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Items: 1 to 50 of 71

1.

Intramammary Angiomatoid Fibrous Histiocytoma, a Rare EWSR1 Rearranged Mesenchymal Neoplasm in a Previously Unreported Anatomic Location with Review of the Cleveland Clinic Experience.

Bruehl FK, Cooper KL, Kilpatrick SE, Weindel MD, Ganea M, Astbury C, Downs-Kelly EP, Sturgis CD.

Case Rep Pathol. 2019 May 20;2019:9012878. doi: 10.1155/2019/9012878. eCollection 2019.

2.

Cystic neutrophilic granulomatous mastitis: The Cleveland Clinic experience with diagnosis and management.

Gautham I, Radford DM, Kovacs CS, Calhoun BC, Procop GW, Shepardson LB, Dawson AE, Downs-Kelly EP, Zhang GX, Al-Hilli Z, Fanning AA, Wilson DA, Sturgis CD.

Breast J. 2019 Jan;25(1):80-85. doi: 10.1111/tbj.13160. Epub 2018 Nov 17.

PMID:
30449049
3.

Elevated Tryptase in EoE Is an Independent Phenomenon Associated with Extra-Esophageal Symptoms.

Kutty GR, Downs-Kelly E, Crispin HT, Peterson KA.

Dig Dis Sci. 2019 Jan;64(1):152-157. doi: 10.1007/s10620-018-5298-7. Epub 2018 Sep 28.

PMID:
30267171
4.

Secretory breast carcinoma in an 8-year-old girl: A case report and literature review.

Garlick JW, Olson KA, Downs-Kelly E, Bucher BT, Matsen CB.

Breast J. 2018 Nov;24(6):1055-1061. doi: 10.1111/tbj.13126. Epub 2018 Sep 24.

PMID:
30251458
5.

Expression of LC3B and FIP200/Atg17 in brain metastases of breast cancer.

Hashemi-Sadraei N, Müller-Greven GM, Abdul-Karim FW, Ulasov I, Downs-Kelly E, Burgett ME, Lauko A, Qadan MA, Weil RJ, Ahluwalia MS, Du L, Prayson RA, Chao ST, Budd TG, Barnholtz-Sloan J, Nowacki AS, Keri RA, Gladson CL.

J Neurooncol. 2018 Nov;140(2):237-248. doi: 10.1007/s11060-018-2959-5. Epub 2018 Aug 9.

PMID:
30094720
6.

Unmasking Early Wild-Type Transthyretin Amyloidosis Cardiomyopathy in a Patient With Refractory Atrial Fibrillation and Unremarkable Cardiac Imaging.

Varedi D, Kovacsovics T, Downs Kelly E, Abraham J, Cowley J, Barrell K, Revelo MP, Stehlik J, Drakos S, Marrouche N, Wilson B, Swanson EA, Fang J, Nativi-Nicolau J.

Circ Heart Fail. 2018 Jul;11(7):e004812. doi: 10.1161/CIRCHEARTFAILURE.117.004812. No abstract available.

PMID:
29921704
7.

Pulmonary Mycobacterial Spindle Cell Pseudotumor: A Report of 3 Cases Including a Practical Approach to Histopathologic Recognition of This Unusual Entity.

Boylan KE, Larsen BT, Young BA, Downs-Kelly E, Panchabhai TS, Collum ES, Jensen L, Emerson LL.

Int J Surg Pathol. 2018 Oct;26(7):629-634. doi: 10.1177/1066896918770010. Epub 2018 May 2.

PMID:
29720005
8.

Reply to Commentary on 'HER2 immunohistochemical and fluorescence in situ hybridization discordances in invasive breast carcinoma with micropapillary features'.

Stewart RL, Gulbahce EH, Geiersbach KB, Downs-Kelly E.

Mod Pathol. 2018 Apr;31(4):686. doi: 10.1038/modpathol.2018.28. No abstract available.

9.

Intramucosal lipomas of the colon implicate Cowden syndrome.

Caliskan A, Kohlmann WK, Affolter KE, Downs-Kelly E, Kanth P, Bronner MP.

Mod Pathol. 2018 Apr;31(4):643-651. doi: 10.1038/modpathol.2017.161. Epub 2017 Dec 1.

10.

Primary Cystic Pleuropulmonary Synovial Sarcoma Presenting as Recurrent Pneumothorax.

Johnson ED, Downs-Kelly E, Bull DA, Gulbahce HE.

