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Lessons Learned: Implementation of Pilot Universal Postpartum Nurse Home Visiting Program, Massachusetts 2013-2016.

Stetler K, Silva C, Manning SE, Harvey EM, Posner E, Walmer B, Downs K, Kotelchuck M.

Matern Child Health J. 2018 Jan;22(1):11-16. doi: 10.1007/s10995-017-2385-x.


Extragonadal primordial germ cells or placental progenitor cells?

Downs KM.

Reprod Biomed Online. 2018 Jan;36(1):6-11. doi: 10.1016/j.rbmo.2017.09.013. Epub 2017 Oct 14.


Endothelial Mineralocorticoid Receptor Mediates Parenchymal Arteriole and Posterior Cerebral Artery Remodeling During Angiotensin II-Induced Hypertension.

Diaz-Otero JM, Fisher C, Downs K, Moss ME, Jaffe IZ, Jackson WF, Dorrance AM.

Hypertension. 2017 Dec;70(6):1113-1121. doi: 10.1161/HYPERTENSIONAHA.117.09598. Epub 2017 Oct 3.


Visceral endoderm and the primitive streak interact to build the fetal-placental interface of the mouse gastrula.

Rodriguez AM, Downs KM.

Dev Biol. 2017 Dec 1;432(1):98-124. doi: 10.1016/j.ydbio.2017.08.026. Epub 2017 Sep 5.


Characterization of Macrophage Polarization States Using Combined Measurement of 2-Deoxyglucose and Glutamine Accumulation: Implications for Imaging of Atherosclerosis.

Tavakoli S, Downs K, Short JD, Nguyen HN, Lai Y, Jerabek PA, Goins B, Toczek J, Sadeghi MM, Asmis R.

Arterioscler Thromb Vasc Biol. 2017 Oct;37(10):1840-1848. doi: 10.1161/ATVBAHA.117.308848. Epub 2017 Aug 10.


Generation of multipotent induced cardiac progenitor cells from mouse fibroblasts and potency testing in ex vivo mouse embryos.

Lalit PA, Rodriguez AM, Downs KM, Kamp TJ.

Nat Protoc. 2017 May;12(5):1029-1054. doi: 10.1038/nprot.2017.021. Epub 2017 Apr 20.


Brachyury drives formation of a distinct vascular branchpoint critical for fetal-placental arterial union in the mouse gastrula.

Rodriguez AM, Jin DX, Wolfe AD, Mikedis MM, Wierenga L, Hashmi MP, Viebahn C, Downs KM.

Dev Biol. 2017 May 15;425(2):208-222. doi: 10.1016/j.ydbio.2017.03.032. Epub 2017 Apr 4.


STELLA collaborates in distinct mesendodermal cell subpopulations at the fetal-placental interface in the mouse gastrula.

Wolfe AD, Rodriguez AM, Downs KM.

Dev Biol. 2017 May 1;425(1):44-57. doi: 10.1016/j.ydbio.2017.03.014. Epub 2017 Mar 18.


Differential Regulation of Macrophage Glucose Metabolism by Macrophage Colony-stimulating Factor and Granulocyte-Macrophage Colony-stimulating Factor: Implications for 18F FDG PET Imaging of Vessel Wall Inflammation.

Tavakoli S, Short JD, Downs K, Nguyen HN, Lai Y, Zhang W, Jerabek P, Goins B, Sadeghi MM, Asmis R.

Radiology. 2017 Apr;283(1):87-97. doi: 10.1148/radiol.2016160839. Epub 2016 Nov 16.


PRDM1/BLIMP1 is widely distributed to the nascent fetal-placental interface in the mouse gastrula.

Mikedis MM, Downs KM.

Dev Dyn. 2017 Jan;246(1):50-71. doi: 10.1002/dvdy.24461. Epub 2016 Nov 12.


Irx4 Marks a Multipotent, Ventricular-Specific Progenitor Cell.

Nelson DO, Lalit PA, Biermann M, Markandeya YS, Capes DL, Addesso L, Patel G, Han T, John MC, Powers PA, Downs KM, Kamp TJ, Lyons GE.

Stem Cells. 2016 Dec;34(12):2875-2888. doi: 10.1002/stem.2486. Epub 2016 Sep 13.


Protein Thiol Redox Signaling in Monocytes and Macrophages.

Short JD, Downs K, Tavakoli S, Asmis R.

Antioxid Redox Signal. 2016 Nov 20;25(15):816-835. Epub 2016 Jul 13. Review.


Protein S-Glutathionylation Mediates Macrophage Responses to Metabolic Cues from the Extracellular Environment.

Ullevig SL, Kim HS, Short JD, Tavakoli S, Weintraub ST, Downs K, Asmis R.

