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Items: 33

1.

High-Throughput Surface Liquid Absorption and Secretion Assays to Identify F508del CFTR Correctors Using Patient Primary Airway Epithelial Cultures.

Berg A, Hallowell S, Tibbetts M, Beasley C, Brown-Phillips T, Healy A, Pustilnik L, Doyonnas R, Pregel M.

SLAS Discov. 2019 Aug;24(7):724-737. doi: 10.1177/2472555219849375. Epub 2019 May 20.

PMID:
31107611
2.

Physiologically Relevant, Humanized Intestinal Systems to Study Metabolism and Transport of Small Molecule Therapeutics.

Sawant-Basak A, Rodrigues AD, Lech M, Doyonnas R, Kasaian M, Prasad B, Tsamandouras N.

Drug Metab Dispos. 2018 Nov;46(11):1581-1587. doi: 10.1124/dmd.118.082784. Epub 2018 Aug 20. Review.

PMID:
30126862
3.

Developing predictive assays: the phenotypic screening "rule of 3".

Vincent F, Loria P, Pregel M, Stanton R, Kitching L, Nocka K, Doyonnas R, Steppan C, Gilbert A, Schroeter T, Peakman MC.

Sci Transl Med. 2015 Jun 24;7(293):293ps15. doi: 10.1126/scitranslmed.aab1201. Review.

PMID:
26109101
4.

Targeting of 4-1BB by monoclonal antibody PF-05082566 enhances T-cell function and promotes anti-tumor activity.

Fisher TS, Kamperschroer C, Oliphant T, Love VA, Lira PD, Doyonnas R, Bergqvist S, Baxi SM, Rohner A, Shen AC, Huang C, Sokolowski SA, Sharp LL.

Cancer Immunol Immunother. 2012 Oct;61(10):1721-33. Epub 2012 Mar 11.

PMID:
22406983
5.

A single cell bioengineering approach to elucidate mechanisms of adult stem cell self-renewal.

Gilbert PM, Corbel S, Doyonnas R, Havenstrite K, Magnusson KE, Blau HM.

Integr Biol (Camb). 2012 Apr;4(4):360-7. doi: 10.1039/c2ib00148a. Epub 2012 Feb 10. Review.

6.

MicroRNA programs in normal and aberrant stem and progenitor cells.

Arnold CP, Tan R, Zhou B, Yue SB, Schaffert S, Biggs JR, Doyonnas R, Lo MC, Perry JM, Renault VM, Sacco A, Somervaille T, Viatour P, Brunet A, Cleary ML, Li L, Sage J, Zhang DE, Blau HM, Chen C, Chen CZ.

Genome Res. 2011 May;21(5):798-810. doi: 10.1101/gr.111385.110. Epub 2011 Mar 30.

7.

Perturbation of single hematopoietic stem cell fates in artificial niches.

Lutolf MP, Doyonnas R, Havenstrite K, Koleckar K, Blau HM.

Integr Biol (Camb). 2009 Jan;1(1):59-69. doi: 10.1039/b815718a. Epub 2008 Nov 21.

8.

Nuclear reprogramming in heterokaryons is rapid, extensive, and bidirectional.

Palermo A, Doyonnas R, Bhutani N, Pomerantz J, Alkan O, Blau HM.

FASEB J. 2009 May;23(5):1431-40. doi: 10.1096/fj.08-122903. Epub 2009 Jan 13.

9.

Self-renewal and expansion of single transplanted muscle stem cells.

Sacco A, Doyonnas R, Kraft P, Vitorovic S, Blau HM.

Nature. 2008 Nov 27;456(7221):502-6. doi: 10.1038/nature07384. Epub 2008 Sep 17.

10.

Extensive fusion of haematopoietic cells with Purkinje neurons in response to chronic inflammation.

Johansson CB, Youssef S, Koleckar K, Holbrook C, Doyonnas R, Corbel SY, Steinman L, Rossi FM, Blau HM.

Nat Cell Biol. 2008 May;10(5):575-83. doi: 10.1038/ncb1720. Epub 2008 Apr 20.