Case Rep Oncol. 2017 Jul 14;10(2):660-665. doi: 10.1159/000478845. eCollection 2017 May-Aug.

11.

HER2 immunohistochemical and fluorescence in situ hybridization discordances in invasive breast carcinoma with micropapillary features.

Stewart RL, Caron JE, Gulbahce EH, Factor RE, Geiersbach KB, Downs-Kelly E.

Mod Pathol. 2017 Nov;30(11):1561-1566. doi: 10.1038/modpathol.2017.65. Epub 2017 Jul 28.

12.

A Clinicopathologic Evaluation of Incidental Fundic Gland Polyps With Dysplasia: Implications for Clinical Management.

Lloyd IE, Kohlmann WK, Gligorich K, Hall A, Lyon E, Downs-Kelly E, Samowitz WS, Bronner MP.

Am J Gastroenterol. 2017 Jul;112(7):1094-1102. doi: 10.1038/ajg.2017.125. Epub 2017 May 2.

PMID:
28462913
13.

Impact of an alternative chromosome 17 probe and the 2013 American Society of Clinical Oncology and College of American Pathologists guidelines on fluorescence in situ hybridization for the determination of HER2 gene amplification in breast cancer.

Donaldson AR, Shetty S, Wang Z, Rivera CL, Portier BP, Budd GT, Downs-Kelly E, Lanigan CP, Calhoun BC.

Cancer. 2017 Jun 15;123(12):2230-2239. doi: 10.1002/cncr.30592. Epub 2017 Feb 13.

14.

Radiation-associated angiosarcoma in the setting of breast cancer mimicking radiation dermatitis: A diagnostic pitfall.

Daniels BH, Ko JS, Rowe JJ, Downs-Kelly E, Billings SD.

J Cutan Pathol. 2017 May;44(5):456-461. doi: 10.1111/cup.12917. Epub 2017 Feb 21.

PMID:
28169467
15.

RAI1 Alternate Probe Identifies Additional Breast Cancer Cases as Amplified Following Equivocal HER2 Fluorescence In Situ Hybridization Testing: Experience From a National Reference Laboratory.

Hui L, Geiersbach KB, Downs-Kelly E, Gulbahce HE.

Arch Pathol Lab Med. 2017 Feb;141(2):274-278. doi: 10.5858/arpa.2016-0201-OA. Epub 2016 Dec 13.

PMID:
27959582
16.

Lobular neoplasia diagnosed on breast Core biopsy: frequency of carcinoma on excision and implications for management.

Calhoun BC, Collie AM, Lott-Limbach AA, Udoji EN, Sieck LR, Booth CN, Downs-Kelly E.

Ann Diagn Pathol. 2016 Dec;25:20-25. doi: 10.1016/j.anndiagpath.2016.07.009. Epub 2016 Aug 18.

PMID:
27806840
17.

Inconsistent Results With Different Secondary Reflex Assays for Resolving HER2 Status.

Willmore-Payne C, Damjanovich-Colmenares K, Pasi AV, Werner TL, Gulbahce HE, Downs-Kelly E, Geiersbach KB.

Am J Clin Pathol. 2016 Nov 1;146(5):618-626. doi: 10.1093/ajcp/aqw177.

PMID:
27773872
18.

Automated Bright-Field Dual-Color In Situ Hybridization for MDM2: Interobserver Reproducibility and Correlation With Fluorescence In Situ Hybridization in a Series of Soft Tissue Consults.

Zhang G, Lanigan CP, Goldblum JR, Tubbs RR, Downs-Kelly E.

Arch Pathol Lab Med. 2016 Oct;140(10):1111-5. doi: 10.5858/arpa.2015-0249-OA.

PMID:
27684983
19.

Genomic Copy Number Analysis of HER2-Equivocal Breast Cancers.

Geiersbach KB, Willmore-Payne C, Pasi AV, Paxton CN, Werner TL, Xu X, Wittwer CT, Gulbahce HE, Downs-Kelly E.

Am J Clin Pathol. 2016 Oct;146(4):439-47. doi: 10.1093/ajcp/aqw130. Epub 2016 Sep 10.

PMID:
27614666
20.

Mesenteric Arteriovenous Dysplasia/Vasculopathy Is Distinct From Fibromuscular Dysplasia.

Patil DT, Kissiedu J, Rodriguez ER, Downs-Kelly E, Liu X, Rybicki LA, Tan CD.