Antioxid Redox Signal. 2016 Nov 20;25(15):836-851. Epub 2016 May 17.


Lineage Reprogramming of Fibroblasts into Proliferative Induced Cardiac Progenitor Cells by Defined Factors.

Lalit PA, Salick MR, Nelson DO, Squirrell JM, Shafer CM, Patel NG, Saeed I, Schmuck EG, Markandeya YS, Wong R, Lea MR, Eliceiri KW, Hacker TA, Crone WC, Kyba M, Garry DJ, Stewart R, Thomson JA, Downs KM, Lyons GE, Kamp TJ.

Cell Stem Cell. 2016 Mar 3;18(3):354-67. doi: 10.1016/j.stem.2015.12.001. Epub 2016 Feb 11.


Glutaredoxin 2a overexpression in macrophages promotes mitochondrial dysfunction but has little or no effect on atherogenesis in LDL-receptor null mice.

Zamora DA, Downs KP, Ullevig SL, Tavakoli S, Kim HS, Qiao M, Greaves DR, Asmis R.

Atherosclerosis. 2015 Jul;241(1):69-78. doi: 10.1016/j.atherosclerosis.2015.04.805. Epub 2015 Apr 26.


Mixl1 localizes to putative axial stem cell reservoirs and their posterior descendants in the mouse embryo.

Wolfe AD, Downs KM.

Gene Expr Patterns. 2014 May;15(1):8-20. doi: 10.1016/j.gep.2014.02.002. Epub 2014 Mar 12.


Cortisol release in response to UVB exposure in Xiphophorus fish.

Contreras AJ, Boswell M, Downs KP, Pasquali A, Walter RB.

Comp Biochem Physiol C Toxicol Pharmacol. 2014 Jun;163:95-101. doi: 10.1016/j.cbpc.2014.02.004. Epub 2014 Mar 10.


UVB-induced gene expression in the skin of Xiphophorus maculatus Jp 163 B.

Yang K, Boswell M, Walter DJ, Downs KP, Gaston-Pravia K, Garcia T, Shen Y, Mitchell DL, Walter RB.

Comp Biochem Physiol C Toxicol Pharmacol. 2014 Jun;163:86-94. doi: 10.1016/j.cbpc.2014.01.008. Epub 2014 Feb 17.


Mouse primordial germ cells: a reappraisal.

Mikedis MM, Downs KM.

Int Rev Cell Mol Biol. 2014;309:1-57. doi: 10.1016/B978-0-12-800255-1.00001-6. Review.


Irx4 identifies a chamber-specific cell population that contributes to ventricular myocardium development.

Nelson DO, Jin DX, Downs KM, Kamp TJ, Lyons GE.

Dev Dyn. 2014 Mar;243(3):381-92.


Breast-specific gamma imaging influences surgical management in patients with breast cancer.

Edwards C, Williams S, McSwain AP, Damle S, Rapelyea JA, Downs K, Torrente J, Sambamurty A, Brem RF, Teal CB.

Breast J. 2013 Sep-Oct;19(5):512-9. doi: 10.1111/tbj.12147. Epub 2013 Jul 14.


Peering into a Chilean black box: parental storytelling in pediatric genetic counseling.

Ordonez J, Margarit S, Downs K, Yashar BM.

J Genet Couns. 2013 Dec;22(6):805-16. doi: 10.1007/s10897-013-9620-4. Epub 2013 Jun 29.


Widespread but tissue-specific patterns of interferon-induced transmembrane protein 3 (IFITM3, FRAGILIS, MIL-1) in the mouse gastrula.

Mikedis MM, Downs KM.

Gene Expr Patterns. 2013 Oct;13(7):225-39. doi: 10.1016/j.gep.2013.04.003. Epub 2013 Apr 29.


Gene expression assays for actin, ubiquitin, and three microsatellite-encoding genes in Helianthus annuus (Asteraceae).

Pramod S, Downs KE, Welch ME.

Am J Bot. 2012 Sep;99(9):e350-2. doi: 10.3732/ajb.1200045. Epub 2012 Aug 30.


The hypoblast (visceral endoderm): an evo-devo perspective.

Stern CD, Downs KM.

Development. 2012 Mar;139(6):1059-69. doi: 10.1242/dev.070730. Review.


STELLA-positive subregions of the primitive streak contribute to posterior tissues of the mouse gastrula.

Mikedis MM, Downs KM.

Dev Biol. 2012 Mar 1;363(1):201-18. doi: 10.1016/j.ydbio.2011.10.003. Epub 2011 Oct 8. Erratum in: Dev Biol. 2012 Jun 15;366(2):435.


Lineage Commitments: Emphasis On Embryonic-Extraembryonic Interfaces.

Downs KM.

