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Items: 1 to 50 of 189

1.

Harmonization study between three laboratories for expression of malaria vaccine clinical trial IgG antibody ELISA data in µg/mL.

Labbé GM, Miura K, Silk SE, Gu W, Moon JE, Jin J, Payne RO, Fay MP, Dutta S, Long CA, Draper SJ.

Malar J. 2019 Sep 2;18(1):300. doi: 10.1186/s12936-019-2935-3.

2.

Design of a basigin-mimicking inhibitor targeting the malaria invasion protein RH5.

Warszawski S, Dekel E, Campeotto I, Marshall JM, Wright KE, Lyth O, Knop O, Regev-Rudzki N, Higgins MK, Draper SJ, Baum J, Fleishman SJ.

Proteins. 2019 Jul 20. doi: 10.1002/prot.25786. [Epub ahead of print]

PMID:
31325330
3.

Functional Comparison of Blood-Stage Plasmodium falciparum Malaria Vaccine Candidate Antigens.

Illingworth JJ, Alanine DG, Brown R, Marshall JM, Bartlett HE, Silk SE, Labbé GM, Quinkert D, Cho JS, Wendler JP, Pattinson DJ, Barfod L, Douglas AD, Shea MW, Wright KE, de Cassan SC, Higgins MK, Draper SJ.

Front Immunol. 2019 Jun 4;10:1254. doi: 10.3389/fimmu.2019.01254. eCollection 2019.

4.

Rapid and iterative genome editing in the malaria parasite Plasmodium knowlesi provides new tools for P. vivax research.

Mohring F, Hart MN, Rawlinson TA, Henrici R, Charleston JA, Diez Benavente E, Patel A, Hall J, Almond N, Campino S, Clark TG, Sutherland CJ, Baker DA, Draper SJ, Moon RW.

Elife. 2019 Jun 17;8. pii: e45829. doi: 10.7554/eLife.45829.

5.

Human Antibodies that Slow Erythrocyte Invasion Potentiate Malaria-Neutralizing Antibodies.

Alanine DGW, Quinkert D, Kumarasingha R, Mehmood S, Donnellan FR, Minkah NK, Dadonaite B, Diouf A, Galaway F, Silk SE, Jamwal A, Marshall JM, Miura K, Foquet L, Elias SC, Labbé GM, Douglas AD, Jin J, Payne RO, Illingworth JJ, Pattinson DJ, Pulido D, Williams BG, de Jongh WA, Wright GJ, Kappe SHI, Robinson CV, Long CA, Crabb BS, Gilson PR, Higgins MK, Draper SJ.

Cell. 2019 Jun 27;178(1):216-228.e21. doi: 10.1016/j.cell.2019.05.025. Epub 2019 Jun 13.

6.

Influence of PEGylation on the Strength of Protein Surface Salt Bridges.

Xiao Q, Draper SRE, Smith MS, Brown N, Pugmire NAB, Ashton DS, Carter AJ, Lawrence EEK, Price JL.

ACS Chem Biol. 2019 Jul 19;14(7):1652-1659. doi: 10.1021/acschembio.9b00432. Epub 2019 Jun 24.

PMID:
31188563
7.

Multinuclear Ru(ii) and Ir(iii) decorated tetraphenylporphyrins as efficient PDT agents.

Cabrera-González J, Soriano J, Conway-Kenny R, Wang J, Lu Y, Zhao J, Nogués C, Draper SM.

Biomater Sci. 2019 Aug 1;7(8):3287-3296. doi: 10.1039/c9bm00192a. Epub 2019 Jun 12.

PMID:
31187805
8.

Divergent roles for the RH5 complex components, CyRPA and RIPR in human-infective malaria parasites.

Knuepfer E, Wright KE, Kumar Prajapati S, Rawlinson TA, Mohring F, Koch M, Lyth OR, Howell SA, Villasis E, Snijders AP, Moon RW, Draper SJ, Rosanas-Urgell A, Higgins MK, Baum J, Holder AA.

