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Items: 1 to 50 of 84

1.

Concomitant PPARα and FXR Activation as a Putative Mechanism of NASH Improvement after Gastric Bypass Surgery: a GEO Datasets Analysis.

Mazzini GS, Khoraki J, Dozmorov M, Browning MG, Wijesinghe D, Wolfe L, Gurski RR, Campos GM.

J Gastrointest Surg. 2018 Sep 11. doi: 10.1007/s11605-018-3938-z. [Epub ahead of print]

PMID:
30206765
2.

The cell cycle regulatory DREAM complex is disrupted by high expression of oncogenic B-Myb.

Iness AN, Felthousen J, Ananthapadmanabhan V, Sesay F, Saini S, Guiley KZ, Rubin SM, Dozmorov M, Litovchick L.

Oncogene. 2018 Sep 11. doi: 10.1038/s41388-018-0490-y. [Epub ahead of print]

PMID:
30206359
3.

Astrocyte elevated gene-1 (AEG-1) regulates macrophage activation in hepatocellular carcinogenesis.

Robertson CL, Mendoza RG, Jariwala N, Dozmorov M, Mukhopadhyay ND, Subler MA, Windle JJ, Lai Z, Fisher PB, Ghosh S, Sarkar D.

Cancer Res. 2018 Sep 4. pii: canres.0659.2018. doi: 10.1158/0008-5472.CAN-18-0659. [Epub ahead of print]

PMID:
30181179
4.

Trans-Ethnic Mapping of BANK1 Identifies Two Independent SLE-Risk Linkage Groups Enriched for Co-Transcriptional Splicing Marks.

Martínez-Bueno M, Oparina N, Dozmorov MG, Marion MC, Comeau ME, Gilkeson G, Kamen D, Weisman M, Salmon J, McCune JW, Harley JB, Kimberly R, James JA, Merrill J, Montgomery C, Langefeld CD, Alarcón-Riquelme ME.

Int J Mol Sci. 2018 Aug 8;19(8). pii: E2331. doi: 10.3390/ijms19082331.

5.

HiCcompare: an R-package for joint normalization and comparison of HI-C datasets.

Stansfield JC, Cresswell KG, Vladimirov VI, Dozmorov MG.

BMC Bioinformatics. 2018 Jul 31;19(1):279. doi: 10.1186/s12859-018-2288-x.

6.

HDAC2-dependent Antipsychotic-like Effects of Chronic Treatment with the HDAC Inhibitor SAHA in Mice.

de la Fuente Revenga M, Ibi D, Saunders JM, Cuddy T, Ijaz MK, Toneatti R, Kurita M, Holloway T, Shen L, Seto J, Dozmorov MG, González-Maeso J.

Neuroscience. 2018 Sep 15;388:102-117. doi: 10.1016/j.neuroscience.2018.07.010. Epub 2018 Jul 17.

PMID:
30025863
7.

Disease classification: from phenotypic similarity to integrative genomics and beyond.

Dozmorov MG.

Brief Bioinform. 2018 Jun 22. doi: 10.1093/bib/bby049. [Epub ahead of print]

PMID:
29939197
8.

Targeted inhibition of histone H3K27 demethylation is effective in high-risk neuroblastoma.

Lochmann TL, Powell KM, Ham J, Floros KV, Heisey DAR, Kurupi RIJ, Calbert ML, Ghotra MS, Greninger P, Dozmorov M, Gowda M, Souers AJ, Reynolds CP, Benes CH, Faber AC.

Sci Transl Med. 2018 May 16;10(441). pii: eaao4680. doi: 10.1126/scitranslmed.aao4680.

PMID:
29769286
9.

Gene expression profiling of primary human type I alveolar epithelial cells exposed to Bacillus anthracis spores reveals induction of neutrophil and monocyte chemokines.

Booth JL, Duggan ES, Patel VI, Wu W, Burian DM, Hutchings DC, White VL, Coggeshall KM, Dozmorov MG, Metcalf JP.

Microb Pathog. 2018 Aug;121:9-21. doi: 10.1016/j.micpath.2018.04.039. Epub 2018 Apr 25.

PMID:
29704667
10.

Associations between maternal cytokine levels during gestation and measures of child cognitive abilities and executive functioning.