11.

Myoblasts and macrophages share molecular components that contribute to cell-cell fusion.

Pajcini KV, Pomerantz JH, Alkan O, Doyonnas R, Blau HM.

J Cell Biol. 2008 Mar 10;180(5):1005-19. doi: 10.1083/jcb.200707191.

12.

Hepatic parenchymal replacement in mice by transplanted allogeneic hepatocytes is facilitated by bone marrow transplantation and mediated by CD4 cells.

Streetz KL, Doyonnas R, Grimm D, Jenkins DD, Fuess S, Perryman S, Lin J, Trautwein C, Shizuru J, Blau H, Sylvester KG, Kay MA.

Hepatology. 2008 Feb;47(2):706-18. doi: 10.1002/hep.22012.

PMID:
18220289
13.

Increased host neuronal survival and motor function in BMT Parkinsonian mice: involvement of immunosuppression.

Keshet GI, Tolwani RJ, Trejo A, Kraft P, Doyonnas R, Clayberger C, Weimann JM, Blau HM.

J Comp Neurol. 2007 Oct 20;504(6):690-701.

PMID:
17722033
14.

A system for quantifying dynamic protein interactions defines a role for Herceptin in modulating ErbB2 interactions.

Wehrman TS, Raab WJ, Casipit CL, Doyonnas R, Pomerantz JH, Blau HM.

Proc Natl Acad Sci U S A. 2006 Dec 12;103(50):19063-8. Epub 2006 Dec 5.

15.

IGF-I increases bone marrow contribution to adult skeletal muscle and enhances the fusion of myelomonocytic precursors.

Sacco A, Doyonnas R, LaBarge MA, Hammer MM, Kraft P, Blau HM.

J Cell Biol. 2005 Nov 7;171(3):483-92.

16.

Bone marrow contribution to skeletal muscle: a physiological response to stress.

Palermo AT, Labarge MA, Doyonnas R, Pomerantz J, Blau HM.

Dev Biol. 2005 Mar 15;279(2):336-44.

17.

Epitope recognition of antibodies that define the sialomucin, endolyn (CD164), a negative regulator of haematopoiesis.

Jorgensen-Tye B, Levesque JP, Royle L, Doyonnas R, Chan JY, Dwek RA, Rudd PM, Harvey DJ, Simmons PJ, Watt SM.

Tissue Antigens. 2005 Mar;65(3):220-39.

PMID:
15730515
18.

Podocalyxin is a CD34-related marker of murine hematopoietic stem cells and embryonic erythroid cells.

Doyonnas R, Nielsen JS, Chelliah S, Drew E, Hara T, Miyajima A, McNagny KM.

Blood. 2005 Jun 1;105(11):4170-8. Epub 2005 Feb 8.

PMID:
15701716
19.

Hematopoietic contribution to skeletal muscle regeneration by myelomonocytic precursors.

Doyonnas R, LaBarge MA, Sacco A, Charlton C, Blau HM.

Proc Natl Acad Sci U S A. 2004 Sep 14;101(37):13507-12. Epub 2004 Sep 7.

20.

Activation/division of lymphocytes results in increased levels of cytoplasmic activation/proliferation-associated protein-1: prototype of a new family of proteins.

Grill B, Wilson GM, Zhang KX, Wang B, Doyonnas R, Quadroni M, Schrader JW.

J Immunol. 2004 Feb 15;172(4):2389-400.

21.

CD34 is a specific marker of mature murine mast cells.

Drew E, Merkens H, Chelliah S, Doyonnas R, McNagny KM.

Exp Hematol. 2002 Oct;30(10):1211-8.

PMID:
12384153
22.

Avian models to study the transcriptional control of hematopoietic lineage commitment and to identify lineage-specific genes.

Nielsen JS, Doyonnas R, McNagny KM.

Cells Tissues Organs. 2002;171(1):44-63. Review.

PMID:
12021491
23.

Homophilic adhesion of human CEACAM1 involves N-terminal domain interactions: structural analysis of the binding site.

