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Items: 33

1.

Wholegrain Particle Size Influences Postprandial Glycemia in Type 2 Diabetes: A Randomized Crossover Study Comparing Four Wholegrain Breads.

Reynolds AN, Mann J, Elbalshy M, Mete E, Robinson C, Oey I, Silcock P, Downes N, Perry T, Te Morenga L.

Diabetes Care. 2020 Feb;43(2):476-479. doi: 10.2337/dc19-1466. Epub 2019 Nov 19.

PMID:
31744812
2.

Internal hernia through the foramen of Winslow.

Downs P, Downes N, Zayshlyy E, Esper C, Giuseppucci P.

J Surg Case Rep. 2018 Dec 11;2018(12):rjy329. doi: 10.1093/jscr/rjy329. eCollection 2018 Dec.

3.

Transcriptional Profiling of Hypoxia-Regulated Non-coding RNAs in Human Primary Endothelial Cells.

Moreau PR, Örd T, Downes NL, Niskanen H, Bouvy-Liivrand M, Aavik E, Ylä-Herttuala S, Kaikkonen MU.

Front Cardiovasc Med. 2018 Nov 5;5:159. doi: 10.3389/fcvm.2018.00159. eCollection 2018.

4.

Differential but Complementary HIF1α and HIF2α Transcriptional Regulation.

Downes NL, Laham-Karam N, Kaikkonen MU, Ylä-Herttuala S.

Mol Ther. 2018 Jul 5;26(7):1735-1745. doi: 10.1016/j.ymthe.2018.05.004. Epub 2018 May 9.

5.

An immunologically relevant rodent model demonstrates safety of therapy using a tumour-specific IgE.

Josephs DH, Nakamura M, Bax HJ, Dodev TS, Muirhead G, Saul L, Karagiannis P, Ilieva KM, Crescioli S, Gazinska P, Woodman N, Lombardelli C, Kareemaghay S, Selkirk C, Lentfer H, Barton C, Canevari S, Figini M, Downes N, Dombrowicz D, Corrigan CJ, Nestle FO, Jones PS, Gould HJ, Blower PJ, Tsoka S, Spicer JF, Karagiannis SN.

Allergy. 2018 Dec;73(12):2328-2341. doi: 10.1111/all.13455. Epub 2018 Oct 8.

6.

An innovative investigative approach to characterize the effects observed in a combined fertility study in male and female rats.

Xie J, Funk J, Bopst M, Ottaviani G, Downes N, Hackford S, Villabruna L, Schmitt G, Barrow P.

Regul Toxicol Pharmacol. 2018 Jun;95:339-347. doi: 10.1016/j.yrtph.2018.04.007. Epub 2018 Apr 7.

PMID:
29635059
7.

Consideration of the Development of the Gastrointestinal Tract in the Choice of Species for Regulatory Juvenile Studies.

Downes NJ.

Birth Defects Res. 2018 Jan 15;110(1):56-62. doi: 10.1002/bdr2.1119. Epub 2017 Sep 5.

PMID:
28872769
8.

Reductive Metabolism Influences the Toxicity and Pharmacokinetics of the Hypoxia-Targeted Benzotriazine Di-Oxide Anticancer Agent SN30000 in Mice.

Gu Y, Chang TT, Wang J, Jaiswal JK, Edwards D, Downes NJ, Liyanage HDS, Lynch CRH, Pruijn FB, Hickey AJR, Hay MP, Wilson WR, Hicks KO.

Front Pharmacol. 2017 Aug 11;8:531. doi: 10.3389/fphar.2017.00531. eCollection 2017.

9.

Anti-Folate Receptor-α IgE but not IgG Recruits Macrophages to Attack Tumors via TNFα/MCP-1 Signaling.

