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Items: 1 to 50 of 114

1.

Confounders of mutation-rate estimators: selection and phenotypic lag in Thermus thermophilus.

Kissling GE, Grogan DW, Drake JW.

Mutat Res. 2013 Sep;749(1-2):16-20. doi: 10.1016/j.mrfmmm.2013.07.006. Epub 2013 Aug 2. Review.

2.

Experimental selection reveals a trade-off between fecundity and lifespan in the coliphage Qß.

García-Villada L, Drake JW.

Open Biol. 2013 Jun 12;3(6):130043. doi: 10.1098/rsob.130043.

3.

The three faces of riboviral spontaneous mutation: spectrum, mode of genome replication, and mutation rate.

García-Villada L, Drake JW.

PLoS Genet. 2012;8(7):e1002832. doi: 10.1371/journal.pgen.1002832. Epub 2012 Jul 26.

4.

Contrasting mutation rates from specific-locus and long-term mutation-accumulation procedures.

Drake JW.

G3 (Bethesda). 2012 Apr;2(4):483-5. doi: 10.1534/g3.111.001842. Epub 2012 Apr 1.

5.

The bacteriophage T4 rapid-lysis genes and their mutational proclivities.

Burch LH, Zhang L, Chao FG, Xu H, Drake JW.

J Bacteriol. 2011 Jul;193(14):3537-45. doi: 10.1128/JB.00138-11. Epub 2011 May 13.

6.

Reversal of a mutator activity by a nearby fidelity-neutral substitution in the RB69 DNA polymerase binding pocket.

Trzemecka A, Jacewicz A, Carver GT, Drake JW, Bebenek A.

J Mol Biol. 2010 Dec 17;404(5):778-93. doi: 10.1016/j.jmb.2010.09.058. Epub 2010 Oct 13.

7.

Mutational clusters generated by non-processive polymerases: A case study using DNA polymerase betain vitro.

García-Villada L, Drake JW.

DNA Repair (Amst). 2010 Aug 5;9(8):871-8. doi: 10.1016/j.dnarep.2010.05.002. Epub 2010 Jun 2.

8.

Avoiding dangerous missense: thermophiles display especially low mutation rates.

Drake JW.

PLoS Genet. 2009 Jun;5(6):e1000520. doi: 10.1371/journal.pgen.1000520. Epub 2009 Jun 19.

9.

Intensive therapy of type 2 diabetes (ACCORD trial) (OCTOBER 2008).

Drake JW.

Cleve Clin J Med. 2009 Feb;76(2):83; author reply 83-4. doi: 10.3949/ccjm.76c.01002. No abstract available.

PMID:
19188471
10.

The rate and character of spontaneous mutation in Thermus thermophilus.

Mackwan RR, Carver GT, Kissling GE, Drake JW, Grogan DW.

Genetics. 2008 Sep;180(1):17-25. doi: 10.1534/genetics.108.089086. Epub 2008 Aug 24.

11.

Templated mutagenesis in bacteriophage T4 involving imperfect direct or indirect sequence repeats.

Schultz GE Jr, Drake JW.

Genetics. 2008 Feb;178(2):661-73. doi: 10.1534/genetics.107.083444. Epub 2008 Feb 1.

12.

Too many mutants with multiple mutations.

Drake JW.

Crit Rev Biochem Mol Biol. 2007 Jul-Aug;42(4):247-58. Review.

13.

Mutations in clusters and showers.

Drake JW.

Proc Natl Acad Sci U S A. 2007 May 15;104(20):8203-4. Epub 2007 May 10. No abstract available.

14.

The roles of Tyr391 and Tyr619 in RB69 DNA polymerase replication fidelity.

Jacewicz A, Makiela K, Kierzek A, Drake JW, Bebenek A.

J Mol Biol. 2007 Apr 20;368(1):18-29. Epub 2007 Feb 3.

15.

An unusual pattern of spontaneous mutations recovered in the halophilic archaeon Haloferax volcanii.

Mackwan RR, Carver GT, Drake JW, Grogan DW.

Genetics. 2007 May;176(1):697-702. Epub 2006 Dec 28.

16.

Chaos and order in spontaneous mutation.

Drake JW.

Genetics. 2006 May;173(1):1-8. No abstract available.

17.

A role for replication repair in the genesis of templated mutations.

Schultz GE Jr, Carver GT, Drake JW.

J Mol Biol. 2006 May 12;358(4):963-73. Epub 2006 Mar 30.

PMID:
16574154
18.

The L561A substitution in the nascent base-pair binding pocket of RB69 DNA polymerase reduces base discrimination.

Zhang H, Rhee C, Bebenek A, Drake JW, Wang J, Konigsberg W.

Biochemistry. 2006 Feb 21;45(7):2211-20.

19.

Clusters of mutations from transient hypermutability.

Drake JW, Bebenek A, Kissling GE, Peddada S.

Proc Natl Acad Sci U S A. 2005 Sep 6;102(36):12849-54. Epub 2005 Aug 23.

