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Hyperarousal and sleep reactivity in insomnia: current insights.

Kalmbach DA, Cuamatzi-Castelan AS, Tonnu CV, Tran KM, Anderson JR, Roth T, Drake CL.

Nat Sci Sleep. 2018 Jul 17;10:193-201. doi: 10.2147/NSS.S138823. eCollection 2018. Review.


Absence of host NF-κB p50 induces murine glioblastoma tumor regression, increases survival, and decreases T-cell induction of tumor-associated macrophage M2 polarization.

Barberi T, Martin A, Suresh R, Barakat DJ, Harris-Bookman S, Drake CG, Lim M, Friedman AD.

Cancer Immunol Immunother. 2018 Jul 21. doi: 10.1007/s00262-018-2184-2. [Epub ahead of print]


Psychological Impact of Shift Work.

Cheng P, Drake CL.

Curr Sleep Med Rep. 2018 Jun;4(2):104-109. Epub 2018 Apr 12.


Ipilimumab plus nivolumab and DNA-repair defects in AR-V7-expressing metastatic prostate cancer.

Boudadi K, Suzman DL, Anagnostou V, Fu W, Luber B, Wang H, Niknafs N, White JR, Silberstein JL, Sullivan R, Dowling D, Harb R, Nirschl TR, Veeneman BA, Tomlins SA, Wang Y, Jendrisak A, Graf RP, Dittamore R, Carducci MA, Eisenberger MA, Haffner MC, Meeker AK, Eshleman JR, Luo J, Velculescu VE, Drake CG, Antonarakis ES.

Oncotarget. 2018 Jun 19;9(47):28561-28571. doi: 10.18632/oncotarget.25564. eCollection 2018 Jun 19.


IKZF1 Enhances Immune Infiltrate Recruitment in Solid Tumors and Susceptibility to Immunotherapy.

Chen JC, Perez-Lorenzo R, Saenger YM, Drake CG, Christiano AM.

Cell Syst. 2018 Jul 25;7(1):92-103.e4. doi: 10.1016/j.cels.2018.05.020. Epub 2018 Jun 27.


Systemic depletion of lymphocytes following focal radiation to the brain in a murine model.

Piotrowski AF, Nirschl TR, Velarde E, Blosser L, Ganguly S, Burns KH, Luznik L, Wong J, Drake CG, Grossman SA.

Oncoimmunology. 2018 May 9;7(7):e1445951. doi: 10.1080/2162402X.2018.1445951. eCollection 2018.


Elective nodal irradiation attenuates the combinatorial efficacy of stereotactic radiation therapy and immunotherapy.

Marciscano AE, Ghasemzadeh A, Nirschl TR, Theodros D, Kochel CM, Francica BJ, Muroyama Y, Anders RA, Sharabi AB, Velarde E, Mao W, Chaudhary KR, Chaimowitz MG, Wong J, Selby M, Thudium KB, Korman AJ, Ulmert D, Thorek DL, DeWeese TL, Drake CG.

Clin Cancer Res. 2018 Jun 13. pii: clincanres.3427.2017. doi: 10.1158/1078-0432.CCR-17-3427. [Epub ahead of print]


Antigen-Specific CD8 Lytic Phenotype Induced by Sipuleucel-T in Hormone-Sensitive or Castration-Resistant Prostate Cancer and Association with Overall Survival.

Antonarakis ES, Small EJ, Petrylak DP, Quinn DI, Kibel AS, Chang NN, Dearstyne E, Harmon M, Campogan D, Haynes H, Vu T, Sheikh NA, Drake CG.

Clin Cancer Res. 2018 Jun 1. doi: 10.1158/1078-0432.CCR-18-0638. [Epub ahead of print]


The impact of stress on sleep: Pathogenic sleep reactivity as a vulnerability to insomnia and circadian disorders.

Kalmbach DA, Anderson JR, Drake CL.

J Sleep Res. 2018 May 24:e12710. doi: 10.1111/jsr.12710. [Epub ahead of print] Review.


Efficacy of digital CBT for insomnia to reduce depression across demographic groups: a randomized trial.

Cheng P, Luik AI, Fellman-Couture C, Peterson E, Joseph CLM, Tallent G, Tran KM, Ahmedani BK, Roehrs T, Roth T, Drake CL.

Psychol Med. 2018 May 24:1-10. doi: 10.1017/S0033291718001113. [Epub ahead of print]


Psychosocial variables and presence, severity and prognosis of plantar heel pain: A systematic review of cross-sectional and prognostic associations.

