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Items: 29


RNA-Peptide nanoplexes drug DNA damage pathways in high-grade serous ovarian tumors.

Dreaden EC, Kong YW, Quadir MA, Correa S, Suárez-López L, Barberio AE, Hwang MK, Shi AC, Oberlton B, Gallagher PN, Shopsowitz KE, Elias KM, Yaffe MB, Hammond PT.

Bioeng Transl Med. 2018 Jan 19;3(1):26-36. doi: 10.1002/btm2.10086. eCollection 2018 Jan.


Cellular uptake of nanoparticles: journey inside the cell.

Behzadi S, Serpooshan V, Tao W, Hamaly MA, Alkawareek MY, Dreaden EC, Brown D, Alkilany AM, Farokhzad OC, Mahmoudi M.

Chem Soc Rev. 2017 Jul 17;46(14):4218-4244. doi: 10.1039/c6cs00636a. Review.


Highly scalable, closed-loop synthesis of drug-loaded, layer-by-layer nanoparticles.

Correa S, Choi KY, Dreaden EC, Renggli K, Shi A, Gu L, Shopsowitz KE, Quadir MA, Ben-Akiva E, Hammond PT.

Adv Funct Mater. 2016 Feb 16;26(7):991-1003. Epub 2016 Jan 3.


Designer Dual Therapy Nanolayered Implant Coatings Eradicate Biofilms and Accelerate Bone Tissue Repair.

Min J, Choi KY, Dreaden EC, Padera RF, Braatz RD, Spector M, Hammond PT.

ACS Nano. 2016 Apr 26;10(4):4441-50. doi: 10.1021/acsnano.6b00087. Epub 2016 Mar 2.


Engineering nanolayered particles for modular drug delivery.

Correa S, Dreaden EC, Gu L, Hammond PT.

J Control Release. 2016 Oct 28;240:364-386. doi: 10.1016/j.jconrel.2016.01.040. Epub 2016 Jan 22. Review.


Periodic-shRNA molecules are capable of gene silencing, cytotoxicity and innate immune activation in cancer cells.

Shopsowitz KE, Wu C, Liu G, Dreaden EC, Hammond PT.

Nucleic Acids Res. 2016 Jan 29;44(2):545-57. doi: 10.1093/nar/gkv1488. Epub 2015 Dec 23.


A Multi-RNAi Microsponge Platform for Simultaneous Controlled Delivery of Multiple Small Interfering RNAs.

Roh YH, Deng JZ, Dreaden EC, Park JH, Yun DS, Shopsowitz KE, Hammond PT.

Angew Chem Int Ed Engl. 2016 Mar 1;55(10):3347-51. doi: 10.1002/anie.201508978. Epub 2015 Dec 22.


Influence of pH and Surface Chemistry on Poly(L-lysine) Adsorption onto Solid Supports Investigated by Quartz Crystal Microbalance with Dissipation Monitoring.

Choi JH, Kim SO, Linardy E, Dreaden EC, Zhdanov VP, Hammond PT, Cho NJ.

J Phys Chem B. 2015 Aug 20;119(33):10554-65. doi: 10.1021/acs.jpcb.5b01553. Epub 2015 Aug 7.


Tumor-Targeted Synergistic Blockade of MAPK and PI3K from a Layer-by-Layer Nanoparticle.

Dreaden EC, Kong YW, Morton SW, Correa S, Choi KY, Shopsowitz KE, Renggli K, Drapkin R, Yaffe MB, Hammond PT.

Clin Cancer Res. 2015 Oct 1;21(19):4410-9. doi: 10.1158/1078-0432.CCR-15-0013. Epub 2015 Jun 1.


Adsorption of hyaluronic acid on solid supports: role of pH and surface chemistry in thin film self-assembly.

Choi JH, Kim SO, Linardy E, Dreaden EC, Zhdanov VP, Hammond PT, Cho NJ.

J Colloid Interface Sci. 2015 Jun 15;448:197-207. doi: 10.1016/j.jcis.2015.01.060. Epub 2015 Feb 11.


Redox-responsive branched-bottlebrush polymers for in vivo MRI and fluorescence imaging.

Sowers MA, McCombs JR, Wang Y, Paletta JT, Morton SW, Dreaden EC, Boska MD, Ottaviani MF, Hammond PT, Rajca A, Johnson JA.

Nat Commun. 2014 Nov 18;5:5460. doi: 10.1038/ncomms6460.


Layer-by-layer assembled antisense DNA microsponge particles for efficient delivery of cancer therapeutics.

Roh YH, Lee JB, Shopsowitz KE, Dreaden EC, Morton SW, Poon Z, Hong J, Yamin I, Bonner DK, Hammond PT.

ACS Nano. 2014 Oct 28;8(10):9767-80. doi: 10.1021/nn502596b. Epub 2014 Oct 14.


Bimodal tumor-targeting from microenvironment responsive hyaluronan layer-by-layer (LbL) nanoparticles.

Dreaden EC, Morton SW, Shopsowitz KE, Choi JH, Deng ZJ, Cho NJ, Hammond PT.

ACS Nano. 2014 Aug 26;8(8):8374-82. doi: 10.1021/nn502861t. Epub 2014 Aug 11.


The optical, photothermal, and facile surface chemical properties of gold and silver nanoparticles in biodiagnostics, therapy, and drug delivery.

Austin LA, Mackey MA, Dreaden EC, El-Sayed MA.

