epub 2015 Feb 20.

26.

Inflammatory Markers of the Systemic Capillary Leak Syndrome (Clarkson Disease).

Xie Z, Chan E, Yin Y, Ghosh CC, Wisch L, Nelson C, Young M, Parikh SM, Druey KM.

J Clin Cell Immunol. 2014;5:1000213.

27.

High-dose intravenous immunoglobulin therapy for systemic capillary leak syndrome (Clarkson disease).

Xie Z, Chan EC, Long LM, Nelson C, Druey KM.

Am J Med. 2015 Jan;128(1):91-5. doi: 10.1016/j.amjmed.2014.08.015. Epub 2014 Sep 3.

28.

Genome-wide SNP analysis of the Systemic Capillary Leak Syndrome (Clarkson disease).

Xie Z, Nagarajan V, Sturdevant DE, Iwaki S, Chan E, Wisch L, Young M, Nelson CM, Porcella SF, Druey KM.

Rare Dis. 2013 Dec 12;1(1). pii: e27445.

29.

Mechanistic classification of the systemic capillary leak syndrome: Clarkson disease.

Xie Z, Ghosh CC, Parikh SM, Druey KM.

Am J Respir Crit Care Med. 2014 May 1;189(9):1145-7. doi: 10.1164/rccm.201310-1746LE. No abstract available.

30.

Loss of regulator of G protein signaling 5 promotes airway hyperresponsiveness in the absence of allergic inflammation.

Balenga NA, Jester W, Jiang M, Panettieri RA Jr, Druey KM.

J Allergy Clin Immunol. 2014 Aug;134(2):451-9. doi: 10.1016/j.jaci.2014.01.019. Epub 2014 Mar 22.

31.

IL-17RA is essential for optimal localization of follicular Th cells in the germinal center light zone to promote autoantibody-producing B cells.

Ding Y, Li J, Wu Q, Yang P, Luo B, Xie S, Druey KM, Zajac AJ, Hsu HC, Mountz JD.

J Immunol. 2013 Aug 15;191(4):1614-24. doi: 10.4049/jimmunol.1300479. Epub 2013 Jul 15.

32.

Extension of the germinal center stage of B cell development promotes autoantibodies in BXD2 mice.

Wang JH, New JS, Xie S, Yang P, Wu Q, Li J, Luo B, Ding Y, Druey KM, Hsu HC, Mountz JD.

Arthritis Rheum. 2013 Oct;65(10):2703-12. doi: 10.1002/art.38059.

33.

Enhanced effector function of CD8(+) T cells from healthy controls and HIV-infected patients occurs through thrombin activation of protease-activated receptor 1.

Hurley A, Smith M, Karpova T, Hasley RB, Belkina N, Shaw S, Balenga N, Druey KM, Nickel E, Packard B, Imamichi H, Hu Z, Follmann D, McNally J, Higgins J, Sneller M, Lane HC, Catalfamo M.

J Infect Dis. 2013 Feb 15;207(4):638-50. doi: 10.1093/infdis/jis730. Epub 2012 Nov 29.

34.

Extracellular volume fraction mapping in the myocardium, part 2: initial clinical experience.

Kellman P, Wilson JR, Xue H, Bandettini WP, Shanbhag SM, Druey KM, Ugander M, Arai AE.

J Cardiovasc Magn Reson. 2012 Sep 11;14:64. doi: 10.1186/1532-429X-14-64.

35.

RGS16 attenuates pulmonary Th2/Th17 inflammatory responses.

Shankar SP, Wilson MS, DiVietro JA, Mentink-Kane MM, Xie Z, Wynn TA, Druey KM.

J Immunol. 2012 Jun 15;188(12):6347-56. doi: 10.4049/jimmunol.1103781. Epub 2012 May 16.

36.

RGS10 exerts a neuroprotective role through the PKA/c-AMP response-element (CREB) pathway in dopaminergic neuron-like cells.

Lee JK, Chung J, Druey KM, Tansey MG.

J Neurochem. 2012 Jul;122(2):333-43. doi: 10.1111/j.1471-4159.2012.07780.x. Epub 2012 May 30.

37.

Naive T cells sense the cysteine protease allergen papain through protease-activated receptor 2 and propel TH2 immunity.

Liang G, Barker T, Xie Z, Charles N, Rivera J, Druey KM.

J Allergy Clin Immunol. 2012 May;129(5):1377-1386.e13. doi: 10.1016/j.jaci.2012.02.035. Epub 2012 Mar 27.

38.