Drake C, Mallows A, Littlewood C.

Musculoskeletal Care. 2018 May 15. doi: 10.1002/msc.1246. [Epub ahead of print]


Lack of Resilience Is Related to Stress-Related Sleep Reactivity, Hyperarousal, and Emotion Dysregulation in Insomnia Disorder.

Palagini L, Moretto U, Novi M, Masci I, Caruso D, Drake CL, Riemann D.

J Clin Sleep Med. 2018 May 15;14(5):759-766. doi: 10.5664/jcsm.7100.


PD-L1 expression in medulloblastoma: an evaluation by subgroup.

Martin AM, Nirschl CJ, Polanczyk MJ, Bell WR, Nirschl TR, Harris-Bookman S, Phallen J, Hicks J, Martinez D, Ogurtsova A, Xu H, Sullivan LM, Meeker AK, Raabe EH, Cohen KJ, Eberhart CG, Burger PC, Santi M, Taube JM, Pardoll DM, Drake CG, Lim M.

Oncotarget. 2018 Apr 10;9(27):19177-19191. doi: 10.18632/oncotarget.24951. eCollection 2018 Apr 10.


Factor structure of the Brazilian version of Pediatric Daytime Sleepiness Scale.

Ferrari Junior GJ, Drake CL, Barbosa DG, Diego Andrade R, Santos Silva DA, Érico Pereira GF.

Chronobiol Int. 2018 Apr 24:1-7. doi: 10.1080/07420528.2018.1458732. [Epub ahead of print]


Carbon-13 Cross-Polarization Magic-Angle Spinning Nuclear Magnetic Resonance for Measuring Proanthocyanidin Content and Procyanidin to Prodelphinidin Ratio in Sainfoin ( Onobrychis viciifolia) Tissues.

Fryganas C, Drake C, Ropiak HM, Mora-Ortiz M, Smith LMJ, Mueller-Harvey I, Kowalczyk RM.

J Agric Food Chem. 2018 Apr 25;66(16):4073-4081. doi: 10.1021/acs.jafc.8b01215. Epub 2018 Apr 13.


Comprehensive Evaluation of Programmed Death-Ligand 1 Expression in Primary and Metastatic Prostate Cancer.

Haffner MC, Guner G, Taheri D, Netto GJ, Palsgrove DN, Zheng Q, Guedes LB, Kim K, Tsai H, Esopi DM, Lotan TL, Sharma R, Meeker AK, Chinnaiyan AM, Nelson WG, Yegnasubramanian S, Luo J, Mehra R, Antonarakis ES, Drake CG, De Marzo AM.

Am J Pathol. 2018 Jun;188(6):1478-1485. doi: 10.1016/j.ajpath.2018.02.014. Epub 2018 Mar 22.


Insomnia and hypertension: A systematic review.

Jarrin DC, Alvaro PK, Bouchard MA, Jarrin SD, Drake CL, Morin CM.

Sleep Med Rev. 2018 Feb 16. pii: S1087-0792(17)30051-5. doi: 10.1016/j.smrv.2018.02.003. [Epub ahead of print] Review.


An Obesity Risk Assessment Tool for Young Children: Validity With BMI and Nutrient Values.

Townsend MS, Shilts MK, Styne DM, Drake C, Lanoue L, Ontai L.

J Nutr Educ Behav. 2018 Jul - Aug;50(7):705-717. doi: 10.1016/j.jneb.2018.01.022. Epub 2018 Mar 19.


Combining immune check-point blockade and cryoablation in an immunocompetent hormone sensitive murine model of prostate cancer.

Benzon B, Glavaris SA, Simons BW, Hughes RM, Ghabili K, Mullane P, Miller R, Nugent K, Shinder B, Tosoian J, Fuchs EJ, Tran PT, Hurley PJ, Vuica-Ross M, Schaeffer EM, Drake CG, Ross AE.

Prostate Cancer Prostatic Dis. 2018 Apr;21(1):126-136. doi: 10.1038/s41391-018-0035-z. Epub 2018 Mar 20.


Medical Costs of Fatal and Nonfatal Falls in Older Adults.

Florence CS, Bergen G, Atherly A, Burns E, Stevens J, Drake C.

J Am Geriatr Soc. 2018 Apr;66(4):693-698. doi: 10.1111/jgs.15304. Epub 2018 Mar 7.


Daytime Sleep Disturbance in Night Shift Work and the Role of PERIOD3.

Cheng P, Tallent G, Burgess HJ, Tran KM, Roth T, Drake CL.

