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Transglutaminase 2 limits the extravasation and the resultant myocardial fibrosis associated with factor XIII-A deficiency.

Griffin KJ, Newell LM, Simpson KR, Beckers CML, Drinkhill MJ, Standeven KF, Cheah LT, Iismaa SE, Grant PJ, Jackson CL, Pease RJ.

Atherosclerosis. 2019 Dec 17;294:1-9. doi: 10.1016/j.atherosclerosis.2019.12.013. [Epub ahead of print]


Mechanically activated Piezo1 channels of cardiac fibroblasts stimulate p38 mitogen-activated protein kinase activity and interleukin-6 secretion.

Blythe NM, Muraki K, Ludlow MJ, Stylianidis V, Gilbert HTJ, Evans EL, Cuthbertson K, Foster R, Swift J, Li J, Drinkhill MJ, van Nieuwenhoven FA, Porter KE, Beech DJ, Turner NA.

J Biol Chem. 2019 Nov 15;294(46):17395-17408. doi: 10.1074/jbc.RA119.009167. Epub 2019 Oct 4.


Fibroblast-specific deletion of interleukin-1 receptor-1 reduces adverse cardiac remodeling following myocardial infarction.

Bageghni SA, Hemmings KE, Yuldasheva NY, Maqbool A, Gamboa-Esteves FO, Humphreys NE, Jackson MS, Denton CP, Francis S, Porter KE, Ainscough JF, Pinteaux E, Drinkhill MJ, Turner NA.

JCI Insight. 2019 Aug 8;5. pii: 125074. doi: 10.1172/jci.insight.125074.


Differential control of muscle sympathetic outflow in single units of humans: a role for pulmonary artery baroreceptors?

Moore JP, Drinkhill MJ.

Am J Physiol Heart Circ Physiol. 2019 Feb 1;316(2):H430-H431. doi: 10.1152/ajpheart.00817.2018. No abstract available.


Beta1-adrenoceptor antagonist, metoprolol attenuates cardiac myocyte Ca2+ handling dysfunction in rats with pulmonary artery hypertension.

Fowler ED, Drinkhill MJ, Norman R, Pervolaraki E, Stones R, Steer E, Benoist D, Steele DS, Calaghan SC, White E.

J Mol Cell Cardiol. 2018 Jul;120:74-83. doi: 10.1016/j.yjmcc.2018.05.015. Epub 2018 May 26.


Cardiac fibroblast-specific p38α MAP kinase promotes cardiac hypertrophy via a putative paracrine interleukin-6 signaling mechanism.

Bageghni SA, Hemmings KE, Zava N, Denton CP, Porter KE, Ainscough JFX, Drinkhill MJ, Turner NA.

FASEB J. 2018 Sep;32(9):4941-4954. doi: 10.1096/fj.201701455RR. Epub 2018 Mar 30.


Diastolic dysfunction in pulmonary artery hypertension: Creatine kinase and the potential therapeutic benefit of beta-blockers.

Fowler ED, Drinkhill MJ, Stones R, White E.

Clin Exp Pharmacol Physiol. 2018 Apr;45(4):384-389. doi: 10.1111/1440-1681.12898. Epub 2018 Jan 10. Review.


Piezo1 channels sense whole body physical activity to reset cardiovascular homeostasis and enhance performance.

Rode B, Shi J, Endesh N, Drinkhill MJ, Webster PJ, Lotteau SJ, Bailey MA, Yuldasheva NY, Ludlow MJ, Cubbon RM, Li J, Futers TS, Morley L, Gaunt HJ, Marszalek K, Viswambharan H, Cuthbertson K, Baxter PD, Foster R, Sukumar P, Weightman A, Calaghan SC, Wheatcroft SB, Kearney MT, Beech DJ.

Nat Commun. 2017 Aug 24;8(1):350. doi: 10.1038/s41467-017-00429-3.


Cardiomyocyte--specific expression of the nuclear matrix protein, CIZ1, stimulates production of mono-nucleated cells with an extended window of proliferation in the postnatal mouse heart.

Bageghni SA, Frentzou GA, Drinkhill MJ, Mansfield W, Coverley D, Ainscough JF.

Biol Open. 2017 Jan 15;6(1):92-99. doi: 10.1242/bio.021550.


Tenascin C upregulates interleukin-6 expression in human cardiac myofibroblasts via toll-like receptor 4.

