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Items: 1 to 50 of 108

1.

The Role of the Conserved SUMO-2/3 Cysteine Residue on Domain Structure Investigated Using Protein Chemical Synthesis.

Bouchenna J, Sénéchal M, Drobecq H, Stankovic-Valentin N, Vicogne J, Melnyk O.

Bioconjug Chem. 2019 Sep 18. doi: 10.1021/acs.bioconjchem.9b00598. [Epub ahead of print]

PMID:
31532181
2.

Pyrrolomycins Are Potent Natural Protonophores.

Valderrama K, Pradel E, Firsov AM, Drobecq H, Bauderlique-le Roy H, Villemagne B, Antonenko YN, Hartkoorn RC.

Antimicrob Agents Chemother. 2019 Sep 23;63(10). pii: e01450-19. doi: 10.1128/AAC.01450-19. Print 2019 Oct.

PMID:
31405863
3.

Native Chemical Ligation at Serine Revisited.

Snella B, Diemer V, Drobecq H, Agouridas V, Melnyk O.

Org Lett. 2018 Dec 7;20(23):7616-7619. doi: 10.1021/acs.orglett.8b03355. Epub 2018 Nov 13.

PMID:
30421931
4.

Catalysis of Thiol-Thioester Exchange by Water-Soluble Alkyldiselenols Applied to the Synthesis of Peptide Thioesters and SEA-Mediated Ligation.

Cargoët M, Diemer V, Snella B, Desmet R, Blanpain A, Drobecq H, Agouridas V, Melnyk O.

J Org Chem. 2018 Oct 19;83(20):12584-12594. doi: 10.1021/acs.joc.8b01903. Epub 2018 Oct 2.

PMID:
30230829
5.

Fast and facile preparation of nanostructured silicon surfaces for laser desorption/ionization mass spectrometry of small compounds.

Hamdi A, Enjalbal C, Drobecq H, Boukherroub R, Melnyk O, Ezzaouia H, Coffinier Y.

Rapid Commun Mass Spectrom. 2019 May;33 Suppl 1:66-74. doi: 10.1002/rcm.8245. Epub 2018 Sep 14.

6.

Tau/DDX6 interaction increases microRNA activity.

Chauderlier A, Gilles M, Spolcova A, Caillierez R, Chwastyniak M, Kress M, Drobecq H, Bonnefoy E, Pinet F, Weil D, Buée L, Galas MC, Lefebvre B.

Biochim Biophys Acta Gene Regul Mech. 2018 Aug;1861(8):762-772. doi: 10.1016/j.bbagrm.2018.06.006. Epub 2018 Jun 30.

PMID:
29966762
7.

Expression and Implication of Clusterin in Left Ventricular Remodeling After Myocardial Infarction.

Turkieh A, Fertin M, Bouvet M, Mulder P, Drobecq H, Lemesle G, Lamblin N, de Groote P, Porouchani S, Chwastyniak M, Beseme O, Amouyel P, Mouquet F, Balligand JL, Richard V, Bauters C, Pinet F.

Circ Heart Fail. 2018 Jun;11(6):e004838. doi: 10.1161/CIRCHEARTFAILURE.117.004838.

PMID:
29891738
8.

A simple and traceless solid phase method simplifies the assembly of large peptides and the access to challenging proteins.

Ollivier N, Desmet R, Drobecq H, Blanpain A, Boll E, Leclercq B, Mougel A, Vicogne J, Melnyk O.

Chem Sci. 2017 Aug 1;8(8):5362-5370. doi: 10.1039/c7sc01912b. Epub 2017 May 30. Erratum in: Chem Sci. 2017 Aug 1;8(8):5802.

9.

Hepatitis E Virus Lifecycle and Identification of 3 Forms of the ORF2 Capsid Protein.

Montpellier C, Wychowski C, Sayed IM, Meunier JC, Saliou JM, Ankavay M, Bull A, Pillez A, Abravanel F, Helle F, Brochot E, Drobecq H, Farhat R, Aliouat-Denis CM, Haddad JG, Izopet J, Meuleman P, Goffard A, Dubuisson J, Cocquerel L.

Gastroenterology. 2018 Jan;154(1):211-223.e8. doi: 10.1053/j.gastro.2017.09.020. Epub 2017 Sep 25.

PMID:
28958858
10.