20.

On the mutation rate of herpes simplex virus type 1.

Drake JW, Hwang CB.

Genetics. 2005 Jun;170(2):969-70. Epub 2005 Mar 31.

22.

Anecdotal, historical and critical commentaries on genetics. Gisela Mosig.

Nossal NG, Franklin JL, Kutter E, Drake JW.

Genetics. 2004 Nov;168(3):1097-104. No abstract available.

24.

UvsX recombinase and Dda helicase rescue stalled bacteriophage T4 DNA replication forks in vitro.

Kadyrov FA, Drake JW.

J Biol Chem. 2004 Aug 20;279(34):35735-40. Epub 2004 Jun 11.

25.

Properties of bacteriophage T4 proteins deficient in replication repair.

Kadyrov FA, Drake JW.

J Biol Chem. 2003 Jul 4;278(27):25247-55. Epub 2003 Apr 14.

26.

The rate and character of spontaneous mutation in an RNA virus.

Malpica JM, Fraile A, Moreno I, Obies CI, Drake JW, García-Arenal F.

Genetics. 2002 Dec;162(4):1505-11.

27.

Dissecting the fidelity of bacteriophage RB69 DNA polymerase: site-specific modulation of fidelity by polymerase accessory proteins.

Bebenek A, Carver GT, Dressman HK, Kadyrov FA, Haseman JK, Petrov V, Konigsberg WH, Karam JD, Drake JW.

Genetics. 2002 Nov;162(3):1003-18.

29.

Genetic fidelity under harsh conditions: analysis of spontaneous mutation in the thermoacidophilic archaeon Sulfolobus acidocaldarius.

Grogan DW, Carver GT, Drake JW.

Proc Natl Acad Sci U S A. 2001 Jul 3;98(14):7928-33. Epub 2001 Jun 26.

30.

Conditional coupling of leading-strand and lagging-strand DNA synthesis at bacteriophage T4 replication forks.

Kadyrov FA, Drake JW.

J Biol Chem. 2001 Aug 3;276(31):29559-66. Epub 2001 Jun 4.

31.

Interacting fidelity defects in the replicative DNA polymerase of bacteriophage RB69.

Bebenek A, Dressman HK, Carver GT, Ng S, Petrov V, Yang G, Konigsberg WH, Karam JD, Drake JW.

J Biol Chem. 2001 Mar 30;276(13):10387-97. Epub 2000 Dec 22.

32.

Mutation rates among RNA viruses.

Drake JW, Holland JJ.

Proc Natl Acad Sci U S A. 1999 Nov 23;96(24):13910-3.

33.

The distribution of rates of spontaneous mutation over viruses, prokaryotes, and eukaryotes.

Drake JW.

Ann N Y Acad Sci. 1999 May 18;870:100-7. Review.

PMID:
10415476
34.
35.
36.

Rates of spontaneous mutation.

Drake JW, Charlesworth B, Charlesworth D, Crow JF.

Genetics. 1998 Apr;148(4):1667-86. Review.

37.
38.

Retention of replication fidelity by a DNA polymerase functioning in a distantly related environment.

Dressman HK, Wang CC, Karam JD, Drake JW.

Proc Natl Acad Sci U S A. 1997 Jul 22;94(15):8042-6.

39.

The 1996 Thomas Hunt Morgan Medal Franklin W. Stahl.

Drake JW.

Genetics. 1997 Jan;145(1):1-2. No abstract available.

40.

Recollections of Howard Temin (1934-1994).

Drake JW, Crow JF.

Genetics. 1996 Sep;144(1):1-6. No abstract available.

41.
42.

The 1995 Thomas Hunt Morgan Medal. Matthew Meselson.

Drake JW.

Genetics. 1996 Jan;142(1):1-2. No abstract available.

43.
44.

Looking backward on a century of mutation research.

Drake JW.

Environ Mol Mutagen. 1994;23 Suppl 24:11-4.

PMID:
8162900
45.

Rates of spontaneous mutation among RNA viruses.

Drake JW.

Proc Natl Acad Sci U S A. 1993 May 1;90(9):4171-5.

46.

General antimutators are improbable.

Drake JW.

J Mol Biol. 1993 Jan 5;229(1):8-13.

PMID:
8421317
47.

Duplication-targeted DNA methylation and mutagenesis in the evolution of eukaryotic chromosomes.

Kricker MC, Drake JW, Radman M.

Proc Natl Acad Sci U S A. 1992 Feb 1;89(3):1075-9.

48.

Mutation rates.

Drake JW.

Bioessays. 1992 Feb;14(2):137-40. Review. No abstract available.

PMID:
1575714
49.

Ernst Freese (1925-1990).

Drake JW.

Mutat Res. 1991 Dec;251(2):165-9. No abstract available.

PMID:
1720866
50.

A constant rate of spontaneous mutation in DNA-based microbes.

Drake JW.

Proc Natl Acad Sci U S A. 1991 Aug 15;88(16):7160-4.

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