Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 166

1.

TGFβ Inhibition Stimulates Collagen Maturation to Enhance Bone Repair and Fracture Resistance in a Murine Myeloma Model.

Green AC, Lath D, Hudson K, Walkley B, Down JM, Owen R, Evans HR, Paton-Hough J, Reilly GC, Lawson MA, Chantry AD.

J Bone Miner Res. 2019 Dec;34(12):2311-2326. doi: 10.1002/jbmr.3859. Epub 2019 Oct 31.

PMID:
31442332
2.

Current pharmacotherapy options for conduct disorders in adolescents and children.

Khan S, Down J, Aouira N, Bor W, Haywood A, Littlewood R, Heussler H, McDermott B.

Expert Opin Pharmacother. 2019 Apr;20(5):571-583. doi: 10.1080/14656566.2018.1561862. Epub 2019 Jan 31.

PMID:
30702354
3.

Teaching about the Treaty to Prohibit Nuclear Weapons to three generations.

Ashford MW, Down J.

Med Confl Surviv. 2018 Dec;34(4):263-268. doi: 10.1080/13623699.2018.1560624. Epub 2019 Jan 2. No abstract available.

PMID:
30602306
4.

Mechanical ventilation for the non-anaesthetist 2: practical tips.

Matthewman MC, Down J.

Br J Hosp Med (Lond). 2019 Jan 2;80(1):C12-C16. doi: 10.12968/hmed.2019.80.1.C12. No abstract available.

PMID:
30592673
5.

Mechanical ventilation for the non-anaesthetist 1: physiology and mechanics.

Matthewman MC, Down J.

Br J Hosp Med (Lond). 2018 Dec 2;79(12):C188-C192. doi: 10.12968/hmed.2018.79.12.C188. No abstract available.

PMID:
30526105
6.

Preventing and Repairing Myeloma Bone Disease by Combining Conventional Antiresorptive Treatment With a Bone Anabolic Agent in Murine Models.

Paton-Hough J, Tazzyman S, Evans H, Lath D, Down JM, Green AC, Snowden JA, Chantry AD, Lawson MA.

J Bone Miner Res. 2019 May;34(5):783-796. doi: 10.1002/jbmr.3606. Epub 2018 Nov 26.

7.

ARQ-197, a small-molecule inhibitor of c-Met, reduces tumour burden and prevents myeloma-induced bone disease in vivo.

Lath DL, Buckle CH, Evans HR, Fisher M, Down JM, Lawson MA, Chantry AD.

PLoS One. 2018 Jun 20;13(6):e0199517. doi: 10.1371/journal.pone.0199517. eCollection 2018.

8.

Ex Vivo Selection of Transduced Hematopoietic Stem Cells for Gene Therapy of β-Hemoglobinopathies.

Bhukhai K, de Dreuzy E, Giorgi M, Colomb C, Negre O, Denaro M, Gillet-Legrand B, Cheuzeville J, Paulard A, Trebeden-Negre H, Borwornpinyo S, Sii-Felice K, Maouche L, Down JD, Leboulch P, Payen E.

Mol Ther. 2018 Feb 7;26(2):480-495. doi: 10.1016/j.ymthe.2017.10.015. Epub 2017 Oct 24.

9.

Melphalan modifies the bone microenvironment by enhancing osteoclast formation.

Chai RC, McDonald MM, Terry RL, Kovačić N, Down JM, Pettitt JA, Mohanty ST, Shah S, Haffari G, Xu J, Gillespie MT, Rogers MJ, Price JT, Croucher PI, Quinn JMW.

Oncotarget. 2017 Jul 10;8(40):68047-68058. doi: 10.18632/oncotarget.19152. eCollection 2017 Sep 15.

10.

Low-dose methotrexate in myeloproliferative neoplasm models.

Chinnaiya K, Lawson MA, Thomas S, Haider MT, Down J, Chantry AD, Hughes D, Green A, Sayers JR, Snowden JA, Zeidler MP.

Haematologica. 2017 Sep;102(9):e336-e339. doi: 10.3324/haematol.2017.165738. Epub 2017 May 26. No abstract available.

11.

Perceived barriers that prevent high school students seeking help from teachers for bullying and their effects on disclosure intentions.

Boulton MJ, Boulton L, Down J, Sanders J, Craddock H.

J Adolesc. 2017 Apr;56:40-51. doi: 10.1016/j.adolescence.2016.11.009. Epub 2017 Jan 29.

PMID:
28147302
12.

