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Heritable genetic variation but no local adaptation in a pine-ectomycorrhizal interaction.

Downie J, Silvertown J, Cavers S, Ennos R.

Mycorrhiza. 2020 Feb 20. doi: 10.1007/s00572-020-00941-3. [Epub ahead of print]


A Closer Look at a Multi-Targeted Approach to Hair Loss in African American Women

Burgess C, Roberts W, Downie J, Kera M, Kogan S, Belpulsi D.

J Drugs Dermatol. 2020 Jan 1;19(1):95-98. No abstract available.


Racial and Ethnic Differences in Self-Assessed Facial Aging in Women: Results From a Multinational Study.

Alexis AF, Grimes P, Boyd C, Downie J, Drinkwater A, Garcia JK, Gallagher CJ.

Dermatol Surg. 2019 Dec;45(12):1635-1648. doi: 10.1097/DSS.0000000000002237.


DaxibotulinumtoxinA for Injection for the Treatment of Glabellar Lines: Results from Each of Two Multicenter, Randomized, Double-Blind, Placebo-Controlled, Phase 3 Studies (SAKURA 1 and SAKURA 2).

Carruthers JD, Fagien S, Joseph JH, Humphrey SD, Biesman BS, Gallagher CJ, Liu Y, Rubio RG, Cohen JL, Ho S, Cox SE, Soderberg J, Swift A, Borsuk D, Papanastasiou V, Shamban A, Simzar S, Bertucci V, Waller B, Boyd C, Katz M, Churchill L, Smith S, Burgess C, Dhir K, Draelos Z, Draelos M, Rosen N, Muhn C, Bhatia AC, Desai S, Hsu TS, Kelly CT, Brazell BM, Downie J, Katz B, Woody M, Lupo M, Souyoul S, Mariwalla K, Eviatar J, Werschler WP, Schade S, Glogau RG, Jones D, Black JM, Wesley N, Kaufman-Janette J, Schlessinger J, Hall J, Perillo S, Dover J, Morton L, Solish N, Monheit G, Essig H, Yoelin S, Yoelin S; SAKURA 1 and SAKURA 2 Investigator Group; SAKURA 1 and SAKURA 2 Investigator Group includes the following.

Plast Reconstr Surg. 2020 Jan;145(1):45-58. doi: 10.1097/PRS.0000000000006327.


Understanding the Female African American Facial Aesthetic Patient

Alexis A, Boyd C, Callender V, Downie J, Sangha S.

J Drugs Dermatol. 2019 Sep 1;18(9):858-866..


Atypical Receptor Kinase RINRK1 Required for Rhizobial Infection But Not Nodule Development in Lotus japonicus.

Li X, Zheng Z, Kong X, Xu J, Qiu L, Sun J, Reid D, Jin H, Andersen SU, Oldroyd GED, Stougaard J, Downie JA, Xie F.

Plant Physiol. 2019 Oct;181(2):804-816. doi: 10.1104/pp.19.00509. Epub 2019 Aug 13.


Glomangioma: rare case of a painful lump in the upper lip.

Hamilton AR, Paton A, Downie JJ.

Br J Oral Maxillofac Surg. 2019 Oct;57(8):788-790. doi: 10.1016/j.bjoms.2019.07.005. Epub 2019 Jul 23.


Myths and Knowledge Gaps in the Aesthetic Treatment of Patients With Skin of Color

Alexis AF, Few J, Callender VD, Grimes P, Downie J, Boyd C, Gallagher CJ.

J Drugs Dermatol. 2019 Jul 1;18(7):616-622.


Unsound Evaluations of Medical Machine Translation Risk Patient Health and Confidentiality.

Downie J, Dickson A.

JAMA Intern Med. 2019 Jul 1;179(7):1001. doi: 10.1001/jamainternmed.2019.1856. No abstract available.


Comparing the attitudes of four groups of stakeholders from Quebec, Canada, toward extending medical aid in dying to incompetent patients with dementia.

Bravo G, Trottier L, Rodrigue C, Arcand M, Downie J, Dubois MF, Kaasalainen S, Hertogh CM, Pautex S, Van den Block L.