Am J Surg Pathol. 2016 Oct;40(10):1316-25. doi: 10.1097/PAS.0000000000000710.

PMID:
27487739
21.

HER2 Immunohistochemistry-Guided Targeted Fluorescence In Situ Hybridization Analysis Does Not Help Identify Intratumoral Heterogeneity in Breast Cancer.

Gulbahce HE, Factor R, Geiersbach K, Downs-Kelly E.

Arch Pathol Lab Med. 2016 Aug;140(8):741. doi: 10.5858/arpa.2016-0015-LE. No abstract available.

PMID:
27472230
22.

Targeted Vaccination against Human α-Lactalbumin for Immunotherapy and Primary Immunoprevention of Triple Negative Breast Cancer.

Tuohy VK, Jaini R, Johnson JM, Loya MG, Wilk D, Downs-Kelly E, Mazumder S.

Cancers (Basel). 2016 Jun 16;8(6). pii: E56. doi: 10.3390/cancers8060056.

23.

Expression of the MHC Class II Pathway in Triple-Negative Breast Cancer Tumor Cells Is Associated with a Good Prognosis and Infiltrating Lymphocytes.

Forero A, Li Y, Chen D, Grizzle WE, Updike KL, Merz ND, Downs-Kelly E, Burwell TC, Vaklavas C, Buchsbaum DJ, Myers RM, LoBuglio AF, Varley KE.

Cancer Immunol Res. 2016 May;4(5):390-9. doi: 10.1158/2326-6066.CIR-15-0243. Epub 2016 Mar 15.

24.

Eosinophilic Esophagitis in Two Patients with Systemic Sclerosis.

Frech TM, Boynton K, Downs-Kelly E, Jones B, Kriesel JD, Peterson K.

Case Rep Rheumatol. 2016;2016:6410421. doi: 10.1155/2016/6410421. Epub 2016 Jan 20.

25.

Digitally guided microdissection aids somatic mutation detection in difficult to dissect tumors.

Geiersbach K, Adey N, Welker N, Elsberry D, Malmberg E, Edwards S, Downs-Kelly E, Salama M, Bronner M.

Cancer Genet. 2016 Jan-Feb;209(1-2):42-9. doi: 10.1016/j.cancergen.2015.12.004. Epub 2015 Dec 15.

26.

Reproducibility of residual cancer burden for prognostic assessment of breast cancer after neoadjuvant chemotherapy.

Peintinger F, Sinn B, Hatzis C, Albarracin C, Downs-Kelly E, Morkowski J, Gould R, Symmans WF.

Mod Pathol. 2015 Jul;28(7):913-20. doi: 10.1038/modpathol.2015.53. Epub 2015 May 1.

27.

Margins: a status report from the Annual Meeting of the American Society of Breast Surgeons.

Harness JK, Giuliano AE, Pockaj BA, Downs-Kelly E.

Ann Surg Oncol. 2014 Oct;21(10):3192-7. doi: 10.1245/s10434-014-3957-2. Epub 2014 Aug 1.

PMID:
25081342
28.

Reliability of PAX8 in clinical practice to accurately determine primary site of origin in female pelvic or abdominal lesions.

Roma AA, Downs-Kelly E.

Ann Diagn Pathol. 2014 Aug;18(4):227-31. doi: 10.1016/j.anndiagpath.2014.04.001. Epub 2014 Apr 13.

PMID:
24857336
29.

Kindlin-3 enhances breast cancer progression and metastasis by activating Twist-mediated angiogenesis.

Sossey-Alaoui K, Pluskota E, Davuluri G, Bialkowska K, Das M, Szpak D, Lindner DJ, Downs-Kelly E, Thompson CL, Plow EF.

FASEB J. 2014 May;28(5):2260-71. doi: 10.1096/fj.13-244004. Epub 2014 Jan 27.

30.

Serrated lesions of the appendix frequently harbor KRAS mutations and not BRAF mutations indicating a distinctly different serrated neoplastic pathway in the appendix.

Pai RK, Hartman DJ, Gonzalo DH, Lai KK, Downs-Kelly E, Goldblum JR, Liu X, Patil DT, Bennett AE, Plesec TP, Kuan SF, Nikiforova MN, Shadrach B, Pai RK.

Hum Pathol. 2014 Feb;45(2):227-35. doi: 10.1016/j.humpath.2013.10.021. Epub 2013 Oct 30.

PMID:
24439221
31.