EMBO Rep. 2011 Sep 30;12(10):987-90. doi: 10.1038/embor.2011.186.


Characterization of telomeres and telomerase expression in Xiphophorus.

Downs KP, Shen Y, Pasquali A, Beldorth I, Savage M, Gallier K, Garcia T, Booth RE, Walter RB.

Comp Biochem Physiol C Toxicol Pharmacol. 2012 Jan;155(1):89-94. doi: 10.1016/j.cbpc.2011.05.005. Epub 2011 May 18.


Statewide innovations to improve services for women with perinatal depression.

Shade M, Miller L, Borst J, English B, Valliere J, Downs K, Herceg-Baron R, Hare I.

Nurs Womens Health. 2011 Apr-May;15(2):126-36. doi: 10.1111/j.1751-486X.2011.01621.x. No abstract available.


Mesothelium of the murine allantois exhibits distinct regional properties.

Daane JM, Enders AC, Downs KM.

J Morphol. 2011 May;272(5):536-56. doi: 10.1002/jmor.10928. Epub 2011 Jan 31.


Subthalamic nucleus stimulation influences expression and suppression of impulsive behaviour in Parkinson's disease.

Wylie SA, Ridderinkhof KR, Elias WJ, Frysinger RC, Bashore TR, Downs KE, van Wouwe NC, van den Wildenberg WP.

Brain. 2010 Dec;133(Pt 12):3611-24. doi: 10.1093/brain/awq239. Epub 2010 Sep 22.


Upregulation of imprinted genes in mice: an insight into the intensity of gene expression and the evolution of genomic imprinting.

Zaitoun I, Downs KM, Rosa GJ, Khatib H.

Epigenetics. 2010 Feb 16;5(2):149-58. Epub 2010 Mar 1.


Coverage with Evidence Development: applications and issues.

Trueman P, Grainger DL, Downs KE.

Int J Technol Assess Health Care. 2010 Jan;26(1):79-85. doi: 10.1017/S0266462309990882.


Workplace productivity, employment issues, and resource utilization in patients with bipolar I disorder.

McMorris BJ, Downs KE, Panish JM, Dirani R.

J Med Econ. 2010 Mar;13(1):23-32. doi: 10.3111/13696990903475833.


The enigmatic primitive streak: prevailing notions and challenges concerning the body axis of mammals.

Downs KM.

Bioessays. 2009 Aug;31(8):892-902. doi: 10.1002/bies.200900038. Review.


The impact of migraine and the effect of migraine treatment on workplace productivity in the United States and suggestions for future research.

Burton WN, Landy SH, Downs KE, Runken MC.

Mayo Clin Proc. 2009 May;84(5):436-45. doi: 10.1016/S0025-6196(11)60562-4. Review.


The Allantoic Core Domain: new insights into development of the murine allantois and its relation to the primitive streak.

Downs KM, Inman KE, Jin DX, Enders AC.

Dev Dyn. 2009 Mar;238(3):532-53. doi: 10.1002/dvdy.21862.


Knowledge of prenatal health care among Costa Rican and Panamanian women.

Guilford WH, Downs KE, Royce TJ.

Rev Panam Salud Publica. 2008 Jun;23(6):369-76.


Diversity in genetic counseling: past, present and future.

Mittman IS, Downs K.

J Genet Couns. 2008 Aug;17(4):301-13. doi: 10.1007/s10897-008-9160-5. Epub 2008 Jun 17. Review.


Embryological origins of the human individual.

Downs KM.

DNA Cell Biol. 2008 Jan;27(1):3-7.


Molecular testing for hereditary retinal disease as part of clinical care.

Downs K, Zacks DN, Caruso R, Karoukis AJ, Branham K, Yashar BM, Haimann MH, Trzupek K, Meltzer M, Blain D, Richards JE, Weleber RG, Heckenlively JR, Sieving PA, Ayyagari R.

Arch Ophthalmol. 2007 Feb;125(2):252-8.


The allantois and chorion, when isolated before circulation or chorio-allantoic fusion, have hematopoietic potential.

Zeigler BM, Sugiyama D, Chen M, Guo Y, Downs KM, Speck NA.

Development. 2006 Nov;133(21):4183-92.


Effect of smoking status on productivity loss.

Bunn WB 3rd, Stave GM, Downs KE, Alvir JM, Dirani R.

J Occup Environ Med. 2006 Oct;48(10):1099-108.


Brachyury is required for elongation and vasculogenesis in the murine allantois.

Inman KE, Downs KM.

Development. 2006 Aug;133(15):2947-59.


Localization of Brachyury (T) in embryonic and extraembryonic tissues during mouse gastrulation.

Inman KE, Downs KM.

Gene Expr Patterns. 2006 Oct;6(8):783-93. Epub 2006 Mar 20.


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