PLoS Pathog. 2019 Jun 11;15(6):e1007809. doi: 10.1371/journal.ppat.1007809. eCollection 2019 Jun.

9.

Structural basis for inhibition of Plasmodium vivax invasion by a broadly neutralizing vaccine-induced human antibody.

Rawlinson TA, Barber NM, Mohring F, Cho JS, Kosaisavee V, Gérard SF, Alanine DGW, Labbé GM, Elias SC, Silk SE, Quinkert D, Jin J, Marshall JM, Payne RO, Minassian AM, Russell B, Rénia L, Nosten FH, Moon RW, Higgins MK, Draper SJ.

Nat Microbiol. 2019 Sep;4(9):1497-1507. doi: 10.1038/s41564-019-0462-1. Epub 2019 May 27.

PMID:
31133755
10.

The Influence of Body Mass and Height on Equine Hoof Conformation and Symmetry.

Leśniak K, Whittington L, Mapletoft S, Mitchell J, Hancox K, Draper S, Williams J.

J Equine Vet Sci. 2019 Jun;77:43-49. doi: 10.1016/j.jevs.2019.02.013. Epub 2019 Feb 21.

PMID:
31133315
11.

A defined mechanistic correlate of protection against Plasmodium falciparum malaria in non-human primates.

Douglas AD, Baldeviano GC, Jin J, Miura K, Diouf A, Zenonos ZA, Ventocilla JA, Silk SE, Marshall JM, Alanine DGW, Wang C, Edwards NJ, Leiva KP, Gomez-Puerta LA, Lucas CM, Wright GJ, Long CA, Royal JM, Draper SJ.

Nat Commun. 2019 Apr 26;10(1):1953. doi: 10.1038/s41467-019-09894-4.

12.

Therapeutic Monoclonal Antibodies for Ebola Virus Infection Derived from Vaccinated Humans.

Rijal P, Elias SC, Machado SR, Xiao J, Schimanski L, O'Dowd V, Baker T, Barry E, Mendelsohn SC, Cherry CJ, Jin J, Labbé GM, Donnellan FR, Rampling T, Dowall S, Rayner E, Findlay-Wilson S, Carroll M, Guo J, Xu XN, Huang KA, Takada A, Burgess G, McMillan D, Popplewell A, Lightwood DJ, Draper SJ, Townsend AR.

Cell Rep. 2019 Apr 2;27(1):172-186.e7. doi: 10.1016/j.celrep.2019.03.020.

13.

SnoopLigase peptide-peptide conjugation enables modular vaccine assembly.

Andersson AC, Buldun CM, Pattinson DJ, Draper SJ, Howarth M.

Sci Rep. 2019 Mar 15;9(1):4625. doi: 10.1038/s41598-019-40985-w.

14.

Infection-Induced Resistance to Experimental Cerebral Malaria Is Dependent Upon Secreted Antibody-Mediated Inhibition of Pathogenic CD8+ T Cell Responses.

Shaw TN, Inkson CA, Villegas-Mendez A, Pattinson DJ, Strangward P, Else KJ, Draper SJ, Zeef LAH, Couper KN.

Front Immunol. 2019 Feb 19;10:248. doi: 10.3389/fimmu.2019.00248. eCollection 2019.

15.

The effect of uncertain bottom friction on estimates of tidal current power.

Kreitmair MJ, Draper S, Borthwick AGL, van den Bremer TS.

R Soc Open Sci. 2019 Jan 9;6(1):180941. doi: 10.1098/rsos.180941. eCollection 2019 Jan.

16.

Transverse motion instability of a submerged moored buoy.

Orszaghova J, Wolgamot H, Draper S, Eatock Taylor R, Taylor PH, Rafiee AA.

Proc Math Phys Eng Sci. 2019 Jan;475(2221):20180459. doi: 10.1098/rspa.2018.0459. Epub 2019 Jan 9.

PMID:
30760952
17.