Arch Toxicol. 2014 Jul;88(7):1391-417. doi: 10.1007/s00204-014-1245-3. Epub 2014 Jun 4. Review.


A nanoparticle-based combination chemotherapy delivery system for enhanced tumor killing by dynamic rewiring of signaling pathways.

Morton SW, Lee MJ, Deng ZJ, Dreaden EC, Siouve E, Shopsowitz KE, Shah NJ, Yaffe MB, Hammond PT.

Sci Signal. 2014 May 13;7(325):ra44. doi: 10.1126/scisignal.2005261.


A convergent synthetic platform for single-nanoparticle combination cancer therapy: ratiometric loading and controlled release of cisplatin, doxorubicin, and camptothecin.

Liao L, Liu J, Dreaden EC, Morton SW, Shopsowitz KE, Hammond PT, Johnson JA.

J Am Chem Soc. 2014 Apr 23;136(16):5896-9. doi: 10.1021/ja502011g. Epub 2014 Apr 11.


P-glycoprotein-dependent trafficking of nanoparticle-drug conjugates.

Dreaden EC, Raji IO, Austin LA, Fathi S, Mwakwari SC, Humphries WH 4th, Kang B, Oyelere AK, El-Sayed MA.

Small. 2014 May 14;10(9):1719-23. doi: 10.1002/smll.201303190. Epub 2014 Feb 25. No abstract available.


Layer-by-layer nanoparticles for systemic codelivery of an anticancer drug and siRNA for potential triple-negative breast cancer treatment.

Deng ZJ, Morton SW, Ben-Akiva E, Dreaden EC, Shopsowitz KE, Hammond PT.

ACS Nano. 2013 Nov 26;7(11):9571-84. doi: 10.1021/nn4047925. Epub 2013 Oct 21.


Size matters: gold nanoparticles in targeted cancer drug delivery.

Dreaden EC, Austin LA, Mackey MA, El-Sayed MA.

Ther Deliv. 2012 Apr;3(4):457-78. Review.


Small molecule-gold nanorod conjugates selectively target and induce macrophage cytotoxicity towards breast cancer cells.

Dreaden EC, Mwakwari SC, Austin LA, Kieffer MJ, Oyelere AK, El-Sayed MA.

Small. 2012 Sep 24;8(18):2819-22. doi: 10.1002/smll.201200333. Epub 2012 Jul 6.


Antiandrogen gold nanoparticles dual-target and overcome treatment resistance in hormone-insensitive prostate cancer cells.

Dreaden EC, Gryder BE, Austin LA, Tene Defo BA, Hayden SC, Pi M, Quarles LD, Oyelere AK, El-Sayed MA.

Bioconjug Chem. 2012 Aug 15;23(8):1507-12. doi: 10.1021/bc300158k. Epub 2012 Jul 12.


Detecting and destroying cancer cells in more than one way with noble metals and different confinement properties on the nanoscale.

Dreaden EC, El-Sayed MA.

Acc Chem Res. 2012 Nov 20;45(11):1854-65. doi: 10.1021/ar2003122. Epub 2012 Apr 30.


The golden age: gold nanoparticles for biomedicine.

Dreaden EC, Alkilany AM, Huang X, Murphy CJ, El-Sayed MA.

Chem Soc Rev. 2012 Apr 7;41(7):2740-79. doi: 10.1039/c1cs15237h. Epub 2011 Nov 22. Review.


Tailoring plasmonic and electrostatic field effects to maximize solar energy conversion by bacteriorhodopsin, the other natural photosynthetic system.

Yen CW, Hayden SC, Dreaden EC, Szymanski P, El-Sayed MA.

Nano Lett. 2011 Sep 14;11(9):3821-6. doi: 10.1021/nl2018959. Epub 2011 Aug 3.


Beating cancer in multiple ways using nanogold.

Dreaden EC, Mackey MA, Huang X, Kang B, El-Sayed MA.

Chem Soc Rev. 2011 Jul;40(7):3391-404. doi: 10.1039/c0cs00180e. Epub 2011 May 31. Review.


Tamoxifen-poly(ethylene glycol)-thiol gold nanoparticle conjugates: enhanced potency and selective delivery for breast cancer treatment.

Dreaden EC, Mwakwari SC, Sodji QH, Oyelere AK, El-Sayed MA.

Bioconjug Chem. 2009 Dec;20(12):2247-53. doi: 10.1021/bc9002212.


The dependence of the plasmon field induced nonradiative electronic relaxation mechanisms on the gold shell thickness in vertically aligned CdTe-Au core-shell nanorods.

Neretina S, Dreaden EC, Qian W, El-Sayed MA, Hughes RA, Preston JS, Mascher P.

Nano Lett. 2009 Nov;9(11):3772-9. doi: 10.1021/nl901960w.


Exciton lifetime tuning by changing the plasmon field orientation with respect to the exciton transition moment direction: CdTe-Au core-shell nanorods.

Neretina S, Qian W, Dreaden EC, El-Sayed MA, Hughes RA, Preston JS, Mascher P.

Nano Lett. 2009 Mar;9(3):1242-8. doi: 10.1021/nl900183m.


Gold nanorod assisted near-infrared plasmonic photothermal therapy (PPTT) of squamous cell carcinoma in mice.

Dickerson EB, Dreaden EC, Huang X, El-Sayed IH, Chu H, Pushpanketh S, McDonald JF, El-Sayed MA.

Cancer Lett. 2008 Sep 28;269(1):57-66. doi: 10.1016/j.canlet.2008.04.026. Epub 2008 Jun 9.

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