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Items: 20


Inhibition of natriuretic peptide receptor 1 reduces itch in mice.

Solinski HJ, Dranchak P, Oliphant E, Gu X, Earnest TW, Braisted J, Inglese J, Hoon MA.

Sci Transl Med. 2019 Jul 10;11(500). pii: eaav5464. doi: 10.1126/scitranslmed.aav5464.


Quantitative high-throughput screening assays for the discovery and development of SIRPĪ±-CD47 interaction inhibitors.

Miller TW, Amason JD, Garcin ED, Lamy L, Dranchak PK, Macarthur R, Braisted J, Rubin JS, Burgess TL, Farrell CL, Roberts DD, Inglese J.

PLoS One. 2019 Jul 5;14(7):e0218897. doi: 10.1371/journal.pone.0218897. eCollection 2019.


A fission yeast platform for heterologous expression of mammalian adenylyl cyclases and high throughput screening.

Getz RA, Kwak G, Cornell S, Mbugua S, Eberhard J, Huang SX, Abbasi Z, de Medeiros AS, Thomas R, Bukowski B, Dranchak PK, Inglese J, Hoffman CS.

Cell Signal. 2019 Aug;60:114-121. doi: 10.1016/j.cellsig.2019.04.010. Epub 2019 Apr 24.


Genome-Edited Cell Lines for High-Throughput Screening.

Dranchak P, Moran JJ, MacArthur R, Lopez-Anido C, Inglese J, Svaren J.

Methods Mol Biol. 2018;1755:1-17. doi: 10.1007/978-1-4939-7724-6_1.


Macrocycle peptides delineate locked-open inhibition mechanism for microorganism phosphoglycerate mutases.

Yu H, Dranchak P, Li Z, MacArthur R, Munson MS, Mehzabeen N, Baird NJ, Battalie KP, Ross D, Lovell S, Carlow CK, Suga H, Inglese J.

Nat Commun. 2017 Apr 3;8:14932. doi: 10.1038/ncomms14932.


Actinoramide A Identified as a Potent Antimalarial from Titration-Based Screening of Marine Natural Product Extracts.

Cheng KC, Cao S, Raveh A, MacArthur R, Dranchak P, Chlipala G, Okoneski MT, Guha R, Eastman RT, Yuan J, Schultz PJ, Su XZ, Tamayo-Castillo G, Matainaho T, Clardy J, Sherman DH, Inglese J.

J Nat Prod. 2015 Oct 23;78(10):2411-22. doi: 10.1021/acs.jnatprod.5b00489. Epub 2015 Oct 14.


Engineering bacterial transcription regulation to create a synthetic in vitro two-hybrid system for protein interaction assays.

Zhou Y, Asahara H, Schneider N, Dranchak P, Inglese J, Chong S.

J Am Chem Soc. 2014 Oct 8;136(40):14031-8. doi: 10.1021/ja502512g. Epub 2014 Sep 26.


Genome editing-enabled HTS assays expand drug target pathways for Charcot-Marie-tooth disease.

Inglese J, Dranchak P, Moran JJ, Jang SW, Srinivasan R, Santiago Y, Zhang L, Guha R, Martinez N, MacArthur R, Cost GJ, Svaren J.

ACS Chem Biol. 2014 Nov 21;9(11):2594-602. doi: 10.1021/cb5005492. Epub 2014 Sep 16.


Profile of the GSK published protein kinase inhibitor set across ATP-dependent and-independent luciferases: implications for reporter-gene assays.

Dranchak P, MacArthur R, Guha R, Zuercher WJ, Drewry DH, Auld DS, Inglese J.

PLoS One. 2013;8(3):e57888. doi: 10.1371/journal.pone.0057888. Epub 2013 Mar 7.


Diverse captive non-human primates with phytanic acid-deficient diets rich in plant products have substantial phytanic acid levels in their red blood cells.

Moser AB, Hey J, Dranchak PK, Karaman MW, Zhao J, Cox LA, Ryder OA, Hacia JG.

Lipids Health Dis. 2013 Feb 4;12:10. doi: 10.1186/1476-511X-12-10.


The gene expression profiles of induced pluripotent stem cells from individuals with childhood cerebral adrenoleukodystrophy are consistent with proposed mechanisms of pathogenesis.

Wang XM, Yik WY, Zhang P, Lu W, Dranchak PK, Shibata D, Steinberg SJ, Hacia JG.

Stem Cell Res Ther. 2012 Oct 4;3(5):39. doi: 10.1186/scrt130.


Nonsense suppressor therapies rescue peroxisome lipid metabolism and assembly in cells from patients with specific PEX gene mutations.

Dranchak PK, Di Pietro E, Snowden A, Oesch N, Braverman NE, Steinberg SJ, Hacia JG.

J Cell Biochem. 2011 May;112(5):1250-8. doi: 10.1002/jcb.22979.


mtDNA depletion confers specific gene expression profiles in human cells grown in culture and in xenograft.

Magda D, Lecane P, Prescott J, Thiemann P, Ma X, Dranchak PK, Toleno DM, Ramaswamy K, Siegmund KD, Hacia JG.

BMC Genomics. 2008 Nov 3;9:521. doi: 10.1186/1471-2164-9-521.


Synthesis and anticancer properties of water-soluble zinc ionophores.

Magda D, Lecane P, Wang Z, Hu W, Thiemann P, Ma X, Dranchak PK, Wang X, Lynch V, Wei W, Csokai V, Hacia JG, Sessler JL.

Cancer Res. 2008 Jul 1;68(13):5318-25. doi: 10.1158/0008-5472.CAN-08-0601.


Biochemical and genetic evaluation of the role of AMP-activated protein kinase in polysaccharide storage myopathy in Quarter Horses.

Dranchak PK, Leiper FC, Valberg SJ, Piercy RJ, Carling D, McCue ME, Mickelson JR.

Am J Vet Res. 2007 Oct;68(10):1079-84.


Exclusion of linkage of the RYR1, CACNA1S, and ATP2A1 genes to recurrent exertional rhabdomyolysis in Thoroughbreds.

Dranchak PK, Valberg SJ, Onan GW, Gallant EM, Binns MM, Swinburne JE, Mickelson JR.

Am J Vet Res. 2006 Aug;67(8):1395-400.


Chromosomal assignments for the equine AMPK family genes.

Dranchak PK, Ekenstedt KJ, Valberg SJ, Chowdhary BP, Raudsepp T, Mickelson JR.

Anim Genet. 2006 Jun;37(3):293-4. No abstract available.


A 1.3-Mb interval map of equine homologs of HSA2.

Wagner ML, Raudsepp T, Goh G, Agarwala R, Schaffer AA, Dranchak PK, Brinkmeyer-Langford C, Skow LC, Chowdhary BP, Mickelson JR.

Cytogenet Genome Res. 2006;112(3-4):227-34.


Inheritance of recurrent exertional rhabdomyolysis in thoroughbreds.

Dranchak PK, Valberg SJ, Onan GW, Gallant EM, MacLeay JM, McKenzie EC, De La Corte FD, Ekenstedt K, Mickelson JR.

J Am Vet Med Assoc. 2005 Sep 1;227(5):762-7.


Turkey microsatellite loci from an embryonic cDNA library.

Dranchak PK, Chaves LD, Rowe JA, Reed KM.

Poult Sci. 2003 Apr;82(4):526-31.

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