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Items: 16


SUMOylation Is an Inhibitory Constraint that Regulates the Prion-like Aggregation and Activity of CPEB3.

Drisaldi B, Colnaghi L, Fioriti L, Rao N, Myers C, Snyder AM, Metzger DJ, Tarasoff J, Konstantinov E, Fraser PE, Manley JL, Kandel ER.

Cell Rep. 2015 Jun 23;11(11):1694-702. doi: 10.1016/j.celrep.2015.04.061. Epub 2015 Jun 11.


The Persistence of Hippocampal-Based Memory Requires Protein Synthesis Mediated by the Prion-like Protein CPEB3.

Fioriti L, Myers C, Huang YY, Li X, Stephan JS, Trifilieff P, Colnaghi L, Kosmidis S, Drisaldi B, Pavlopoulos E, Kandel ER.

Neuron. 2015 Jun 17;86(6):1433-48. doi: 10.1016/j.neuron.2015.05.021. Epub 2015 Jun 11.


D1/D5 receptors and histone deacetylation mediate the Gateway Effect of LTP in hippocampal dentate gyrus.

Huang YY, Levine A, Kandel DB, Yin D, Colnaghi L, Drisaldi B, Kandel ER.

Learn Mem. 2014 Feb 18;21(3):153-60. doi: 10.1101/lm.032292.113.


Molecular mechanism for a gateway drug: epigenetic changes initiated by nicotine prime gene expression by cocaine.

Levine A, Huang Y, Drisaldi B, Griffin EA Jr, Pollak DD, Xu S, Yin D, Schaffran C, Kandel DB, Kandel ER.

Sci Transl Med. 2011 Nov 2;3(107):107ra109. doi: 10.1126/scitranslmed.3003062.


The CNS glycoprotein Shadoo has PrP(C)-like protective properties and displays reduced levels in prion infections.

Watts JC, Drisaldi B, Ng V, Yang J, Strome B, Horne P, Sy MS, Yoong L, Young R, Mastrangelo P, Bergeron C, Fraser PE, Carlson GA, Mount HT, Schmitt-Ulms G, Westaway D.

EMBO J. 2007 Sep 5;26(17):4038-50. Epub 2007 Aug 16.


Genetic mapping of activity determinants within cellular prion proteins: N-terminal modules in PrPC offset pro-apoptotic activity of the Doppel helix B/B' region.

Drisaldi B, Coomaraswamy J, Mastrangelo P, Strome B, Yang J, Watts JC, Chishti MA, Marvi M, Windl O, Ahrens R, Major F, Sy MS, Kretzschmar H, Fraser PE, Mount HT, Westaway D.

J Biol Chem. 2004 Dec 31;279(53):55443-54. Epub 2004 Sep 29.


In vivo reduction of amyloid-beta by a mutant copper transporter.

Phinney AL, Drisaldi B, Schmidt SD, Lugowski S, Coronado V, Liang Y, Horne P, Yang J, Sekoulidis J, Coomaraswamy J, Chishti MA, Cox DW, Mathews PM, Nixon RA, Carlson GA, St George-Hyslop P, Westaway D.

Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14193-8. Epub 2003 Nov 14.


Molecular distinction between pathogenic and infectious properties of the prion protein.

Chiesa R, Piccardo P, Quaglio E, Drisaldi B, Si-Hoe SL, Takao M, Ghetti B, Harris DA.

J Virol. 2003 Jul;77(13):7611-22.


A murine model of a familial prion disease.

Harris DA, Chiesa R, Drisaldi B, Quaglio E, Migheli A, Piccardo P, Ghetti B.

Clin Lab Med. 2003 Mar;23(1):175-86. Review.


Mutant PrP is delayed in its exit from the endoplasmic reticulum, but neither wild-type nor mutant PrP undergoes retrotranslocation prior to proteasomal degradation.

Drisaldi B, Stewart RS, Adles C, Stewart LR, Quaglio E, Biasini E, Fioriti L, Chiesa R, Harris DA.

J Biol Chem. 2003 Jun 13;278(24):21732-43. Epub 2003 Mar 26.


A transgenic model of a familial prion disease.

Harris DA, Chiesa R, Drisaldi B, Quaglio E, Migheli A, Piccardo P, Ghetti B.

Arch Virol Suppl. 2000;(16):103-12. Review.


Accumulation of protease-resistant prion protein (PrP) and apoptosis of cerebellar granule cells in transgenic mice expressing a PrP insertional mutation.

Chiesa R, Drisaldi B, Quaglio E, Migheli A, Piccardo P, Ghetti B, Harris DA.

Proc Natl Acad Sci U S A. 2000 May 9;97(10):5574-9.


Brain copper content and cuproenzyme activity do not vary with prion protein expression level.

Waggoner DJ, Drisaldi B, Bartnikas TB, Casareno RL, Prohaska JR, Gitlin JD, Harris DA.

J Biol Chem. 2000 Mar 17;275(11):7455-8.


Comparative mapping of the prion gene (PRNP) locus in cattle, sheep and human with PCR-generated probes.

Castiglioni B, Comincini S, Drisaldi B, Motta T, Ferretti L.

Mamm Genome. 1998 Oct;9(10):853-5. No abstract available. Erratum in: Mamm Genome 1999 May;10(5):533.


Isolation of coding sequences from bovine cosmids by means of exon trapping.

Comincini S, Drisaldi B, Ferretti L.

Mamm Genome. 1997 Jul;8(7):486-90.


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