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Items: 47

1.

BioStruct-Africa: empowering Africa-based scientists through structural biology knowledge transfer and mentoring - recent advances and future perspectives.

Nji E, Traore DAK, Ndi M, Joko CA, Doyle DA.

J Synchrotron Radiat. 2019 Sep 1;26(Pt 5):1843-1850. doi: 10.1107/S1600577519008981. Epub 2019 Aug 28.

PMID:
31490179
2.

Investigation of feeding behaviour in C. elegans reveals distinct pharmacological and antibacterial effects of nicotine.

Kudelska MM, Lewis A, Ng CT, Doyle DA, Holden-Dye L, O'Connor VM, Walker RJ.

Invert Neurosci. 2018 Nov 7;18(4):14. doi: 10.1007/s10158-018-0219-1.

PMID:
30406344
3.

The N-acyltransferase Lnt: Structure-function insights from recent simultaneous studies.

Cheng W, Doyle DA, El Arnaout T.

Int J Biol Macromol. 2018 Oct 1;117:870-877. doi: 10.1016/j.ijbiomac.2018.05.229. Epub 2018 May 31. Review.

PMID:
29859843
4.

Efflux drug transporters at the forefront of antimicrobial resistance.

Rahman T, Yarnall B, Doyle DA.

Eur Biophys J. 2017 Oct;46(7):647-653. doi: 10.1007/s00249-017-1238-2. Epub 2017 Jul 14. Review.

5.

Concentration-dependent effects of acute and chronic neonicotinoid exposure on the behaviour and development of the nematode Caenorhabditis elegans.

Kudelska MM, Holden-Dye L, O'Connor V, Doyle DA.

Pest Manag Sci. 2017 Jul;73(7):1345-1351. doi: 10.1002/ps.4564. Epub 2017 May 9.

PMID:
28261957
6.

Idiopathic infantile hypercalcemia: case report and review of the literature.

Marks BE, Doyle DA.

J Pediatr Endocrinol Metab. 2016 Feb;29(2):127-32. doi: 10.1515/jpem-2015-0133. Review.

PMID:
26501157
7.

MCPIP1 Regulates Fibroblast Migration in 3-D Collagen Matrices Downstream of MAP Kinases and NF-κB.

Chao J, Dai X, Peña T, Doyle DA, Guenther TM, Carlson MA.

J Invest Dermatol. 2015 Dec;135(12):2944-2954. doi: 10.1038/jid.2015.334. Epub 2015 Aug 26.

8.

Cloning, expression, purification, crystallization and preliminary X-ray diffraction of a lysine-specific permease from Pseudomonas aeruginosa.

Nji E, Li D, Doyle DA, Caffrey M.

Acta Crystallogr F Struct Biol Commun. 2014 Oct;70(Pt 10):1362-7. doi: 10.1107/S2053230X14017865. Epub 2014 Sep 25.

9.

Expression of green fluorescent protein in human foreskin fibroblasts for use in 2D and 3D culture models.

Chao J, Peña T, Heimann DG, Hansen C, Doyle DA, Yanala UR, Guenther TM, Carlson MA.

Wound Repair Regen. 2014 Jan-Feb;22(1):134-40. doi: 10.1111/wrr.12121.

PMID:
24393161
10.

Heterologous expression and purification of an active human TRPV3 ion channel.

Kol S, Braun C, Thiel G, Doyle DA, Sundström M, Gourdon P, Nissen P.

FEBS J. 2013 Dec;280(23):6010-21. doi: 10.1111/febs.12520. Epub 2013 Sep 30.

11.

Dual-mode phospholipid regulation of human inward rectifying potassium channels.

Cheng WWL, D'Avanzo N, Doyle DA, Nichols CG.

Biophys J. 2011 Feb 2;100(3):620-628. doi: 10.1016/j.bpj.2010.12.3724.

12.

Direct and specific activation of human inward rectifier K+ channels by membrane phosphatidylinositol 4,5-bisphosphate.

D'Avanzo N, Cheng WW, Doyle DA, Nichols CG.

J Biol Chem. 2010 Nov 26;285(48):37129-32. doi: 10.1074/jbc.C110.186692. Epub 2010 Oct 4.

13.

Unusual binding interactions in PDZ domain crystal structures help explain binding mechanisms.

Elkins JM, Gileadi C, Shrestha L, Phillips C, Wang J, Muniz JR, Doyle DA.

Protein Sci. 2010 Apr;19(4):731-41. doi: 10.1002/pro.349.

14.