Dozmorov MG, Bilbo SD, Kollins SH, Zucker N, Do EK, Schechter JC, Zhang JJ, Murphy SK, Hoyo C, Fuemmeler BF.

Brain Behav Immun. 2018 May;70:390-397. doi: 10.1016/j.bbi.2018.03.029. Epub 2018 Mar 26.

PMID:
29588230
11.

Characterizing the efficacy of cancer therapeutics in patient-derived xenograft models of metastatic breast cancer.

Turner TH, Alzubi MA, Sohal SS, Olex AL, Dozmorov MG, Harrell JC.

Breast Cancer Res Treat. 2018 Jul;170(2):221-234. doi: 10.1007/s10549-018-4748-4. Epub 2018 Mar 12.

PMID:
29532339
12.

Coamplification of miR-4728 protects HER2-amplified breast cancers from targeted therapy.

Floros KV, Lochmann TL, Hu B, Monterrubio C, Hughes MT, Wells JD, Morales CB, Ghotra MS, Costa C, Souers AJ, Boikos SA, Leverson JD, Tan M, Serra V, Koblinski JE, Arribas J, Prat A, Paré L, Miller TW, Dozmorov MG, Harada H, Windle BE, Scaltriti M, Faber AC.

Proc Natl Acad Sci U S A. 2018 Mar 13;115(11):E2594-E2603. doi: 10.1073/pnas.1717820115. Epub 2018 Feb 23.

13.

Proceedings of the 2017 MidSouth Computational Biology and Bioinformatics Society (MCBIOS) Conference.

Wren JD, Dozmorov MG, Toby I, Nanduri B, Homayouni R, Manda P, Thakkar S.

BMC Bioinformatics. 2017 Dec 28;18(Suppl 14):498. doi: 10.1186/s12859-017-1887-2. No abstract available.

14.

The role of epigenomics in personalized medicine.

Kronfol MM, Dozmorov MG, Huang R, Slattum PW, McClay JL.

Expert Rev Precis Med Drug Dev. 2017;2(1):33-45. doi: 10.1080/23808993.2017.1284557. Epub 2017 Jan 31.

15.

Bile acids as global regulators of hepatic nutrient metabolism.

Hylemon PB, Takabe K, Dozmorov M, Nagahashi M, Zhou H.

Liver Res. 2017 Jun;1(1):10-16. doi: 10.1016/j.livres.2017.03.002. Epub 2017 Apr 26.

16.

Epithelial-to-Mesenchymal Transition Antagonizes Response to Targeted Therapies in Lung Cancer by Suppressing BIM.

Song KA, Niederst MJ, Lochmann TL, Hata AN, Kitai H, Ham J, Floros KV, Hicks MA, Hu H, Mulvey HE, Drier Y, Heisey DAR, Hughes MT, Patel NU, Lockerman EL, Garcia A, Gillepsie S, Archibald HL, Gomez-Caraballo M, Nulton TJ, Windle BE, Piotrowska Z, Sahingur SE, Taylor SM, Dozmorov M, Sequist LV, Bernstein B, Ebi H, Engelman JA, Faber AC.

Clin Cancer Res. 2018 Jan 1;24(1):197-208. doi: 10.1158/1078-0432.CCR-17-1577. Epub 2017 Oct 19.

PMID:
29051323
17.

Epigenomic annotation-based interpretation of genomic data: from enrichment analysis to machine learning.

Dozmorov MG.

Bioinformatics. 2017 Oct 15;33(20):3323-3330. doi: 10.1093/bioinformatics/btx414.

PMID:
29028263
18.

Identification of breast cancer associated variants that modulate transcription factor binding.

Liu Y, Walavalkar NM, Dozmorov MG, Rich SS, Civelek M, Guertin MJ.

PLoS Genet. 2017 Sep 28;13(9):e1006761. doi: 10.1371/journal.pgen.1006761. eCollection 2017 Sep.

19.

Sexually divergent DNA methylation patterns with hippocampal aging.

Masser DR, Hadad N, Porter HL, Mangold CA, Unnikrishnan A, Ford MM, Giles CB, Georgescu C, Dozmorov MG, Wren JD, Richardson A, Stanford DR, Freeman WM.

Aging Cell. 2017 Dec;16(6):1342-1352. doi: 10.1111/acel.12681. Epub 2017 Sep 25.

20.

