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Items: 4

1.

A germline point mutation in Runx1 uncouples its role in definitive hematopoiesis from differentiation.

Dowdy CR, Frederick D, Zaidi SK, Colby JL, Lian JB, van Wijnen AJ, Gerstein RM, Stein JL, Stein GS.

Exp Hematol. 2013 Nov;41(11):980-991.e1. doi: 10.1016/j.exphem.2013.06.006. Epub 2013 Jun 30.

2.

Epigenetic mechanisms in leukemia.

Zaidi SK, Trombly DJ, Dowdy CR, Lian JB, Stein JL, van Wijnen AJ, Stein GS.

Adv Biol Regul. 2012 Sep;52(3):369-76. doi: 10.1016/j.jbior.2012.05.001. Epub 2012 May 24. Review.

PMID:
22884030
3.

Definitive hematopoiesis requires Runx1 C-terminal-mediated subnuclear targeting and transactivation.

Dowdy CR, Xie R, Frederick D, Hussain S, Zaidi SK, Vradii D, Javed A, Li X, Jones SN, Lian JB, van Wijnen AJ, Stein JL, Stein GS.

Hum Mol Genet. 2010 Mar 15;19(6):1048-57. doi: 10.1093/hmg/ddp568. Epub 2009 Dec 24.

4.

Altered Runx1 subnuclear targeting enhances myeloid cell proliferation and blocks differentiation by activating a miR-24/MKP-7/MAPK network.

Zaidi SK, Dowdy CR, van Wijnen AJ, Lian JB, Raza A, Stein JL, Croce CM, Stein GS.

Cancer Res. 2009 Nov 1;69(21):8249-55. doi: 10.1158/0008-5472.CAN-09-1567. Epub 2009 Oct 13.

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