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Items: 45


Insight into microtubule nucleation from tubulin-capping proteins.

Campanacci V, Urvoas A, Cantos-Fernandes S, Aumont-Nicaise M, Arteni AA, Velours C, Valerio-Lepiniec M, Dreier B, Plückthun A, Pilon A, Poüs C, Minard P, Gigant B.

Proc Natl Acad Sci U S A. 2019 May 14;116(20):9859-9864. doi: 10.1073/pnas.1813559116. Epub 2019 Apr 29.


Rapid Selection of High-Affinity Antibody scFv Fragments Using Ribosome Display.

Dreier B, Plückthun A.

Methods Mol Biol. 2018;1827:235-268. doi: 10.1007/978-1-4939-8648-4_13.


A Library-Based Screening Strategy for the Identification of DARPins as Ligands for Receptor-Targeted AAV and Lentiviral Vectors.

Hartmann J, Münch RC, Freiling RT, Schneider IC, Dreier B, Samukange W, Koch J, Seeger MA, Plückthun A, Buchholz CJ.

Mol Ther Methods Clin Dev. 2018 Jul 6;10:128-143. doi: 10.1016/j.omtm.2018.07.001. eCollection 2018 Sep 21.


Adenoviral vector with shield and adapter increases tumor specificity and escapes liver and immune control.

Schmid M, Ernst P, Honegger A, Suomalainen M, Zimmermann M, Braun L, Stauffer S, Thom C, Dreier B, Eibauer M, Kipar A, Vogel V, Greber UF, Medalia O, Plückthun A.

Nat Commun. 2018 Jan 31;9(1):450. doi: 10.1038/s41467-017-02707-6.


Destabilizing an interacting motif strengthens the association of a designed ankyrin repeat protein with tubulin.

Ahmad S, Pecqueur L, Dreier B, Hamdane D, Aumont-Nicaise M, Plückthun A, Knossow M, Gigant B.

Sci Rep. 2016 Jul 6;6:28922. doi: 10.1038/srep28922.


Off-target-free gene delivery by affinity-purified receptor-targeted viral vectors.

Münch RC, Muth A, Muik A, Friedel T, Schmatz J, Dreier B, Trkola A, Plückthun A, Büning H, Buchholz CJ.

Nat Commun. 2015 Feb 10;6:6246. doi: 10.1038/ncomms7246.


Involvement of YAP, TAZ and HSP90 in contact guidance and intercellular junction formation in corneal epithelial cells.

Raghunathan VK, Dreier B, Morgan JT, Tuyen BC, Rose BW, Reilly CM, Russell P, Murphy CJ.

PLoS One. 2014 Oct 7;9(10):e109811. doi: 10.1371/journal.pone.0109811. eCollection 2014.


Structure of a kinesin-tubulin complex and implications for kinesin motility.

Gigant B, Wang W, Dreier B, Jiang Q, Pecqueur L, Plückthun A, Wang C, Knossow M.

Nat Struct Mol Biol. 2013 Aug;20(8):1001-7. doi: 10.1038/nsmb.2624. Epub 2013 Jul 21.


Substratum compliance modulates corneal fibroblast to myofibroblast transformation.

Dreier B, Thomasy SM, Mendonsa R, Raghunathan VK, Russell P, Murphy CJ.

Invest Ophthalmol Vis Sci. 2013 Aug 28;54(8):5901-7. doi: 10.1167/iovs.12-11575.


Early responses of vascular endothelial cells to topographic cues.

Dreier B, Gasiorowski JZ, Morgan JT, Nealey PF, Russell P, Murphy CJ.

Am J Physiol Cell Physiol. 2013 Aug 1;305(3):C290-8. doi: 10.1152/ajpcell.00264.2012. Epub 2013 May 22.


Conformation-dependent recognition of HIV gp120 by designed ankyrin repeat proteins provides access to novel HIV entry inhibitors.

Mann A, Friedrich N, Krarup A, Weber J, Stiegeler E, Dreier B, Pugach P, Robbiani M, Riedel T, Moehle K, Robinson JA, Rusert P, Plückthun A, Trkola A.

J Virol. 2013 May;87(10):5868-81. doi: 10.1128/JVI.00152-13. Epub 2013 Mar 13.


Development of a generic adenovirus delivery system based on structure-guided design of bispecific trimeric DARPin adapters.

Dreier B, Honegger A, Hess C, Nagy-Davidescu G, Mittl PR, Grütter MG, Belousova N, Mikheeva G, Krasnykh V, Plückthun A.

Proc Natl Acad Sci U S A. 2013 Mar 5;110(10):E869-77. doi: 10.1073/pnas.1213653110. Epub 2013 Feb 19.


Role of substratum stiffness in modulating genes associated with extracellular matrix and mechanotransducers YAP and TAZ.

Raghunathan VK, Morgan JT, Dreier B, Reilly CM, Thomasy SM, Wood JA, Ly I, Tuyen BC, Hughbanks M, Murphy CJ, Russell P.

