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Items: 30

1.

Toxicological and pharmacological assessment of AGEN1884, a novel human IgG1 anti-CTLA-4 antibody.

Gombos RB, Gonzalez A, Manrique M, Chand D, Savitsky D, Morin B, Breous-Nystrom E, Dupont C, Ward RA, Mundt C, Duckless B, Tang H, Findeis MA, Schuster A, Waight JD, Underwood D, Clarke C, Ritter G, Merghoub T, Schaer D, Wolchok JD, van Dijk M, Buell JS, Cuillerot JM, Stein R, Drouin EE, Wilson NS.

PLoS One. 2018 Apr 4;13(4):e0191926. doi: 10.1371/journal.pone.0191926. eCollection 2018.

2.

Two rheumatoid arthritis-specific autoantigens correlate microbial immunity with autoimmune responses in joints.

Pianta A, Arvikar SL, Strle K, Drouin EE, Wang Q, Costello CE, Steere AC.

J Clin Invest. 2017 Aug 1;127(8):2946-2956. doi: 10.1172/JCI93450. Epub 2017 Jun 26.

3.

Evidence of the Immune Relevance of Prevotella copri, a Gut Microbe, in Patients With Rheumatoid Arthritis.

Pianta A, Arvikar S, Strle K, Drouin EE, Wang Q, Costello CE, Steere AC.

Arthritis Rheumatol. 2017 May;69(5):964-975. doi: 10.1002/art.40003. Epub 2017 Apr 7.

4.

Immunogenic HLA-DR-Presented Self-Peptides Identified Directly from Clinical Samples of Synovial Tissue, Synovial Fluid, or Peripheral Blood in Patients with Rheumatoid Arthritis or Lyme Arthritis.

Wang Q, Drouin EE, Yao C, Zhang J, Huang Y, Leon DR, Steere AC, Costello CE.

J Proteome Res. 2017 Jan 6;16(1):122-136. doi: 10.1021/acs.jproteome.6b00386. Epub 2016 Nov 7.

5.

Matrix metalloproteinase-10 is a target of T and B cell responses that correlate with synovial pathology in patients with antibiotic-refractory Lyme arthritis.

Crowley JT, Strle K, Drouin EE, Pianta A, Arvikar SL, Wang Q, Costello CE, Steere AC.

J Autoimmun. 2016 May;69:24-37. doi: 10.1016/j.jaut.2016.02.005. Epub 2016 Feb 26.

6.

Annexin A2 is a target of autoimmune T and B cell responses associated with synovial fibroblast proliferation in patients with antibiotic-refractory Lyme arthritis.

Pianta A, Drouin EE, Crowley JT, Arvikar S, Strle K, Costello CE, Steere AC.

Clin Immunol. 2015 Oct;160(2):336-41. doi: 10.1016/j.clim.2015.07.005. Epub 2015 Jul 15.

7.

A Highly Expressed Human Protein, Apolipoprotein B-100, Serves as an Autoantigen in a Subgroup of Patients With Lyme Disease.

Crowley JT, Drouin EE, Pianta A, Strle K, Wang Q, Costello CE, Steere AC.

J Infect Dis. 2015 Dec 1;212(11):1841-50. doi: 10.1093/infdis/jiv310. Epub 2015 May 26.

8.

Reply to Seligman et Al.

Strle K, Stupica D, Drouin EE, Steere AC, Strle F.

Clin Infect Dis. 2014 Sep 1;59(5):747-8. doi: 10.1093/cid/ciu343. Epub 2014 May 7. No abstract available.

PMID:
24812297
9.

Antibodies to endothelial cell growth factor and obliterative microvascular lesions in the synovium of patients with antibiotic-refractory lyme arthritis.

Londoño D, Cadavid D, Drouin EE, Strle K, McHugh G, Aversa JM, Steere AC.

Arthritis Rheumatol. 2014 Aug;66(8):2124-33. doi: 10.1002/art.38618.

10.

Reply to Parvu and Parvu.

Strle K, Stupica D, Drouin EE, Steere AC, Strle F.

Clin Infect Dis. 2014 Apr;58(8):1200. doi: 10.1093/cid/ciu062. Epub 2014 Jan 26. No abstract available.

PMID:
24470277
11.

Natural killer cells and natural killer T cells in Lyme arthritis.

Katchar K, Drouin EE, Steere AC.

Arthritis Res Ther. 2013 Nov 7;15(6):R183. doi: 10.1186/ar4373.

12.

Elevated levels of IL-23 in a subset of patients with post-lyme disease symptoms following erythema migrans.

