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Items: 1 to 50 of 256

1.

Reversible and Irreversible Modulation of Tubulin Self-Assembly by Intense Nanosecond Pulsed Electric Fields.

Chafai DE, Sulimenko V, Havelka D, Kubínová L, Dráber P, Cifra M.

Adv Mater. 2019 Aug 13:e1903636. doi: 10.1002/adma.201903636. [Epub ahead of print]

PMID:
31408579
2.

TUBG1 missense variants underlying cortical malformations disrupt neuronal locomotion and microtubule dynamics but not neurogenesis.

Ivanova EL, Gilet JG, Sulimenko V, Duchon A, Rudolf G, Runge K, Collins SC, Asselin L, Broix L, Drouot N, Tilly P, Nusbaum P, Vincent A, Magnant W, Skory V, Birling MC, Pavlovic G, Godin JD, Yalcin B, Hérault Y, Dráber P, Chelly J, Hinckelmann MV.

Nat Commun. 2019 May 13;10(1):2129. doi: 10.1038/s41467-019-10081-8.

3.

Regulation of Microtubule Nucleation in Mouse Bone Marrow-Derived Mast Cells by Protein Tyrosine Phosphatase SHP-1.

Klebanovych A, Sládková V, Sulimenko T, Vosecká V, Čapek M, Dráberová E, Dráber P, Sulimenko V.

Cells. 2019 Apr 11;8(4). pii: E345. doi: 10.3390/cells8040345.

4.

The transmembrane adaptor protein NTAL limits mast cell chemotaxis toward prostaglandin E2.

Halova I, Bambouskova M, Draberova L, Bugajev V, Draber P.

Sci Signal. 2018 Nov 13;11(556). pii: eaao4354. doi: 10.1126/scisignal.aao4354.

PMID:
30425164
5.

TBK1 and IKKε prevent TNF-induced cell death by RIPK1 phosphorylation.

Lafont E, Draber P, Rieser E, Reichert M, Kupka S, de Miguel D, Draberova H, von Mässenhausen A, Bhamra A, Henderson S, Wojdyla K, Chalk A, Surinova S, Linkermann A, Walczak H.

Nat Cell Biol. 2018 Dec;20(12):1389-1399. doi: 10.1038/s41556-018-0229-6. Epub 2018 Nov 12.

6.

LUBAC prevents lethal dermatitis by inhibiting cell death induced by TNF, TRAIL and CD95L.

Taraborrelli L, Peltzer N, Montinaro A, Kupka S, Rieser E, Hartwig T, Sarr A, Darding M, Draber P, Haas TL, Akarca A, Marafioti T, Pasparakis M, Bertin J, Gough PJ, Bouillet P, Strasser A, Leverkus M, Silke J, Walczak H.

Nat Commun. 2018 Sep 25;9(1):3910. doi: 10.1038/s41467-018-06155-8.

7.

Positive and Negative Regulatory Roles of C-Terminal Src Kinase (CSK) in FcεRI-Mediated Mast Cell Activation, Independent of the Transmembrane Adaptor PAG/CSK-Binding Protein.

Potuckova L, Draberova L, Halova I, Paulenda T, Draber P.

Front Immunol. 2018 Aug 2;9:1771. doi: 10.3389/fimmu.2018.01771. eCollection 2018.

8.

Mast Cell Activation and Microtubule Organization Are Modulated by Miltefosine Through Protein Kinase C Inhibition.

Rubíková Z, Sulimenko V, Paulenda T, Dráber P.

Front Immunol. 2018 Jul 9;9:1563. doi: 10.3389/fimmu.2018.01563. eCollection 2018.

9.

Expression of γ-tubulin in non-small cell lung cancer and effect on patient survival.

Maounis NF, Dráberová E, Trakas N, Chorti M, Riga D, Tzannis K, Kanakis M, Voralu K, Ellina E, Mahera E, Demonakou M, Lioulias A, Dráber P, Katsetos CD.

Histol Histopathol. 2019 Jan;34(1):81-90. doi: 10.14670/HH-18-027. Epub 2018 Jul 16.

PMID:
30010174
10.

Estradiol dimer inhibits tubulin polymerization and microtubule dynamics.

