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Items: 1 to 50 of 76

1.

Tumor-targeted 4-1BB agonists for combination with T cell bispecific antibodies as off-the-shelf therapy.

Claus C, Ferrara C, Xu W, Sam J, Lang S, Uhlenbrock F, Albrecht R, Herter S, Schlenker R, Hüsser T, Diggelmann S, Challier J, Mössner E, Hosse RJ, Hofer T, Brünker P, Joseph C, Benz J, Ringler P, Stahlberg H, Lauer M, Perro M, Chen S, Küttel C, Bhavani Mohan PL, Nicolini V, Birk MC, Ongaro A, Prince C, Gianotti R, Dugan G, Whitlow CT, Solingapuram Sai KK, Caudell DL, Burgos-Rodriguez AG, Cline JM, Hettich M, Ceppi M, Giusti AM, Crameri F, Driessen W, Morcos PN, Freimoser-Grundschober A, Levitsky V, Amann M, Grau-Richards S, von Hirschheydt T, Tournaviti S, Mølhøj M, Fauti T, Heinzelmann-Schwarz V, Teichgräber V, Colombetti S, Bacac M, Zippelius A, Klein C, Umaña P.

Sci Transl Med. 2019 Jun 12;11(496). pii: eaav5989. doi: 10.1126/scitranslmed.aav5989.

PMID:
31189721
2.

Liver-Targeted Anti-HBV Single-Stranded Oligonucleotides with Locked Nucleic Acid Potently Reduce HBV Gene Expression In Vivo.

Javanbakht H, Mueller H, Walther J, Zhou X, Lopez A, Pattupara T, Blaising J, Pedersen L, Albæk N, Jackerott M, Shi T, Ploix C, Driessen W, Persson R, Ravn J, Young JAT, Ottosen S.

Mol Ther Nucleic Acids. 2018 Jun 1;11:441-454. doi: 10.1016/j.omtn.2018.02.005. Epub 2018 Feb 23.

3.

Targeted molecular-genetic imaging and ligand-directed therapy in aggressive variant prostate cancer.

Ferrara F, Staquicini DI, Driessen WHP, D'Angelo S, Dobroff AS, Barry M, Lomo LC, Staquicini FI, Cardó-Vila M, Soghomonyan S, Alauddin MM, Flores LG 2nd, Arap MA, Lauer RC, Mathew P, Efstathiou E, Aparicio AM, Troncoso P, Navone NM, Logothetis CJ, Marchiò S, Gelovani JG, Sidman RL, Pasqualini R, Arap W.

Proc Natl Acad Sci U S A. 2016 Nov 8;113(45):12786-12791. doi: 10.1073/pnas.1615400113. Epub 2016 Oct 24.

4.

Towards a transcriptome-based theranostic platform for unfavorable breast cancer phenotypes.

Dobroff AS, D'Angelo S, Eckhardt BL, Ferrara F, Staquicini DI, Cardó-Vila M, Staquicini FI, Nunes DN, Kim K, Driessen WHP, Hajitou A, Lomo LC, Barry M, Krishnamurthy S, Sahin A, Woodward WA, Prossnitz ER, Anderson RL, Dias-Neto E, Brown-Glaberman UA, Royce ME, Ueno NT, Cristofanilli M, Hortobagyi GN, Marchiò S, Gelovani JG, Sidman RL, Arap W, Pasqualini R.

Proc Natl Acad Sci U S A. 2016 Nov 8;113(45):12780-12785. doi: 10.1073/pnas.1615288113. Epub 2016 Oct 24.

5.

Integrated nanotechnology platform for tumor-targeted multimodal imaging and therapeutic cargo release.

Hosoya H, Dobroff AS, Driessen WH, Cristini V, Brinker LM, Staquicini FI, Cardó-Vila M, D'Angelo S, Ferrara F, Proneth B, Lin YS, Dunphy DR, Dogra P, Melancon MP, Stafford RJ, Miyazono K, Gelovani JG, Kataoka K, Brinker CJ, Sidman RL, Arap W, Pasqualini R.

Proc Natl Acad Sci U S A. 2016 Feb 16;113(7):1877-82. doi: 10.1073/pnas.1525796113. Epub 2016 Feb 2.

6.

Optical mesoscopy without the scatter: broadband multispectral optoacoustic mesoscopy.

Chekkoury A, Gateau J, Driessen W, Symvoulidis P, Bézière N, Feuchtinger A, Walch A, Ntziachristos V.

Biomed Opt Express. 2015 Jul 31;6(9):3134-48. doi: 10.1364/BOE.6.003134. eCollection 2015 Sep 1.

7.

Targeting the interleukin-11 receptor α in metastatic prostate cancer: A first-in-man study.