Watt SM, Teixeira AM, Zhou GQ, Doyonnas R, Zhang Y, Grunert F, Blumberg RS, Kuroki M, Skubitz KM, Bates PA.

Blood. 2001 Sep 1;98(5):1469-79.

PMID:
11520797
24.

Anuria, omphalocele, and perinatal lethality in mice lacking the CD34-related protein podocalyxin.

Doyonnas R, Kershaw DB, Duhme C, Merkens H, Chelliah S, Graf T, McNagny KM.

J Exp Med. 2001 Jul 2;194(1):13-27.

25.

Relationship between novel isoforms, functionally important domains, and subcellular distribution of CD164/endolyn.

Chan JY, Lee-Prudhoe JE, Jorgensen B, Ihrke G, Doyonnas R, Zannettino AC, Buckle VJ, Ward CJ, Simmons PJ, Watt SM.

J Biol Chem. 2001 Jan 19;276(3):2139-52. Epub 2000 Oct 10.

26.

CD164 monoclonal antibodies that block hemopoietic progenitor cell adhesion and proliferation interact with the first mucin domain of the CD164 receptor.

Doyonnas R, Yi-Hsin Chan J, Butler LH, Rappold I, Lee-Prudhoe JE, Zannettino AC, Simmons PJ, Bühring HJ, Levesque JP, Watt SM.

J Immunol. 2000 Jul 15;165(2):840-51.

27.

Functionally defined CD164 epitopes are expressed on CD34(+) cells throughout ontogeny but display distinct distribution patterns in adult hematopoietic and nonhematopoietic tissues.

Watt SM, Butler LH, Tavian M, Bühring HJ, Rappold I, Simmons PJ, Zannettino AC, Buck D, Fuchs A, Doyonnas R, Chan JY, Levesque JP, Peault B, Roxanis I.

Blood. 2000 May 15;95(10):3113-24.

PMID:
10807777
28.

CD164, a novel sialomucin on CD34(+) and erythroid subsets, is located on human chromosome 6q21.

Watt SM, Bühring HJ, Rappold I, Chan JY, Lee-Prudhoe J, Jones T, Zannettino AC, Simmons PJ, Doyonnas R, Sheer D, Butler LH.

Blood. 1998 Aug 1;92(3):849-66.

PMID:
9680353
29.

The N-domain of the human CD66a adhesion molecule is a target for Opa proteins of Neisseria meningitidis and Neisseria gonorrhoeae.

Virji M, Watt SM, Barker S, Makepeace K, Doyonnas R.

Mol Microbiol. 1996 Dec;22(5):929-39.

PMID:
8971714
30.

Identification of alpha v beta 3 as a heterotypic ligand for CD31/PECAM-1.

Buckley CD, Doyonnas R, Newton JP, Blystone SD, Brown EJ, Watt SM, Simmons DL.

J Cell Sci. 1996 Feb;109 ( Pt 2):437-45.

31.

The identification and characterization of a novel human differentiation-inhibiting protein that selectively blocks erythroid differentiation.

Durkin JP, Biquard JM, Whitfield JF, Morardet N, Royer J, Macdonald P, Tremblay R, Legal JD, Doyonnas R, Blanchet JP, et al.

Blood. 1992 Mar 1;79(5):1161-71.

PMID:
1536943
32.

Characterization of a novel erythropoiesis-inhibiting human protein.

Durkin JP, Biquard JM, Blanchet JP, Whitfield JF, Doyonnas R, MacDonald P, Morardet N, Royer J, Tremblay R, Krsmanovic V.

Ann N Y Acad Sci. 1991;628:233-40.

PMID:
1906252
33.

The cytotoxicity of Pseudomonas exotoxin A, inactivated by modification of the cell-binding domain I, is restored when conjugated to an erythroid cell-specific targeting agent.

Bourdenet S, Doyonnas R, Vacheron MJ, Guinand M, Fasciotto B, Ristic A, Michel G, Cozzone AJ, Durkin JP, Whitfield JF, et al.

Cancer Lett. 1990 Apr 20;50(2):121-7.

PMID:
2109650

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