Correction: A simple and traceless solid phase method simplifies the assembly of large peptides and the access to challenging proteins.

Ollivier N, Desmet R, Drobecq H, Blanpain A, Boll E, Leclercq B, Mougel A, Vicogne J, Melnyk O.

Chem Sci. 2017 Aug 1;8(8):5802. doi: 10.1039/c7sc90046e. Epub 2017 Jul 7.

11.

Carbon nanowalls: a new versatile graphene based interface for the laser desorption/ionization-mass spectrometry detection of small compounds in real samples.

Hosu IS, Sobaszek M, Ficek M, Bogdanowicz R, Drobecq H, Boussekey L, Barras A, Melnyk O, Boukherroub R, Coffinier Y.

Nanoscale. 2017 Jul 13;9(27):9701-9715. doi: 10.1039/c7nr01069a.

PMID:
28675223
12.

MoS2/TiO2/SiNW surface as an effective substrate for LDI-MS detection of glucose and glutathione in real samples.

Hamdi A, Hosu IS, Addad A, Hartkoorn R, Drobecq H, Melnyk O, Ezzaouia H, Boukherroub R, Coffinier Y.

Talanta. 2017 Aug 15;171:101-107. doi: 10.1016/j.talanta.2017.04.061. Epub 2017 Apr 27.

PMID:
28551115
13.

Characterization of peptide attachment on silicon nanowires by X-ray photoelectron spectroscopy and mass spectrometry.

Kurylo I, Dupré M, Cantel S, Enjalbal C, Drobecq H, Szunerits S, Melnyk O, Boukherroub R, Coffinier Y.

Analyst. 2017 Mar 13;142(6):969-978. doi: 10.1039/c6an02588a.

PMID:
28239690
14.

Kinetically Controlled Chemoselective Cyclization Simplifies the Access to Cyclic and Branched Peptides.

Boll E, Drobecq H, Lissy E, Cantrelle FX, Melnyk O.

Org Lett. 2016 Aug 5;18(15):3842-5. doi: 10.1021/acs.orglett.6b01847. Epub 2016 Jul 11.

PMID:
27398649
15.

Insight into the SEA amide thioester equilibrium. Application to the synthesis of thioesters at neutral pH.

Pira SL, El Mahdi O, Raibaut L, Drobecq H, Dheur J, Boll E, Melnyk O.

Org Biomol Chem. 2016 Jul 26;14(30):7211-6. doi: 10.1039/c6ob01079b.

PMID:
27282651
16.

A Central Cysteine Residue Is Essential for the Thermal Stability and Function of SUMO-1 Protein and SUMO-1 Peptide-Protein Conjugates.

Drobecq H, Boll E, Sénéchal M, Desmet R, Saliou JM, Lacapère JJ, Mougel A, Vicogne J, Melnyk O.

Bioconjug Chem. 2016 Jun 15;27(6):1540-6. doi: 10.1021/acs.bioconjchem.6b00211. Epub 2016 May 26.

PMID:
27195426
17.

Accelerating chemoselective peptide bond formation using bis(2-selenylethyl)amido peptide selenoester surrogates.

Raibaut L, Cargoët M, Ollivier N, Chang YM, Drobecq H, Boll E, Desmet R, Monbaliu JM, Melnyk O.

Chem Sci. 2016 Apr 21;7(4):2657-2665. doi: 10.1039/c5sc03459k. Epub 2016 Jan 11.

18.

Morphology and Molecular Composition of Purified Bovine Viral Diarrhea Virus Envelope.

Callens N, Brügger B, Bonnafous P, Drobecq H, Gerl MJ, Krey T, Roman-Sosa G, Rümenapf T, Lambert O, Dubuisson J, Rouillé Y.

PLoS Pathog. 2016 Mar 3;12(3):e1005476. doi: 10.1371/journal.ppat.1005476. eCollection 2016 Mar.

19.

Selectively Activatable Latent Thiol and Selenolesters Simplify the Access to Cyclic or Branched Peptide Scaffolds.

Raibaut L, Drobecq H, Melnyk O.

Org Lett. 2015 Jul 17;17(14):3636-9. doi: 10.1021/acs.orglett.5b01817. Epub 2015 Jul 2.

PMID:
26136111
20.