HER4 expression status correlates with improved outcome in both neoadjuvant and adjuvant Trastuzumab treated invasive breast carcinoma.

Portier BP, Minca EC, Wang Z, Lanigan C, Gruver AM, Downs-Kelly E, Budd GT, Tubbs RR.

Oncotarget. 2013 Oct;4(10):1662-72.

32.

Gene expression profiling of serrated polyps identifies annexin A10 as a marker of a sessile serrated adenoma/polyp.

Gonzalo DH, Lai KK, Shadrach B, Goldblum JR, Bennett AE, Downs-Kelly E, Liu X, Henricks W, Patil DT, Carver P, Na J, Gopalan B, Rybicki L, Pai RK.

J Pathol. 2013 Aug;230(4):420-9. doi: 10.1002/path.4200.

PMID:
23595865
33.

Reproducibility of the villous component and high-grade dysplasia in colorectal adenomas <1 cm: implications for endoscopic surveillance.

Mahajan D, Downs-Kelly E, Liu X, Pai RK, Patil DT, Rybicki L, Bennett AE, Plesec T, Cummings O, Rex D, Goldblum JR.

Am J Surg Pathol. 2013 Mar;37(3):427-33. doi: 10.1097/PAS.0b013e31826cf50f.

PMID:
23348206
34.

Delay to formalin fixation 'cold ischemia time': effect on ERBB2 detection by in-situ hybridization and immunohistochemistry.

Portier BP, Wang Z, Downs-Kelly E, Rowe JJ, Patil D, Lanigan C, Budd GT, Hicks DG, Rimm DL, Tubbs RR.

Mod Pathol. 2013 Jan;26(1):1-9. doi: 10.1038/modpathol.2012.123. Epub 2012 Aug 17.

35.

Isospora belli superinfection in a patient with eosinophilic gastroenteritis--a diagnostic challenge.

Navaneethan U, Venkatesh PG, Downs-Kelly E, Shen B.

J Crohns Colitis. 2012 Mar;6(2):236-9. doi: 10.1016/j.crohns.2011.08.010. Epub 2011 Sep 16.

PMID:
22325178
36.

Prediction of adenocarcinoma in esophagectomy specimens based upon analysis of preresection biopsies of Barrett esophagus with at least high-grade dysplasia: a comparison of 2 systems.

Patil DT, Goldblum JR, Rybicki L, Plesec TP, Mendelin JE, Bennett AE, Castilla EA, Henricks WH, Schoenfield L, Skacel M, Yerian LM, Rice TW, Bronner MP, Downs-Kelly E.

Am J Surg Pathol. 2012 Jan;36(1):134-41. doi: 10.1097/PAS.0b013e3182354e43.

PMID:
22067333
37.

Esophageal carcinoma cuniculatum: report of 9 cases.

Landau M, Goldblum JR, DeRoche T, Dumot J, Downs-Kelly E, Rice TW, Xiao SY, Liu X.

Am J Surg Pathol. 2012 Jan;36(1):8-17. doi: 10.1097/PAS.0b013e3182348aa1.

PMID:
22020041
38.

G1P3, an interferon- and estrogen-induced survival protein contributes to hyperplasia, tamoxifen resistance and poor outcomes in breast cancer.

Cheriyath V, Kuhns MA, Jacobs BS, Evangelista P, Elson P, Downs-Kelly E, Tubbs R, Borden EC.

Oncogene. 2012 Apr 26;31(17):2222-36. doi: 10.1038/onc.2011.393. Epub 2011 Sep 26.

PMID:
21996729
39.

Lynch syndrome screening in newly diagnosed colorectal cancer in general pathology practice: from the revised Bethesda guidelines to a universal approach.

Morrison J, Bronner M, Leach BH, Downs-Kelly E, Goldblum JR, Liu X.

Scand J Gastroenterol. 2011 Nov;46(11):1340-8. doi: 10.3109/00365521.2011.610003. Epub 2011 Aug 31.

PMID:
21879804
40.

Leptin deficiency suppresses MMTV-Wnt-1 mammary tumor growth in obese mice and abrogates tumor initiating cell survival.

Zheng Q, Dunlap SM, Zhu J, Downs-Kelly E, Rich J, Hursting SD, Berger NA, Reizes O.

Endocr Relat Cancer. 2011 Jul 11;18(4):491-503. doi: 10.1530/ERC-11-0102. Print 2011 Aug. Erratum in: Endocr Relat Cancer. 2011 Oct;18(5):X1.