Pasqualini R, Millikan RE, Christianson DR, Cardó-Vila M, Driessen WH, Giordano RJ, Hajitou A, Hoang AG, Wen S, Barnhart KF, Baze WB, Marcott VD, Hawke DH, Do KA, Navone NM, Efstathiou E, Troncoso P, Lobb RR, Logothetis CJ, Arap W.

Cancer. 2015 Jul 15;121(14):2411-21. doi: 10.1002/cncr.29344. Epub 2015 Apr 1.

8.

Phthalocyanine photosensitizers as contrast agents for in vivo photoacoustic tumor imaging.

Attia AB, Balasundaram G, Driessen W, Ntziachristos V, Olivo M.

Biomed Opt Express. 2015 Jan 26;6(2):591-8. doi: 10.1364/BOE.6.000591. eCollection 2015 Feb 1.

9.

Targeting IL11 Receptor in Leukemia and Lymphoma: A Functional Ligand-Directed Study and Hematopathology Analysis of Patient-Derived Specimens.

Karjalainen K, Jaalouk DE, Bueso-Ramos C, Bover L, Sun Y, Kuniyasu A, Driessen WH, Cardó-Vila M, Rietz C, Zurita AJ, O'Brien S, Kantarjian HM, Cortes JE, Calin GA, Koivunen E, Arap W, Pasqualini R.

Clin Cancer Res. 2015 Jul 1;21(13):3041-51. doi: 10.1158/1078-0432.CCR-13-3059. Epub 2015 Mar 16.

10.

Selection and identification of ligand peptides targeting a model of castrate-resistant osteogenic prostate cancer and their receptors.

Mandelin J, Cardó-Vila M, Driessen WH, Mathew P, Navone NM, Lin SH, Logothetis CJ, Rietz AC, Dobroff AS, Proneth B, Sidman RL, Pasqualini R, Arap W.

Proc Natl Acad Sci U S A. 2015 Mar 24;112(12):3776-81. doi: 10.1073/pnas.1500128112. Epub 2015 Mar 11.

11.

Molecular photoacoustic imaging of breast cancer using an actively targeted conjugated polymer.

Balasundaram G, Ho CJ, Li K, Driessen W, Dinish US, Wong CL, Ntziachristos V, Liu B, Olivo M.

Int J Nanomedicine. 2015 Jan 8;10:387-97. doi: 10.2147/IJN.S73558. eCollection 2015.

12.

Semi-quantitative Multispectral Optoacoustic Tomography (MSOT) for volumetric PK imaging of gastric emptying.

Morscher S, Driessen WH, Claussen J, Burton NC.

Photoacoustics. 2014 Jun 27;2(3):103-10. doi: 10.1016/j.pacs.2014.06.001. eCollection 2014 Sep.

13.

Multifunctional photosensitizer-based contrast agents for photoacoustic imaging.

Ho CJ, Balasundaram G, Driessen W, McLaren R, Wong CL, Dinish US, Attia AB, Ntziachristos V, Olivo M.

Sci Rep. 2014 Jun 18;4:5342. doi: 10.1038/srep05342.

14.

A macrophage uptaking near-infrared chemical probe CDnir7 for in vivo imaging of inflammation.

Kang NY, Park SJ, Ang XW, Samanta A, Driessen WH, Ntziachristos V, Vasquez KO, Peterson JD, Yun SW, Chang YT.

Chem Commun (Camb). 2014 Jun 25;50(50):6589-91. doi: 10.1039/c4cc02038c.

PMID:
24823600
15.

Oligo(ethylene glycol)-based thermosensitive dendrimers and their tumor accumulation and penetration.

Wu W, Driessen W, Jiang X.

J Am Chem Soc. 2014 Feb 26;136(8):3145-55. doi: 10.1021/ja411457r. Epub 2014 Feb 18.

PMID:
24506735
16.

Bacteriophage Associated Silicon Particles: Design and Characterization of a Novel Theranostic Vector with Improved Payload Carrying Potential.

Srinivasan S, Alexander JF, Driessen WH, Leonard F, Ye H, Liu X, Arap W, Pasqualini R, Ferrari M, Godin B.

J Mater Chem B. 2013 Oct 21;1(39). doi: 10.1039/C3TB20595A.

17.

Mechanism of action and initial evaluation of a membrane active all-D-enantiomer antimicrobial peptidomimetic.

McGrath DM, Barbu EM, Driessen WH, Lasco TM, Tarrand JJ, Okhuysen PC, Kontoyiannis DP, Sidman RL, Pasqualini R, Arap W.

Proc Natl Acad Sci U S A. 2013 Feb 26;110(9):3477-82. doi: 10.1073/pnas.1221924110. Epub 2013 Jan 23.

