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Items: 1 to 50 of 194

1.

Heat activation of TRPM5 underlies thermal sensitivity of sweet taste.

Talavera K, Yasumatsu K, Voets T, Droogmans G, Shigemura N, Ninomiya Y, Margolskee RF, Nilius B.

Nature. 2005 Dec 15;438(7070):1022-5.

PMID:
16355226
2.

Gating of TRP channels: a voltage connection?

Nilius B, Talavera K, Owsianik G, Prenen J, Droogmans G, Voets T.

J Physiol. 2005 Aug 15;567(Pt 1):35-44. Epub 2005 May 5. Review.

3.

Comparison of functional properties of the Ca2+-activated cation channels TRPM4 and TRPM5 from mice.

Ullrich ND, Voets T, Prenen J, Vennekens R, Talavera K, Droogmans G, Nilius B.

Cell Calcium. 2005 Mar;37(3):267-78.

PMID:
15670874
4.

Invertebrate TRP proteins as functional models for mammalian channels.

Vriens J, Owsianik G, Voets T, Droogmans G, Nilius B.

Pflugers Arch. 2004 Dec;449(3):213-26. Review.

PMID:
15480752
5.

Decavanadate modulates gating of TRPM4 cation channels.

Nilius B, Prenen J, Janssens A, Voets T, Droogmans G.

J Physiol. 2004 Nov 1;560(Pt 3):753-65. Epub 2004 Aug 26.

6.

Mechanism of arachidonic acid modulation of the T-type Ca2+ channel alpha1G.

Talavera K, Staes M, Janssens A, Droogmans G, Nilius B.

J Gen Physiol. 2004 Sep;124(3):225-38. Epub 2004 Aug 16.

7.

The principle of temperature-dependent gating in cold- and heat-sensitive TRP channels.

Voets T, Droogmans G, Wissenbach U, Janssens A, Flockerzi V, Nilius B.

Nature. 2004 Aug 12;430(7001):748-54.

PMID:
15306801
8.

[ATP release pathways in vascular endothelial cells].

Oike M, Droogmans G, Ito Y.

Nihon Yakurigaku Zasshi. 2004 Jun;123(6):403-11. Review. Japanese.

PMID:
15170080
9.

Intracellular nucleotides and polyamines inhibit the Ca2+-activated cation channel TRPM4b.

Nilius B, Prenen J, Voets T, Droogmans G.

Pflugers Arch. 2004 Apr;448(1):70-5. Epub 2004 Jan 31.

PMID:
14758478
10.

Outer pore architecture of a Ca2+-selective TRP channel.

Voets T, Janssens A, Droogmans G, Nilius B.

J Biol Chem. 2004 Apr 9;279(15):15223-30. Epub 2004 Jan 21.

11.

TRPV4 calcium entry channel: a paradigm for gating diversity.

Nilius B, Vriens J, Prenen J, Droogmans G, Voets T.

Am J Physiol Cell Physiol. 2004 Feb;286(2):C195-205. Review.

12.

Cell swelling, heat, and chemical agonists use distinct pathways for the activation of the cation channel TRPV4.

Vriens J, Watanabe H, Janssens A, Droogmans G, Voets T, Nilius B.

Proc Natl Acad Sci U S A. 2004 Jan 6;101(1):396-401. Epub 2003 Dec 22.

13.

Cell volume response to hyposmotic shock and elevated cAMP in bovine trabecular meshwork cells.

Srinivas SP, Maertens C, Goon LH, Goon L, Satpathy M, Yue BY, Droogmans G, Nilius B.

Exp Eye Res. 2004 Jan;78(1):15-26.

PMID:
14667824
14.

TRPM6 forms the Mg2+ influx channel involved in intestinal and renal Mg2+ absorption.

Voets T, Nilius B, Hoefs S, van der Kemp AW, Droogmans G, Bindels RJ, Hoenderop JG.

J Biol Chem. 2004 Jan 2;279(1):19-25. Epub 2003 Oct 23.

15.

Anandamide and arachidonic acid use epoxyeicosatrienoic acids to activate TRPV4 channels.

Watanabe H, Vriens J, Prenen J, Droogmans G, Voets T, Nilius B.

Nature. 2003 Jul 24;424(6947):434-8.

PMID:
12879072
16.

Voltage dependence of the Ca2+-activated cation channel TRPM4.

Nilius B, Prenen J, Droogmans G, Voets T, Vennekens R, Freichel M, Wissenbach U, Flockerzi V.

J Biol Chem. 2003 Aug 15;278(33):30813-20. Epub 2003 Jun 10.

17.

Modulation of TRPV4 gating by intra- and extracellular Ca2+.

Watanabe H, Vriens J, Janssens A, Wondergem R, Droogmans G, Nilius B.

Cell Calcium. 2003 May-Jun;33(5-6):489-95.

PMID:
12765694
18.