Jurášek M, Černohorská M, Řehulka J, Spiwok V, Sulimenko T, Dráberová E, Darmostuk M, Gurská S, Frydrych I, Buriánová R, Ruml T, Hajdúch M, Bartůněk P, Dráber P, Džubák P, Drašar PB, Sedlák D.

J Steroid Biochem Mol Biol. 2018 Oct;183:68-79. doi: 10.1016/j.jsbmb.2018.05.008. Epub 2018 May 24.

PMID:
29803726
11.

Strong homeostatic TCR signals induce formation of self-tolerant virtual memory CD8 T cells.

Drobek A, Moudra A, Mueller D, Huranova M, Horkova V, Pribikova M, Ivanek R, Oberle S, Zehn D, McCoy KD, Draber P, Stepanek O.

EMBO J. 2018 Jul 13;37(14). pii: e98518. doi: 10.15252/embj.201798518. Epub 2018 May 11.

12.

LUBAC is essential for embryogenesis by preventing cell death and enabling haematopoiesis.

Peltzer N, Darding M, Montinaro A, Draber P, Draberova H, Kupka S, Rieser E, Fisher A, Hutchinson C, Taraborrelli L, Hartwig T, Lafont E, Haas TL, Shimizu Y, Böiers C, Sarr A, Rickard J, Alvarez-Diaz S, Ashworth MT, Beal A, Enver T, Bertin J, Kaiser W, Strasser A, Silke J, Bouillet P, Walczak H.

Nature. 2018 May;557(7703):112-117. doi: 10.1038/s41586-018-0064-8. Epub 2018 Apr 25.

13.

γ-Tubulin has a conserved intrinsic property of self-polymerization into double stranded filaments and fibrillar networks.

Chumová J, Trögelová L, Kourová H, Volc J, Sulimenko V, Halada P, Kučera O, Benada O, Kuchařová A, Klebanovych A, Dráber P, Daniel G, Binarová P.

Biochim Biophys Acta Mol Cell Res. 2018 May;1865(5):734-748. doi: 10.1016/j.bbamcr.2018.02.009. Epub 2018 Feb 27.

14.

Changing the threshold-Signals and mechanisms of mast cell priming.

Halova I, Rönnberg E, Draberova L, Vliagoftis H, Nilsson GP, Draber P.

Immunol Rev. 2018 Mar;282(1):73-86. doi: 10.1111/imr.12625. Review.

PMID:
29431203
15.

Editorial.

Stick R, Dráber P.

Protoplasma. 2017 May;254(3):1141-1142. doi: 10.1007/s00709-017-1093-0. Epub 2017 Mar 16. No abstract available.

PMID:
28299513
16.

The linear ubiquitin chain assembly complex regulates TRAIL-induced gene activation and cell death.

Lafont E, Kantari-Mimoun C, Draber P, De Miguel D, Hartwig T, Reichert M, Kupka S, Shimizu Y, Taraborrelli L, Spit M, Sprick MR, Walczak H.

EMBO J. 2017 May 2;36(9):1147-1166. doi: 10.15252/embj.201695699. Epub 2017 Mar 3.

17.

Positive and Negative Signals in Mast Cell Activation.

Bulfone-Paus S, Nilsson G, Draber P, Blank U, Levi-Schaffer F.

Trends Immunol. 2017 Sep;38(9):657-667. doi: 10.1016/j.it.2017.01.008. Epub 2017 Feb 20. Review.

PMID:
28254170
18.

The TRAIL-Induced Cancer Secretome Promotes a Tumor-Supportive Immune Microenvironment via CCR2.

Hartwig T, Montinaro A, von Karstedt S, Sevko A, Surinova S, Chakravarthy A, Taraborrelli L, Draber P, Lafont E, Arce Vargas F, El-Bahrawy MA, Quezada SA, Walczak H.

Mol Cell. 2017 Feb 16;65(4):730-742.e5. doi: 10.1016/j.molcel.2017.01.021.

19.

Differential expression of human γ-tubulin isotypes during neuronal development and oxidative stress points to a γ-tubulin-2 prosurvival function.