Josephs DH, Bax HJ, Dodev T, Georgouli M, Nakamura M, Pellizzari G, Saul L, Karagiannis P, Cheung A, Herraiz C, Ilieva KM, Correa I, Fittall M, Crescioli S, Gazinska P, Woodman N, Mele S, Chiaruttini G, Gilbert AE, Koers A, Bracher M, Selkirk C, Lentfer H, Barton C, Lever E, Muirhead G, Tsoka S, Canevari S, Figini M, Montes A, Downes N, Dombrowicz D, Corrigan CJ, Beavil AJ, Nestle FO, Jones PS, Gould HJ, Sanz-Moreno V, Blower PJ, Spicer JF, Karagiannis SN.

Cancer Res. 2017 Mar 1;77(5):1127-1141. doi: 10.1158/0008-5472.CAN-16-1829. Epub 2017 Jan 17.

10.

The incidence of congenital malformations and variations in Göttingen minipigs.

Ellemann-Laursen S, Marsden E, Peter B, Downes N, Coulby D, Grossi AB.

Reprod Toxicol. 2016 Sep;64:162-8. doi: 10.1016/j.reprotox.2016.05.006. Epub 2016 May 13.

PMID:
27184860
11.

Benzodiazepine and z-hypnotic prescribing for older people in primary care: a cross-sectional population-based study.

Johnson CF, Frei C, Downes N, McTaggart SA, Akram G.

Br J Gen Pract. 2016 Jun;66(647):e410-5. doi: 10.3399/bjgp16X685213. Epub 2016 Apr 25.

12.

Organ data from the developing Göttingen minipig: first steps towards a juvenile PBPK model.

Van Peer E, Downes N, Casteleyn C, Van Ginneken C, Weeren A, Van Cruchten S.

J Pharmacokinet Pharmacodyn. 2016 Apr;43(2):179-90. doi: 10.1007/s10928-015-9463-8. Epub 2015 Dec 19.

PMID:
26687458
13.

Vehicle Systems and Excipients Used in Minipig Drug Development Studies.

Weaver ML, Grossi AB, Schützsack J, Parish J, Løgsted J, Bøgh IB, Cameron D, Harvey W, Festag M, Downes N, Venturella S, Schlichtiger J, Mhedhbi S, Ross V, Kissner T, Stark C, Milano S, Heining P, Sanchez-Felix M.

Toxicol Pathol. 2016 Apr;44(3):367-72. doi: 10.1177/0192623315613088. Epub 2015 Dec 16. Review.

PMID:
26674803
14.

Regulatory Forum Opinion Piece: Carcinogen Risk Assessment: The Move from Screens to Science.

Downes N, Foster J.

Toxicol Pathol. 2015 Dec;43(8):1064-73. doi: 10.1177/0192623315598578. Epub 2015 Aug 21.

PMID:
26296629
15.

Vigabatrin-induced CNS changes in juvenile rats: Induction, progression and recovery of myelin-related changes.

Rasmussen AD, Richmond E, Wegener KM, Downes N, Mullins P.

Neurotoxicology. 2015 Jan;46:137-44. doi: 10.1016/j.neuro.2014.12.008. Epub 2014 Dec 30.

PMID:
25554247
16.

Circumventing antivector immunity: potential use of nonhuman adenoviral vectors.

Lopez-Gordo E, Podgorski II, Downes N, Alemany R.

Hum Gene Ther. 2014 Apr;25(4):285-300. doi: 10.1089/hum.2013.228. Epub 2014 Mar 25. Review.

17.

The development of myelin in the brain of the juvenile rat.

Downes N, Mullins P.

Toxicol Pathol. 2014 Jul;42(5):913-22. doi: 10.1177/0192623313503518. Epub 2013 Oct 15.

PMID:
24129760
18.

Reviewing long-term antidepressants can reduce drug burden: a prospective observational cohort study.

Johnson CF, Macdonald HJ, Atkinson P, Buchanan AI, Downes N, Dougall N.