J Clin Sleep Med. 2018 Mar 15;14(3):393-400. doi: 10.5664/jcsm.6984.


Characterization of Condensed Tannins from Purple Prairie Clover (Dalea purpurea Vent.) Conserved as either Freeze-Dried Forage, Sun-Cured Hay or Silage.

Peng K, Huang Q, Xu Z, McAllister TA, Acharya S, Mueller-Harvey I, Drake C, Cao J, Huang Y, Sun Y, Wang S, Wang Y.

Molecules. 2018 Mar 6;23(3). pii: E586. doi: 10.3390/molecules23030586.


Finished Genome Sequence of a Polyurethane-Degrading Pseudomonas Isolate.

Stamps BW, Zingarelli S, Hung CS, Drake CA, Varaljay VA, Stevenson BS, Crookes-Goodson WJ.

Genome Announc. 2018 Mar 1;6(9). pii: e00084-18. doi: 10.1128/genomeA.00084-18.


TNFα and Radioresistant Stromal Cells Are Essential for Therapeutic Efficacy of Cyclic Dinucleotide STING Agonists in Nonimmunogenic Tumors.

Francica BJ, Ghasemzadeh A, Desbien AL, Theodros D, Sivick KE, Reiner GL, Hix Glickman L, Marciscano AE, Sharabi AB, Leong ML, McWhirter SM, Dubensky TW Jr, Pardoll DM, Drake CG.

Cancer Immunol Res. 2018 Apr;6(4):422-433. doi: 10.1158/2326-6066.CIR-17-0263. Epub 2018 Feb 22.


Quantitative Analysis of Immune Infiltrates in Primary Melanoma.

Gartrell RD, Marks DK, Hart TD, Li G, Davari DR, Wu A, Blake Z, Lu Y, Askin KN, Monod A, Esancy CL, Stack EC, Jia DT, Armenta PM, Fu Y, Izaki D, Taback B, Rabadan R, Kaufman HL, Drake CG, Horst BA, Saenger YM.

Cancer Immunol Res. 2018 Apr;6(4):481-493. doi: 10.1158/2326-6066.CIR-17-0360. Epub 2018 Feb 21.


Nocturnal insomnia symptoms and stress-induced cognitive intrusions in risk for depression: A 2-year prospective study.

Kalmbach DA, Pillai V, Drake CL.

PLoS One. 2018 Feb 13;13(2):e0192088. doi: 10.1371/journal.pone.0192088. eCollection 2018.


Condensed Tannin Changes along the Digestive Tract in Lambs Fed with Sainfoin Pellets or Hazelnut Skins.

Quijada J, Drake C, Gaudin E, El-Korso R, Hoste H, Mueller-Harvey I.

J Agric Food Chem. 2018 Mar 7;66(9):2136-2142. doi: 10.1021/acs.jafc.7b05538. Epub 2018 Feb 21.


Blocking PD-1/PD-L1 in Genitourinary Malignancies: To Immunity and Beyond.

Dallos MC, Drake CG.

Cancer J. 2018 Jan/Feb;24(1):20-30. doi: 10.1097/PPO.0000000000000302.


Anti-IL-10-mediated Enhancement of Antitumor Efficacy of a Dendritic Cell-targeting MIP3α-gp100 Vaccine in the B16F10 Mouse Melanoma Model Is Dependent on Type I Interferons.

Gordy JT, Luo K, Francica B, Drake C, Markham RB.

J Immunother. 2018 May;41(4):181-189. doi: 10.1097/CJI.0000000000000212.


Inhibitors of the PD-1 Pathway in Tumor Therapy.

LaFleur MW, Muroyama Y, Drake CG, Sharpe AH.

J Immunol. 2018 Jan 15;200(2):375-383. doi: 10.4049/jimmunol.1701044.


Genomic correlates of response to immune checkpoint therapies in clear cell renal cell carcinoma.

Miao D, Margolis CA, Gao W, Voss MH, Li W, Martini DJ, Norton C, Bossé D, Wankowicz SM, Cullen D, Horak C, Wind-Rotolo M, Tracy A, Giannakis M, Hodi FS, Drake CG, Ball MW, Allaf ME, Snyder A, Hellmann MD, Ho T, Motzer RJ, Signoretti S, Kaelin WG Jr, Choueiri TK, Van Allen EM.

Science. 2018 Feb 16;359(6377):801-806. doi: 10.1126/science.aan5951. Epub 2018 Jan 4.


Bipolar androgen therapy in men with metastatic castration-resistant prostate cancer after progression on enzalutamide: an open-label, phase 2, multicohort study.

