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A new point-of-care test to diagnose tuberculosis.

Drain PK, Heichman KA, Wilson D.

Lancet Infect Dis. 2019 May 30. pii: S1473-3099(19)30053-2. doi: 10.1016/S1473-3099(19)30053-2. [Epub ahead of print] No abstract available.


Point-of-Care HIV Viral Load Testing: an Essential Tool for a Sustainable Global HIV/AIDS Response.

Drain PK, Dorward J, Bender A, Lillis L, Marinucci F, Sacks J, Bershteyn A, Boyle DS, Posner JD, Garrett N.

Clin Microbiol Rev. 2019 May 15;32(3). pii: e00097-18. doi: 10.1128/CMR.00097-18. Print 2019 Jun 19. Review.


Development and Validation of an Immunoassay for Tenofovir in Urine as a Real-Time Metric of Antiretroviral Adherence.

Gandhi M, Bacchetti P, Rodrigues WC, Spinelli M, Koss CA, Drain PK, Baeten JM, Mugo NR, Ngure K, Benet LZ, Okochi H, Wang G, Vincent M.

EClinicalMedicine. 2018 Aug-Sep;2-3:22-28. doi: 10.1016/j.eclinm.2018.08.004. Epub 2018 Aug 31.


Poor supply chain management and stock-outs of point-of-care diagnostic tests in Upper East Region's primary healthcare clinics, Ghana.

Kuupiel D, Tlou B, Bawontuo V, Drain PK, Mashamba-Thompson TP.

PLoS One. 2019 Feb 27;14(2):e0211498. doi: 10.1371/journal.pone.0211498. eCollection 2019.


Validation of clinic-based cryptococcal antigen lateral flow assay screening in HIV-infected adults in South Africa.

Drain PK, Hong T, Krows M, Govere S, Thulare H, Wallis CL, Gosnell BI, Moosa MY, Bassett IV, Celum C.

Sci Rep. 2019 Feb 25;9(1):2687. doi: 10.1038/s41598-018-37478-7.


Integrating hypertension screening at the time of voluntary HIV testing among adults in South Africa.

Drain PK, Hong T, Hajat A, Krows M, Govere S, Thulare H, Moosa MYS, Bassett I, Celum C.

PLoS One. 2019 Feb 8;14(2):e0210161. doi: 10.1371/journal.pone.0210161. eCollection 2019.


Brief Report: Validation of a Urine Tenofovir Immunoassay for Adherence Monitoring to PrEP and ART and Establishing the Cutoff for a Point-of-Care Test.

Gandhi M, Bacchetti P, Spinelli MA, Okochi H, Baeten JM, Siriprakaisil O, Klinbuayaem V, Rodrigues WC, Wang G, Vincent M, Cressey TR, Drain PK.

J Acquir Immune Defic Syndr. 2019 May 1;81(1):72-77. doi: 10.1097/QAI.0000000000001971.


Associations Between Anxiety and Adherence to Antiretroviral Medications in Low- and Middle-Income Countries: A Systematic Review and Meta-analysis.

Wykowski J, Kemp CG, Velloza J, Rao D, Drain PK.

AIDS Behav. 2019 Jan 18. doi: 10.1007/s10461-018-02390-8. [Epub ahead of print] Review.


Subclinical tuberculosis among adults with HIV: clinical features and outcomes in a South African cohort.

Bajema KL, Bassett IV, Coleman SM, Ross D, Freedberg KA, Wald A, Drain PK.

BMC Infect Dis. 2019 Jan 5;19(1):14. doi: 10.1186/s12879-018-3614-7.


Urinary LAM grade, culture positivity, and mortality among HIV-infected South African out-patients.

Kubiak RW, Herbeck JT, Coleman SM, Ross D, Freedberg K, Bassett IV, Drain PK.

Int J Tuberc Lung Dis. 2018 Nov 1;22(11):1366-1373. doi: 10.5588/ijtld.18.0099.


Incipient and Subclinical Tuberculosis: a Clinical Review of Early Stages and Progression of Infection.

Drain PK, Bajema KL, Dowdy D, Dheda K, Naidoo K, Schumacher SG, Ma S, Meermeier E, Lewinsohn DM, Sherman DR.

Clin Microbiol Rev. 2018 Jul 18;31(4). pii: e00021-18. doi: 10.1128/CMR.00021-18. Print 2018 Oct. Review.


Correction: Global migration of clinical research during the era of trial registration.

