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Items: 21


Targeted molecular-genetic imaging and ligand-directed therapy in aggressive variant prostate cancer.

Ferrara F, Staquicini DI, Driessen WHP, D'Angelo S, Dobroff AS, Barry M, Lomo LC, Staquicini FI, Cardó-Vila M, Soghomonyan S, Alauddin MM, Flores LG 2nd, Arap MA, Lauer RC, Mathew P, Efstathiou E, Aparicio AM, Troncoso P, Navone NM, Logothetis CJ, Marchiò S, Gelovani JG, Sidman RL, Pasqualini R, Arap W.

Proc Natl Acad Sci U S A. 2016 Nov 8;113(45):12786-12791. doi: 10.1073/pnas.1615400113. Epub 2016 Oct 24.


Towards a transcriptome-based theranostic platform for unfavorable breast cancer phenotypes.

Dobroff AS, D'Angelo S, Eckhardt BL, Ferrara F, Staquicini DI, Cardó-Vila M, Staquicini FI, Nunes DN, Kim K, Driessen WHP, Hajitou A, Lomo LC, Barry M, Krishnamurthy S, Sahin A, Woodward WA, Prossnitz ER, Anderson RL, Dias-Neto E, Brown-Glaberman UA, Royce ME, Ueno NT, Cristofanilli M, Hortobagyi GN, Marchiò S, Gelovani JG, Sidman RL, Arap W, Pasqualini R.

Proc Natl Acad Sci U S A. 2016 Nov 8;113(45):12780-12785. doi: 10.1073/pnas.1615288113. Epub 2016 Oct 24.


Integrated nanotechnology platform for tumor-targeted multimodal imaging and therapeutic cargo release.

Hosoya H, Dobroff AS, Driessen WH, Cristini V, Brinker LM, Staquicini FI, Cardó-Vila M, D'Angelo S, Ferrara F, Proneth B, Lin YS, Dunphy DR, Dogra P, Melancon MP, Stafford RJ, Miyazono K, Gelovani JG, Kataoka K, Brinker CJ, Sidman RL, Arap W, Pasqualini R.

Proc Natl Acad Sci U S A. 2016 Feb 16;113(7):1877-82. doi: 10.1073/pnas.1525796113. Epub 2016 Feb 2.


Targeting the interleukin-11 receptor α in metastatic prostate cancer: A first-in-man study.

Pasqualini R, Millikan RE, Christianson DR, Cardó-Vila M, Driessen WH, Giordano RJ, Hajitou A, Hoang AG, Wen S, Barnhart KF, Baze WB, Marcott VD, Hawke DH, Do KA, Navone NM, Efstathiou E, Troncoso P, Lobb RR, Logothetis CJ, Arap W.

Cancer. 2015 Jul 15;121(14):2411-21. doi: 10.1002/cncr.29344. Epub 2015 Apr 1.


Targeting IL11 Receptor in Leukemia and Lymphoma: A Functional Ligand-Directed Study and Hematopathology Analysis of Patient-Derived Specimens.

Karjalainen K, Jaalouk DE, Bueso-Ramos C, Bover L, Sun Y, Kuniyasu A, Driessen WH, Cardó-Vila M, Rietz C, Zurita AJ, O'Brien S, Kantarjian HM, Cortes JE, Calin GA, Koivunen E, Arap W, Pasqualini R.

Clin Cancer Res. 2015 Jul 1;21(13):3041-51. doi: 10.1158/1078-0432.CCR-13-3059. Epub 2015 Mar 16.


Selection and identification of ligand peptides targeting a model of castrate-resistant osteogenic prostate cancer and their receptors.

Mandelin J, Cardó-Vila M, Driessen WH, Mathew P, Navone NM, Lin SH, Logothetis CJ, Rietz AC, Dobroff AS, Proneth B, Sidman RL, Pasqualini R, Arap W.

Proc Natl Acad Sci U S A. 2015 Mar 24;112(12):3776-81. doi: 10.1073/pnas.1500128112. Epub 2015 Mar 11.


Semi-quantitative Multispectral Optoacoustic Tomography (MSOT) for volumetric PK imaging of gastric emptying.

Morscher S, Driessen WH, Claussen J, Burton NC.

Photoacoustics. 2014 Jun 27;2(3):103-10. doi: 10.1016/j.pacs.2014.06.001. eCollection 2014 Sep.


A macrophage uptaking near-infrared chemical probe CDnir7 for in vivo imaging of inflammation.

Kang NY, Park SJ, Ang XW, Samanta A, Driessen WH, Ntziachristos V, Vasquez KO, Peterson JD, Yun SW, Chang YT.

Chem Commun (Camb). 2014 Jun 25;50(50):6589-91. doi: 10.1039/c4cc02038c.


Bacteriophage Associated Silicon Particles: Design and Characterization of a Novel Theranostic Vector with Improved Payload Carrying Potential.