Enhancing Primary School Children's Knowledge of Online Safety and Risks with the CATZ Cooperative Cross-Age Teaching Intervention: Results from a Pilot Study.

Boulton MJ, Boulton L, Camerone E, Down J, Hughes J, Kirkbride C, Kirkham R, Macaulay P, Sanders J.

Cyberpsychol Behav Soc Netw. 2016 Oct;19(10):609-614.

PMID:
27732078
13.

A survey of changing trends in modelling radiation lung injury in mice: bringing out the good, the bad, and the uncertain.

Dabjan MB, Buck CM, Jackson IL, Vujaskovic Z, Marples B, Down JD.

Lab Invest. 2016 Sep;96(9):936-49. doi: 10.1038/labinvest.2016.76. Epub 2016 Aug 1. Review.

14.

Polonium-210 poisoning: a first-hand account.

Nathwani AC, Down JF, Goldstone J, Yassin J, Dargan PI, Virchis A, Gent N, Lloyd D, Harrison JD.

Lancet. 2016 Sep 10;388(10049):1075-1080. doi: 10.1016/S0140-6736(16)00144-6. Epub 2016 Jul 23.

PMID:
27461439
15.

Osteoclasts control reactivation of dormant myeloma cells by remodelling the endosteal niche.

Lawson MA, McDonald MM, Kovacic N, Hua Khoo W, Terry RL, Down J, Kaplan W, Paton-Hough J, Fellows C, Pettitt JA, Neil Dear T, Van Valckenborgh E, Baldock PA, Rogers MJ, Eaton CL, Vanderkerken K, Pettit AR, Quinn JM, Zannettino AC, Phan TG, Croucher PI.

Nat Commun. 2015 Dec 3;6:8983. doi: 10.1038/ncomms9983.

16.

Microdosimetric and Biological Effects of Photon Irradiation at Different Energies in Bone Marrow.

Belley MD, Ashcraft KA, Lee CT, Cornwall-Brady MR, Chen JJ, Gunasingha R, Burkhart M, Dewhirst M, Yoshizumi TT, Down JD.

Radiat Res. 2015 Oct;184(4):378-91. doi: 10.1667/RR14095.1. Epub 2015 Sep 24.

PMID:
26401594
17.

Thyrostimulin Regulates Osteoblastic Bone Formation During Early Skeletal Development.

Bassett JH, van der Spek A, Logan JG, Gogakos A, Bagchi-Chakraborty J, Williams AJ, Murphy E, van Zeijl C, Down J, Croucher PI, Boyde A, Boelen A, Williams GR.

Endocrinology. 2015 Sep;156(9):3098-113. doi: 10.1210/en.2014-1943. Epub 2015 May 27. Erratum in: Endocrinology. 2018 Apr 1;159(4):1762.

18.

Contemporary perioperative management of adult familial dysautonomia (Riley-Day syndrome).

Milne A, Mon WY, Down J, Obichere A, Ackland GL.

A A Case Rep. 2015 May 1;4(9):111-3. doi: 10.1213/XAA.0000000000000141.

PMID:
25909774
19.

Experience of propofol sedation in a UK ERCP practice: lessons for service provision.

Joshi D, Paranandi B, El Sayed G, Down J, Johnson GJ, Chapman MH, Pereira SP, Webster GJM.

Frontline Gastroenterol. 2015 Jan;6(1):32-37. doi: 10.1136/flgastro-2014-100495. Epub 2014 Sep 10.

20.

Whole-thorax irradiation induces hypoxic respiratory failure, pleural effusions and cardiac remodeling.

Medhora M, Gao F, Glisch C, Narayanan J, Sharma A, Harmann LM, Lawlor MW, Snyder LA, Fish BL, Down JD, Moulder JE, Strande JL, Jacobs ER.

J Radiat Res. 2015 Mar;56(2):248-60. doi: 10.1093/jrr/rru095. Epub 2014 Nov 3.

21.

Real-time intravital imaging establishes tumor-associated macrophages as the extraskeletal target of bisphosphonate action in cancer.

Junankar S, Shay G, Jurczyluk J, Ali N, Down J, Pocock N, Parker A, Nguyen A, Sun S, Kashemirov B, McKenna CE, Croucher PI, Swarbrick A, Weilbaecher K, Phan TG, Rogers MJ.

Cancer Discov. 2015 Jan;5(1):35-42. doi: 10.1158/2159-8290.CD-14-0621. Epub 2014 Oct 13.