Invest Ophthalmol Vis Sci. 2013 Jan 14;54(1):378-86. doi: 10.1167/iovs.12-11007.


Focal adhesion kinase knockdown modulates the response of human corneal epithelial cells to topographic cues.

Dreier B, Raghunathan VK, Russell P, Murphy CJ.

Acta Biomater. 2012 Dec;8(12):4285-94. doi: 10.1016/j.actbio.2012.07.004. Epub 2012 Jul 17.


Design and characterization of modular scaffolds for tubulin assembly.

Mignot I, Pecqueur L, Dorléans A, Karuppasamy M, Ravelli RB, Dreier B, Plückthun A, Knossow M, Gigant B.

J Biol Chem. 2012 Sep 7;287(37):31085-94. doi: 10.1074/jbc.M112.383869. Epub 2012 Jul 12.


A designed ankyrin repeat protein selected to bind to tubulin caps the microtubule plus end.

Pecqueur L, Duellberg C, Dreier B, Jiang Q, Wang C, Plückthun A, Surrey T, Gigant B, Knossow M.

Proc Natl Acad Sci U S A. 2012 Jul 24;109(30):12011-6. doi: 10.1073/pnas.1204129109. Epub 2012 Jul 9.


Rapid selection of high-affinity binders using ribosome display.

Dreier B, Plückthun A.

Methods Mol Biol. 2012;805:261-86. doi: 10.1007/978-1-61779-379-0_15.


Her2-specific multivalent adapters confer designed tropism to adenovirus for gene targeting.

Dreier B, Mikheeva G, Belousova N, Parizek P, Boczek E, Jelesarov I, Forrer P, Plückthun A, Krasnykh V.

J Mol Biol. 2011 Jan 14;405(2):410-26. doi: 10.1016/j.jmb.2010.10.040. Epub 2010 Nov 5.


Ribosome display: a technology for selecting and evolving proteins from large libraries.

Dreier B, Plückthun A.

Methods Mol Biol. 2011;687:283-306. doi: 10.1007/978-1-60761-944-4_21.


Designed ankyrin repeat proteins: a novel tool for testing epidermal growth factor receptor 2 expression in breast cancer.

Theurillat JP, Dreier B, Nagy-Davidescu G, Seifert B, Behnke S, Zürrer-Härdi U, Ingold F, Plückthun A, Moch H.

Mod Pathol. 2010 Sep;23(9):1289-97. doi: 10.1038/modpathol.2010.103. Epub 2010 May 21.


Efficient tumor targeting with high-affinity designed ankyrin repeat proteins: effects of affinity and molecular size.

Zahnd C, Kawe M, Stumpp MT, de Pasquale C, Tamaskovic R, Nagy-Davidescu G, Dreier B, Schibli R, Binz HK, Waibel R, Plückthun A.

Cancer Res. 2010 Feb 15;70(4):1595-605. doi: 10.1158/0008-5472.CAN-09-2724. Epub 2010 Feb 2.


Crystal structure and function of a DARPin neutralizing inhibitor of lactococcal phage TP901-1: comparison of DARPin and camelid VHH binding mode.

Veesler D, Dreier B, Blangy S, Lichière J, Tremblay D, Moineau S, Spinelli S, Tegoni M, Plückthun A, Campanacci V, Cambillau C.

J Biol Chem. 2009 Oct 30;284(44):30718-26. doi: 10.1074/jbc.M109.037812. Epub 2009 Sep 9.


Purification and enzymological characterization of murine neurotrypsin.

Reif R, Sales S, Dreier B, Lüscher D, Wölfel J, Gisler C, Baici A, Kunz B, Sonderegger P.

Protein Expr Purif. 2008 Sep;61(1):13-21. doi: 10.1016/j.pep.2008.06.003. Epub 2008 Jun 8.


Specific cleavage of agrin by neurotrypsin, a synaptic protease linked to mental retardation.

Reif R, Sales S, Hettwer S, Dreier B, Gisler C, Wölfel J, Lüscher D, Zurlinden A, Stephan A, Ahmed S, Baici A, Ledermann B, Kunz B, Sonderegger P.

FASEB J. 2007 Nov;21(13):3468-78. Epub 2007 Jun 22.


Development of zinc finger domains for recognition of the 5'-CNN-3' family DNA sequences and their use in the construction of artificial transcription factors.

Dreier B, Fuller RP, Segal DJ, Lund CV, Blancafort P, Huber A, Koksch B, Barbas CF 3rd.

J Biol Chem. 2005 Oct 21;280(42):35588-97. Epub 2005 Aug 17.


Overexpression of hypoxia-inducible factor 1alpha indicates diminished response to radiotherapy and unfavorable prognosis in patients receiving radical radiotherapy for cervical cancer.

Bachtiary B, Schindl M, Pötter R, Dreier B, Knocke TH, Hainfellner JA, Horvat R, Birner P.

