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Items: 33


Multi-omics Biomarker Pipeline Reveals Elevated Levels of Protein-glutamine Gamma-glutamyltransferase 4 in Seminal Plasma of Prostate Cancer Patients.

Drabovich AP, Saraon P, Drabovich M, Karakosta TD, Dimitromanolakis A, Hyndman ME, Jarvi K, Diamandis EP.

Mol Cell Proteomics. 2019 Sep;18(9):1807-1823. doi: 10.1074/mcp.RA119.001612. Epub 2019 Jun 27.


Identification of TEX101-associated Proteins Through Proteomic Measurement of Human Spermatozoa Homozygous for the Missense Variant rs35033974.

Schiza C, Korbakis D, Jarvi K, Diamandis EP, Drabovich AP.

Mol Cell Proteomics. 2019 Feb;18(2):338-351. doi: 10.1074/mcp.RA118.001170. Epub 2018 Nov 14.


Discovery of a Human Testis-specific Protein Complex TEX101-DPEP3 and Selection of Its Disrupting Antibodies.

Schiza C, Korbakis D, Panteleli E, Jarvi K, Drabovich AP, Diamandis EP.

Mol Cell Proteomics. 2018 Dec;17(12):2480-2495. doi: 10.1074/mcp.RA118.000749. Epub 2018 Aug 10.


Targeted Mass Spectrometry-Based Assays for Relative Quantification of 30 Brain-Related Proteins and Their Clinical Applications.

Begcevic I, Brinc D, Dukic L, Simundic AM, Zavoreo I, Basic Kes V, Martinez-Morillo E, Batruch I, Drabovich AP, Diamandis EP.

J Proteome Res. 2018 Jul 6;17(7):2282-2292. doi: 10.1021/acs.jproteome.7b00768. Epub 2018 Jun 6.


Preclinical evaluation of a TEX101 protein ELISA test for the differential diagnosis of male infertility.

Korbakis D, Schiza C, Brinc D, Soosaipillai A, Karakosta TD, Légaré C, Sullivan R, Mullen B, Jarvi K, Diamandis EP, Drabovich AP.

BMC Med. 2017 Mar 23;15(1):60. doi: 10.1186/s12916-017-0817-5.


Quantification of angiotensin II-regulated proteins in urine of patients with polycystic and other chronic kidney diseases by selected reaction monitoring.

Konvalinka A, Batruch I, Tokar T, Dimitromanolakis A, Reid S, Song X, Pei Y, Drabovich AP, Diamandis EP, Jurisica I, Scholey JW.

Clin Proteomics. 2016 Aug 5;13:16. doi: 10.1186/s12014-016-9117-x. eCollection 2016.


Quantification of Human Kallikrein-Related Peptidases in Biological Fluids by Multiplatform Targeted Mass Spectrometry Assays.

Karakosta TD, Soosaipillai A, Diamandis EP, Batruch I, Drabovich AP.

Mol Cell Proteomics. 2016 Sep;15(9):2863-76. doi: 10.1074/mcp.M115.057695. Epub 2016 Jul 1.


Identification of brain-enriched proteins in the cerebrospinal fluid proteome by LC-MS/MS profiling and mining of the Human Protein Atlas.

Begcevic I, Brinc D, Drabovich AP, Batruch I, Diamandis EP.

Clin Proteomics. 2016 May 15;13:11. doi: 10.1186/s12014-016-9111-3. eCollection 2016.


Dynamics of Protein Expression Reveals Primary Targets and Secondary Messengers of Estrogen Receptor Alpha Signaling in MCF-7 Breast Cancer Cells.

Drabovich AP, Pavlou MP, Schiza C, Diamandis EP.

Mol Cell Proteomics. 2016 Jun;15(6):2093-107. doi: 10.1074/mcp.M115.057257. Epub 2016 Apr 11.


Seminal biomarkers for the evaluation of male infertility.

Bieniek JM, Drabovich AP, Lo KC.