Effects of DNA Methylation on Progression to Interstitial Fibrosis and Tubular Atrophy in Renal Allograft Biopsies: A Multi-Omics Approach.

Bontha SV, Maluf DG, Archer KJ, Dumur CI, Dozmorov MG, King AL, Akalin E, Mueller TF, Gallon L, Mas VR.

Am J Transplant. 2017 Dec;17(12):3060-3075. doi: 10.1111/ajt.14372. Epub 2017 Jul 8.

PMID:
28556588
21.

Current Developments in Machine Learning Techniques in Biological Data Mining.

Dumancas GG, Adrianto I, Bello G, Dozmorov M.

Bioinform Biol Insights. 2017 Mar 22;11:1177932216687545. doi: 10.1177/1177932216687545. eCollection 2017.

22.

A novel role of astrocyte elevated gene-1 (AEG-1) in regulating nonalcoholic steatohepatitis (NASH).

Srivastava J, Robertson CL, Ebeid K, Dozmorov M, Rajasekaran D, Mendoza R, Siddiq A, Akiel MA, Jariwala N, Shen XN, Windle JJ, Subler MA, Mukhopadhyay ND, Giashuddin S, Ghosh S, Lai Z, Chen Y, Fisher PB, Salem AK, Sanyal AJ, Sarkar D.

Hepatology. 2017 Aug;66(2):466-480. doi: 10.1002/hep.29230. Epub 2017 Jun 30.

23.

Age-associated DNA methylation changes in naive CD4+ T cells suggest an evolving autoimmune epigenotype in aging T cells.

Dozmorov MG, Coit P, Maksimowicz-McKinnon K, Sawalha AH.

Epigenomics. 2017 Apr;9(4):429-445. doi: 10.2217/epi-2016-0143. Epub 2017 Mar 21.

24.

Analysis of The Cancer Genome Atlas sequencing data reveals novel properties of the human papillomavirus 16 genome in head and neck squamous cell carcinoma.

Nulton TJ, Olex AL, Dozmorov M, Morgan IM, Windle B.

Oncotarget. 2017 Mar 14;8(11):17684-17699. doi: 10.18632/oncotarget.15179.

25.

Angiopoietin pathway gene expression associated with poor breast cancer survival.

Ramanathan R, Olex AL, Dozmorov M, Bear HD, Fernandez LJ, Takabe K.

Breast Cancer Res Treat. 2017 Feb;162(1):191-198. doi: 10.1007/s10549-017-4102-2. Epub 2017 Jan 6.

26.

Transcriptional Classification and Functional Characterization of Human Airway Macrophage and Dendritic Cell Subsets.

Patel VI, Booth JL, Duggan ES, Cate S, White VL, Hutchings D, Kovats S, Burian DM, Dozmorov M, Metcalf JP.

J Immunol. 2017 Feb 1;198(3):1183-1201. doi: 10.4049/jimmunol.1600777. Epub 2016 Dec 28.

28.

Proceedings of the 2016 MidSouth Computational Biology and Bioinformatics Society (MCBIOS) Conference.

Wren JD, Toby I, Hong H, Nanduri B, Kaundal R, Dozmorov MG, Thakkar S.

BMC Bioinformatics. 2016 Oct 6;17(Suppl 13):356. No abstract available.

29.

Expression and methylation data from SLE patient and healthy control blood samples subdivided with respect to ARID3a levels.

Ward JM, Ratliff ML, Dozmorov MG, Wiley G, Guthridge JM, Gaffney PM, James JA, Webb CF.

Data Brief. 2016 Aug 31;9:213-9. doi: 10.1016/j.dib.2016.08.049. eCollection 2016 Dec.

30.

Human effector B lymphocytes express ARID3a and secrete interferon alpha.

Ward JM, Ratliff ML, Dozmorov MG, Wiley G, Guthridge JM, Gaffney PM, James JA, Webb CF.

J Autoimmun. 2016 Dec;75:130-140. doi: 10.1016/j.jaut.2016.08.003. Epub 2016 Aug 10.

31.

Hypomethylation coordinates antagonistically with hypermethylation in cancer development: a case study of leukemia.

Kushwaha G, Dozmorov M, Wren JD, Qiu J, Shi H, Xu D.

Hum Genomics. 2016 Jul 25;10 Suppl 2:18. doi: 10.1186/s40246-016-0071-5.

32.