18.

Multispectral opto-acoustic tomography (MSOT) of the brain and glioblastoma characterization.

Burton NC, Patel M, Morscher S, Driessen WH, Claussen J, Beziere N, Jetzfellner T, Taruttis A, Razansky D, Bednar B, Ntziachristos V.

Neuroimage. 2013 Jan 15;65:522-8. doi: 10.1016/j.neuroimage.2012.09.053. Epub 2012 Sep 28.

PMID:
23026761
19.

A peptidomimetic targeting white fat causes weight loss and improved insulin resistance in obese monkeys.

Barnhart KF, Christianson DR, Hanley PW, Driessen WH, Bernacky BJ, Baze WB, Wen S, Tian M, Ma J, Kolonin MG, Saha PK, Do KA, Hulvat JF, Gelovani JG, Chan L, Arap W, Pasqualini R.

Sci Transl Med. 2011 Nov 9;3(108):108ra112. doi: 10.1126/scitranslmed.3002621.

20.

Enhanced relative biological effectiveness of proton radiotherapy in tumor cells with internalized gold nanoparticles.

Polf JC, Bronk LF, Driessen WH, Arap W, Pasqualini R, Gillin M.

Appl Phys Lett. 2011 May 9;98(19):193702. Epub 2011 May 10.

21.

In vivo anti-tumor effect of expressing p14ARF-TAT using a FGF2-targeted cationic lipid vector.

Niu G, Driessen WH, Sullivan SM, Hughes JA.

Pharm Res. 2011 Apr;28(4):720-30. doi: 10.1007/s11095-010-0353-x. Epub 2011 Jan 19.

PMID:
21246396
22.

Systemic combinatorial peptide selection yields a non-canonical iron-mimicry mechanism for targeting tumors in a mouse model of human glioblastoma.

Staquicini FI, Ozawa MG, Moya CA, Driessen WH, Barbu EM, Nishimori H, Soghomonyan S, Flores LG 2nd, Liang X, Paolillo V, Alauddin MM, Basilion JP, Furnari FB, Bogler O, Lang FF, Aldape KD, Fuller GN, Höök M, Gelovani JG, Sidman RL, Cavenee WK, Pasqualini R, Arap W.

J Clin Invest. 2011 Jan;121(1):161-73. doi: 10.1172/JCI44798. Epub 2010 Dec 22.

23.

On the synergistic effects of ligand-mediated and phage-intrinsic properties during in vivo selection.

Driessen WH, Bronk LF, Edwards JK, Proneth B, Souza GR, Decuzzi P, Pasqualini R, Arap W.

Adv Genet. 2010;69:115-33. doi: 10.1016/S0065-2660(10)69005-0.

PMID:
20807605
24.

An integrated approach for the rational design of nanovectors for biomedical imaging and therapy.

Godin B, Driessen WH, Proneth B, Lee SY, Srinivasan S, Rumbaut R, Arap W, Pasqualini R, Ferrari M, Decuzzi P.

Adv Genet. 2010;69:31-64. doi: 10.1016/S0065-2660(10)69009-8. Review.

25.

Upgrading of sewage treatment plant by sustainable and cost-effective separate treatment of industrial wastewater.

Abma WR, Driessen W, Haarhuis R, van Loosdrecht MC.

Water Sci Technol. 2010;61(7):1715-22. doi: 10.2166/wst.2010.977.

PMID:
20371929
26.

Ligand-directed cancer gene therapy to angiogenic vasculature.

Driessen WHP, Ozawa MG, Arap W, Pasqualini R.

Adv Genet. 2009;67:103-121. doi: 10.1016/S0065-2660(09)67004-8. Review.

PMID:
19914451
27.

Development of peptide-targeted lipoplexes to CXCR4-expressing rat glioma cells and rat proliferating endothelial cells.

Driessen WH, Fujii N, Tamamura H, Sullivan SM.

Mol Ther. 2008 Mar;16(3):516-24. doi: 10.1038/sj.mt.6300388. Epub 2008 Jan 15.

28.

Anaerobic treatment of pulp and paper mill effluents--status quo and new developments.

Habets L, Driessen W.

Water Sci Technol. 2007;55(6):223-30.

PMID:
17486855
29.

Peptide-mediated gene transfer of cationic lipid/plasmid DNA complexes to endothelial cells.

Anwer K, Kao G, Rolland A, Driessen WH, Sullivan SM.

J Drug Target. 2004 May;12(4):215-21.

PMID:
15506170
30.

Conformational and stereochemical flexibility in cadmium(II) complexes of aza-thioether macrocycles.

Glenny MW, van de Water LG, Driessen WL, Reedijk J, Blake AJ, Wilson C, Schröder M.

