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Items: 1 to 50 of 349

1.

MEPicides: α,β-Unsaturated Fosmidomycin Analogs as DXR inhibitors against Malaria.

Wang X, Edwards RL, Ball H, Johnson C, Haymond A, Girma M, Manikkam M, Brothers RC, McKay K, Arnett S, Osbourn D, Alvarez S, Boshoff HIM, Meyers MJ, Couch RD, John ARO, Dowd CS.

J Med Chem. 2018 Sep 7. doi: 10.1021/acs.jmedchem.8b01026. [Epub ahead of print]

PMID:
30192536
2.

Revisiting classic MRI findings of venous malformations: Changes in protocols may lead to potential misdiagnosis.

Alexander MD, Hughes N, Cooke DL, Hess CP, Frieden IJ, Phelps AS, Dowd CF.

Neuroradiol J. 2018 Oct;31(5):509-512. doi: 10.1177/1971400918791787. Epub 2018 Aug 9.

PMID:
30089411
3.

An Evaluation of the Pharmacodynamics, Safety, and Tolerability of the Potassium Binder RDX7675.

Pitt B, Zann V, Roe C, Jacobs JW, Davidson JP, Dowd C, Kumaraswamy P, Lin F, Korner P, Blanks RC, Rosenbaum DP.

J Clin Pharmacol. 2018 Apr 12. doi: 10.1002/jcph.1102. [Epub ahead of print]

PMID:
29645278
4.

Flanking the fenestration: circumferential limb-to-limb stent-assisted coiling of a basilar artery fenestration aneurysm.

Morrison J, Alexander MD, Dowd CF, Cooke DL.

J Neurointerv Surg. 2018 Jun;10(6):e12. doi: 10.1136/neurintsurg-2017-013252.rep. Epub 2018 Mar 21.

PMID:
29563213
5.

Can bacterial virulence factors predict antibiotic resistant Helicobacter pylori infection?

Brennan DE, Dowd C, O'Morain C, McNamara D, Smith SM.

World J Gastroenterol. 2018 Mar 7;24(9):971-981. doi: 10.3748/wjg.v24.i9.971.

6.

Improved procedural safety following protocol changes for selective ophthalmic arterial infusion of chemotherapy for treatment of ocular retinoblastoma.

Ammanuel S, Alexander MD, Damato B, Cooke DL, Halbach VV, Amans MR, Dowd CF, Higashida RT, Hetts SW.

Interv Neuroradiol. 2018 Jun;24(3):345-350. doi: 10.1177/1591019918755088. Epub 2018 Feb 13.

PMID:
29436917
7.

The Methylerythritol Phosphate Pathway: Promising Drug Targets in the Fight against Tuberculosis.

Wang X, Dowd CS.

ACS Infect Dis. 2018 Mar 9;4(3):278-290. doi: 10.1021/acsinfecdis.7b00176. Epub 2018 Feb 8.

PMID:
29390176
8.

Estimation of intra-arterial chemotherapy distribution to the retina in pediatric retinoblastoma patients using quantitative digital subtraction angiography.

Kondapavulur S, Cooke DL, Kao A, Amans MR, Alexander M, Darflinger R, Dowd CF, Higashida RT, Damato B, Halbach VV, Matthay KK, Hetts SW.

Interv Neuroradiol. 2018 Apr;24(2):214-219. doi: 10.1177/1591019917749825. Epub 2018 Jan 17.

PMID:
29343147
9.

Trends and Complications in Open Versus Endoscopic Carpal Tunnel Release in Private Payer and Medicare Patient Populations.

Devana SK, Jensen AR, Yamaguchi KT, D'Oro A, Buser Z, Wang JC, Petrigliano FA, Dowd C.

Hand (N Y). 2018 Jan 1:1558944717751196. doi: 10.1177/1558944717751196. [Epub ahead of print]

PMID:
29322873
10.

Technical factors affecting outcomes following endovascular treatment of posterior circulation atherosclerotic lesions.

Alexander MD, Rebhun JM, Hetts SW, Amans MR, Settecase F, Darflinger RJ, Dowd CF, Halbach VV, Higashida RT, Cooke DL.

Surg Neurol Int. 2017 Nov 20;8:284. doi: 10.4103/sni.sni_255_17. eCollection 2017.

11.

A high-throughput screening campaign to identify inhibitors of DXP reductoisomerase (IspC) and MEP cytidylyltransferase (IspD).

Haymond A, Dowdy T, Johny C, Johnson C, Ball H, Dailey A, Schweibenz B, Villarroel K, Young R, Mantooth CJ, Patel T, Bases J, Dowd CS, Couch RD.