GenomeRunner web server: regulatory similarity and differences define the functional impact of SNP sets.

Dozmorov MG, Cara LR, Giles CB, Wren JD.

Bioinformatics. 2016 Aug 1;32(15):2256-63. doi: 10.1093/bioinformatics/btw169. Epub 2016 Apr 1.

33.

Establishing an analytic pipeline for genome-wide DNA methylation.

Wright ML, Dozmorov MG, Wolen AR, Jackson-Cook C, Starkweather AR, Lyon DE, York TP.

Clin Epigenetics. 2016 Apr 27;8:45. doi: 10.1186/s13148-016-0212-7. eCollection 2016. Review.

34.

Epigenetic Reprogramming in Naive CD4+ T Cells Favoring T Cell Activation and Non-Th1 Effector T Cell Immune Response as an Early Event in Lupus Flares.

Coit P, Dozmorov MG, Merrill JT, McCune WJ, Maksimowicz-McKinnon K, Wren JD, Sawalha AH.

Arthritis Rheumatol. 2016 Sep;68(9):2200-9. doi: 10.1002/art.39720.

35.

Staphylococcal Nuclease and Tudor Domain Containing 1 (SND1 Protein) Promotes Hepatocarcinogenesis by Inhibiting Monoglyceride Lipase (MGLL).

Rajasekaran D, Jariwala N, Mendoza RG, Robertson CL, Akiel MA, Dozmorov M, Fisher PB, Sarkar D.

J Biol Chem. 2016 May 13;291(20):10736-46. doi: 10.1074/jbc.M116.715359. Epub 2016 Mar 20.

36.

Exploitation of the Apoptosis-Primed State of MYCN-Amplified Neuroblastoma to Develop a Potent and Specific Targeted Therapy Combination.

Ham J, Costa C, Sano R, Lochmann TL, Sennott EM, Patel NU, Dastur A, Gomez-Caraballo M, Krytska K, Hata AN, Floros KV, Hughes MT, Jakubik CT, Heisey DA, Ferrell JT, Bristol ML, March RJ, Yates C, Hicks MA, Nakajima W, Gowda M, Windle BE, Dozmorov MG, Garnett MJ, McDermott U, Harada H, Taylor SM, Morgan IM, Benes CH, Engelman JA, Mossé YP, Faber AC.

Cancer Cell. 2016 Feb 8;29(2):159-72. doi: 10.1016/j.ccell.2016.01.002.

37.

High-density genotyping of immune-related loci identifies new SLE risk variants in individuals with Asian ancestry.

Sun C, Molineros JE, Looger LL, Zhou XJ, Kim K, Okada Y, Ma J, Qi YY, Kim-Howard X, Motghare P, Bhattarai K, Adler A, Bang SY, Lee HS, Kim TH, Kang YM, Suh CH, Chung WT, Park YB, Choe JY, Shim SC, Kochi Y, Suzuki A, Kubo M, Sumida T, Yamamoto K, Lee SS, Kim YJ, Han BG, Dozmorov M, Kaufman KM, Wren JD, Harley JB, Shen N, Chua KH, Zhang H, Bae SC, Nath SK.

Nat Genet. 2016 Mar;48(3):323-30. doi: 10.1038/ng.3496. Epub 2016 Jan 25.

38.

High density methylation QTL analysis in human blood via next-generation sequencing of the methylated genomic DNA fraction.

McClay JL, Shabalin AA, Dozmorov MG, Adkins DE, Kumar G, Nerella S, Clark SL, Bergen SE; Swedish Schizophrenia Consortium, Hultman CM, Magnusson PK, Sullivan PF, Aberg KA, van den Oord EJ.

Genome Biol. 2015 Dec 23;16:291. doi: 10.1186/s13059-015-0842-7.

39.

A Whole Methylome CpG-SNP Association Study of Psychosis in Blood and Brain Tissue.

van den Oord EJ, Clark SL, Xie LY, Shabalin AA, Dozmorov MG, Kumar G; Swedish Schizophrenia Consortium, Vladimirov VI, Magnusson PK, Aberg KA.

Schizophr Bull. 2016 Jul;42(4):1018-26. doi: 10.1093/schbul/sbv182. Epub 2015 Dec 9.

40.

B-Cell and Monocyte Contribution to Systemic Lupus Erythematosus Identified by Cell-Type-Specific Differential Expression Analysis in RNA-Seq Data.