Asian J Androl. 2016 May-Jun;18(3):426-33. doi: 10.4103/1008-682X.175781. Review.


Immunocapture-Selected Reaction Monitoring Screening Facilitates the Development of ELISA for the Measurement of Native TEX101 in Biological Fluids.

Korbakis D, Brinc D, Schiza C, Soosaipillai A, Jarvi K, Drabovich AP, Diamandis EP.

Mol Cell Proteomics. 2015 Jun;14(6):1517-26. doi: 10.1074/mcp.M114.047571. Epub 2015 Mar 26.


Toward an integrated pipeline for protein biomarker development.

Drabovich AP, Martínez-Morillo E, Diamandis EP.

Biochim Biophys Acta. 2015 Jun;1854(6):677-86. doi: 10.1016/j.bbapap.2014.09.006. Epub 2014 Sep 11. Review.


Seminal plasma as a diagnostic fluid for male reproductive system disorders.

Drabovich AP, Saraon P, Jarvi K, Diamandis EP.

Nat Rev Urol. 2014 May;11(5):278-88. doi: 10.1038/nrurol.2014.74. Epub 2014 Apr 8. Review.


Mechanisms of Androgen-Independent Prostate Cancer.

Saraon P, Drabovich AP, Jarvi KA, Diamandis EP.

EJIFCC. 2014 Apr 28;25(1):42-54. eCollection 2014 Apr.


An Emerging Role of TEX101 Protein as a Male Infertility Biomarker.

Schiza CG, Jarv K, Diamandis EP, Drabovich AP.

EJIFCC. 2014 Apr 28;25(1):9-26. eCollection 2014 Apr.


Assessment of peptide chemical modifications on the development of an accurate and precise multiplex selected reaction monitoring assay for apolipoprotein e isoforms.

Martínez-Morillo E, Nielsen HM, Batruch I, Drabovich AP, Begcevic I, Lopez MF, Minthon L, Bu G, Mattsson N, Portelius E, Hansson O, Diamandis EP.

J Proteome Res. 2014 Feb 7;13(2):1077-87. doi: 10.1021/pr401060x. Epub 2014 Jan 14.


Differential diagnosis of azoospermia with proteomic biomarkers ECM1 and TEX101 quantified in seminal plasma.

Drabovich AP, Dimitromanolakis A, Saraon P, Soosaipillai A, Batruch I, Mullen B, Jarvi K, Diamandis EP.

Sci Transl Med. 2013 Nov 20;5(212):212ra160. doi: 10.1126/scitranslmed.3006260.


Determination of an angiotensin II-regulated proteome in primary human kidney cells by stable isotope labeling of amino acids in cell culture (SILAC).

Konvalinka A, Zhou J, Dimitromanolakis A, Drabovich AP, Fang F, Gurley S, Coffman T, John R, Zhang SL, Diamandis EP, Scholey JW.

J Biol Chem. 2013 Aug 23;288(34):24834-47. doi: 10.1074/jbc.M113.485326. Epub 2013 Jul 11.


Quantitative proteomics reveals that enzymes of the ketogenic pathway are associated with prostate cancer progression.

Saraon P, Cretu D, Musrap N, Karagiannis GS, Batruch I, Drabovich AP, van der Kwast T, Mizokami A, Morrissey C, Jarvi K, Diamandis EP.

Mol Cell Proteomics. 2013 Jun;12(6):1589-601. doi: 10.1074/mcp.M112.023887. Epub 2013 Feb 26.


Quantitative proteomic analysis of amniocytes reveals potentially dysregulated molecular networks in Down syndrome.

Cho CK, Drabovich AP, Karagiannis GS, Martínez-Morillo E, Dason S, Dimitromanolakis A, Diamandis EP.

Clin Proteomics. 2013 Feb 8;10(1):2. doi: 10.1186/1559-0275-10-2.