Synthesis of Unprotected Linear or Cyclic O-Acyl Isopeptides in Water Using Bis(2-sulfanylethyl)amido Peptide Ligation.

Desmet R, Pauzuolis M, Boll E, Drobecq H, Raibaut L, Melnyk O.

Org Lett. 2015 Jul 2;17(13):3354-7. doi: 10.1021/acs.orglett.5b01614. Epub 2015 Jun 15.

PMID:
26075704
21.

Necrosis- and apoptosis-related Met cleavages have divergent functional consequences.

Montagne R, Berbon M, Doublet L, Debreuck N, Baranzelli A, Drobecq H, Leroy C, Delhem N, Porte H, Copin MC, Dansin E, Furlan A, Tulasne D.

Cell Death Dis. 2015 May 21;6:e1769. doi: 10.1038/cddis.2015.132.

22.

Semi-synthesis of a HGF/SF kringle one (K1) domain scaffold generates a potent in vivo MET receptor agonist.

Simonneau C, Bérénice Leclercq, Mougel A, Adriaenssens E, Paquet C, Raibaut L, Ollivier N, Drobecq H, Marcoux J, Cianférani S, Tulasne D, de Jonge H, Melnyk O, Vicogne J.

Chem Sci. 2015 Mar 1;6(3):2110-2121. doi: 10.1039/c4sc03856h. Epub 2015 Jan 29.

23.

One-pot chemical synthesis of small ubiquitin-like modifier protein-peptide conjugates using bis(2-sulfanylethyl)amido peptide latent thioester surrogates.

Boll E, Drobecq H, Ollivier N, Blanpain A, Raibaut L, Desmet R, Vicogne J, Melnyk O.

Nat Protoc. 2015 Feb;10(2):269-92. doi: 10.1038/nprot.2015.013. Epub 2015 Jan 15.

PMID:
25591010
24.

Access to large cyclic peptides by a one-pot two-peptide segment ligation/cyclization process.

Boll E, Ebran JP, Drobecq H, El-Mahdi O, Raibaut L, Ollivier N, Melnyk O.

Org Lett. 2015 Jan 2;17(1):130-3. doi: 10.1021/ol503359w. Epub 2014 Dec 15.

PMID:
25506740
25.

Decoration of silicon nanostructures with copper particles for simultaneous selective capture and mass spectrometry detection of His-tagged model peptide.

Coffinier Y, Kurylo I, Drobecq H, Szunerits S, Melnyk O, Zaitsev VN, Boukherroub R.

Analyst. 2014 Oct 21;139(20):5155-63. doi: 10.1039/c4an01056f. Epub 2014 Aug 12.

PMID:
25112364
26.

Selenopeptide transamidation and metathesis.

Ollivier N, Blanpain A, Boll E, Raibaut L, Drobecq H, Melnyk O.

Org Lett. 2014 Aug 1;16(15):4032-5. doi: 10.1021/ol501866j. Epub 2014 Jul 14.

27.

Recovery of brain biomarkers following peroxisome proliferator-activated receptor agonist neuroprotective treatment before ischemic stroke.

Gelé P, Vingtdeux V, Potey C, Drobecq H, Ghestem A, Melnyk P, Buée L, Sergeant N, Bordet R.

Proteome Sci. 2014 May 6;12:24. doi: 10.1186/1477-5956-12-24. eCollection 2014.

28.

Anti-stress proteins produced by Bacteroides thetaiotaomicron after nutrient starvation.

Hochart-Behra AC, Drobecq H, Tourret M, Dubreuil L, Behra-Miellet J.

Anaerobe. 2014 Aug;28:18-23. doi: 10.1016/j.anaerobe.2014.04.008. Epub 2014 Apr 28.

PMID:
24785350
29.

Thiocarbamate-linked polysulfonate-peptide conjugates as selective hepatocyte growth factor receptor binders.

Besret S, Vicogne J, Dahmani F, Fafeur V, Desmet R, Drobecq H, Romieu A, Melnyk P, Melnyk O.

Bioconjug Chem. 2014 May 21;25(5):1000-10. doi: 10.1021/bc500137j. Epub 2014 May 5.

30.

Tidbits for the synthesis of bis(2-sulfanylethyl)amido (SEA) polystyrene resin, SEA peptides and peptide thioesters.