Anal Biochem. 2018 Feb 1;542:63-75. doi: 10.1016/j.ab.2017.11.018. Epub 2017 Nov 24.

PMID:
29180070
12.

Improving mechanical thrombectomy time metrics in the angiography suite: Stroke cart, parallel workflows, and conscious sedation.

Settecase F, McCoy DB, Darflinger R, Alexander MD, Cooke DL, Dowd CF, Hetts SW, Higashida RT, Halbach VV, Amans MR.

Interv Neuroradiol. 2018 Apr;24(2):168-177. doi: 10.1177/1591019917742326. Epub 2017 Nov 16.

PMID:
29145742
13.

Non-progressing cancer patients have persistent B cell responses expressing shared antibody paratopes that target public tumor antigens.

DeFalco J, Harbell M, Manning-Bog A, Baia G, Scholz A, Millare B, Sumi M, Zhang D, Chu F, Dowd C, Zuno-Mitchell P, Kim D, Leung Y, Jiang S, Tang X, Williamson KS, Chen X, Carroll SM, Espiritu Santo G, Haaser N, Nguyen N, Giladi E, Minor D, Tan YC, Sokolove JB, Steinman L, Serafini TA, Cavet G, Greenberg NM, Glanville J, Volkmuth W, Emerling DE, Robinson WH.

Clin Immunol. 2018 Feb;187:37-45. doi: 10.1016/j.clim.2017.10.002. Epub 2017 Oct 12.

14.

Flanking the fenestration: circumferential limb-to-limb stent-assisted coiling of a basilar artery fenestration aneurysm.

Morrison J, Alexander MD, Dowd CF, Cooke DL.

BMJ Case Rep. 2017 Oct 13;2017. pii: bcr-2017-013252. doi: 10.1136/neurintsurg-2017-013252.

PMID:
29030497
15.

Pial Artery Supply as an Anatomic Risk Factor for Ischemic Stroke in the Treatment of Intracranial Dural Arteriovenous Fistulas.

Hetts SW, Yen A, Cooke DL, Nelson J, Jolivalt P, Banaga J, Amans MR, Dowd CF, Higashida RT, Lawton MT, Kim H, Halbach VV.

AJNR Am J Neuroradiol. 2017 Dec;38(12):2315-2320. doi: 10.3174/ajnr.A5396. Epub 2017 Sep 28.

PMID:
28970244
16.

Endovascular Biopsy: In Vivo Cerebral Aneurysm Endothelial Cell Sampling and Gene Expression Analysis.

Cooke DL, McCoy DB, Halbach VV, Hetts SW, Amans MR, Dowd CF, Higashida RT, Lawson D, Nelson J, Wang CY, Kim H, Werb Z, McCulloch C, Hashimoto T, Su H, Sun Z.

Transl Stroke Res. 2018 Feb;9(1):20-33. doi: 10.1007/s12975-017-0560-4. Epub 2017 Sep 13.

17.

MEPicides: potent antimalarial prodrugs targeting isoprenoid biosynthesis.

Edwards RL, Brothers RC, Wang X, Maron MI, Ziniel PD, Tsang PS, Kraft TE, Hruz PW, Williamson KC, Dowd CS, John ARO.

Sci Rep. 2017 Aug 21;7(1):8400. doi: 10.1038/s41598-017-07159-y.

18.

Design, synthesis, and evaluation of substituted nicotinamide adenine dinucleotide (NAD+) synthetase inhibitors as potential antitubercular agents.

Wang X, Ahn YM, Lentscher AG, Lister JS, Brothers RC, Kneen MM, Gerratana B, Boshoff HI, Dowd CS.

Bioorg Med Chem Lett. 2017 Sep 15;27(18):4426-4430. doi: 10.1016/j.bmcl.2017.08.012. Epub 2017 Aug 8.

PMID:
28827112
19.

Divergent expression of cytokinin biosynthesis, signaling and catabolism genes underlying differences in feeding sites induced by cyst and root-knot nematodes.

Dowd CD, Chronis D, Radakovic ZS, Siddique S, Schmülling T, Werner T, Kakimoto T, Grundler FMW, Mitchum MG.

Plant J. 2017 Oct;92(2):211-228. doi: 10.1111/tpj.13647. Epub 2017 Aug 31.

PMID:
28746737
20.

Normalization of Congenital Venous Stasis Retinopathy Following Sclerotherapy of a Macrocystic Lymphatic Malformation.

Hirabayashi KE, Kalin-Hajdu E, Bever GJ, Vagefi MR, de Alba Campomanes AG, Cooke DL, Dowd CF, Kersten RC.