Expression and purification of recombinant human inward rectifier K+ (KCNJ) channels in Saccharomyces cerevisiae.

D'Avanzo N, Cheng WW, Xia X, Dong L, Savitsky P, Nichols CG, Doyle DA.

Protein Expr Purif. 2010 May;71(1):115-21. doi: 10.1016/j.pep.2010.01.010. Epub 2010 Jan 11.

15.

Membranes: editorial overview.

Doyle DA, Shipley GG.

Curr Opin Struct Biol. 2009 Aug;19(4):369-71. doi: 10.1016/j.sbi.2009.07.011. Epub 2009 Aug 24. No abstract available.

PMID:
19709877
16.

Regulator of G-protein signaling 14 (RGS14) is a selective H-Ras effector.

Willard FS, Willard MD, Kimple AJ, Soundararajan M, Oestreich EA, Li X, Sowa NA, Kimple RJ, Doyle DA, Der CJ, Zylka MJ, Snider WD, Siderovski DP.

PLoS One. 2009;4(3):e4884. doi: 10.1371/journal.pone.0004884. Epub 2009 Mar 25.

17.

Structural diversity in the RGS domain and its interaction with heterotrimeric G protein alpha-subunits.

Soundararajan M, Willard FS, Kimple AJ, Turnbull AP, Ball LJ, Schoch GA, Gileadi C, Fedorov OY, Dowler EF, Higman VA, Hutsell SQ, Sundström M, Doyle DA, Siderovski DP.

Proc Natl Acad Sci U S A. 2008 Apr 29;105(17):6457-62. doi: 10.1073/pnas.0801508105. Epub 2008 Apr 23.

18.

Molecular aspects, clinical aspects and possible treatment modalities for Costello syndrome: Proceedings from the 1st International Costello Syndrome Research Symposium 2007.

Rauen KA, Hefner E, Carrillo K, Taylor J, Messier L, Aoki Y, Gripp KW, Matsubara Y, Proud VK, Hammond P, Allanson JE, Delrue MA, Axelrad ME, Lin AE, Doyle DA, Kerr B, Carey JC, McCormick F, Silva AJ, Kieran MW, Hinek A, Nguyen TT, Schoyer L.

Am J Med Genet A. 2008 May 1;146A(9):1205-17. doi: 10.1002/ajmg.a.32276. No abstract available.

PMID:
18412122
19.

RhoB can adopt a Mg2+ free conformation prior to GEF binding.

Soundararajan M, Turnbull A, Fedorov O, Johansson C, Doyle DA.

Proteins. 2008 Jul;72(1):498-505. doi: 10.1002/prot.22017. No abstract available.

PMID:
18393397
20.

The scientific impact of the Structural Genomics Consortium: a protein family and ligand-centered approach to medically-relevant human proteins.

Gileadi O, Knapp S, Lee WH, Marsden BD, Müller S, Niesen FH, Kavanagh KL, Ball LJ, von Delft F, Doyle DA, Oppermann UC, Sundström M.

J Struct Funct Genomics. 2007 Sep;8(2-3):107-19. Epub 2007 Oct 12. Review.

21.

Structure of PICK1 and other PDZ domains obtained with the help of self-binding C-terminal extensions.

Elkins JM, Papagrigoriou E, Berridge G, Yang X, Phillips C, Gileadi C, Savitsky P, Doyle DA.

Protein Sci. 2007 Apr;16(4):683-94.

22.

Structural basis for protein-protein interactions in the 14-3-3 protein family.

Yang X, Lee WH, Sobott F, Papagrigoriou E, Robinson CV, Grossmann JG, Sundström M, Doyle DA, Elkins JM.

Proc Natl Acad Sci U S A. 2006 Nov 14;103(46):17237-42. Epub 2006 Nov 3.

23.

The centaurin gamma-1 GTPase-like domain functions as an NTPase.

Soundararajan M, Yang X, Elkins JM, Sobott F, Doyle DA.

Biochem J. 2007 Feb 1;401(3):679-88.

24.

Phospholipid requirement and pH optimum for the in vitro enzymatic activity of the E. coli P-type ATPase ZntA.

Zimmer J, Doyle DA.

Biochim Biophys Acta. 2006 May;1758(5):645-52. Epub 2006 Apr 21.

25.

Crystal structure of the CorA Mg2+ transporter.

Lunin VV, Dobrovetsky E, Khutoreskaya G, Zhang R, Joachimiak A, Doyle DA, Bochkarev A, Maguire ME, Edwards AM, Koth CM.