Dráberová E, Sulimenko V, Vinopal S, Sulimenko T, Sládková V, D'Agostino L, Sobol M, Hozák P, Křen L, Katsetos CD, Dráber P.

FASEB J. 2017 May;31(5):1828-1846. doi: 10.1096/fj.201600846RR. Epub 2017 Jan 24.

PMID:
28119396
20.

Corrigendum to "GIT1/betaPIX signaling proteins and PAK1 kinase regulate microtubule nucleation" [Biochim. Biophys. Acta 1863/6PA (2016) 1282-1297].

Černohorská M, Sulimenko V, Hájková Z, Sulimenko T, Sládková V, Vinopal S, Dráberová E, Dráber P.

Biochim Biophys Acta Mol Cell Res. 2017 Apr;1864(4):747. doi: 10.1016/j.bbamcr.2017.01.002. Epub 2017 Jan 15. No abstract available.

21.

Regulation of microtubule nucleation mediated by γ-tubulin complexes.

Sulimenko V, Hájková Z, Klebanovych A, Dráber P.

Protoplasma. 2017 May;254(3):1187-1199. doi: 10.1007/s00709-016-1070-z. Epub 2017 Jan 10. Review.

PMID:
28074286
22.

--LUBAC deficiency perturbs TLR3 signaling to cause immunodeficiency and autoinflammation.

Zinngrebe J, Rieser E, Taraborrelli L, Peltzer N, Hartwig T, Ren H, Kovács I, Endres C, Draber P, Darding M, von Karstedt S, Lemke J, Dome B, Bergmann M, Ferguson BJ, Walczak H.

J Exp Med. 2016 Nov 14;213(12):2671-2689. Epub 2016 Oct 24.

23.

NEMO regulates a cell death switch in TNF signaling by inhibiting recruitment of RIPK3 to the cell death-inducing complex II.

Pescatore A, Esposito E, Draber P, Walczak H, Ursini MV.

Cell Death Dis. 2016 Aug 25;7(8):e2346. doi: 10.1038/cddis.2016.245.

24.

SPATA2-Mediated Binding of CYLD to HOIP Enables CYLD Recruitment to Signaling Complexes.

Kupka S, De Miguel D, Draber P, Martino L, Surinova S, Rittinger K, Walczak H.

Cell Rep. 2016 Aug 30;16(9):2271-80. doi: 10.1016/j.celrep.2016.07.086. Epub 2016 Aug 18.

25.

Profilin connects actin assembly with microtubule dynamics.

Nejedla M, Sadi S, Sulimenko V, de Almeida FN, Blom H, Draber P, Aspenström P, Karlsson R.

Mol Biol Cell. 2016 Aug 1;27(15):2381-93. doi: 10.1091/mbc.E15-11-0799. Epub 2016 Jun 15.

26.

Tetraspanins and Transmembrane Adaptor Proteins As Plasma Membrane Organizers-Mast Cell Case.

Halova I, Draber P.

Front Cell Dev Biol. 2016 May 10;4:43. doi: 10.3389/fcell.2016.00043. eCollection 2016. Review.

27.

GIT1/βPIX signaling proteins and PAK1 kinase regulate microtubule nucleation.

Černohorská M, Sulimenko V, Hájková Z, Sulimenko T, Sládková V, Vinopal S, Dráberová E, Dráber P.

Biochim Biophys Acta. 2016 Jun;1863(6 Pt A):1282-97. doi: 10.1016/j.bbamcr.2016.03.016. Epub 2016 Mar 22. Erratum in: Biochim Biophys Acta. 2017 Apr;1864(4):747.

28.

The role of ORMDL proteins, guardians of cellular sphingolipids, in asthma.

Paulenda T, Draber P.

Allergy. 2016 Jul;71(7):918-30. doi: 10.1111/all.12877. Epub 2016 Mar 29. Review.

PMID:
26969910
29.

New Regulatory Roles of Galectin-3 in High-Affinity IgE Receptor Signaling.

Bambouskova M, Polakovicova I, Halova I, Goel G, Draberova L, Bugajev V, Doan A, Utekal P, Gardet A, Xavier RJ, Draber P.