Drain PK, Parker RA, Robine M, Holmes KK, Bassett IV.

PLoS One. 2018 Jun 26;13(6):e0199952. doi: 10.1371/journal.pone.0199952. eCollection 2018.


Dolutegravir for first-line antiretroviral therapy in low-income and middle-income countries: uncertainties and opportunities for implementation and research.

Dorward J, Lessells R, Drain PK, Naidoo K, de Oliveira T, Pillay Y, Abdool Karim SS, Garrett N.

Lancet HIV. 2018 Jul;5(7):e400-e404. doi: 10.1016/S2352-3018(18)30093-6. Epub 2018 Jun 5.


C-reactive protein as a screening test for HIV-associated pulmonary tuberculosis prior to antiretroviral therapy in South Africa.

Shapiro AE, Hong T, Govere S, Thulare H, Moosa MY, Dorasamy A, Wallis CL, Celum CL, Grosset J, Drain PK.

AIDS. 2018 Aug 24;32(13):1811-1820. doi: 10.1097/QAD.0000000000001902.


Operational assessment of point-of-care diagnostics in rural primary healthcare clinics of KwaZulu-Natal, South Africa: a cross-sectional survey.

Mashamba-Thompson TP, Sartorius B, Drain PK.

BMC Health Serv Res. 2018 May 29;18(1):380. doi: 10.1186/s12913-018-3207-6.


Clinic flow for STI, HIV, and TB patients in an urban infectious disease clinic offering point-of-care testing services in Durban, South Africa.

Stime KJ, Garrett N, Sookrajh Y, Dorward J, Dlamini N, Olowolagba A, Sharma M, Barnabas RV, Drain PK.

BMC Health Serv Res. 2018 May 11;18(1):363. doi: 10.1186/s12913-018-3154-2.


Depression and Anxiety as Risk Factors for Delayed Care-Seeking Behavior in Human Immunodeficiency Virus-Infected Individuals in South Africa.

Rane MS, Hong T, Govere S, Thulare H, Moosa MY, Celum C, Drain PK.

Clin Infect Dis. 2018 Oct 15;67(9):1411-1418. doi: 10.1093/cid/ciy309.


Global migration of clinical research during the era of trial registration.

Drain PK, Parker RA, Robine M, Holmes KK, Bassett IV.

PLoS One. 2018 Feb 28;13(2):e0192413. doi: 10.1371/journal.pone.0192413. eCollection 2018. Erratum in: PLoS One. 2018 Jun 26;13(6):e0199952.


The Fogarty International Center at 50: Accomplishments and Priorities for the Next 50 Years.

Drain PK, Holmes KK.

Clin Infect Dis. 2018 Apr 17;66(9):1323-1325. doi: 10.1093/cid/ciy078. No abstract available.


Point-of-care viral load testing and differentiated HIV care.

Dorward J, Drain PK, Garrett N.

Lancet HIV. 2018 Jan;5(1):e8-e9. doi: 10.1016/S2352-3018(17)30211-4. No abstract available.


Clinic-Based Evaluation of a Point-of-Care Creatinine Assay to Screen for Renal Impairment Among HIV-Positive Patients Receiving Tenofovir Disoproxil Fumarate.

Dorward J, Yende-Zuma N, Samsunder N, Karim QA, Drain PK, Garrett N.

J Acquir Immune Defic Syndr. 2018 Apr 1;77(4):e36-e39. doi: 10.1097/QAI.0000000000001613. No abstract available.


Effect of Point-of-Care Diagnostics on Maternal Outcomes in Human Immunodeficiency Virus-Infected Women: Systematic Review and Meta-analysis.

Mashamba-Thompson TP, Morgan RL, Sartorius B, Dennis B, Drain PK, Thabane L.

Point Care. 2017 Jun;16(2):67-77.


Clinic-Based Urinary Lipoarabinomannan as a Biomarker of Clinical Disease Severity and Mortality Among Antiretroviral Therapy-Naive Human Immunodeficiency Virus-Infected Adults in South Africa.

Drain PK, Losina E, Coleman SM, Giddy J, Ross D, Katz JN, Freedberg KA, Bassett IV.

Open Forum Infect Dis. 2017 Aug 14;4(3):ofx167. doi: 10.1093/ofid/ofx167. eCollection 2017 Summer.


Protocol for a randomised controlled implementation trial of point-of-care viral load testing and task shifting: the Simplifying HIV TREAtment and Monitoring (STREAM) study.