Nature. 2006 Apr 6;440(7085):833-7.

26.

Structural characterization and pH-induced conformational transition of full-length KcsA.

Zimmer J, Doyle DA, Grossmann JG.

Biophys J. 2006 Mar 1;90(5):1752-66. Epub 2005 Dec 9.

27.

Two different conformational states of the KirBac3.1 potassium channel revealed by electron crystallography.

Kuo A, Domene C, Johnson LN, Doyle DA, Vénien-Bryan C.

Structure. 2005 Oct;13(10):1463-72.

28.

Role of aromatic localization in the gating process of a potassium channel.

Domene C, Vemparala S, Klein ML, Vénien-Bryan C, Doyle DA.

Biophys J. 2006 Jan 1;90(1):L01-3. Epub 2005 Sep 16.

29.

Modeling of an ion channel in its open conformation.

Domene C, Doyle DA, Vénien-Bryan C.

Biophys J. 2005 Jul;89(1):L01-3.

30.

Transmembrane helix prediction: a comparative evaluation and analysis.

Cuthbertson JM, Doyle DA, Sansom MS.

Protein Eng Des Sel. 2005 Jun;18(6):295-308. Epub 2005 Jun 2.

PMID:
15932905
31.

Molecular insights into ion channel function (Review).

Doyle DA.

Mol Membr Biol. 2004 Jul-Aug;21(4):221-5. Review.

PMID:
15371011
32.

Potassium channel structures: do they conform?

Gulbis JM, Doyle DA.

Curr Opin Struct Biol. 2004 Aug;14(4):440-6. Review.

PMID:
15313238
33.
34.

Structural changes during ion channel gating.

Doyle DA.

Trends Neurosci. 2004 Jun;27(6):298-302. Review.

PMID:
15165732
35.

Structural themes in ion channels.

Doyle DA.

Eur Biophys J. 2004 May;33(3):175-9. Epub 2004 Mar 16. Review.

PMID:
15024522
36.

Crystal structure of the potassium channel KirBac1.1 in the closed state.

Kuo A, Gulbis JM, Antcliff JF, Rahman T, Lowe ED, Zimmer J, Cuthbertson J, Ashcroft FM, Ezaki T, Doyle DA.

Science. 2003 Jun 20;300(5627):1922-6. Epub 2003 May 8.

37.

Increasing the diffraction limit and internal order of a membrane protein crystal by dehydration.

Kuo A, Bowler MW, Zimmer J, Antcliff JF, Doyle DA.

J Struct Biol. 2003 Feb;141(2):97-102.

PMID:
12615535
38.

Growth hormone treatment and pseudotumor cerebri: coincidence or close relationship?

Reeves GD, Doyle DA.

J Pediatr Endocrinol Metab. 2002 May;15 Suppl 2:723-30.

PMID:
12092686
39.

Leydig-cell tumors caused by an activating mutation of the gene encoding the luteinizing hormone receptor.

Liu G, Duranteau L, Carel JC, Monroe J, Doyle DA, Shenker A.

N Engl J Med. 1999 Dec 2;341(23):1731-6. No abstract available.

41.

The structure of the potassium channel: molecular basis of K+ conduction and selectivity.

Doyle DA, Morais Cabral J, Pfuetzner RA, Kuo A, Gulbis JM, Cohen SL, Chait BT, MacKinnon R.

Science. 1998 Apr 3;280(5360):69-77.

42.

Prokaryotes offer hope for potassium channel structural studies.

MacKinnon R, Doyle DA.

Nat Struct Biol. 1997 Nov;4(11):877-9. No abstract available.

PMID:
9360597
43.

Crystal structure of the gramicidin/potassium thiocyanate complex.

Doyle DA, Wallace BA.

J Mol Biol. 1997 Mar 14;266(5):963-77.

PMID:
9086274
44.
45.

Caesium-binding sites in the gramicidin pore.

Doyle DA, Wallace BA.

Biochem Soc Trans. 1994 Nov;22(4):1043-5. No abstract available.

PMID:
7535256
46.

Protocol for measuring the relative toxicity of substance of plant foliage.

Thompson CR, Kats G, Dawson PW, Doyle DA.

Bull Environ Contam Toxicol. 1981 Feb;26(2):281-7. No abstract available.

PMID:
7248554
47.

o,p'--DDD and adrenal carcinoma.

McKiernan P, Doyle DA, Duffy GJ, Towers RP, Duff FA, O'Donovan DK.

Ir J Med Sci. 1978 Dec;147(12):437-40. No abstract available.

PMID:
730493

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