Srinivasan S, Alexander JF, Driessen WH, Leonard F, Ye H, Liu X, Arap W, Pasqualini R, Ferrari M, Godin B.

J Mater Chem B. 2013 Oct 21;1(39). doi: 10.1039/C3TB20595A.


Mechanism of action and initial evaluation of a membrane active all-D-enantiomer antimicrobial peptidomimetic.

McGrath DM, Barbu EM, Driessen WH, Lasco TM, Tarrand JJ, Okhuysen PC, Kontoyiannis DP, Sidman RL, Pasqualini R, Arap W.

Proc Natl Acad Sci U S A. 2013 Feb 26;110(9):3477-82. doi: 10.1073/pnas.1221924110. Epub 2013 Jan 23.


Multispectral opto-acoustic tomography (MSOT) of the brain and glioblastoma characterization.

Burton NC, Patel M, Morscher S, Driessen WH, Claussen J, Beziere N, Jetzfellner T, Taruttis A, Razansky D, Bednar B, Ntziachristos V.

Neuroimage. 2013 Jan 15;65:522-8. doi: 10.1016/j.neuroimage.2012.09.053. Epub 2012 Sep 28.


A peptidomimetic targeting white fat causes weight loss and improved insulin resistance in obese monkeys.

Barnhart KF, Christianson DR, Hanley PW, Driessen WH, Bernacky BJ, Baze WB, Wen S, Tian M, Ma J, Kolonin MG, Saha PK, Do KA, Hulvat JF, Gelovani JG, Chan L, Arap W, Pasqualini R.

Sci Transl Med. 2011 Nov 9;3(108):108ra112. doi: 10.1126/scitranslmed.3002621.


Enhanced relative biological effectiveness of proton radiotherapy in tumor cells with internalized gold nanoparticles.

Polf JC, Bronk LF, Driessen WH, Arap W, Pasqualini R, Gillin M.

Appl Phys Lett. 2011 May 9;98(19):193702. Epub 2011 May 10.


In vivo anti-tumor effect of expressing p14ARF-TAT using a FGF2-targeted cationic lipid vector.

Niu G, Driessen WH, Sullivan SM, Hughes JA.

Pharm Res. 2011 Apr;28(4):720-30. doi: 10.1007/s11095-010-0353-x. Epub 2011 Jan 19.


Systemic combinatorial peptide selection yields a non-canonical iron-mimicry mechanism for targeting tumors in a mouse model of human glioblastoma.

Staquicini FI, Ozawa MG, Moya CA, Driessen WH, Barbu EM, Nishimori H, Soghomonyan S, Flores LG 2nd, Liang X, Paolillo V, Alauddin MM, Basilion JP, Furnari FB, Bogler O, Lang FF, Aldape KD, Fuller GN, Höök M, Gelovani JG, Sidman RL, Cavenee WK, Pasqualini R, Arap W.

J Clin Invest. 2011 Jan;121(1):161-73. doi: 10.1172/JCI44798. Epub 2010 Dec 22.


On the synergistic effects of ligand-mediated and phage-intrinsic properties during in vivo selection.

Driessen WH, Bronk LF, Edwards JK, Proneth B, Souza GR, Decuzzi P, Pasqualini R, Arap W.

Adv Genet. 2010;69:115-33. doi: 10.1016/S0065-2660(10)69005-0.


An integrated approach for the rational design of nanovectors for biomedical imaging and therapy.

Godin B, Driessen WH, Proneth B, Lee SY, Srinivasan S, Rumbaut R, Arap W, Pasqualini R, Ferrari M, Decuzzi P.

Adv Genet. 2010;69:31-64. doi: 10.1016/S0065-2660(10)69009-8. Review.


Ligand-directed cancer gene therapy to angiogenic vasculature.

Driessen WHP, Ozawa MG, Arap W, Pasqualini R.

Adv Genet. 2009;67:103-121. doi: 10.1016/S0065-2660(09)67004-8. Review.


Development of peptide-targeted lipoplexes to CXCR4-expressing rat glioma cells and rat proliferating endothelial cells.

Driessen WH, Fujii N, Tamamura H, Sullivan SM.

Mol Ther. 2008 Mar;16(3):516-24. doi: 10.1038/ Epub 2008 Jan 15.


Peptide-mediated gene transfer of cationic lipid/plasmid DNA complexes to endothelial cells.

Anwer K, Kao G, Rolland A, Driessen WH, Sullivan SM.

J Drug Target. 2004 May;12(4):215-21.


DC-SIGN-specific liposomal targeting and selective intracellular compound delivery to human myeloid dendritic cells: implications for HIV disease.

Gieseler RK, Marquitan G, Hahn MJ, Perdon LA, Driessen WH, Sullivan SM, Scolaro MJ.

Scand J Immunol. 2004 May;59(5):415-24.

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