Vascular endothelial hyperpermeability induces the clinical symptoms of Clarkson disease (the systemic capillary leak syndrome).

Xie Z, Ghosh CC, Patel R, Iwaki S, Gaskins D, Nelson C, Jones N, Greipp PR, Parikh SM, Druey KM.

Blood. 2012 May 3;119(18):4321-32. doi: 10.1182/blood-2011-08-375816. Epub 2012 Mar 12.

39.

Regulator of G-protein signaling-5 inhibits bronchial smooth muscle contraction in severe asthma.

Yang Z, Balenga N, Cooper PR, Damera G, Edwards R, Brightling CE, Panettieri RA Jr, Druey KM.

Am J Respir Cell Mol Biol. 2012 Jun;46(6):823-32. doi: 10.1165/rcmb.2011-0110OC. Epub 2012 Jan 26.

40.

An RGS4-mediated phenotypic switch of bronchial smooth muscle cells promotes fixed airway obstruction in asthma.

Damera G, Druey KM, Cooper PR, Krymskaya VP, Soberman RJ, Amrani Y, Hoshi T, Brightling CE, Panettieri RA Jr.

PLoS One. 2012;7(1):e28504. doi: 10.1371/journal.pone.0028504. Epub 2012 Jan 12.

41.

p53 negatively regulates RGS13 protein expression in immune cells.

Iwaki S, Lu Y, Xie Z, Druey KM.

J Biol Chem. 2011 Jun 24;286(25):22219-26. doi: 10.1074/jbc.M111.228924. Epub 2011 Apr 29.

42.

Regulator of G protein signaling 5 is highly expressed in parathyroid tumors and inhibits signaling by the calcium-sensing receptor.

Koh J, Dar M, Untch BR, Dixit D, Shi Y, Yang Z, Adam MA, Dressman H, Wang X, Gesty-Palmer D, Marks JR, Spurney R, Druey KM, Olson JA Jr.

Mol Endocrinol. 2011 May;25(5):867-76. doi: 10.1210/me.2010-0277. Epub 2011 Mar 10.

43.

Beta-agonist-associated reduction in RGS5 expression promotes airway smooth muscle hyper-responsiveness.

Yang Z, Cooper PR, Damera G, Mukhopadhyay I, Cho H, Kehrl JH, Panettieri RA Jr, Druey KM.

J Biol Chem. 2011 Apr 1;286(13):11444-55. doi: 10.1074/jbc.M110.212480. Epub 2011 Jan 29.

44.

Phosphorylation of RGS13 by the cyclic AMP-dependent protein kinase inhibits RGS13 degradation.

Xie Z, Yang Z, Druey KM.

J Mol Cell Biol. 2010 Dec;2(6):357-65. doi: 10.1093/jmcb/mjq031. Epub 2010 Oct 25.

45.

Narrative review: the systemic capillary leak syndrome.

Druey KM, Greipp PR.

Ann Intern Med. 2010 Jul 20;153(2):90-8. doi: 10.7326/0003-4819-153-2-201007200-00005. Review.

46.

Mouse and human eosinophils degranulate in response to platelet-activating factor (PAF) and lysoPAF via a PAF-receptor-independent mechanism: evidence for a novel receptor.

Dyer KD, Percopo CM, Xie Z, Yang Z, Kim JD, Davoine F, Lacy P, Druey KM, Moqbel R, Rosenberg HF.

J Immunol. 2010 Jun 1;184(11):6327-34. doi: 10.4049/jimmunol.0904043. Epub 2010 Apr 26.

47.

RGS16 inhibits breast cancer cell growth by mitigating phosphatidylinositol 3-kinase signaling.

Liang G, Bansal G, Xie Z, Druey KM.

J Biol Chem. 2009 Aug 7;284(32):21719-27. doi: 10.1074/jbc.M109.028407. Epub 2009 Jun 9.

48.

RGS13 controls g protein-coupled receptor-evoked responses of human mast cells.

Bansal G, DiVietro JA, Kuehn HS, Rao S, Nocka KH, Gilfillan AM, Druey KM.

J Immunol. 2008 Dec 1;181(11):7882-90.

49.

Regulation of G-protein-coupled signaling pathways in allergic inflammation.

Druey KM.

Immunol Res. 2009;43(1-3):62-76. doi: 10.1007/s12026-008-8050-0. Review.

50.

RGS13 acts as a nuclear repressor of CREB.

Xie Z, Geiger TR, Johnson EN, Nyborg JK, Druey KM.

Mol Cell. 2008 Sep 5;31(5):660-70. doi: 10.1016/j.molcel.2008.06.024.

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