Ollivier N, Raibaut L, Blanpain A, Desmet R, Dheur J, Mhidia R, Boll E, Drobecq H, Pira SL, Melnyk O.

J Pept Sci. 2014 Feb;20(2):92-7. doi: 10.1002/psc.2580. Epub 2013 Nov 19.

PMID:
24254655
31.

Total synthesis of biotinylated N domain of human hepatocyte growth factor.

Raibaut L, Vicogne J, Leclercq B, Drobecq H, Desmet R, Melnyk O.

Bioorg Med Chem. 2013 Jun 15;21(12):3486-94. doi: 10.1016/j.bmc.2013.02.043. Epub 2013 Mar 14.

PMID:
23523386
32.

The level of Ets-1 protein is regulated by poly(ADP-ribose) polymerase-1 (PARP-1) in cancer cells to prevent DNA damage.

Legrand AJ, Choul-Li S, Spriet C, Idziorek T, Vicogne D, Drobecq H, Dantzer F, Villeret V, Aumercier M.

PLoS One. 2013;8(2):e55883. doi: 10.1371/journal.pone.0055883. Epub 2013 Feb 6.

33.

Identification of additional proteins in differential proteomics using protein interaction networks.

Gwinner F, Acosta-Martin AE, Boytard L, Chwastyniak M, Beseme O, Drobecq H, Duban-Deweer S, Juthier F, Jude B, Amouyel P, Pinet F, Schwikowski B.

Proteomics. 2013 Apr;13(7):1065-76. doi: 10.1002/pmic.201200482.

34.

Mycobacterial laminin-binding histone-like protein mediates collagen-dependent cytoadherence.

Dias AA, Raze D, de Lima CS, Marques MA, Drobecq H, Debrie AS, Ribeiro-Guimarães ML, Biet F, Pessolani MC.

Mem Inst Oswaldo Cruz. 2012 Dec;107 Suppl 1:174-82.

35.

Affinity surface-assisted laser desorption/ionization mass spectrometry for peptide enrichment.

Coffinier Y, Nguyen N, Drobecq H, Melnyk O, Thomy V, Boukherroub R.

Analyst. 2012 Dec 7;137(23):5527-32. doi: 10.1039/c2an35803d. Epub 2012 Oct 12.

PMID:
23061090
36.

Tau pathology modulates Pin1 post-translational modifications and may be relevant as biomarker.

Ando K, Dourlen P, Sambo AV, Bretteville A, Bélarbi K, Vingtdeux V, Eddarkaoui S, Drobecq H, Ghestem A, Bégard S, Demey-Thomas E, Melnyk P, Smet C, Lippens G, Maurage CA, Caillet-Boudin ML, Verdier Y, Vinh J, Landrieu I, Galas MC, Blum D, Hamdane M, Sergeant N, Buée L.

Neurobiol Aging. 2013 Mar;34(3):757-69. doi: 10.1016/j.neurobiolaging.2012.08.004. Epub 2012 Aug 25.

PMID:
22926167
37.

Surface-assisted laser desorption-ionization mass spectrometry on titanium dioxide (TiO2) nanotube layers.

Piret G, Kim D, Drobecq H, Coffinier Y, Melnyk O, Schmuki P, Boukherroub R.

Analyst. 2012 Jul 7;137(13):3058-63. doi: 10.1039/c2an35207a. Epub 2012 May 24.

PMID:
22624145
38.

Access to cyclic or branched peptides using bis(2-sulfanylethyl)amido side-chain derivatives of Asp and Glu.

Boll E, Dheur J, Drobecq H, Melnyk O.

Org Lett. 2012 May 4;14(9):2222-5. doi: 10.1021/ol300528r. Epub 2012 Apr 26.

PMID:
22537053
39.

A one-pot three-segment ligation strategy for protein chemical synthesis.

Ollivier N, Vicogne J, Vallin A, Drobecq H, Desmet R, El Mahdi O, Leclercq B, Goormachtigh G, Fafeur V, Melnyk O.

Angew Chem Int Ed Engl. 2012 Jan 2;51(1):209-13. doi: 10.1002/anie.201105837. Epub 2011 Nov 16. No abstract available.

PMID:
22095761
40.

Diamond nanowires for highly sensitive matrix-free mass spectrometry analysis of small molecules.