Antibody Responses to Antigenic Targets of Recent Exposure Are Associated With Low-Density Parasitemia in Controlled Human Plasmodium falciparum Infections.

van den Hoogen LL, Walk J, Oulton T, Reuling IJ, Reiling L, Beeson JG, Coppel RL, Singh SK, Draper SJ, Bousema T, Drakeley C, Sauerwein R, Tetteh KKA.

Front Microbiol. 2019 Jan 16;9:3300. doi: 10.3389/fmicb.2018.03300. eCollection 2018.

18.

Antibody responses to merozoite antigens after natural Plasmodium falciparum infection: kinetics and longevity in absence of re-exposure.

Yman V, White MT, Asghar M, Sundling C, Sondén K, Draper SJ, Osier FHA, Färnert A.

BMC Med. 2019 Jan 30;17(1):22. doi: 10.1186/s12916-019-1255-3.

19.

Characterization of Polysaccharides from Feijoa Fruits ( Acca sellowiana Berg.) and Their Utilization as Growth Substrates by Gut Commensal Bacteroides Species.

Bell TJ, Draper SL, Centanni M, Carnachan SM, Tannock GW, Sims IM.

J Agric Food Chem. 2018 Dec 19;66(50):13277-13284. doi: 10.1021/acs.jafc.8b05080. Epub 2018 Dec 5.

PMID:
30516980
20.

Stapling of two PEGylated side chains increases the conformational stability of the WW domain via an entropic effect.

Xiao Q, Bécar NA, Brown NP, Smith MS, Stern KL, Draper SRE, Thompson KP, Price JL.

Org Biomol Chem. 2018 Nov 28;16(46):8933-8939. doi: 10.1039/c8ob02535e.

PMID:
30444518
21.

A simian-adenovirus-vectored rabies vaccine suitable for thermostabilisation and clinical development for low-cost single-dose pre-exposure prophylaxis.

Wang C, Dulal P, Zhou X, Xiang Z, Goharriz H, Banyard A, Green N, Brunner L, Ventura R, Collin N, Draper SJ, Hill AVS, Ashfield R, Fooks AR, Ertl HC, Douglas AD.

PLoS Negl Trop Dis. 2018 Oct 29;12(10):e0006870. doi: 10.1371/journal.pntd.0006870. eCollection 2018 Oct.

22.

Correction: Kinetics of antibody responses to PfRH5-complex antigens in Ghanaian children with Plasmodium falciparum malaria.

Partey FD, Castberg FC, Sarbah EW, Silk SE, Awandare GA, Draper SJ, Opoku N, Kweku M, Ofori MF, Hviid L, Barfod L.

PLoS One. 2018 Sep 17;13(9):e0204452. doi: 10.1371/journal.pone.0204452. eCollection 2018.

23.

Production, quality control, stability, and potency of cGMP-produced Plasmodium falciparum RH5.1 protein vaccine expressed in Drosophila S2 cells.

Jin J, Tarrant RD, Bolam EJ, Angell-Manning P, Soegaard M, Pattinson DJ, Dulal P, Silk SE, Marshall JM, Dabbs RA, Nugent FL, Barrett JR, Hjerrild KA, Poulsen L, Jørgensen T, Brenner T, Baleanu IN, Parracho HM, Tahiri-Alaoui A, Whale G, Moyle S, Payne RO, Minassian AM, Higgins MK, Detmers FJ, Lawrie AM, Douglas AD, Smith R, de Jongh WA, Berrie E, Ashfield R, Draper SJ.

NPJ Vaccines. 2018 Aug 17;3:32. doi: 10.1038/s41541-018-0071-7. eCollection 2018.

24.

Erythroferrone inhibits the induction of hepcidin by BMP6.

Arezes J, Foy N, McHugh K, Sawant A, Quinkert D, Terraube V, Brinth A, Tam M, LaVallie ER, Taylor S, Armitage AE, Pasricha SR, Cunningham O, Lambert M, Draper SJ, Jasuja R, Drakesmith H.

Blood. 2018 Oct 4;132(14):1473-1477. doi: 10.1182/blood-2018-06-857995. Epub 2018 Aug 10.

25.