Extracellular Ca2+ modulates the effects of protons on gating and conduction properties of the T-type Ca2+ channel alpha1G (CaV3.1).

Talavera K, Janssens A, Klugbauer N, Droogmans G, Nilius B.

J Gen Physiol. 2003 Jun;121(6):511-28. Epub 2003 May 12.

19.

Pore structure influences gating properties of the T-type Ca2+ channel alpha1G.

Talavera K, Janssens A, Klugbauer N, Droogmans G, Nilius B.

J Gen Physiol. 2003 Jun;121(6):529-40. Epub 2003 May 12.

20.

Transient receptor potential channels in endothelium: solving the calcium entry puzzle?

Nilius B, Droogmans G, Wondergem R.

Endothelium. 2003;10(1):5-15. Review.

PMID:
12699072
21.

The carboxyl terminus of the epithelial Ca(2+) channel ECaC1 is involved in Ca(2+)-dependent inactivation.

Nilius B, Weidema F, Prenen J, Hoenderop JG, Vennekens R, Hoefs S, Droogmans G, Bindels RJ.

Pflugers Arch. 2003 Feb;445(5):584-8. Epub 2002 Nov 21.

PMID:
12634930
22.

Mg2+-dependent gating and strong inward rectification of the cation channel TRPV6.

Voets T, Janssens A, Prenen J, Droogmans G, Nilius B.

J Gen Physiol. 2003 Mar;121(3):245-60.

23.

Amazing chloride channels: an overview.

Nilius B, Droogmans G.

Acta Physiol Scand. 2003 Feb;177(2):119-47. Review.

PMID:
12558550
24.

Heat-evoked activation of TRPV4 channels in a HEK293 cell expression system and in native mouse aorta endothelial cells.

Watanabe H, Vriens J, Suh SH, Benham CD, Droogmans G, Nilius B.

J Biol Chem. 2002 Dec 6;277(49):47044-51. Epub 2002 Sep 26.

25.

Block of volume-regulated anion channels by selective serotonin reuptake inhibitors.

Maertens C, Droogmans G, Verbesselt R, Nilius B.

Naunyn Schmiedebergs Arch Pharmacol. 2002 Aug;366(2):158-65. Epub 2002 May 25.

PMID:
12122503
26.

ATP and nitric oxide modulate a Ca(2+)-activated non-selective cation current in macrovascular endothelial cells.

Suh SH, Watanabe H, Droogmans G, Nilius B.

Pflugers Arch. 2002 Jun;444(3):438-45. Epub 2002 Mar 29.

PMID:
12111254
27.

Current understanding of mammalian TRP homologues.

Vennekens R, Voets T, Bindels RJ, Droogmans G, Nilius B.

Cell Calcium. 2002 Jun;31(6):253-64. Review.

PMID:
12098215
28.

Molecular determinants of permeation through the cation channel TRPV4.

Voets T, Prenen J, Vriens J, Watanabe H, Janssens A, Wissenbach U, Bödding M, Droogmans G, Nilius B.

J Biol Chem. 2002 Sep 13;277(37):33704-10. Epub 2002 Jul 1.

29.

Fast and slow inactivation kinetics of the Ca2+ channels ECaC1 and ECaC2 (TRPV5 and TRPV6). Role of the intracellular loop located between transmembrane segments 2 and 3.

Nilius B, Prenen J, Hoenderop JG, Vennekens R, Hoefs S, Weidema AF, Droogmans G, Bindels RJ.

J Biol Chem. 2002 Aug 23;277(34):30852-8. Epub 2002 Jun 19.

30.

RhoA exerts a permissive effect on volume-regulated anion channels in vascular endothelial cells.

Carton I, Trouet D, Hermans D, Barth H, Aktories K, Droogmans G, Jorgensen NK, Hoffmann EK, Nilius B, Eggermont J.

Am J Physiol Cell Physiol. 2002 Jul;283(1):C115-25.

31.

Volume-regulated anion channels serve as an auto/paracrine nucleotide release pathway in aortic endothelial cells.

Hisadome K, Koyama T, Kimura C, Droogmans G, Ito Y, Oike M.

J Gen Physiol. 2002 Jun;119(6):511-20.

32.

Activation of TRPV4 channels (hVRL-2/mTRP12) by phorbol derivatives.

Watanabe H, Davis JB, Smart D, Jerman JC, Smith GD, Hayes P, Vriens J, Cairns W, Wissenbach U, Prenen J, Flockerzi V, Droogmans G, Benham CD, Nilius B.

J Biol Chem. 2002 Apr 19;277(16):13569-77. Epub 2002 Feb 4.

33.

Functional properties of the epithelial Ca2+ channel, ECaC.

Vennekens R, Droogmans G, Nilius B.

Gen Physiol Biophys. 2001 Sep;20(3):239-53. Review.

PMID:
11765215
34.

Function and expression of the epithelial Ca(2+) channel family: comparison of mammalian ECaC1 and 2.