Int J Geriatr Psychiatry. 2019 Jul;34(7):1078-1086. doi: 10.1002/gps.5111. Epub 2019 Apr 29.


Lip and Perioral Enhancement With Hyaluronic Acid Dermal Fillers in Individuals With Skin of Color.

Taylor SC, Downie JB, Shamban A, Few J, Weichman BM, Schumacher A, Gallagher CJ.

Dermatol Surg. 2019 Jul;45(7):959-967. doi: 10.1097/DSS.0000000000001842.


Transcriptomic analysis of Rhizobium leguminosarum bacteroids in determinate and indeterminate nodules.

Green RT, East AK, Karunakaran R, Downie JA, Poole PS.

Microb Genom. 2019 Feb;5(2). doi: 10.1099/mgen.0.000254. Epub 2019 Feb 19.


Early Pars Plana Vitrectomy for Treatment of Acute Infective Endophthalmitis.

Ho IV, Fernandez-Sanz G, Levasseur S, Ting E, Liew G, Playfair J, Downie J, Gorbatov M, Hunyor AP, Chang AA.

Asia Pac J Ophthalmol (Phila). 2019 Jan-Feb;8(1):3-7. doi: 10.22608/APO.2018414. Epub 2019 Jan 22.


BPX-01 Minocycline Topical Gel Shows Promise for the Treatment of Moderate-to-severe Inflammatory Acne Vulgaris.

Alexis A, Del Rosso JQ, Desai SR, Downie JB, Draelos ZD, Feser C, Forconi R, Fowler JF Jr, Gold M, Kaufman-Janette J, Lain E, Lee M, Ling M, Shamban AT, Werschler WP, Daniels A.

J Clin Aesthet Dermatol. 2018 Nov;11(11):25-35. Epub 2018 Nov 1.


Précisions nécessaires dans la loi du Canada sur l’aide médicale à mourir.

Grant DAG, Downie J.

Can Fam Physician. 2018 Sep;64(9):e364-e365. French. No abstract available.

Free PMC Article

Time to clarify Canada's medical assistance in dying law.

Grant DAG, Downie J.

Can Fam Physician. 2018 Sep;64(9):641-642. No abstract available.


Quebec physicians' perspectives on medical aid in dying for incompetent patients with dementia.

Bravo G, Rodrigue C, Arcand M, Downie J, Dubois MF, Kaasalainen S, Hertogh CM, Pautex S, Van den Block L, Trottier L.

Can J Public Health. 2018 Dec;109(5-6):729-739. doi: 10.17269/s41997-018-0115-9. Epub 2018 Aug 27.


Expression of the Arabidopsis thaliana immune receptor EFR in Medicago truncatula reduces infection by a root pathogenic bacterium, but not nitrogen-fixing rhizobial symbiosis.

Pfeilmeier S, George J, Morel A, Roy S, Smoker M, Stransfeld L, Downie JA, Peeters N, Malone JG, Zipfel C.

Plant Biotechnol J. 2019 Mar;17(3):569-579. doi: 10.1111/pbi.12999. Epub 2018 Sep 13.


Transmission of wireless signals using space division multiplexing in few mode fibers.

Liang X, Li WL, Wood WA, Downie JD, Hurley JE, Ng'oma A.

Opt Express. 2018 Aug 6;26(16):20507-20518. doi: 10.1364/OE.26.020507.


The ash dieback invasion of Europe was founded by two genetically divergent individuals.

McMullan M, Rafiqi M, Kaithakottil G, Clavijo BJ, Bilham L, Orton E, Percival-Alwyn L, Ward BJ, Edwards A, Saunders DGO, Garcia Accinelli G, Wright J, Verweij W, Koutsovoulos G, Yoshida K, Hosoya T, Williamson L, Jennings P, Ioos R, Husson C, Hietala AM, Vivian-Smith A, Solheim H, MaClean D, Fosker C, Hall N, Brown JKM, Swarbreck D, Blaxter M, Downie JA, Clark MD.

Nat Ecol Evol. 2018 Jun;2(6):1000-1008. doi: 10.1038/s41559-018-0548-9. Epub 2018 Apr 23.