Br J Gen Pract. 2012 Nov;62(604):e773-9. doi: 10.3399/bjgp12X658304.

19.

Juvenile toxicity: are we asking the right questions?

Downes N.

Toxicol Pathol. 2012 Jul;40(5):830-7. doi: 10.1177/0192623312439124. Epub 2012 Mar 9.

PMID:
22407308
20.

Revisiting alternative approaches to the assessment of carcinogenic risk.

Downes N.

Toxicol Pathol. 2010 Feb;38(2):324-7. doi: 10.1177/0192623309360214. Epub 2010 Feb 2.

PMID:
20124498
21.

Epidermodysplasia verruciformis-like syndrome in association with systemic lupus erythematosus.

Holmes C, Chong AH, Tabrizi SN, Downes N, Nindl I.

Australas J Dermatol. 2009 Feb;50(1):44-7. doi: 10.1111/j.1440-0960.2008.00502.x.

PMID:
19178492
22.

Switching from latanoprost to fixed-combination latanoprost-timolol: a 21-day, randomized, double-masked, active-control study in patients with glaucoma and ocular hypertension.

Olander K, Zimmerman TJ, Downes N, Schoenfelder J; Xalacom/Latanoprost Study Group.

Clin Ther. 2004 Oct;26(10):1619-29.

PMID:
15598478
23.

Trigeminal trophic syndrome.

Su JC, Downes NP.

Australas J Dermatol. 1997 May;38(2):80-1.

PMID:
9159963
25.

Safety and efficacy of calcipotriol ointment (Dovonex) in treating children with psoriasis vulgaris.

Darley CR, Cunliffe WJ, Green CM, Hutchinson PE, Klaber MR, Downes N.

Br J Dermatol. 1996 Sep;135(3):390-3.

PMID:
8949431
26.

A comparison of the effects of alfacalcidol treatment and vitamin D2 supplementation on calcium absorption in elderly women with vertebral fractures.

Francis RM, Boyle IT, Moniz C, Sutcliffe AM, Davis BS, Beastall GH, Cowan RA, Downes N.

Osteoporos Int. 1996;6(4):284-90.

PMID:
8883116
27.

Comparative effects of calcipotriol (MC903) solution and placebo (vehicle of MC903) in the treatment of psoriasis of the scalp.

Green C, Ganpule M, Harris D, Kavanagh G, Kennedy C, Mallett R, Rustin M, Downes N.

Br J Dermatol. 1994 Apr;130(4):483-7.

PMID:
8186114
28.

Physicians' perceptions of the role of clinical dietitians are changing.

Rosen O, Downes NJ, Sucher KP, Shifflett B.

J Am Diet Assoc. 1991 Sep;91(9):1074-7.

PMID:
1918758
29.

Dietary habits, health beliefs, and food practices of elderly Chinese women.

Chau P, Lee HS, Tseng R, Downes NJ.

J Am Diet Assoc. 1990 Apr;90(4):579-80. No abstract available.

PMID:
2319082
30.

Nutrition-related backgrounds and counseling practices of doctors of chiropractic.

Newman CF, Downes NJ, Tseng RY, McProud LM, Newman LK.

J Am Diet Assoc. 1989 Jul;89(7):939-43.

PMID:
2745912
31.

Southeast Asian renal exchange list.

Ziegler VS, Sucher KP, Downes NJ.

J Am Diet Assoc. 1989 Jan;89(1):85-92. Erratum in: J Am Diet Assoc 1989 May;89(5):622.

PMID:
2909597
32.

Pruritic specific cutaneous infiltrates in leukemia and lymphoma.

Czarnecki DB, Downes NP, O'Brien T.

Arch Dermatol. 1982 Feb;118(2):119-21. No abstract available.

PMID:
6949496
33.

Maintenance problems that should be considered in a building program.

DOWNES NW.

Am J Ment Defic. 1953 Oct;58(2):245-50. No abstract available.

PMID:
13080295

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