Teply BA, Wang H, Luber B, Sullivan R, Rifkind I, Bruns A, Spitz A, DeCarli M, Sinibaldi V, Pratz CF, Lu C, Silberstein JL, Luo J, Schweizer MT, Drake CG, Carducci MA, Paller CJ, Antonarakis ES, Eisenberger MA, Denmeade SR.

Lancet Oncol. 2018 Jan;19(1):76-86. doi: 10.1016/S1470-2045(17)30906-3. Epub 2017 Dec 14.


Combining intratumoral Treg depletion with androgen deprivation therapy (ADT): preclinical activity in the Myc-CaP model.

Shen YC, Ghasemzadeh A, Kochel CM, Nirschl TR, Francica BJ, Lopez-Bujanda ZA, Carrera Haro MA, Tam A, Anders RA, Selby MJ, Korman AJ, Drake CG.

Prostate Cancer Prostatic Dis. 2018 Apr;21(1):113-125. doi: 10.1038/s41391-017-0013-x. Epub 2017 Dec 4.


Efficacy and safety of aripiprazole lauroxil once-monthly versus aripiprazole once-monthly long-acting injectable formulations in patients with acute symptoms of schizophrenia: an indirect comparison of two double-blind placebo-controlled studies.

Cameron C, Zummo J, Desai D, Drake C, Hutton B, Kotb A, Weiden PJ.

Curr Med Res Opin. 2018 Apr;34(4):725-733. doi: 10.1080/03007995.2017.1410471. Epub 2018 Jan 10.


Biomarkers for immunotherapy in bladder cancer: a moving target.

Aggen DH, Drake CG.

J Immunother Cancer. 2017 Nov 21;5(1):94. doi: 10.1186/s40425-017-0299-1. Review.


Muscadine Grape Skin Extract (MPX) in Men with Biochemically Recurrent Prostate Cancer: A Randomized, Multicenter, Placebo-Controlled Clinical Trial.

Paller CJ, Zhou XC, Heath EI, Taplin ME, Mayer T, Stein MN, Bubley GJ, Pili R, Hudson T, Kakarla R, Abbas MM, Anders NM, Dowling D, King S, Bruns AB, Wagner WD, Drake CG, Antonarakis ES, Eisenberger MA, Denmeade SR, Rudek MA, Rosner GL, Carducci MA.

Clin Cancer Res. 2018 Jan 15;24(2):306-315. doi: 10.1158/1078-0432.CCR-17-1100. Epub 2017 Nov 7.


Production of diverse PET probes with limited resources: 24 18F-labeled compounds prepared with a single radiosynthesizer.

Collins J, Waldmann CM, Drake C, Slavik R, Ha NS, Sergeev M, Lazari M, Shen B, Chin FT, Moore M, Sadeghi S, Phelps ME, Murphy JM, van Dam RM.

Proc Natl Acad Sci U S A. 2017 Oct 24;114(43):11309-11314. doi: 10.1073/pnas.1710466114. Epub 2017 Oct 10.


Prostate Cancer Cells Express More Androgen Receptor (AR) Following Androgen Deprivation, Improving Recognition by AR-Specific T Cells.

Olson BM, Gamat M, Seliski J, Sawicki T, Jeffery J, Ellis L, Drake CG, Weichert J, McNeel DG.

Cancer Immunol Res. 2017 Dec;5(12):1074-1085. doi: 10.1158/2326-6066.CIR-16-0390. Epub 2017 Oct 19.


Validation of the German version of the Ford Insomnia Response to Stress Test.

Dieck A, Helbig S, Drake CL, Backhaus J.

J Sleep Res. 2018 Jun;27(3):e12621. doi: 10.1111/jsr.12621. Epub 2017 Oct 19.


Outcomes Following Clinical Complete Response to Neoadjuvant Chemotherapy for Muscle-invasive Urothelial Carcinoma of the Bladder in Patients Refusing Radical Cystectomy.

Robins D, Matulay J, Lipsky M, Meyer A, Ghandour R, DeCastro G, Anderson C, Drake C, Benson M, McKiernan JM.

Urology. 2018 Jan;111:116-121. doi: 10.1016/j.urology.2017.09.003. Epub 2017 Oct 12.


Stereotactic Radiotherapy Increases Functionally Suppressive Regulatory T Cells in the Tumor Microenvironment.

Muroyama Y, Nirschl TR, Kochel CM, Lopez-Bujanda Z, Theodros D, Mao W, Carrera-Haro MA, Ghasemzadeh A, Marciscano AE, Velarde E, Tam AJ, Thoburn CJ, Uddin M, Meeker AK, Anders RA, Pardoll DM, Drake CG.

