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Items: 13

1.

DOT1L inhibition reveals a distinct subset of enhancers dependent on H3K79 methylation.

Godfrey L, Crump NT, Thorne R, Lau IJ, Repapi E, Dimou D, Smith AL, Harman JR, Telenius JM, Oudelaar AM, Downes DJ, Vyas P, Hughes JR, Milne TA.

Nat Commun. 2019 Jun 26;10(1):2803. doi: 10.1038/s41467-019-10844-3.

2.

High-Throughput Genotyping of CRISPR/Cas Edited Cells in 96-Well Plates.

Nussbaum L, Telenius JM, Hill S, Hirschfeld PP, Suciu MC; WIGWAM Consortium, Downes DJ, Hughes JR.

Methods Protoc. 2018 Aug 1;1(3). pii: E29. doi: 10.3390/mps1030029.

3.

Single-allele chromatin interactions identify regulatory hubs in dynamic compartmentalized domains.

Oudelaar AM, Davies JOJ, Hanssen LLP, Telenius JM, Schwessinger R, Liu Y, Brown JM, Downes DJ, Chiariello AM, Bianco S, Nicodemi M, Buckle VJ, Dekker J, Higgs DR, Hughes JR.

Nat Genet. 2018 Dec;50(12):1744-1751. doi: 10.1038/s41588-018-0253-2. Epub 2018 Oct 29.

4.

Impaired DNA demethylation of C/EBP sites causes premature aging.

Schäfer A, Mekker B, Mallick M, Vastolo V, Karaulanov E, Sebastian D, von der Lippen C, Epe B, Downes DJ, Scholz C, Niehrs C.

Genes Dev. 2018 Jun 1;32(11-12):742-762. doi: 10.1101/gad.311969.118. Epub 2018 Jun 8.

5.

Low-input Capture-C: A Chromosome Conformation Capture Assay to Analyze Chromatin Architecture in Small Numbers of Cells.

Oudelaar AM, Downes DJ, Davies JOJ, Hughes JR.

Bio Protoc. 2017 Dec 5;7(23). pii: e2645. doi: 10.21769/BioProtoc.2645.

6.

Robust detection of chromosomal interactions from small numbers of cells using low-input Capture-C.

Oudelaar AM, Davies JOJ, Downes DJ, Higgs DR, Hughes JR.

Nucleic Acids Res. 2017 Dec 15;45(22):e184. doi: 10.1093/nar/gkx1194.

7.

Tissue-specific CTCF-cohesin-mediated chromatin architecture delimits enhancer interactions and function in vivo.

Hanssen LLP, Kassouf MT, Oudelaar AM, Biggs D, Preece C, Downes DJ, Gosden M, Sharpe JA, Sloane-Stanley JA, Hughes JR, Davies B, Higgs DR.

Nat Cell Biol. 2017 Aug;19(8):952-961. doi: 10.1038/ncb3573. Epub 2017 Jul 24.

8.

Functional characterisation of cis-regulatory elements governing dynamic Eomes expression in the early mouse embryo.

Simon CS, Downes DJ, Gosden ME, Telenius J, Higgs DR, Hughes JR, Costello I, Bikoff EK, Robertson EJ.

Development. 2017 Apr 1;144(7):1249-1260. doi: 10.1242/dev.147322. Epub 2017 Feb 7.

9.

Spatial differentiation of gene expression in Aspergillus niger colony grown for sugar beet pulp utilization.

Benoit I, Zhou M, Vivas Duarte A, Downes DJ, Todd RB, Kloezen W, Post H, Heck AJ, Maarten Altelaar AF, de Vries RP.

Sci Rep. 2015 Aug 28;5:13592. doi: 10.1038/srep13592.

10.

Characterization of the mutagenic spectrum of 4-nitroquinoline 1-oxide (4-NQO) in Aspergillus nidulans by whole genome sequencing.

Downes DJ, Chonofsky M, Tan K, Pfannenstiel BT, Reck-Peterson SL, Todd RB.

G3 (Bethesda). 2014 Oct 27;4(12):2483-92. doi: 10.1534/g3.114.014712.

11.

Dual DNA binding and coactivator functions of Aspergillus nidulans TamA, a Zn(II)2Cys6 transcription factor.

Downes DJ, Davis MA, Wong KH, Kreutzberger SD, Hynes MJ, Todd RB.

Mol Microbiol. 2014 Jun;92(6):1198-211. doi: 10.1111/mmi.12620. Epub 2014 May 7.

12.

Multiple nuclear localization signals mediate nuclear localization of the GATA transcription factor AreA.

Hunter CC, Siebert KS, Downes DJ, Wong KH, Kreutzberger SD, Fraser JA, Clarke DF, Hynes MJ, Davis MA, Todd RB.

Eukaryot Cell. 2014 Apr;13(4):527-38. doi: 10.1128/EC.00040-14. Epub 2014 Feb 21.

13.

Regulation of the NADP-glutamate dehydrogenase gene gdhA in Aspergillus nidulans by the Zn(II)2Cys6 transcription factor LeuB.

Downes DJ, Davis MA, Kreutzberger SD, Taig BL, Todd RB.

Microbiology. 2013 Dec;159(Pt 12):2467-80. doi: 10.1099/mic.0.071514-0. Epub 2013 Sep 11.

PMID:
24025604

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