Efficacy, Safety, and Tolerability of Topical Dapsone Gel, 7.5% for Treatment of Acne Vulgaris by Fitzpatrick Skin Phototype.

Taylor SC, Cook-Bolden FE, McMichael A, Downie JB, Rodriguez DA, Alexis AF, Callender VD, Alvandi N.

J Drugs Dermatol. 2018 Feb 1;17(2):160-167.


Nurses' perspectives on whether medical aid in dying should be accessible to incompetent patients with dementia: findings from a survey conducted in Quebec, Canada.

Bravo G, Rodrigue C, Arcand M, Downie J, Dubois MF, Kaasalaine S, Hertogh CM, Pautex S, Van den Block L.

Geriatr Nurs. 2018 Jul - Aug;39(4):393-399. doi: 10.1016/j.gerinurse.2017.12.002. Epub 2018 Jan 3.


Are Informal Caregivers of Persons With Dementia Open to Extending Medical Aid in Dying to Incompetent Patients? Findings From a Survey Conducted in Quebec, Canada.

Bravo G, Rodrigue C, Arcand M, Downie J, Dubois MF, Kaasalainen S, Hertogh CM, Pautex S, Van den Block L.

Alzheimer Dis Assoc Disord. 2018 Jul-Sep;32(3):247-254. doi: 10.1097/WAD.0000000000000238.


Should Medical Assistance in Dying Be Extended to Incompetent Patients With Dementia? Research Protocol of a Survey Among Four Groups of Stakeholders From Quebec, Canada.

Bravo G, Rodrigue C, Thériault V, Arcand M, Downie J, Dubois MF, Kaasalainen S, Hertogh CM, Pautex S, Van den Block L.

JMIR Res Protoc. 2017 Nov 13;6(11):e208. doi: 10.2196/resprot.8118.


Ash dieback epidemic in Europe: How can molecular technologies help?

Downie JA.

PLoS Pathog. 2017 Jul 20;13(7):e1006381. doi: 10.1371/journal.ppat.1006381. eCollection 2017 Jul. Review. No abstract available.


Treatment Response With Once-Daily Topical Dapsone Gel, 7.5% for Acne Vulgaris: Subgroup Analysis of Pooled Data from Two Randomized, Double-Blind Stu.

Draelos ZD, Rodriguez DA, Kempers SE, Bruce S, Peredo MI, Downie J, Chang-Lin JE, Berk DR, Ruan S, Kaoukhov A.

J Drugs Dermatol. 2017 Jun 1;16(6):591-598.


The evolving genetic risk for sporadic ALS.

Gibson SB, Downie JM, Tsetsou S, Feusier JE, Figueroa KP, Bromberg MB, Jorde LB, Pulst SM.

Neurology. 2017 Jul 18;89(3):226-233. doi: 10.1212/WNL.0000000000004109. Epub 2017 Jun 22.


The ERN1 transcription factor gene is a target of the CCaMK/CYCLOPS complex and controls rhizobial infection in Lotus japonicus.

Cerri MR, Wang Q, Stolz P, Folgmann J, Frances L, Katzer K, Li X, Heckmann AB, Wang TL, Downie JA, Klingl A, de Carvalho-Niebel F, Xie F, Parniske M.

New Phytol. 2017 Jul;215(1):323-337. doi: 10.1111/nph.14547. Epub 2017 May 15.


Bacterial Biosensors for in Vivo Spatiotemporal Mapping of Root Secretion.

Pini F, East AK, Appia-Ayme C, Tomek J, Karunakaran R, Mendoza-Suárez M, Edwards A, Terpolilli JJ, Roworth J, Downie JA, Poole PS.

Plant Physiol. 2017 Jul;174(3):1289-1306. doi: 10.1104/pp.16.01302. Epub 2017 May 11.


Evolutionary history of Tibetans inferred from whole-genome sequencing.

Hu H, Petousi N, Glusman G, Yu Y, Bohlender R, Tashi T, Downie JM, Roach JC, Cole AM, Lorenzo FR, Rogers AR, Brunkow ME, Cavalleri G, Hood L, Alpatty SM, Prchal JT, Jorde LB, Robbins PA, Simonson TS, Huff CD.