Coffinier Y, Szunerits S, Drobecq H, Melnyk O, Boukherroub R.

Nanoscale. 2012 Jan 7;4(1):231-8. doi: 10.1039/c1nr11274k. Epub 2011 Nov 14.

PMID:
22080363
41.

The coactivator activator CoAA regulates PEA3 group member transcriptional activity.

Verreman K, Baert JL, Verger A, Drobecq H, Ferreira E, de Launoit Y, Monte D.

Biochem J. 2011 Nov 1;439(3):469-77. doi: 10.1042/BJ20110728.

PMID:
21736557
42.

Membrane-associated DegP in Bordetella chaperones a repeat-rich secretory protein.

Baud C, Gutsche I, Willery E, de Paepe D, Drobecq H, Gilleron M, Locht C, Jamin M, Jacob-Dubuisson F.

Mol Microbiol. 2011 Jun;80(6):1625-36. doi: 10.1111/j.1365-2958.2011.07672.x. Epub 2011 May 12.

43.

High sensitive matrix-free mass spectrometry analysis of peptides using silicon nanowires-based digital microfluidic device.

Lapierre F, Piret G, Drobecq H, Melnyk O, Coffinier Y, Thomy V, Boukherroub R.

Lab Chip. 2011 May 7;11(9):1620-8. doi: 10.1039/c0lc00716a. Epub 2011 Mar 21.

PMID:
21423926
44.

Characterization of the Mycobacterium avium subsp. paratuberculosis laminin-binding/histone-like protein (Lbp/Hlp) which reacts with sera from patients with Crohn's disease.

Lefrançois LH, Pujol C, Bodier CC, Teixeira-Gomez AP, Drobecq H, Rosso ML, Raze D, Dias AA, Hugot JP, Chacon O, Barletta RG, Locht C, Vidal Pessolani MC, Biet F.

Microbes Infect. 2011 Jun;13(6):585-94. doi: 10.1016/j.micinf.2011.02.002. Epub 2011 Feb 18.

PMID:
21334452
45.

Chips from chips: application to the study of antibody responses to methylated proteins.

Piret G, Desmet R, Diesis E, Drobecq H, Segers J, Rouanet C, Debrie AS, Boukherroub R, Locht C, Melnyk O.

J Proteome Res. 2010 Dec 3;9(12):6467-78. doi: 10.1021/pr100707t. Epub 2010 Nov 5.

PMID:
20949974
46.

In situ chemical modification of peptide microarrays: application to the study of the antibody responses to methylated antigens.

Desmet R, Diesis E, Drobecq H, Rouanet C, Chemlal K, Debrie AS, Hougardy JM, Mascart F, Locht C, Melnyk O.

Methods Mol Biol. 2010;669:135-45. doi: 10.1007/978-1-60761-845-4_11.

PMID:
20857363
47.

In situ chemical modification of peptide microarrays: characterization by desorption/ionization on silicon nanowires.

Piret G, Drobecq H, Boukherroub R, Melnyk O.

Methods Mol Biol. 2010;669:125-33. doi: 10.1007/978-1-60761-845-4_10.

PMID:
20857362
48.

Combinatorial peptide ligand library plasma treatment: Advantages for accessing low-abundance proteins.

Beseme O, Fertin M, Drobecq H, Amouyel P, Pinet F.

Electrophoresis. 2010 Aug;31(16):2697-704. doi: 10.1002/elps.201000188.

PMID:
20665525
49.

Profile of macrophages in human abdominal aortic aneurysms: a transcriptomic, proteomic, and antibody protein array study.

Lamblin N, Ratajczak P, Hot D, Dubois E, Chwastyniak M, Beseme O, Drobecq H, Lemoine Y, Koussa M, Amouyel P, Pinet F.

J Proteome Res. 2010 Jul 2;9(7):3720-9. doi: 10.1021/pr100250s.

PMID:
20513153
50.

Decreased serine207 phosphorylation of troponin T as a biomarker for left ventricular remodelling after myocardial infarction.

Dubois E, Richard V, Mulder P, Lamblin N, Drobecq H, Henry JP, Amouyel P, Thuillez C, Bauters C, Pinet F.

Eur Heart J. 2011 Jan;32(1):115-23. doi: 10.1093/eurheartj/ehq108. Epub 2010 Apr 25.

PMID:
20418543

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