Maqbool A, Spary EJ, Manfield IW, Ruhmann M, Zuliani-Alvarez L, Gamboa-Esteves FO, Porter KE, Drinkhill MJ, Midwood KS, Turner NA.

World J Cardiol. 2016 May 26;8(5):340-50. doi: 10.4330/wjc.v8.i5.340.


Decreased creatine kinase is linked to diastolic dysfunction in rats with right heart failure induced by pulmonary artery hypertension.

Fowler ED, Benoist D, Drinkhill MJ, Stones R, Helmes M, Wüst RC, Stienen GJ, Steele DS, White E.

J Mol Cell Cardiol. 2015 Sep;86:1-8. doi: 10.1016/j.yjmcc.2015.06.016. Epub 2015 Jun 24.


A state of reversible compensated ventricular dysfunction precedes pathological remodelling in response to cardiomyocyte-specific activity of angiotensin II type-1 receptor in mice.

Frentzou GA, Drinkhill MJ, Turner NA, Ball SG, Ainscough JF.

Dis Model Mech. 2015 Aug 1;8(8):783-94. doi: 10.1242/dmm.019174. Epub 2015 Jun 18.


Systems approach to the study of stretch and arrhythmias in right ventricular failure induced in rats by monocrotaline.

Benoist D, Stones R, Benson AP, Fowler ED, Drinkhill MJ, Hardy ME, Saint DA, Cazorla O, Bernus O, White E.

Prog Biophys Mol Biol. 2014 Aug;115(2-3):162-72. doi: 10.1016/j.pbiomolbio.2014.06.008. Epub 2014 Jul 9.


Alternating hemiplegia of childhood-related neural and behavioural phenotypes in Na+,K+-ATPase α3 missense mutant mice.

Kirshenbaum GS, Dawson N, Mullins JG, Johnston TH, Drinkhill MJ, Edwards IJ, Fox SH, Pratt JA, Brotchie JM, Roder JC, Clapcote SJ.

PLoS One. 2013;8(3):e60141. doi: 10.1371/journal.pone.0060141. Epub 2013 Mar 20.


Cardiac arrhythmia mechanisms in rats with heart failure induced by pulmonary hypertension.

Benoist D, Stones R, Drinkhill MJ, Benson AP, Yang Z, Cassan C, Gilbert SH, Saint DA, Cazorla O, Steele DS, Bernus O, White E.

Am J Physiol Heart Circ Physiol. 2012 Jun 1;302(11):H2381-95. doi: 10.1152/ajpheart.01084.2011. Epub 2012 Mar 16.


Reflexes from pulmonary arterial baroreceptors in dogs: interaction with carotid sinus baroreceptors.

Moore JP, Hainsworth R, Drinkhill MJ.

J Physiol. 2011 Aug 15;589(Pt 16):4041-52. doi: 10.1113/jphysiol.2011.210732. Epub 2011 Jun 20.


Resting sympathetic nerve activity is related to age, sex and arterial pressure but not to α2-adrenergic receptor subtype.

Maqbool A, West RM, Galloway SL, Drinkhill MJ, Mary DA, Greenwood JP, Ball SG.

J Hypertens. 2010 Oct;28(10):2084-93. doi: 10.1097/HJH.0b013e32833c8a36.


Angiotensin II type-1 receptor activation in the adult heart causes blood pressure-independent hypertrophy and cardiac dysfunction.

Ainscough JF, Drinkhill MJ, Sedo A, Turner NA, Brooke DA, Balmforth AJ, Ball SG.

Cardiovasc Res. 2009 Feb 15;81(3):592-600. doi: 10.1093/cvr/cvn230. Epub 2008 Aug 14.


Vasodilator effects of leptin on canine isolated mesenteric arteries and veins.

Mohammed MM, Myers DS, Sofola OA, Hainsworth R, Drinkhill MJ.

Clin Exp Pharmacol Physiol. 2007 Aug;34(8):771-4.


Cardiovascular adjustments for life at high altitude.

Hainsworth R, Drinkhill MJ.

Respir Physiol Neurobiol. 2007 Sep 30;158(2-3):204-11. Epub 2007 May 18. Review.


Commentary on Viewpoint "Human experimentation: no accurate, quantitative data?".

Hainsworth R, Drinkhill MJ.

J Appl Physiol (1985). 2007 Mar;102(3):1293. No abstract available.


The autonomic nervous system at high altitude.

Hainsworth R, Drinkhill MJ, Rivera-Chira M.