Proteomic profiling of androgen-independent prostate cancer cell lines reveals a role for protein S during the development of high grade and castration-resistant prostate cancer.

Saraon P, Musrap N, Cretu D, Karagiannis GS, Batruch I, Smith C, Drabovich AP, Trudel D, van der Kwast T, Morrissey C, Jarvi KA, Diamandis EP.

J Biol Chem. 2012 Oct 5;287(41):34019-31. doi: 10.1074/jbc.M112.384438. Epub 2012 Aug 20.


Development of a multiplex selected reaction monitoring assay for quantification of biochemical markers of down syndrome in amniotic fluid samples.

Martínez-Morillo E, Cho CK, Drabovich AP, Shaw JL, Soosaipillai A, Diamandis EP.

J Proteome Res. 2012 Jul 6;11(7):3880-7. doi: 10.1021/pr300355a. Epub 2012 Jun 15.


Quantitative analysis of energy metabolic pathways in MCF-7 breast cancer cells by selected reaction monitoring assay.

Drabovich AP, Pavlou MP, Dimitromanolakis A, Diamandis EP.

Mol Cell Proteomics. 2012 Aug;11(8):422-34. doi: 10.1074/mcp.M111.015214. Epub 2012 Apr 25.


Verification of male infertility biomarkers in seminal plasma by multiplex selected reaction monitoring assay.

Drabovich AP, Jarvi K, Diamandis EP.

Mol Cell Proteomics. 2011 Dec;10(12):M110.004127. doi: 10.1074/mcp.M110.004127. Epub 2011 Sep 20.


Verification of a biomarker discovery approach for detection of Down syndrome in amniotic fluid via multiplex selected reaction monitoring (SRM) assay.

Cho CK, Drabovich AP, Batruch I, Diamandis EP.

J Proteomics. 2011 Sep 6;74(10):2052-9. doi: 10.1016/j.jprot.2011.05.025. Epub 2011 May 20.


Platform for establishing interlaboratory reproducibility of selected reaction monitoring-based mass spectrometry peptide assays.

Prakash A, Rezai T, Krastins B, Sarracino D, Athanas M, Russo P, Ross MM, Zhang H, Tian Y, Kulasingam V, Drabovich AP, Smith C, Batruch I, Liotta L, Petricoin E, Diamandis EP, Chan DW, Lopez MF.

J Proteome Res. 2010 Dec 3;9(12):6678-88. doi: 10.1021/pr100821m. Epub 2010 Nov 2.


Combinatorial peptide libraries facilitate development of multiple reaction monitoring assays for low-abundance proteins.

Drabovich AP, Diamandis EP.

J Proteome Res. 2010 Mar 5;9(3):1236-45. doi: 10.1021/pr900729g.


Selection of smart small-molecule ligands: the proof of principle.

Drabovich AP, Berezovski MV, Musheev MU, Krylov SN.

Anal Chem. 2009 Jan 1;81(1):490-4. doi: 10.1021/ac8023813.


Smart aptamers facilitate multi-probe affinity analysis of proteins with ultra-wide dynamic range of measured concentrations.

Drabovich AP, Okhonin V, Berezovski M, Krylov SN.

J Am Chem Soc. 2007 Jun 13;129(23):7260-1. Epub 2007 May 16. No abstract available.


Non-SELEX: selection of aptamers without intermediate amplification of candidate oligonucleotides.

Berezovski MV, Musheev MU, Drabovich AP, Jitkova JV, Krylov SN.

Nat Protoc. 2006;1(3):1359-69.


Dynamic kinetic capillary isoelectric focusing: a powerful tool for studying protein-DNA interactions.

Liu Z, Drabovich AP, Krylov SN, Pawliszyn J.

Anal Chem. 2007 Feb 1;79(3):1097-100.


Selection of smart aptamers by methods of kinetic capillary electrophoresis.

Drabovich AP, Berezovski M, Okhonin V, Krylov SN.

Anal Chem. 2006 May 1;78(9):3171-8.


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