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Items: 15

1.

CRISPR-Knockout Screen Identifies Dmap1 as a Regulator of Chemically Induced Reprogramming and Differentiation of Cardiac Progenitors.

Yu JSL, Palano G, Lim C, Moggio A, Drowley L, Plowright AT, Bohlooly-Y M, Rosen BS, Hansson EM, Wang QD, Yusa K.

Stem Cells. 2019 Apr 1. doi: 10.1002/stem.3012. [Epub ahead of print]

PMID:
30932271
2.

Drug Screening in Human PSC-Cardiac Organoids Identifies Pro-proliferative Compounds Acting via the Mevalonate Pathway.

Mills RJ, Parker BL, Quaife-Ryan GA, Voges HK, Needham EJ, Bornot A, Ding M, Andersson H, Polla M, Elliott DA, Drowley L, Clausen M, Plowright AT, Barrett IP, Wang QD, James DE, Porrello ER, Hudson JE.

Cell Stem Cell. 2019 Jun 6;24(6):895-907.e6. doi: 10.1016/j.stem.2019.03.009. Epub 2019 Mar 28.

PMID:
30930147
3.

Toward Second-Generation Cardiomyogenic and Anti-cardiofibrotic 1,4-Dihydropyridine-Class TGFβ Inhibitors.

Längle D, Werner TR, Wesseler F, Reckzeh E, Schaumann N, Drowley L, Polla M, Plowright AT, Hirt MN, Eschenhagen T, Schade D.

ChemMedChem. 2019 Apr 17;14(8):810-822. doi: 10.1002/cmdc.201900036. Epub 2019 Feb 28.

PMID:
30768867
4.

High-content phenotypic assay for proliferation of human iPSC-derived cardiomyocytes identifies L-type calcium channels as targets.

Woo LA, Tkachenko S, Ding M, Plowright AT, Engkvist O, Andersson H, Drowley L, Barrett I, Firth M, Akerblad P, Wolf MJ, Bekiranov S, Brautigan DL, Wang QD, Saucerman JJ.

J Mol Cell Cardiol. 2019 Feb;127:204-214. doi: 10.1016/j.yjmcc.2018.12.015. Epub 2018 Dec 28.

PMID:
30597148
5.

Functional screening in human cardiac organoids reveals a metabolic mechanism for cardiomyocyte cell cycle arrest.

Mills RJ, Titmarsh DM, Koenig X, Parker BL, Ryall JG, Quaife-Ryan GA, Voges HK, Hodson MP, Ferguson C, Drowley L, Plowright AT, Needham EJ, Wang QD, Gregorevic P, Xin M, Thomas WG, Parton RG, Nielsen LK, Launikonis BS, James DE, Elliott DA, Porrello ER, Hudson JE.

Proc Natl Acad Sci U S A. 2017 Oct 3;114(40):E8372-E8381. doi: 10.1073/pnas.1707316114. Epub 2017 Sep 15.

6.

Phenotypic Screen for Cardiac Regeneration Identifies Molecules with Differential Activity in Human Epicardium-Derived Cells versus Cardiac Fibroblasts.

Paunovic AI, Drowley L, Nordqvist A, Ericson E, Mouchet E, Jonebring A, Grönberg G, Kvist AJ, Engkvist O, Brown MR, Gedda K, Goumans MJ, Wang QD, Plowright AT.

ACS Chem Biol. 2017 Jan 20;12(1):132-141. doi: 10.1021/acschembio.6b00683. Epub 2016 Nov 30.

PMID:
28103692
7.

Comparative transcriptomic analysis identifies genes differentially expressed in human epicardial progenitors and hiPSC-derived cardiac progenitors.

Synnergren J, Drowley L, Plowright AT, Brolén G, Goumans MJ, Gittenberger-de Groot AC, Sartipy P, Wang QD.

Physiol Genomics. 2016 Nov 1;48(11):771-784. doi: 10.1152/physiolgenomics.00064.2016. Epub 2016 Sep 2.

8.

Long-term self-renewing human epicardial cells generated from pluripotent stem cells under defined xeno-free conditions.

Bao X, Lian X, Hacker TA, Schmuck EG, Qian T, Bhute VJ, Han T, Shi M, Drowley L, Plowright A, Wang QD, Goumans MJ, Palecek SP.

Nat Biomed Eng. 2016;1. pii: 0003. doi: 10.1038/s41551-016-0003. Epub 2016 Dec 5.

9.

Human Induced Pluripotent Stem Cell-Derived Cardiac Progenitor Cells in Phenotypic Screening: A Transforming Growth Factor-β Type 1 Receptor Kinase Inhibitor Induces Efficient Cardiac Differentiation.

Drowley L, Koonce C, Peel S, Jonebring A, Plowright AT, Kattman SJ, Andersson H, Anson B, Swanson BJ, Wang QD, Brolen G.

Stem Cells Transl Med. 2016 Feb;5(2):164-74. doi: 10.5966/sctm.2015-0114. Epub 2015 Dec 18.

10.

Human myogenic endothelial cells exhibit chondrogenic and osteogenic potentials at the clonal level.

Zheng B, Li G, Chen WC, Deasy BM, Pollett JB, Sun B, Drowley L, Gharaibeh B, Usas A, Péault B, Huard J.

J Orthop Res. 2013 Jul;31(7):1089-95. doi: 10.1002/jor.22335. Epub 2013 Apr 1.

11.

Mechanical loading of stem cells for improvement of transplantation outcome in a model of acute myocardial infarction: the role of loading history.

Cassino TR, Drowley L, Okada M, Beckman SA, Keller B, Tobita K, Leduc PR, Huard J.

Tissue Eng Part A. 2012 Jun;18(11-12):1101-8. doi: 10.1089/ten.TEA.2011.0285. Epub 2012 Mar 7.

12.

Human skeletal muscle cells with a slow adhesion rate after isolation and an enhanced stress resistance improve function of ischemic hearts.

Okada M, Payne TR, Drowley L, Jankowski RJ, Momoi N, Beckman S, Chen WC, Keller BB, Tobita K, Huard J.

Mol Ther. 2012 Jan;20(1):138-45. doi: 10.1038/mt.2011.229. Epub 2011 Nov 8.

13.

Cellular antioxidant levels influence muscle stem cell therapy.

Drowley L, Okada M, Beckman S, Vella J, Keller B, Tobita K, Huard J.

Mol Ther. 2010 Oct;18(10):1865-73. doi: 10.1038/mt.2010.160. Epub 2010 Jul 27.

14.

Sex of muscle stem cells does not influence potency for cardiac cell therapy.

Drowley L, Okada M, Payne TR, Botta GP, Oshima H, Keller BB, Tobita K, Huard J.

Cell Transplant. 2009;18(10):1137-46. doi: 10.3727/096368909X471305. Epub 2009 May 6.

PMID:
19523348
15.

Prospective identification of myogenic endothelial cells in human skeletal muscle.

Zheng B, Cao B, Crisan M, Sun B, Li G, Logar A, Yap S, Pollett JB, Drowley L, Cassino T, Gharaibeh B, Deasy BM, Huard J, Péault B.

Nat Biotechnol. 2007 Sep;25(9):1025-34. Epub 2007 Sep 2.

PMID:
17767154

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