Mol Cell Biol. 2016 Apr 15;36(9):1366-82. doi: 10.1128/MCB.00064-16. Print 2016 May.

30.

Formation and removal of poly-ubiquitin chains in the regulation of tumor necrosis factor-induced gene activation and cell death.

Kupka S, Reichert M, Draber P, Walczak H.

FEBS J. 2016 Jul;283(14):2626-39. doi: 10.1111/febs.13644. Epub 2016 Jan 24. Review.

31.

LUBAC-Recruited CYLD and A20 Regulate Gene Activation and Cell Death by Exerting Opposing Effects on Linear Ubiquitin in Signaling Complexes.

Draber P, Kupka S, Reichert M, Draberova H, Lafont E, de Miguel D, Spilgies L, Surinova S, Taraborrelli L, Hartwig T, Rieser E, Martino L, Rittinger K, Walczak H.

Cell Rep. 2015 Dec 15;13(10):2258-72. doi: 10.1016/j.celrep.2015.11.009. Epub 2015 Dec 6.

32.

Ethanol Inhibits High-Affinity Immunoglobulin E Receptor (FcεRI) Signaling in Mast Cells by Suppressing the Function of FcεRI-Cholesterol Signalosome.

Draberova L, Paulenda T, Halova I, Potuckova L, Bugajev V, Bambouskova M, Tumova M, Draber P.

PLoS One. 2015 Dec 14;10(12):e0144596. doi: 10.1371/journal.pone.0144596. eCollection 2015.

33.

Negative regulatory roles of ORMDL3 in the FcεRI-triggered expression of proinflammatory mediators and chemotactic response in murine mast cells.

Bugajev V, Halova I, Draberova L, Bambouskova M, Potuckova L, Draberova H, Paulenda T, Junyent S, Draber P.

Cell Mol Life Sci. 2016 Mar;73(6):1265-85. doi: 10.1007/s00018-015-2047-3. Epub 2015 Sep 25.

PMID:
26407610
34.

Overexpression and Nucleolar Localization of γ-Tubulin Small Complex Proteins GCP2 and GCP3 in Glioblastoma.

Dráberová E, D'Agostino L, Caracciolo V, Sládková V, Sulimenko T, Sulimenko V, Sobol M, Maounis NF, Tzelepis E, Mahera E, Křen L, Legido A, Giordano A, Mörk S, Hozák P, Dráber P, Katsetos CD.

J Neuropathol Exp Neurol. 2015 Jul;74(7):723-42. doi: 10.1097/NEN.0000000000000212.

PMID:
26079448
35.

Emerging microtubule targets in glioma therapy.

Katsetos CD, Reginato MJ, Baas PW, D'Agostino L, Legido A, Tuszyn Ski JA, Dráberová E, Dráber P.

Semin Pediatr Neurol. 2015 Mar;22(1):49-72. doi: 10.1016/j.spen.2015.03.009. Epub 2015 Apr 4. Review.

PMID:
25976261
36.

Signal transduction and chemotaxis in mast cells.

Draber P, Halova I, Polakovicova I, Kawakami T.

Eur J Pharmacol. 2016 May 5;778:11-23. doi: 10.1016/j.ejphar.2015.02.057. Epub 2015 May 2. Review.

37.

Microtubule nucleation in mouse bone marrow-derived mast cells is regulated by the concerted action of GIT1/βPIX proteins and calcium.

Sulimenko V, Hájková Z, Černohorská M, Sulimenko T, Sládková V, Dráberová L, Vinopal S, Dráberová E, Dráber P.

J Immunol. 2015 May 1;194(9):4099-111. doi: 10.4049/jimmunol.1402459. Epub 2015 Mar 27.

38.

Membrane-cytoskeleton dynamics in the course of mast cell activation.

Dráber P, Dráber P.

Methods Mol Biol. 2015;1220:219-37. doi: 10.1007/978-1-4939-1568-2_14.

PMID:
25388254
39.

Real-time PCR-based genotyping from whole blood using Taq DNA polymerase and a buffer supplemented with 1,2-propanediol and trehalose.

Utekal P, Kocanda L, Matousek P, Wagner P, Bugajev V, Draber P.