Dorward J, Garrett N, Quame-Amaglo J, Samsunder N, Ngobese H, Ngomane N, Moodley P, Mlisana K, Schaafsma T, Donnell D, Barnabas R, Naidoo K, Abdool Karim S, Celum C, Drain PK.

BMJ Open. 2017 Sep 27;7(9):e017507. doi: 10.1136/bmjopen-2017-017507.


Experiential Bloom's Taxonomy learning framework for point-of-care diagnostics training of primary healthcare workers.

Mashamba-Thompson TP, Sartorius B, Stevens FCJ, Drain PK.

Afr J Lab Med. 2016 Sep 30;5(1):449. doi: 10.4102/ajlm.v5i1.449. eCollection 2016. No abstract available.


Evaluating quality management systems for HIV rapid testing services in primary healthcare clinics in rural KwaZulu-Natal, South Africa.

Jaya Z, Drain PK, Mashamba-Thompson TP.

PLoS One. 2017 Aug 22;12(8):e0183044. doi: 10.1371/journal.pone.0183044. eCollection 2017.


Diagnostic accuracy of C-reactive protein for active pulmonary tuberculosis: a meta-analysis.

Yoon C, Chaisson LH, Patel SM, Allen IE, Drain PK, Wilson D, Cattamanchi A.

Int J Tuberc Lung Dis. 2017 Sep 1;21(9):1013-1019. doi: 10.5588/ijtld.17.0078. Review.


A randomized clinical pharmacokinetic trial of Tenofovir in blood, plasma and urine in adults with perfect, moderate and low PrEP adherence: the TARGET study.

Cressey TR, Siriprakaisil O, Klinbuayaem V, Quame-Amaglo J, Kubiak RW, Sukrakanchana PO, Than-In-At K, Baeten J, Sirirungsi W, Cressey R, Drain PK.

BMC Infect Dis. 2017 Jul 14;17(1):496. doi: 10.1186/s12879-017-2593-4.


Preserving the Fogarty International Center - Benefits for Americans and the World.

Drain PK, Subbaraman R, Heimburger DC.

N Engl J Med. 2017 Jul 6;377(1):9-11. doi: 10.1056/NEJMp1704690. Epub 2017 May 24. No abstract available.


Hepatic tuberculosis in human immunodeficiency virus co-infected adults: a case series of South African adults.

Gounder L, Moodley P, Drain PK, Hickey AJ, Moosa MS.

BMC Infect Dis. 2017 Feb 1;17(1):115. doi: 10.1186/s12879-017-2222-2.


Exploring the Case for a Global Alliance for Medical Diagnostics Initiative.

Mugambi ML, Palamountain KM, Gallarda J, Drain PK.

Diagnostics (Basel). 2017 Jan 26;7(1). pii: E8. doi: 10.3390/diagnostics7010008. Review.


Point-of-care diagnostics: extending the laboratory network to reach the last mile.

Drain PK, Rousseau C.

Curr Opin HIV AIDS. 2017 Mar;12(2):175-181. doi: 10.1097/COH.0000000000000351. Review. Erratum in: Curr Opin HIV AIDS. 2017 Sep;12(5):508.


The Emergence of Undergraduate Majors in Global Health: Systematic Review of Programs and Recommendations for Future Directions.

Drain PK, Mock C, Toole D, Rosenwald A, Jehn M, Csordas T, Ferguson L, Waggett C, Obidoa C, Wasserheit JN.

Am J Trop Med Hyg. 2017 Jan 11;96(1):16-23. doi: 10.4269/ajtmh.16-0687. Epub 2016 Nov 14. Review.


Implementation of Point-of-Care Diagnostics in Rural Primary Healthcare Clinics in South Africa: Perspectives of Key Stakeholders.

Mashamba-Thompson TP, Jama NA, Sartorius B, Drain PK, Thompson RM.

Diagnostics (Basel). 2017 Jan 8;7(1). pii: E3. doi: 10.3390/diagnostics7010003.


Rapid urine lipoarabinomannan assay as a clinic-based screening test for active tuberculosis at HIV diagnosis.

Drain PK, Losina E, Coleman SM, Giddy J, Ross D, Katz JN, Bassett IV.

BMC Pulm Med. 2016 Nov 14;16(1):147.


Point-of-Care Diagnostics for Improving Maternal Health in South Africa.

Mashamba-Thompson TP, Sartorius B, Drain PK.

Diagnostics (Basel). 2016 Aug 31;6(3). pii: E31. doi: 10.3390/diagnostics6030031. Review.