Chemistry of 4-[(4-bromophenyl)ethynyl]pyridine at metal surfaces studied by STM.

Ren J, Larkin E, Delaney C, Song Y, Jin X, Amirjalayer S, Bakker A, Du S, Gao H, Zhang YY, Draper SM, Fuchs H.

Chem Commun (Camb). 2018 Aug 16;54(67):9305-9308. doi: 10.1039/c8cc03986k.

PMID:
30069558
26.

Engineering a Rugged Nanoscaffold To Enhance Plug-and-Display Vaccination.

Bruun TUJ, Andersson AC, Draper SJ, Howarth M.

ACS Nano. 2018 Sep 25;12(9):8855-8866. doi: 10.1021/acsnano.8b02805. Epub 2018 Jul 26.

27.

Malaria Vaccines: Recent Advances and New Horizons.

Draper SJ, Sack BK, King CR, Nielsen CM, Rayner JC, Higgins MK, Long CA, Seder RA.

Cell Host Microbe. 2018 Jul 11;24(1):43-56. doi: 10.1016/j.chom.2018.06.008. Review.

28.

Kinetics of antibody responses to PfRH5-complex antigens in Ghanaian children with Plasmodium falciparum malaria.

Partey FD, Castberg FC, Sarbah EW, Silk SE, Awandare GA, Draper SJ, Opoku N, Kweku M, Ofori MF, Hviid L, Barfod L.

PLoS One. 2018 Jun 8;13(6):e0198371. doi: 10.1371/journal.pone.0198371. eCollection 2018. Erratum in: PLoS One. 2018 Sep 17;13(9):e0204452.

29.

A new site of attack for a malaria vaccine.

Draper SJ, Higgins MK.

Nat Med. 2018 Apr 10;24(4):382-383. doi: 10.1038/nm.4533. No abstract available.

PMID:
29634679
30.

Plasmodium falciparum Liver Stage Infection and Transition to Stable Blood Stage Infection in Liver-Humanized and Blood-Humanized FRGN KO Mice Enables Testing of Blood Stage Inhibitory Antibodies (Reticulocyte-Binding Protein Homolog 5) In Vivo.

Foquet L, Schafer C, Minkah NK, Alanine DGW, Flannery EL, Steel RWJ, Sack BK, Camargo N, Fishbaugher M, Betz W, Nguyen T, Billman ZP, Wilson EM, Bial J, Murphy SC, Draper SJ, Mikolajczak SA, Kappe SHI.

Front Immunol. 2018 Mar 14;9:524. doi: 10.3389/fimmu.2018.00524. eCollection 2018.

31.

Exploiting coumarin-6 as ancillary ligands in 1,10-phenanthroline Ir(iii) complexes: generating triplet photosensitisers with high upconversion capabilities.

Lu Y, Conway-Kenny R, Wang J, Cui X, Zhao J, Draper SM.

Dalton Trans. 2018 Jul 14;47(26):8585-8589. doi: 10.1039/c8dt00231b. Epub 2018 Feb 12.

PMID:
29431810
32.

Novel ruthenium and iridium complexes of N-substituted carbazole as triplet photosensitisers.

Wang J, Lu Y, McCarthy W, Conway-Kenny R, Twamley B, Zhao J, Draper SM.

Chem Commun (Camb). 2018 Jan 25;54(9):1073-1076. doi: 10.1039/c7cc08535d.

PMID:
29327030
33.

Human vaccination against RH5 induces neutralizing antimalarial antibodies that inhibit RH5 invasion complex interactions.

Payne RO, Silk SE, Elias SC, Miura K, Diouf A, Galaway F, de Graaf H, Brendish NJ, Poulton ID, Griffiths OJ, Edwards NJ, Jin J, Labbé GM, Alanine DG, Siani L, Di Marco S, Roberts R, Green N, Berrie E, Ishizuka AS, Nielsen CM, Bardelli M, Partey FD, Ofori MF, Barfod L, Wambua J, Murungi LM, Osier FH, Biswas S, McCarthy JS, Minassian AM, Ashfield R, Viebig NK, Nugent FL, Douglas AD, Vekemans J, Wright GJ, Faust SN, Hill AV, Long CA, Lawrie AM, Draper SJ.