41.

Clinical implications of margin involvement by pleomorphic lobular carcinoma in situ.

Downs-Kelly E, Bell D, Perkins GH, Sneige N, Middleton LP.

Arch Pathol Lab Med. 2011 Jun;135(6):737-43. doi: 10.1043/2010-0204-OA.1.

PMID:
21631266
42.

Gastrointestinal stromal tumors: molecular mechanisms and targeted therapies.

Downs-Kelly E, Rubin BP.

Patholog Res Int. 2011 Apr 14;2011:708596. doi: 10.4061/2011/708596.

43.

Specific kinesin expression profiles associated with taxane resistance in basal-like breast cancer.

Tan MH, De S, Bebek G, Orloff MS, Wesolowski R, Downs-Kelly E, Budd GT, Stark GR, Eng C.

Breast Cancer Res Treat. 2012 Feb;131(3):849-58. doi: 10.1007/s10549-011-1500-8. Epub 2011 Apr 9.

44.

FUS (16p11) gene rearrangement as detected by fluorescence in-situ hybridization in cutaneous low-grade fibromyxoid sarcoma: a potential diagnostic tool.

Patel RM, Downs-Kelly E, Dandekar MN, Fanburg-Smith JC, Billings SD, Tubbs RR, Goldblum JR.

Am J Dermatopathol. 2011 Apr;33(2):140-3. doi: 10.1097/IAE.0b013e318176de80.

PMID:
21399449
45.

Utilization of fluorescence in situ hybridization in the diagnosis of 230 mesenchymal neoplasms: an institutional experience.

Tanas MR, Rubin BP, Tubbs RR, Billings SD, Downs-Kelly E, Goldblum JR.

Arch Pathol Lab Med. 2010 Dec;134(12):1797-803. doi: 10.1043/2009-0571-OAR.1.

PMID:
21128778
46.

WAVE3, an actin remodeling protein, is regulated by the metastasis suppressor microRNA, miR-31, during the invasion-metastasis cascade.

Sossey-Alaoui K, Downs-Kelly E, Das M, Izem L, Tubbs R, Plow EF.

Int J Cancer. 2011 Sep 15;129(6):1331-43. doi: 10.1002/ijc.25793. Epub 2011 Mar 22.

47.

Silver in situ hybridization (SISH) for determination of HER2 gene status in breast carcinoma: comparison with FISH and assessment of interobserver reproducibility.

Papouchado BG, Myles J, Lloyd RV, Stoler M, Oliveira AM, Downs-Kelly E, Morey A, Bilous M, Nagle R, Prescott N, Wang L, Dragovich L, McElhinny A, Garcia CF, Ranger-Moore J, Free H, Powell W, Loftus M, Pettay J, Gaire F, Roberts C, Dietel M, Roche P, Grogan T, Tubbs R.

Am J Surg Pathol. 2010 Jun;34(6):767-76. doi: 10.1097/PAS.0b013e3181d96231.

PMID:
20421783
48.

Genome-wide transcriptome analyses reveal p53 inactivation mediated loss of miR-34a expression in malignant peripheral nerve sheath tumours.

Subramanian S, Thayanithy V, West RB, Lee CH, Beck AH, Zhu S, Downs-Kelly E, Montgomery K, Goldblum JR, Hogendoorn PC, Corless CL, Oliveira AM, Dry SM, Nielsen TO, Rubin BP, Fletcher JA, Fletcher CD, van de Rijn M.

J Pathol. 2010 Jan;220(1):58-70. doi: 10.1002/path.2633.

49.

The utility of FOXO1 fluorescence in situ hybridization (FISH) in formalin-fixed paraffin-embedded specimens in the diagnosis of alveolar rhabdomyosarcoma.

Downs-Kelly E, Shehata BM, López-Terrada D, Weaver J, Patel RM, Hartke M, Tubbs RR, Skacel M, Goldblum JR.

Diagn Mol Pathol. 2009 Sep;18(3):138-43. doi: 10.1097/PDM.0b013e31818c2ea4.

PMID:
19704258
50.

Matrix-producing carcinoma of the breast: an aggressive subtype of metaplastic carcinoma.

Downs-Kelly E, Nayeemuddin KM, Albarracin C, Wu Y, Hunt KK, Gilcrease MZ.

Am J Surg Pathol. 2009 Apr;33(4):534-41. doi: 10.1097/PAS.0b013e31818ab26e.

PMID:
19047898

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