Evaluating the accessibility and utility of HIV-related point-of-care diagnostics for maternal health in rural South Africa: a study protocol.

Mashamba-Thompson TP, Drain PK, Sartorius B.

BMJ Open. 2016 Jun 27;6(6):e011155. doi: 10.1136/bmjopen-2016-011155.


Diagnostic Accuracy of the Point-of-Care Xpert HIV-1 Viral Load Assay in a South African HIV Clinic.

Garrett NJ, Drain PK, Werner L, Samsunder N, Abdool Karim SS.

J Acquir Immune Defic Syndr. 2016 Jun 1;72(2):e45-8. doi: 10.1097/QAI.0000000000000978. No abstract available.


Rapid Urine LAM Testing Improves Diagnosis of Expectorated Smear-Negative Pulmonary Tuberculosis in an HIV-endemic Region.

Drain PK, Gounder L, Sahid F, Moosa MY.

Sci Rep. 2016 Feb 11;6:19992. doi: 10.1038/srep19992.


Impact of point-of-care diagnostics on maternal outcomes in HIV-infected women: systematic review and meta-analysis protocol.

Mashamba-Thompson TP, Sartorius B, Thabane L, Shi CX, Drain PK.

BMJ Open. 2016 Jan 27;6(1):e008002. doi: 10.1136/bmjopen-2015-008002.


The arrival of a true point-of-care molecular assay-ready for global implementation?

Drain PK, Garrett NJ.

Lancet Glob Health. 2015 Nov;3(11):e663-4. doi: 10.1016/S2214-109X(15)00186-2. No abstract available.


Implications of Repealing the Cuban Embargo for US Medicine and Public Health.

Drain PK.

Am J Public Health. 2015 Nov;105(11):2210-1. doi: 10.2105/AJPH.2015.302894. Epub 2015 Sep 17. No abstract available.


Author response to "Poor specificity of urinary cryptococcal antigen testing".

Drain PK.

HIV Med. 2018 Jan;19(1):e46. doi: 10.1111/hiv.12318. Epub 2015 Sep 4. No abstract available.


Social support and mental health among adults prior to HIV counseling and testing in Durban, South Africa.

Drain PK, Losina E, Coleman SM, Bogart L, Giddy J, Ross D, Katz JN, Bassett IV.

AIDS Care. 2015;27(10):1231-40. doi: 10.1080/09540121.2015.1046417. Epub 2015 Jul 25.


Prevalence of cryptococcal antigenuria at initial HIV diagnosis in KwaZulu-Natal.

Drain PK, Kleene JM, Coleman SM, Losina E, Katz JN, Giddy J, Ross D, Freedberg KA, Bassett IV.

HIV Med. 2015 Nov;16(10):640-4. doi: 10.1111/hiv.12263. Epub 2015 May 11.


A systematic review of hepatic tuberculosis with considerations in human immunodeficiency virus co-infection.

Hickey AJ, Gounder L, Moosa MY, Drain PK.

BMC Infect Dis. 2015 May 6;15:209. doi: 10.1186/s12879-015-0944-6. Review.


Urine lipoarabinomannan to monitor antituberculosis therapy response and predict mortality in an HIV-endemic region: a prospective cohort study.

Drain PK, Gounder L, Grobler A, Sahid F, Bassett IV, Moosa MY.

BMJ Open. 2015 Apr 15;5(4):e006833. doi: 10.1136/bmjopen-2014-006833.


Ebola: lessons learned from HIV and tuberculosis epidemics.

Drain PK.

Lancet Infect Dis. 2015 Feb;15(2):146-7. doi: 10.1016/S1473-3099(14)71079-5. Epub 2015 Jan 19. No abstract available.


Value of urine lipoarabinomannan grade and second test for optimizing clinic-based screening for HIV-associated pulmonary tuberculosis.

Drain PK, Losina E, Coleman SM, Giddy J, Ross D, Katz JN, Bassett IV.

J Acquir Immune Defic Syndr. 2015 Mar 1;68(3):274-80. doi: 10.1097/QAI.0000000000000436.


Diagnostic delays and clinical decision making with centralized Xpert MTB/RIF testing in Durban, South Africa.

Cohen GM, Drain PK, Noubary F, Cloete C, Bassett IV.

J Acquir Immune Defic Syndr. 2014 Nov 1;67(3):e88-93. doi: 10.1097/QAI.0000000000000309.

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