JCI Insight. 2017 Nov 2;2(21). pii: 96381. doi: 10.1172/jci.insight.96381.

34.

Functional characterization and comparison of Plasmodium falciparum proteins as targets of transmission-blocking antibodies.

Nikolaeva D, Illingworth JJ, Miura K, Alanine DG, Brian IJ, Li Y, Fyfe AJ, Da DF, Cohuet A, Long CA, Draper SJ, Biswas S.

Mol Cell Proteomics. 2017 Oct 31. pii: mcp.RA117.000036. doi: 10.1074/mcp.RA117.000036. [Epub ahead of print]

35.

Polyethylene Glycol Based Changes to β-Sheet Protein Conformational and Proteolytic Stability Depend on Conjugation Strategy and Location.

Draper SRE, Lawrence PB, Billings WM, Xiao Q, Brown NP, Bécar NA, Matheson DJ, Stephens AR, Price JL.

Bioconjug Chem. 2017 Oct 18;28(10):2507-2513. doi: 10.1021/acs.bioconjchem.7b00281. Epub 2017 Oct 9.

36.

Role of Activins in Hepcidin Regulation during Malaria.

Spottiswoode N, Armitage AE, Williams AR, Fyfe AJ, Biswas S, Hodgson SH, Llewellyn D, Choudhary P, Draper SJ, Duffy PE, Drakesmith H.

Infect Immun. 2017 Nov 17;85(12). pii: e00191-17. doi: 10.1128/IAI.00191-17. Print 2017 Dec.

37.

Hepcidin is regulated by promoter-associated histone acetylation and HDAC3.

Pasricha SR, Lim PJ, Duarte TL, Casu C, Oosterhuis D, Mleczko-Sanecka K, Suciu M, Da Silva AR, Al-Hourani K, Arezes J, McHugh K, Gooding S, Frost JN, Wray K, Santos A, Porto G, Repapi E, Gray N, Draper SJ, Ashley N, Soilleux E, Olinga P, Muckenthaler MU, Hughes JR, Rivella S, Milne TA, Armitage AE, Drakesmith H.

Nat Commun. 2017 Sep 1;8(1):403. doi: 10.1038/s41467-017-00500-z.

38.

Plasmodium falciparum malaria parasite var gene expression is modified by host antibodies: longitudinal evidence from controlled infections of Kenyan adults with varying natural exposure.

Abdi AI, Hodgson SH, Muthui MK, Kivisi CA, Kamuyu G, Kimani D, Hoffman SL, Juma E, Ogutu B, Draper SJ, Osier F, Bejon P, Marsh K, Bull PC.

BMC Infect Dis. 2017 Aug 23;17(1):585. doi: 10.1186/s12879-017-2686-0.

39.
40.

Normobaric Hypoxia and Submaximal Exercise Effects on Running Memory and Mood State in Women.

Seo Y, Gerhart HD, Stavres J, Fennell C, Draper S, Glickman EL.

Aerosp Med Hum Perform. 2017 Jul 1;88(7):627-632. doi: 10.3357/AMHP.4798.2017.

PMID:
28641679
41.

Human vaccination against Plasmodium vivax Duffy-binding protein induces strain-transcending antibodies.

Payne RO, Silk SE, Elias SC, Milne KH, Rawlinson TA, Llewellyn D, Shakri AR, Jin J, Labbé GM, Edwards NJ, Poulton ID, Roberts R, Farid R, Jørgensen T, Alanine DG, de Cassan SC, Higgins MK, Otto TD, McCarthy JS, de Jongh WA, Nicosia A, Moyle S, Hill AV, Berrie E, Chitnis CE, Lawrie AM, Draper SJ.

JCI Insight. 2017 Jun 15;2(12). pii: 93683. doi: 10.1172/jci.insight.93683. eCollection 2017 Jun 15.

42.

Flow through a very porous obstacle in a shallow channel.