Strle K, Stupica D, Drouin EE, Steere AC, Strle F.

Clin Infect Dis. 2014 Feb;58(3):372-80. doi: 10.1093/cid/cit735. Epub 2013 Nov 11.

13.

Dysregulation of CD4+CD25(high) T cells in the synovial fluid of patients with antibiotic-refractory Lyme arthritis.

Vudattu NK, Strle K, Steere AC, Drouin EE.

Arthritis Rheum. 2013 Jun;65(6):1643-53. doi: 10.1002/art.37910.

14.

A novel human autoantigen, endothelial cell growth factor, is a target of T and B cell responses in patients with Lyme disease.

Drouin EE, Seward RJ, Strle K, McHugh G, Katchar K, Londoño D, Yao C, Costello CE, Steere AC.

Arthritis Rheum. 2013 Jan;65(1):186-96. doi: 10.1002/art.37732.

15.

Borrelia burgdorferi RST1 (OspC type A) genotype is associated with greater inflammation and more severe Lyme disease.

Strle K, Jones KL, Drouin EE, Li X, Steere AC.

Am J Pathol. 2011 Jun;178(6):2726-39. doi: 10.1016/j.ajpath.2011.02.018.

16.

Relationship between immunity to Borrelia burgdorferi outer-surface protein A (OspA) and Lyme arthritis.

Steere AC, Drouin EE, Glickstein LJ.

Clin Infect Dis. 2011 Feb;52 Suppl 3:s259-65. doi: 10.1093/cid/ciq117. Review.

17.

Peptides presented by HLA-DR molecules in synovia of patients with rheumatoid arthritis or antibiotic-refractory Lyme arthritis.

Seward RJ, Drouin EE, Steere AC, Costello CE.

Mol Cell Proteomics. 2011 Mar;10(3):M110.002477. doi: 10.1074/mcp.M110.002477. Epub 2010 Nov 16.

18.

Treg cell numbers and function in patients with antibiotic-refractory or antibiotic-responsive Lyme arthritis.

Shen S, Shin JJ, Strle K, McHugh G, Li X, Glickstein LJ, Drouin EE, Steere AC.

Arthritis Rheum. 2010 Jul;62(7):2127-37. doi: 10.1002/art.27468.

19.

Borrelia burgdorferi stimulates macrophages to secrete higher levels of cytokines and chemokines than Borrelia afzelii or Borrelia garinii.

Strle K, Drouin EE, Shen S, El Khoury J, McHugh G, Ruzic-Sabljic E, Strle F, Steere AC.

J Infect Dis. 2009 Dec 15;200(12):1936-43. doi: 10.1086/648091.

20.

Searching for borrelial T cell epitopes associated with antibiotic-refractory Lyme arthritis.

Drouin EE, Glickstein L, Kwok WW, Nepom GT, Steere AC.

Mol Immunol. 2008 Apr;45(8):2323-32. doi: 10.1016/j.molimm.2007.11.010. Epub 2008 Jan 11. Erratum in: Mol Immunol. 2008 Jul;45(12):3508.

22.

Human homologues of a Borrelia T cell epitope associated with antibiotic-refractory Lyme arthritis.

Drouin EE, Glickstein L, Kwok WW, Nepom GT, Steere AC.

Mol Immunol. 2008 Jan;45(1):180-9. Epub 2007 Jun 6.

23.

Antibiotic-refractory Lyme arthritis is associated with HLA-DR molecules that bind a Borrelia burgdorferi peptide.

Steere AC, Klitz W, Drouin EE, Falk BA, Kwok WW, Nepom GT, Baxter-Lowe LA.

J Exp Med. 2006 Apr 17;203(4):961-71. Epub 2006 Apr 3.

24.

Human Lyme arthritis and the immunoglobulin G antibody response to the 37-kilodalton arthritis-related protein of Borrelia burgdorferi.

Salazar CA, Rothemich M, Drouin EE, Glickstein L, Steere AC.

Infect Immun. 2005 May;73(5):2951-7.

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The major, N2-Gua adduct of the (+)-anti-benzo[a]pyrene diol epoxide can be unstable in double-stranded DNA.

Drouin EE, Lech J, Loechler EL.

Biochemistry. 1995 Feb 21;34(7):2251-9.

PMID:
7857936
30.

Meiotic instability of tandemly iterated plasmid sequences in the yeast chromosome.

Denis CL, Drouin EE.

Curr Genet. 1987;12(6):399-403.

PMID:
3329054

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