Dalton Trans. 2004 Jul 7;(13):1953-9. Epub 2004 May 18.

PMID:
15252582
31.

DC-SIGN-specific liposomal targeting and selective intracellular compound delivery to human myeloid dendritic cells: implications for HIV disease.

Gieseler RK, Marquitan G, Hahn MJ, Perdon LA, Driessen WH, Sullivan SM, Scolaro MJ.

Scand J Immunol. 2004 May;59(5):415-24.

32.

Century-known copper salt Cu(OAc)(OMe) proven to be a unique magnetic lattice composed of tetranuclear copper(II) species with a rare binding mode of the acetate anion.

Koval IA, Gamez P, Roubeau O, Driessen WL, Lutz M, Spek AL, Reedijk J.

Inorg Chem. 2003 Feb 10;42(3):868-72. Erratum in: Inorg Chem. 2004 Jan 12;43(1):392.

PMID:
12562201
33.

Ligand-templated four-metal chains dimerize into a unique [Cu(II)(8)] cluster.

Aromí G, Gamez P, Roubeau O, Kooijman H, Spek AL, Driessen WL, Reedijk J.

Angew Chem Int Ed Engl. 2002 Apr 2;41(7):1168-70. No abstract available.

PMID:
12491248
34.

Tuning the recovery of an Rh-containing catalyst with silica-based (poly) amine ion exchangers.

Kramer J, García AR, Driessen WL, Reedijk J.

Chem Commun (Camb). 2001 Dec 7;(23):2420-1.

PMID:
12239995
35.

An unprecedented 1D ladder coordination polymer based on a pentanuclear copper(II) 2,4,6-tris(dipyridin-2-ylamino)-1,3,5-triazine building block.

Gamez P, de Hoog P, Roubeau O, Lutz M, Driessen WL, Spek AL, Reedijk J.

Chem Commun (Camb). 2002 Jul 21;(14):1488-9.

PMID:
12189857
36.

A solvent-controlled switch of manganese complex assemblies with a beta-diketonate-based ligand.

Aromí G, Gamez P, Roubeau O, Berzal PC, Kooijman H, Spek AL, Driessen WL, Reedijk J.

Inorg Chem. 2002 Jul 15;41(14):3673-83.

PMID:
12099871
37.

Formation of Dinuclear Copper(II) Complexes from a Macrocycle with Built-in Pyrazole Groups.

Bode RH, Bol JE, Driessen WL, Hulsbergen FB, Reedijk J, Spek AL.

Inorg Chem. 1999 Mar 22;38(6):1239-1243.

PMID:
11670908
39.
40.

Spontaneous regression of hepatocellular carcinoma.

van Halteren HK, Salemans JM, Peters H, Vreugdenhil G, Driessen WM.

J Hepatol. 1997 Jul;27(1):211-5.

PMID:
9252098
42.

Effectiveness of quadruple therapy using lansoprazole, instead of omeprazole, in curing Helicobacter pylori infection.

de Boer WA, van Etten RJ, Lai JY, Schneeberger PM, van de Wouw BA, Driessen WM.

Helicobacter. 1996 Sep;1(3):145-50.

PMID:
9398895
43.

Long-term follow-up after cure of Helicobacter pylori infection with 4 days of quadruple therapy.

Lai JY, De Boer WA, Driessen WM, Geuskens LM.

Aliment Pharmacol Ther. 1996 Aug;10(4):645-50.

PMID:
8853771
44.

Regional enteritis complicating malignant lymphoma.

Veldman W, van Beek M, Keuning JJ, Driessen WM.

Neth J Med. 1996 Aug;49(2):82-5.

PMID:
8824110
46.

Only four days of quadruple therapy can effectively cure Helicobacter pylori infection.

De Boer WA, Driessen WM, Tytgat GN.

Aliment Pharmacol Ther. 1995 Dec;9(6):633-8.

PMID:
8824650
47.
48.

Resolution of gastric outlet obstruction after eradication of Helicobacter pylori.

de Boer WA, Driessen WM.

J Clin Gastroenterol. 1995 Dec;21(4):329-30. No abstract available.

PMID:
8583113
49.

Increasing incidence of cancer of the sigmoid and ascending colon for men in south-east Netherlands.

Damhuis RA, Coebergh JW, Driessen WM, van der Heijden LH.

Eur J Cancer. 1995 Nov;31A(12):2116-7. No abstract available.

PMID:
8562178
50.

Marking clips for the accurate positioning of self-expandable esophageal stents.

de Boer WA, van Haren F, Driessen WM.

Gastrointest Endosc. 1995 Jul;42(1):73-6. No abstract available.

PMID:
7557183

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