PLoS Genet. 2017 Apr 27;13(4):e1006675. doi: 10.1371/journal.pgen.1006675. eCollection 2017 Apr.


Manganese transport is essential for N2 -fixation by Rhizobium leguminosarum in bacteroids from galegoid but not phaseoloid nodules.

Hood G, Ramachandran V, East AK, Downie JA, Poole PS.

Environ Microbiol. 2017 Jul;19(7):2715-2726. doi: 10.1111/1462-2920.13773. Epub 2017 May 30.


Morphotype of bacteroids in different legumes correlates with the number and type of symbiotic NCR peptides.

Montiel J, Downie JA, Farkas A, Bihari P, Herczeg R, Bálint B, Mergaert P, Kereszt A, Kondorosi É.

Proc Natl Acad Sci U S A. 2017 May 9;114(19):5041-5046. doi: 10.1073/pnas.1704217114. Epub 2017 Apr 24.


Measurements and modeling of multipath interference at wavelengths below cable cut-off in a G.654 optical fiber span.

Downie JD, Hurley J, DePedro H, Garner S, Blaker J, Zakharian A, Ten S, Mills G.

Opt Express. 2017 Apr 17;25(8):9305-9311. doi: 10.1364/OE.25.009305.


Combination of In-Office Chemical Peels With a Topical Comprehensive Pigmentation Control Product in Skin of Color Subjects With Facial Hyperpigmentation.

Downie J, Schneider K, Goberdhan L, Makino ET, Mehta RC.

J Drugs Dermatol. 2017 Apr 1;16(4):301-306.


MtLAX2, a Functional Homologue of the Arabidopsis Auxin Influx Transporter AUX1, Is Required for Nodule Organogenesis.

Roy S, Robson F, Lilley J, Liu CW, Cheng X, Wen J, Walker S, Sun J, Cousins D, Bone C, Bennett MJ, Downie JA, Swarup R, Oldroyd G, Murray JD.

Plant Physiol. 2017 May;174(1):326-338. doi: 10.1104/pp.16.01473. Epub 2017 Mar 31.


Abortion care in Canada is decided between a woman and her doctor, without recourse to criminal law.

Norman WV, Downie J.

BMJ. 2017 Mar 24;356:j1506. doi: 10.1136/bmj.j1506. No abstract available.


Development and Application of an eDNA Method to Detect the Critically Endangered Trinidad Golden Tree Frog (Phytotriades auratus) in Bromeliad Phytotelmata.

Brozio S, Manson C, Gourevitch E, Burns TJ, Greener MS, Downie JR, Hoskisson PA.

PLoS One. 2017 Feb 15;12(2):e0170619. doi: 10.1371/journal.pone.0170619. eCollection 2017.


Dengue Fever-Associated Maculopathy and Panuveitis in Australia.

Ooi KG, Inglis H, Paramanathan N, Downie JA, Hennessy MP.

Case Rep Ophthalmol Med. 2016;2016:5704695. doi: 10.1155/2016/5704695. Epub 2016 Dec 19.


Genome sequence and genetic diversity of European ash trees.

Sollars ES, Harper AL, Kelly LJ, Sambles CM, Ramirez-Gonzalez RH, Swarbreck D, Kaithakottil G, Cooper ED, Uauy C, Havlickova L, Worswick G, Studholme DJ, Zohren J, Salmon DL, Clavijo BJ, Li Y, He Z, Fellgett A, McKinney LV, Nielsen LR, Douglas GC, Kjær ED, Downie JA, Boshier D, Lee S, Clark J, Grant M, Bancroft I, Caccamo M, Buggs RJ.

Nature. 2017 Jan 12;541(7636):212-216. doi: 10.1038/nature20786. Epub 2016 Dec 26.


Global Updates on the Future Directions of Neurotoxins and Fillers.

Downie JB, Patel A, Heningburg J.

Plast Reconstr Surg Glob Open. 2016 Dec 14;4(12 Suppl Anatomy and Safety in Cosmetic Medicine: Cosmetic Bootcamp):e1177. doi: 10.1097/GOX.0000000000001177. eCollection 2016 Dec.


Genomic characterization of pediatric B-lymphoblastic lymphoma and B-lymphoblastic leukemia using formalin-fixed tissues.