Clin Auton Res. 2007 Feb;17(1):13-9. Epub 2007 Jan 30. Review.


Counterpoint: active venoconstriction is not important in maintaining or raising end-diastolic volume and stroke volume during exercise and orthostasis.

Hainsworth R, Drinkhill MJ.

J Appl Physiol (1985). 2006 Oct;101(4):1264-5; discussion 1265-6, 1270. No abstract available.


Central nucleus of amygdala projections to rostral ventrolateral medulla neurones activated by decreased blood pressure.

Saha S, Drinkhill MJ, Moore JP, Batten TF.

Eur J Neurosci. 2005 Apr;21(7):1921-30.


Effects of dietary salt loading on the responses of isolated rat mesenteric arteries to leptin.

Jaffar MM, Myers DS, Hainsworth LJ, Hainsworth R, Drinkhill MJ.

Am J Hypertens. 2005 Apr;18(4 Pt 1):500-3.


High-salt diet and responses of the pressurized mesenteric artery of the dog to noradrenaline and acetylcholine.

Sofola O, Knill A, Myers D, Hainsworth R, Drinkhill M.

Clin Exp Pharmacol Physiol. 2004 Oct;31(10):696-9.


Pulmonary arterial distension and vagal afferent nerve activity in anaesthetized dogs.

Moore JP, Hainsworth R, Drinkhill MJ.

J Physiol. 2004 Mar 16;555(Pt 3):805-14. Epub 2004 Jan 23.


Influence of dietary salt intake on the response of isolated perfused mesenteric veins of the dog to vasoactive agents.

Hainsworth R, Sofola OA, Knill AJ, Drinkhill MJ.

Am J Hypertens. 2003 Jan;16(1):6-10.


Absence of reflex vascular responses from the intrapulmonary circulation in anaesthetised dogs.

McMahon NC, Drinkhill MJ, Myers DS, Hainsworth R.

Exp Physiol. 2000 Jul;85(4):421-30.


Reflex responses from the main pulmonary artery and bifurcation in anaesthetised dogs.

McMahon NC, Drinkhill MJ, Myers DS, Hainsworth R.

Exp Physiol. 2000 Jul;85(4):411-20.


Absence of early resetting of coronary baroreceptors in anaesthetized dogs.

McMahon NC, Drinkhill MJ, Hainsworth R.

J Physiol. 1998 Dec 1;513 ( Pt 2):543-9.


Reflex control of splanchnic blood volume in anaesthetized dogs.

Noble BJ, Drinkhill MJ, Myers DS, Hainsworth R.

J Physiol. 1998 Nov 15;513 ( Pt 1):263-72.


Reflex vascular responses in the anesthetized dog to large rapid changes in carotid sinus pressure.

Doe CP, Self DA, Drinkhill MJ, McMahon N, Myers DS, Hainsworth R.

Am J Physiol. 1998 Oct;275(4):H1169-77. doi: 10.1152/ajpheart.1998.275.4.H1169.


Blood mobilization from the liver of the anaesthetized dog.

Noble BJ, Drinkhill MJ, Myers DS, Hainsworth R.

Exp Physiol. 1998 Jul;83(4):513-22.


Structure and in vitro function of human subcutaneous small arteries in mild heart failure.

Stephens N, Drinkhill MJ, Hall AS, Ball SG, Heagerty AM.

Am J Physiol. 1998 May;274(5):C1298-305. doi: 10.1152/ajpcell.1998.274.5.C1298.


Reflex vascular responses to alterations in abdominal arterial pressure and flow in anaesthetized dogs.

Drinkhill MJ, Doe CP, Myers DS, Self DA, Hainsworth R.

Exp Physiol. 1997 Nov;82(6):995-1005.


Delayed sympathetic efferent responses to coronary baroreceptor unloading in anaesthetized dogs.

Drinkhill MJ, McMahon NC, Hainsworth R.

J Physiol. 1996 Nov 15;497 ( Pt 1):261-9.


Reflex vascular responses to abdominal venous distension in the anesthetized dog.

Doe CP, Drinkhill MJ, Myers DS, Self DA, Hainsworth R.

Am J Physiol. 1996 Sep;271(3 Pt 2):H1049-56.


Afferent discharges from coronary arterial and ventricular receptors in anaesthetized dogs.

Drinkhill MJ, Moore J, Hainsworth R.

J Physiol. 1993 Dec;472:785-99.


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