J Immunol Methods. 2015 Jan;416:178-82. doi: 10.1016/j.jim.2014.09.006. Epub 2014 Oct 8.

PMID:
25305365
40.

HOIP deficiency causes embryonic lethality by aberrant TNFR1-mediated endothelial cell death.

Peltzer N, Rieser E, Taraborrelli L, Draber P, Darding M, Pernaute B, Shimizu Y, Sarr A, Draberova H, Montinaro A, Martinez-Barbera JP, Silke J, Rodriguez TA, Walczak H.

Cell Rep. 2014 Oct 9;9(1):153-165. doi: 10.1016/j.celrep.2014.08.066. Epub 2014 Oct 2.

41.

Transmembrane adaptor protein PAG/CBP is involved in both positive and negative regulation of mast cell signaling.

Draberova L, Bugajev V, Potuckova L, Halova I, Bambouskova M, Polakovicova I, Xavier RJ, Seed B, Draber P.

Mol Cell Biol. 2014 Dec 1;34(23):4285-300. doi: 10.1128/MCB.00983-14. Epub 2014 Sep 22.

42.

Multiple regulatory roles of the mouse transmembrane adaptor protein NTAL in gene transcription and mast cell physiology.

Polakovicova I, Draberova L, Simicek M, Draber P.

PLoS One. 2014 Aug 25;9(8):e105539. doi: 10.1371/journal.pone.0105539. eCollection 2014.

43.

Microscopy assays for evaluation of mast cell migration and chemotaxis.

Bambousková M, Hájková Z, Dráber P, Dráber P.

Methods Mol Biol. 2014;1192:161-76. doi: 10.1007/978-1-4939-1173-8_12.

PMID:
25149491
44.

TRAIL-R2-specific antibodies and recombinant TRAIL can synergise to kill cancer cells.

Tuthill MH, Montinaro A, Zinngrebe J, Prieske K, Draber P, Prieske S, Newsom-Davis T, von Karstedt S, Graves J, Walczak H.

Oncogene. 2015 Apr 16;34(16):2138-2144. doi: 10.1038/onc.2014.156. Epub 2014 Jun 9.

45.

Molecular targets on mast cells and basophils for novel therapies.

Harvima IT, Levi-Schaffer F, Draber P, Friedman S, Polakovicova I, Gibbs BF, Blank U, Nilsson G, Maurer M.

J Allergy Clin Immunol. 2014 Sep;134(3):530-44. doi: 10.1016/j.jaci.2014.03.007. Epub 2014 Apr 24. Review.

PMID:
24767877
46.

Stabilization of protein by freeze-drying in the presence of trehalose: a case study of tubulin.

Dráber P, Sulimenko V, Sulimenko T, Dráberová E.

Methods Mol Biol. 2014;1129:443-58. doi: 10.1007/978-1-62703-977-2_32.

PMID:
24648093
47.

Gold nanoparticle-based immuno-PCR for detection of tau protein in cerebrospinal fluid.

Stegurová L, Dráberová E, Bartos A, Dráber P, Rípová D, Dráber P.

J Immunol Methods. 2014 Apr;406:137-42. doi: 10.1016/j.jim.2014.03.007. Epub 2014 Mar 15.

PMID:
24642424
48.

Palmitoylated transmembrane adaptor proteins in leukocyte signaling.

Stepanek O, Draber P, Horejsi V.

Cell Signal. 2014 May;26(5):895-902. doi: 10.1016/j.cellsig.2014.01.007. Epub 2014 Jan 15. Review.

PMID:
24440308
49.

Mitochondrial dysfunction in gliomas.

Katsetos CD, Anni H, Dráber P.

Semin Pediatr Neurol. 2013 Sep;20(3):216-27. doi: 10.1016/j.spen.2013.09.003.

PMID:
24331363
50.

Quantification of α-tubulin isotypes by sandwich ELISA with signal amplification through biotinyl-tyramide or immuno-PCR.

Dráberová E, Stegurová L, Sulimenko V, Hájková Z, Dráber P, Dráber P.

J Immunol Methods. 2013 Sep 30;395(1-2):63-70. doi: 10.1016/j.jim.2013.07.001. Epub 2013 Jul 10.

PMID:
23851142

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