Dozmorov MG, Dominguez N, Bean K, Macwana SR, Roberts V, Glass E, James JA, Guthridge JM.

Bioinform Biol Insights. 2015 Oct 8;9(Suppl 3):11-9. doi: 10.4137/BBI.S29470. eCollection 2015.

41.

Epigenomic functional characterization of genetic susceptibility variants in systemic vasculitis.

Sawalha AH, Dozmorov MG.

J Autoimmun. 2016 Feb;67:76-81. doi: 10.1016/j.jaut.2015.10.002. Epub 2015 Oct 20.

42.

Proceedings of the 2015 MidSouth Computational Biology and Bioinformatics Society (MCBIOS) Conference.

Wren JD, Thakkar S, Homayouni R, Johann DJ, Dozmorov MG.

BMC Bioinformatics. 2015;16 Suppl 13:S1. doi: 10.1186/1471-2105-16-S13-S1. Epub 2015 Sep 25. No abstract available.

43.

Detrimental effects of duplicate reads and low complexity regions on RNA- and ChIP-seq data.

Dozmorov MG, Adrianto I, Giles CB, Glass E, Glenn SB, Montgomery C, Sivils KL, Olson LE, Iwayama T, Freeman WM, Lessard CJ, Wren JD.

BMC Bioinformatics. 2015;16 Suppl 13:S10. doi: 10.1186/1471-2105-16-S13-S10. Epub 2015 Sep 25.

44.

PDGFRα signaling drives adipose tissue fibrosis by targeting progenitor cell plasticity.

Iwayama T, Steele C, Yao L, Dozmorov MG, Karamichos D, Wren JD, Olson LE.

Genes Dev. 2015 Jun 1;29(11):1106-19. doi: 10.1101/gad.260554.115. Epub 2015 May 27.

45.

Polycomb repressive complex 2 epigenomic signature defines age-associated hypermethylation and gene expression changes.

Dozmorov MG.

Epigenetics. 2015;10(6):484-95. doi: 10.1080/15592294.2015.1040619. Epub 2015 Apr 16.

46.

Activation of the JAK/STAT pathway in Behcet's disease.

Tulunay A, Dozmorov MG, Ture-Ozdemir F, Yilmaz V, Eksioglu-Demiralp E, Alibaz-Oner F, Ozen G, Wren JD, Saruhan-Direskeneli G, Sawalha AH, Direskeneli H.

Genes Immun. 2015 Mar;16(2):176. doi: 10.1038/gene.2014.80. No abstract available.

PMID:
25739881
47.

Activation of the JAK/STAT pathway in Behcet's disease.

Tulunay A, Dozmorov MG, Ture-Ozdemir F, Yilmaz V, Eksioglu-Demiralp E, Alibaz-Oner F, Ozen G, Wren JD, Saruhan-Direskeneli G, Sawalha AH, Direskeneli H.

Genes Immun. 2015 Mar;16(2):170-5. doi: 10.1038/gene.2014.64. Epub 2014 Nov 20. Erratum in: Genes Immun. 2015 Mar;16(2):176.

48.

Proceedings of the 2014 MidSouth Computational Biology and Bioinformatics Society (MCBIOS) Conference.

Wren JD, Dozmorov MG, Burian D, Perkins A, Zhang C, Hoyt P, Kaundal R.

BMC Bioinformatics. 2014;15 Suppl 11:I1. doi: 10.1186/1471-2105-15-S11-I1. Epub 2014 Oct 21. No abstract available.

49.

Differential effects of selective frankincense (Ru Xiang) essential oil versus non-selective sandalwood (Tan Xiang) essential oil on cultured bladder cancer cells: a microarray and bioinformatics study.

Dozmorov MG, Yang Q, Wu W, Wren J, Suhail MM, Woolley CL, Young DG, Fung KM, Lin HK.

Chin Med. 2014 Jul 2;9:18. doi: 10.1186/1749-8546-9-18. eCollection 2014.

50.

Systematic classification of non-coding RNAs by epigenomic similarity.

Dozmorov MG, Giles CB, Koelsch KA, Wren JD.

BMC Bioinformatics. 2013;14 Suppl 14:S2. doi: 10.1186/1471-2105-14-S14-S2. Epub 2013 Oct 9.

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