Meyer JA, Zhou D, Mason CC, Downie JM, Rodic V, Abromowitch M, Wistinghausen B, Termuhlen AM, Angiolillo AL, Perkins SL, Lones MA, Barnette P, Schiffman JD, Miles RR.

Pediatr Blood Cancer. 2017 Jul;64(7). doi: 10.1002/pbc.26363. Epub 2016 Dec 13.


Development and production of good manufacturing practice grade human embryonic stem cell lines as source material for clinical application.

De Sousa PA, Downie JM, Tye BJ, Bruce K, Dand P, Dhanjal S, Serhal P, Harper J, Turner M, Bateman M.

Stem Cell Res. 2016 Sep;17(2):379-390. doi: 10.1016/j.scr.2016.08.011. Epub 2016 Aug 26.


Combined variants in factor VIII and prostaglandin synthase-1 amplify hemorrhage severity across three generations of descendants.

Nance D, Campbell RA, Rowley JW, Downie JM, Jorde LB, Kahr WH, Mereby SA, Tolley ND, Zimmerman GA, Weyrich AS, Rondina MT.

J Thromb Haemost. 2016 Nov;14(11):2230-2240. doi: 10.1111/jth.13500. Epub 2016 Oct 20.


Turning into frogs: Asymmetry in forelimb emergence and escape direction in metamorphosing anurans.

Zechini L, Lilley A, Waddell E, Burns TJ, Downie JR, Walsh PT.

Laterality. 2017 Nov;22(6):641-653. doi: 10.1080/1357650X.2016.1235175. Epub 2016 Sep 26.


Rising trends of endogenous Klebsiella pneumoniae endophthalmitis in Australia.

Odouard C, Ong D, Shah PR, Gin T, Allen PJ, Downie J, Lim LL, McCluskey P.

Clin Exp Ophthalmol. 2017 Mar;45(2):135-142. doi: 10.1111/ceo.12827. Epub 2016 Sep 15.


Derivation of the clinical grade human embryonic stem cell line RCe015-A (RC-11).

De Sousa PA, Tye BJ, Bruce K, Dand P, Russell G, Collins DM, Greenshields A, McDonald K, Bradburn H, Laurie A, Canham M, Kunath T, Downie JM, Bateman M, Courtney A.

Stem Cell Res. 2016 Jul;17(1):42-48. doi: 10.1016/j.scr.2016.04.021. Epub 2016 May 7.


Derivation of the clinical grade human embryonic stem cell line RCe013-A (RC-9).

De Sousa PA, Tye BJ, Bruce K, Dand P, Russell G, Collins DM, Greenshields A, McDonald K, Bradburn H, Canham MA, Kunath T, Downie JM, Bateman M, Courtney A.

Stem Cell Res. 2016 Jul;17(1):36-41. doi: 10.1016/j.scr.2016.04.020. Epub 2016 May 6.


Derivation of the clinical grade human embryonic stem cell line RCe021-A (RC-17).

De Sousa PA, Tye BJ, Bruce K, Dand P, Russell G, Collins DM, Greenshields A, McDonald K, Bradburn H, Allan D, Laurie A, Kunath T, Canham MA, Downie JM, Bateman M, Courtney A.

Stem Cell Res. 2016 Jul;17(1):1-5. doi: 10.1016/j.scr.2016.04.019. Epub 2016 Apr 30.


A Genome-Wide Search for Greek and Jewish Admixture in the Kashmiri Population.

Downie JM, Tashi T, Lorenzo FR, Feusier JE, Mir H, Prchal JT, Jorde LB, Koul PA.

PLoS One. 2016 Aug 4;11(8):e0160614. doi: 10.1371/journal.pone.0160614. eCollection 2016.


Derivation of the clinical grade human embryonic stem cell line RCe020-a (RC-16).

De Sousa PA, Tye BJ, Bruce K, Dand P, Russell G, Collins DM, Greenshields A, McDonald K, Bradburn H, Laurie A, Downie JM, Bateman M, Courtney A.

Stem Cell Res. 2016 May;16(3):790-4. doi: 10.1016/j.scr.2016.04.002. Epub 2016 Apr 9.

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