Cancer Immunol Res. 2017 Nov;5(11):992-1004. doi: 10.1158/2326-6066.CIR-17-0040. Epub 2017 Oct 2.


Familial Risk for Insomnia Is Associated With Abnormal Cortisol Response to Stress.

Drake CL, Cheng P, Almeida DM, Roth T.

Sleep. 2017 Oct 1;40(10). doi: 10.1093/sleep/zsx143.


Novel pathogenic mutations in C1QTNF5 support a dominant negative disease mechanism in late-onset retinal degeneration.

Stanton CM, Borooah S, Drake C, Marsh JA, Campbell S, Lennon A, Soares DC, Vallabh NA, Sahni J, Cideciyan AV, Dhillon B, Vitart V, Jacobson SG, Wright AF, Hayward C.

Sci Rep. 2017 Sep 22;7(1):12147. doi: 10.1038/s41598-017-11898-3.


Further studies on the iodine concentration of conventional, organic and UHT semi-skimmed milk at retail in the UK.

Stevenson MC, Drake C, Givens DI.

Food Chem. 2018 Jan 15;239:551-555. doi: 10.1016/j.foodchem.2017.06.135. Epub 2017 Jun 30.


Concomitant thyroid disease and primary hyperparathyroidism in patients undergoing parathyroidectomy or thyroidectomy.

Wright MC, Jensen K, Mohamed H, Drake C, Mohsin K, Monlezun D, Alsaleh N, Kandil E.

Gland Surg. 2017 Aug;6(4):368-374. doi: 10.21037/gs.2017.04.01.


Precision, complexity and stigma in advanced prostate cancer terminology: it is time to move away from 'castration-resistant' prostate cancer.

Pezaro CJ, Omlin A, Mastris K; ANZUP Consumer Advisory Panel, Attard G, Beer TM, Chi KN, Chowdhury S, Davis ID, Drake CG, de Bono JS, Efstathiou E, Gravis G, Higano CS, Hussain M, James N, Logothetis CJ, Morgans A, Parker C, Ryan CJ, Saad F, Sartor O, Small EJ, Sternberg CN, Sweeney CJ, Tannock I, Tombal B, Gillessen S.

Ann Oncol. 2017 Aug 1;28(8):1692-1694. doi: 10.1093/annonc/mdx312. No abstract available.


Cutaneous Eruptions in Patients Receiving Immune Checkpoint Blockade: Clinicopathologic Analysis of the Nonlichenoid Histologic Pattern.

Kaunitz GJ, Loss M, Rizvi H, Ravi S, Cuda JD, Bleich KB, Esandrio J, Sander I, Le DT, Diaz LA Jr, Brahmer JR, Drake CG, Hollmann TJ, Lacouture ME, Hellmann MD, Lipson EJ, Taube JM.

Am J Surg Pathol. 2017 Oct;41(10):1381-1389. doi: 10.1097/PAS.0000000000000900.


Facile Purification of Milligram to Gram Quantities of Condensed Tannins According to Mean Degree of Polymerization and Flavan-3-ol Subunit Composition.

Brown RH, Mueller-Harvey I, Zeller WE, Reinhardt L, Stringano E, Gea A, Drake C, Ropiak HM, Fryganas C, Ramsay A, Hardcastle EE.

J Agric Food Chem. 2017 Sep 13;65(36):8072-8082. doi: 10.1021/acs.jafc.7b03489. Epub 2017 Sep 1.


A Prospective Study of Chronic Inflammation in Benign Prostate Tissue and Risk of Prostate Cancer: Linked PCPT and SELECT Cohorts.

Platz EA, Kulac I, Barber JR, Drake CG, Joshu CE, Nelson WG, Lucia MS, Klein EA, Lippman SM, Parnes HL, Thompson IM, Goodman PJ, Tangen CM, De Marzo AM.

Cancer Epidemiol Biomarkers Prev. 2017 Oct;26(10):1549-1557. doi: 10.1158/1055-9965.EPI-17-0503. Epub 2017 Jul 28.


The Landscape of Whole-genome Alterations and Pathologic Features in Genitourinary Malignancies: An Analysis of the Cancer Genome Atlas.

Ball MW, Gorin MA, Drake CG, Hammers HJ, Allaf ME.

Eur Urol Focus. 2017 Dec;3(6):584-589. doi: 10.1016/j.euf.2017.01.007. Epub 2017 Feb 8.


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