Clin Cancer Res. 2003 Jun;9(6):2234-40.


Evaluation of a modular strategy for the construction of novel polydactyl zinc finger DNA-binding proteins.

Segal DJ, Beerli RR, Blancafort P, Dreier B, Effertz K, Huber A, Koksch B, Lund CV, Magnenat L, Valente D, Barbas CF 3rd.

Biochemistry. 2003 Feb 25;42(7):2137-48.


Impact of multiple HPV infection on response to treatment and survival in patients receiving radical radiotherapy for cervical cancer.

Bachtiary B, Obermair A, Dreier B, Birner P, Breitenecker G, Knocke TH, Selzer E, Pötter R.

Int J Cancer. 2002 Nov 20;102(3):237-43.


Signal-amplified colorimetric in situ hybridization for assessment of human papillomavirus infection in cervical lesions.

Birner P, Bachtiary B, Dreier B, Schindl M, Joura EA, Breitenecker G, Oberhuber G.

Mod Pathol. 2001 Jul;14(7):702-9.


Extracellular accumulation of bioactive substances during preparation and storage of various platelet concentrates.

Edvardsen L, Taaning E, Dreier B, Christensen LD, Mynster T, Nielsen HJ.

Am J Hematol. 2001 Jul;67(3):157-62.


Development of zinc finger domains for recognition of the 5'-ANN-3' family of DNA sequences and their use in the construction of artificial transcription factors.

Dreier B, Beerli RR, Segal DJ, Flippin JD, Barbas CF 3rd.

J Biol Chem. 2001 Aug 3;276(31):29466-78. Epub 2001 May 4.


Impact of human papillomavirus infection on the expression of the KAI1 metastasis suppressor protein in invasive cervical cancer.

Schindl M, Bachtiary B, Dreier B, Birner P, Latinovic L, Karner B, Breitenecker G, Oberhuber G.

Cancer Lett. 2001 Jan 26;162(2):261-6.


Insights into the molecular recognition of the 5'-GNN-3' family of DNA sequences by zinc finger domains.

Dreier B, Segal DJ, Barbas CF 3rd.

J Mol Biol. 2000 Nov 3;303(4):489-502.


Chemically regulated zinc finger transcription factors.

Beerli RR, Schopfer U, Dreier B, Barbas CF 3rd.

J Biol Chem. 2000 Oct 20;275(42):32617-27.


Positive and negative regulation of endogenous genes by designed transcription factors.

Beerli RR, Dreier B, Barbas CF 3rd.

Proc Natl Acad Sci U S A. 2000 Feb 15;97(4):1495-500.


Fragrances and other materials in deodorants: search for potentially sensitizing molecules using combined GC-MS and structure activity relationship (SAR) analysis.

Rastogi SC, Lepoittevin JP, Johansen JD, Frosch PJ, Menné T, Bruze M, Dreier B, Andersen KE, White IR.

Contact Dermatitis. 1998 Dec;39(6):293-303.


Deodorants: a clinical provocation study in fragrance-sensitive individuals.

Johansen JD, Rastogi SC, Bruze M, Andersen KE, Frosch P, Dreier B, Lepoittevin JP, White I, Menné T.

Contact Dermatitis. 1998 Oct;39(4):161-5.


The repeated open application test: suggestions for a scale of evaluation.

Johansen JD, Bruze M, Andersen KE, Frosch PJ, Dreier B, White IR, Rastogi S, Lepoittevin JP, Menné T.

Contact Dermatitis. 1998 Aug;39(2):95-6. No abstract available.


Deodorants on the European market: quantitative chemical analysis of 21 fragrances.

Rastogi SC, Johansen JD, Frosch P, Menné T, Bruze M, Lepoittevin JP, Dreier B, Andersen KE, White IR.

Contact Dermatitis. 1998 Jan;38(1):29-35.


[Papular mucinosis--successful therapy with plasmapheresis].

Dreier B, Hammad-Zulfoghari D, Beiteke U, Frosch PJ.

Hautarzt. 1997 Sep;48(9):648-52. German.


A 32-kDa proteolytic fragment of transcription factor Stat3 is capable of specific DNA binding.

Dreier B, Fritz S, Volkert G, Brachvogel B, Lottspeich F, Fey GH.

J Biol Chem. 1997 Aug 29;272(35):22118-24.


[Prurigo pigmentosa].

Rabenhorst S, Dreier B, Metze D, Hildebrand A, Frosch PJ.

Hautarzt. 1997 Jun;48(6):406-9. German.


Isolation of two interleukin-6 response element binding proteins from acute phase rat livers.

Ripperger J, Fritz S, Richter K, Dreier B, Schneider K, Löchner K, Marschalek R, Hocke G, Lottspeich F, Fey GH.

Ann N Y Acad Sci. 1995 Jul 21;762:252-60; discussion 260-1.


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