22.

Prostate cancer cells home to bone using a novel in vivo model: modulation by the integrin antagonist GLPG0187.

Reeves KJ, Hurrell JE, Cecchini M, van der Pluijm G, Down JM, Eaton CL, Hamdy F, Clement-Lacroix P, Brown NJ.

Int J Cancer. 2015 Apr 1;136(7):1731-40. doi: 10.1002/ijc.29165. Epub 2014 Sep 4.

23.

Characterization of the dose response relationship for lung injury following acute radiation exposure in three well-established murine strains: developing an interspecies bridge to link animal models with human lung.

Jackson IL, Xu PT, Nguyen G, Down JD, Johnson CS, Katz BP, Hadley CC, Vujaskovic Z.

Health Phys. 2014 Jan;106(1):48-55. doi: 10.1097/HP.0b013e3182a32ccf.

PMID:
24276549
24.

Nuclear targeting of dystroglycan promotes the expression of androgen regulated transcription factors in prostate cancer.

Mathew G, Mitchell A, Down JM, Jacobs LA, Hamdy FC, Eaton C, Rosario DJ, Cross SS, Winder SJ.

Sci Rep. 2013 Sep 30;3:2792. doi: 10.1038/srep02792.

25.

Do variations in mast cell hyperplasia account for differences in radiation-induced lung injury among different mouse strains, rats and nonhuman primates?

Down JD, Medhora M, Jackson IL, Cline JM, Vujaskovic Z.

Radiat Res. 2013 Aug;180(2):216-21. doi: 10.1667/RR3245.1. Epub 2013 Jul 2.

26.

A preclinical rodent model of radiation-induced lung injury for medical countermeasure screening in accordance with the FDA animal rule.

Jackson IL, Xu P, Hadley C, Katz BP, McGurk R, Down JD, Vujaskovic Z.

Health Phys. 2012 Oct;103(4):463-73.

27.

iTRAQ identification of candidate serum biomarkers associated with metastatic progression of human prostate cancer.

Rehman I, Evans CA, Glen A, Cross SS, Eaton CL, Down J, Pesce G, Phillips JT, Yen OS, Thalmann GN, Wright PC, Hamdy FC.

PLoS One. 2012;7(2):e30885. doi: 10.1371/journal.pone.0030885. Epub 2012 Feb 15.

28.

Predicting undergraduates' self-reported engagement in traditional and cyberbullying from attitudes.

Boulton M, Lloyd J, Down J, Marx H.

Cyberpsychol Behav Soc Netw. 2012 Mar;15(3):141-7. doi: 10.1089/cyber.2011.0369. Epub 2012 Feb 3.

PMID:
22304402
29.

Distribution of lentiviral vector integration sites in mice following therapeutic gene transfer to treat β-thalassemia.

Ronen K, Negre O, Roth S, Colomb C, Malani N, Denaro M, Brady T, Fusil F, Gillet-Legrand B, Hehir K, Beuzard Y, Leboulch P, Down JD, Payen E, Bushman FD.

Mol Ther. 2011 Jul;19(7):1273-86. doi: 10.1038/mt.2011.20. Epub 2011 Mar 8.

31.

Transparency makes for good quality health care.

Down JC.

CMAJ. 2011 Jan 11;183(1):84. doi: 10.1503/cmaj.111-2005. No abstract available.

32.

The spleen as a site for hematopoiesis.

Dor FJ, Ramirez ML, Down JD, Cooper DK.

Transplantation. 2010 Nov 15;90(9):1040-1; author reply 1041-2. doi: 10.1097/TP.0b013e3181ef8a7b. No abstract available.

PMID:
21037464
33.

Transfusion independence and HMGA2 activation after gene therapy of human β-thalassaemia.

Cavazzana-Calvo M, Payen E, Negre O, Wang G, Hehir K, Fusil F, Down J, Denaro M, Brady T, Westerman K, Cavallesco R, Gillet-Legrand B, Caccavelli L, Sgarra R, Maouche-Chrétien L, Bernaudin F, Girot R, Dorazio R, Mulder GJ, Polack A, Bank A, Soulier J, Larghero J, Kabbara N, Dalle B, Gourmel B, Socie G, Chrétien S, Cartier N, Aubourg P, Fischer A, Cornetta K, Galacteros F, Beuzard Y, Gluckman E, Bushman F, Hacein-Bey-Abina S, Leboulch P.

Nature. 2010 Sep 16;467(7313):318-22. doi: 10.1038/nature09328.