Hoenderop JG, Vennekens R, Müller D, Prenen J, Droogmans G, Bindels RJ, Nilius B.

J Physiol. 2001 Dec 15;537(Pt 3):747-61.

35.

Differential activation of the volume-sensitive cation channel TRP12 (OTRPC4) and volume-regulated anion currents in HEK-293 cells.

Nilius B, Prenen J, Wissenbach U, Bödding M, Droogmans G.

Pflugers Arch. 2001 Nov;443(2):227-33.

PMID:
11713648
36.

CaT1 and the calcium release-activated calcium channel manifest distinct pore properties.

Voets T, Prenen J, Fleig A, Vennekens R, Watanabe H, Hoenderop JG, Bindels RJ, Droogmans G, Penner R, Nilius B.

J Biol Chem. 2001 Dec 21;276(51):47767-70. Epub 2001 Oct 30.

37.

Pharmacological modulation of monovalent cation currents through the epithelial Ca2+ channel ECaC1.

Nilius B, Prenen J, Vennekens R, Hoenderop JG, Bindels RJ, Droogmans G.

Br J Pharmacol. 2001 Oct;134(3):453-62.

38.

Ion channels and their functional role in vascular endothelium.

Nilius B, Droogmans G.

Physiol Rev. 2001 Oct;81(4):1415-59. Review.

39.

Aspartate residues of the Glu-Glu-Asp-Asp (EEDD) pore locus control selectivity and permeation of the T-type Ca(2+) channel alpha(1G).

Talavera K, Staes M, Janssens A, Klugbauer N, Droogmans G, Hofmann F, Nilius B.

J Biol Chem. 2001 Dec 7;276(49):45628-35. Epub 2001 Aug 28.

40.

The C-terminal part of the R-domain, but not the PDZ binding motif, of CFTR is involved in interaction with Ca(2+)-activated Cl- channels.

Wei L, Vankeerberghen A, Cuppens H, Cassiman JJ, Droogmans G, Nilius B.

Pflugers Arch. 2001 May;442(2):280-5.

PMID:
11417226
41.

Ca(2+)-activated Cl- channels in Ehrlich ascites tumor cells are distinct from mCLCA1, 2 and 3.

Papassotiriou J, Eggermont J, Droogmans G, Nilius B.

Pflugers Arch. 2001 May;442(2):273-9.

PMID:
11417225
42.

Modulation of the epithelial Ca2+ channel ECaC by extracellular pH.

Vennekens R, Prenen J, Hoenderop JG, Bindels RJ, Droogmans G, Nilius B.

Pflugers Arch. 2001 May;442(2):237-42.

PMID:
11417220
43.

Inhibition of VRAC by c-Src tyrosine kinase targeted to caveolae is mediated by the Src homology domains.

Trouet D, Carton I, Hermans D, Droogmans G, Nilius B, Eggermont J.

Am J Physiol Cell Physiol. 2001 Jul;281(1):C248-56.

44.

Inhibition of volume-regulated anion channels by dominant-negative caveolin-1.

Trouet D, Hermans D, Droogmans G, Nilius B, Eggermont J.

Biochem Biophys Res Commun. 2001 Jun 8;284(2):461-5.

PMID:
11394902
45.

Functional interaction between TRP4 and CFTR in mouse aorta endothelial cells.

Wei L, Freichel M, Jaspers M, Cuppens H, Cassiman JJ, Droogmans G, Flockerzi V, Nilius B.

BMC Physiol. 2001;1:3. Epub 2001 May 15.

46.

Modulation of the epithelial calcium channel, ECaC, by intracellular Ca2+.

Nilius B, Prenen J, Vennekens R, Hoenderop JG, Bindels RJ, Droogmans G.

Cell Calcium. 2001 Jun;29(6):417-28.

PMID:
11352507
47.

[Intracellular calcium: physiology and physiopathology].

Missiaen L, Callewaert G, Parys JB, Wuytack F, Raeymaekers L, Droogmans G, Nilius B, Eggermont J, De Smedt H.

Verh K Acad Geneeskd Belg. 2000;62(6):471-99. Review. Dutch.

PMID:
11196578
48.

Pore properties and ionic block of the rabbit epithelial calcium channel expressed in HEK 293 cells.

Vennekens R, Prenen J, Hoenderop JG, Bindels RJ, Droogmans G, Nilius B.

J Physiol. 2001 Jan 15;530(Pt 2):183-91.

49.

Lack of an endothelial store-operated Ca2+ current impairs agonist-dependent vasorelaxation in TRP4-/- mice.

Freichel M, Suh SH, Pfeifer A, Schweig U, Trost C, Weissgerber P, Biel M, Philipp S, Freise D, Droogmans G, Hofmann F, Flockerzi V, Nilius B.

Nat Cell Biol. 2001 Feb;3(2):121-7.

PMID:
11175743
50.

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