Creed MJ, Draper S, Nishino T, Borthwick AGL.

Proc Math Phys Eng Sci. 2017 Apr;473(2200):20160672. doi: 10.1098/rspa.2016.0672. Epub 2017 Apr 26.

43.

Maximal Oxygen Uptake Is Achieved in Hypoxia but Not Normoxia during an Exhaustive Severe Intensity Run.

Black MI, Potter CR, Corbett J, Clark CC, Draper SB.

Front Physiol. 2017 Feb 21;8:96. doi: 10.3389/fphys.2017.00096. eCollection 2017.

44.

Accelerating the clinical development of protein-based vaccines for malaria by efficient purification using a four amino acid C-terminal 'C-tag'.

Jin J, Hjerrild KA, Silk SE, Brown RE, Labbé GM, Marshall JM, Wright KE, Bezemer S, Clemmensen SB, Biswas S, Li Y, El-Turabi A, Douglas AD, Hermans P, Detmers FJ, de Jongh WA, Higgins MK, Ashfield R, Draper SJ.

Int J Parasitol. 2017 Jun;47(7):435-446. doi: 10.1016/j.ijpara.2016.12.001. Epub 2017 Jan 30.

45.

One-step design of a stable variant of the malaria invasion protein RH5 for use as a vaccine immunogen.

Campeotto I, Goldenzweig A, Davey J, Barfod L, Marshall JM, Silk SE, Wright KE, Draper SJ, Higgins MK, Fleishman SJ.

Proc Natl Acad Sci U S A. 2017 Jan 31;114(5):998-1002. doi: 10.1073/pnas.1616903114. Epub 2017 Jan 17.

46.

Plasmodium vivax Controlled Human Malaria Infection - Progress and Prospects.

Payne RO, Griffin PM, McCarthy JS, Draper SJ.

Trends Parasitol. 2017 Feb;33(2):141-150. doi: 10.1016/j.pt.2016.11.001. Epub 2016 Dec 10. Review.

47.

Changes in Serological Immunology Measures in UK and Kenyan Adults Post-controlled Human Malaria Infection.

Hodgson SH, Llewellyn D, Silk SE, Milne KH, Elias SC, Miura K, Kamuyu G, Juma EA, Magiri C, Muia A, Jin J, Spencer AJ, Longley RJ, Mercier T, Decosterd L, Long CA, Osier FH, Hoffman SL, Ogutu B, Hill AV, Marsh K, Draper SJ.

Front Microbiol. 2016 Oct 13;7:1604. eCollection 2016.

48.

Iridium(III) Complexes Bearing Pyrene-Functionalized 1,10-Phenanthroline Ligands as Highly Efficient Sensitizers for Triplet-Triplet Annihilation Upconversion.

Lu Y, Wang J, McGoldrick N, Cui X, Zhao J, Caverly C, Twamley B, Ó Máille GM, Irwin B, Conway-Kenny R, Draper SM.

Angew Chem Int Ed Engl. 2016 Nov 14;55(47):14688-14692. doi: 10.1002/anie.201608442. Epub 2016 Oct 20.

PMID:
27762059
49.

Sonogashira Cross-Coupling as a Route to Tunable Hybrid Organic-Inorganic Rods with a Polyoxometalate Backbone.

Wang LS, Lu Y, Máille GM, Anthony SP, Nolan D, Draper SM.

Inorg Chem. 2016 Oct 3;55(19):9497-9500. Epub 2016 Sep 14.

PMID:
27627649
50.

Production of full-length soluble Plasmodium falciparum RH5 protein vaccine using a Drosophila melanogaster Schneider 2 stable cell line system.

Hjerrild KA, Jin J, Wright KE, Brown RE, Marshall JM, Labbé GM, Silk SE, Cherry CJ, Clemmensen SB, Jørgensen T, Illingworth JJ, Alanine DG, Milne KH, Ashfield R, de Jongh WA, Douglas AD, Higgins MK, Draper SJ.

Sci Rep. 2016 Jul 26;6:30357. doi: 10.1038/srep30357.

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