34.
35.

Hydrogen peroxide vapour decontamination of a critical care unit room used to treat a patient with Lassa fever.

Otter JA, Barnicoat M, Down J, Smyth D, Yezli S, Jeanes A.

J Hosp Infect. 2010 Aug;75(4):335-7. doi: 10.1016/j.jhin.2010.02.025. Epub 2010 May 7. No abstract available.

PMID:
20451295
36.
37.

Early vs late tracheostomy in critical care.

Down J, Williamson W.

Br J Hosp Med (Lond). 2009 Sep;70(9):510-3. Review.

PMID:
19749640
38.

H1N1 pneumonitis treated with intravenous zanamivir.

Kidd IM, Down J, Nastouli E, Shulman R, Grant PR, Howell DC, Singer M.

Lancet. 2009 Sep 19;374(9694):1036. doi: 10.1016/S0140-6736(09)61528-2. Epub 2009 Sep 3. No abstract available.

PMID:
19733390
39.

So you want to be...an anaesthetist.

Down J.

Br J Hosp Med (Lond). 2008 Nov;69(11):M180. No abstract available.

PMID:
19069268
40.

Use of health care guidelines in patients with Down syndrome by family physicians across Canada.

Virji-Babul N, Eichmann A, Kisly D, Down J, Haslam RH.

Paediatr Child Health. 2007 Mar;12(3):179-83.

41.

Posterior reversible encephalopathy syndrome: a report of a case with atypical features.

Pratap JN, Down JF.

Anaesthesia. 2008 Nov;63(11):1245-8. doi: 10.1111/j.1365-2044.2008.05587.x. Epub 2008 Aug 19.

42.

Are we operating as well as we can? Critical care to minimise postoperative mortality and morbidity.

Goldhill DR, Down JF.

Anaesthesia. 2008 Jul;63(7):689-92. doi: 10.1111/j.1365-2044.2008.05611.x. No abstract available.

43.

Molecular characterization of Babesia kiwiensis from the brown kiwi (Apteryx mantelli).

Jefferies R, Down J, McInnes L, Ryan U, Robertson H, Jakob-Hoff R, Irwin P.

J Parasitol. 2008 Apr;94(2):557-60. doi: 10.1645/GE-1344.1.

PMID:
18564765
44.

Distribution of hematopoietic stem cells in the bone marrow according to regional hypoxia.

Parmar K, Mauch P, Vergilio JA, Sackstein R, Down JD.

Proc Natl Acad Sci U S A. 2007 Mar 27;104(13):5431-6. Epub 2007 Mar 20.

45.

Primitive hematopoietic cell populations reside in the spleen: Studies in the pig, baboon, and human.

Dor FJ, Ramirez ML, Parmar K, Altman EL, Huang CA, Down JD, Cooper DK.

Exp Hematol. 2006 Nov;34(11):1573-82.

PMID:
17046577
46.

Therapeutic applications of conotoxins that target the neuronal nicotinic acetylcholine receptor.

Livett BG, Sandall DW, Keays D, Down J, Gayler KR, Satkunanathan N, Khalil Z.

Toxicon. 2006 Dec 1;48(7):810-29. Epub 2006 Jul 15. Review.

PMID:
16979678
47.

So you want to be ... an anaesthetist.

Down J.

Br J Hosp Med (Lond). 2005 Sep;66(9):M39. Review. No abstract available.

PMID:
16200796
48.

Alpha-conotoxin Vc1.1 alleviates neuropathic pain and accelerates functional recovery of injured neurones.

Satkunanathan N, Livett B, Gayler K, Sandall D, Down J, Khalil Z.

Brain Res. 2005 Oct 19;1059(2):149-58. Epub 2005 Sep 22.

PMID:
16182258
49.

Molecular prospecting for drugs from the sea. Isolating therapeutic peptides and proteins from cone snail venom.

Gayler K, Sandall D, Greening D, Keays D, Polidano M, Livett B, Down J, Satkunanathan N, Khalil Z.

IEEE Eng Med Biol Mag. 2005 Mar-Apr;24(2):79-84. No abstract available.

PMID:
15825849
50.

Optimizing the connectivity in disulfide-rich peptides: alpha-conotoxin SII as a case study.

Bingham JP, Broxton NM, Livett BG, Down JG, Jones A, Moczydlowski EG.

Anal Biochem. 2005 Mar 1;338(1):48-61.

PMID:
15707935

Supplemental Content

Support Center