Ophthalmic Plast Reconstr Surg. 2018 Jan/Feb;34(1):e19-e21. doi: 10.1097/IOP.0000000000000975.

PMID:
28746255
21.

Interprofessional Precision Care: Coming Together to Improve Outcomes.

Mena-Carrasco F, Pemberton S, Chanmugam A, Dowd C, Rice-Assenza J, Stewart RW.

South Med J. 2016 Nov;109(11):688-689. No abstract available.

PMID:
27812707
22.

Intra-Arterial MR Perfusion Imaging of Meningiomas: Comparison to Digital Subtraction Angiography and Intravenous MR Perfusion Imaging.

Lum MA, Martin AJ, Alexander MD, McCoy DB, Cooke DL, Lillaney P, Moftakhar P, Amans MR, Settecase F, Nicholson A, Dowd CF, Halbach VV, Higashida RT, McDermott MW, Saloner D, Hetts SW.

PLoS One. 2016 Nov 1;11(11):e0163554. doi: 10.1371/journal.pone.0163554. eCollection 2016.

23.

Pediatric intracranial dural arteriovenous fistulas: age-related differences in clinical features, angioarchitecture, and treatment outcomes.

Hetts SW, Moftakhar P, Maluste N, Fullerton HJ, Cooke DL, Amans MR, Dowd CF, Higashida RT, Halbach VV.

J Neurosurg Pediatr. 2016 Nov;18(5):602-610. Epub 2016 Aug 19.

PMID:
27540826
24.

Effects on vessel measurement accuracy and subsequent occlusion after calcium channel blocker infusion during treatment of cerebral aneurysms with the Pipeline embolization device.

Alexander MD, Nicholson AD, Darflinger RJ, Settecase F, Cooke DL, Dowd CF, Amans MR, Higashida RT, Hetts SW, Halbach VV.

Interv Neuroradiol. 2017 Feb;23(1):47-51. doi: 10.1177/1591019916674916. Epub 2016 Oct 27.

25.

Structure-Activity Relationships of the MEPicides: N-Acyl and O-Linked Analogs of FR900098 as Inhibitors of Dxr from Mycobacterium tuberculosis and Yersinia pestis.

San Jose G, Jackson ER, Haymond A, Johny C, Edwards RL, Wang X, Brothers RC, Edelstein EK, Odom AR, Boshoff HI, Couch RD, Dowd CS.

ACS Infect Dis. 2016 Dec 9;2(12):923-935. Epub 2016 Oct 12.

26.

Targeting an Aromatic Hotspot in Plasmodium falciparum 1-Deoxy-d-xylulose-5-phosphate Reductoisomerase with β-Arylpropyl Analogues of Fosmidomycin.

Sooriyaarachchi S, Chofor R, Risseeuw MD, Bergfors T, Pouyez J, Dowd CS, Maes L, Wouters J, Jones TA, Van Calenbergh S, Mowbray SL.

ChemMedChem. 2016 Sep 20;11(18):2024-36. doi: 10.1002/cmdc.201600249. Epub 2016 Aug 3.

PMID:
27487410
27.

The Cystic Fibrosis Foundation Patient Registry. Design and Methods of a National Observational Disease Registry.

Knapp EA, Fink AK, Goss CH, Sewall A, Ostrenga J, Dowd C, Elbert A, Petren KM, Marshall BC.

Ann Am Thorac Soc. 2016 Jul;13(7):1173-9. doi: 10.1513/AnnalsATS.201511-781OC.

PMID:
27078236
28.

Endovascular biopsy: Strategy for analyzing gene expression profiles of individual endothelial cells obtained from human vessels.

Sun Z, Lawson DA, Sinclair E, Wang CY, Lai MD, Hetts SW, Higashida RT, Dowd CF, Halbach VV, Werb Z, Su H, Cooke DL.

Biotechnol Rep (Amst). 2015 Sep;7:157-165. Epub 2015 Aug 1.

29.

Onyx embolization of an intraosseous pseudoaneurysm of the middle meningeal artery in a patient with meningiomatosis, McCune-Albright syndrome, and gray platelet syndrome.

Settecase F, Nicholson AD, Amans MR, Higashida RT, Halbach VV, Cooke DL, Dowd CF, Hetts SW.

J Neurosurg Pediatr. 2016 Mar;17(3):324-9. doi: 10.3171/2015.9.PEDS15267. Epub 2015 Nov 20.

PMID:
26588455
30.

Superselective Intra-Arterial Ethanol Sclerotherapy of Feeding Artery and Nidal Aneurysms in Ruptured Cerebral Arteriovenous Malformations.

Settecase F, Hetts SW, Nicholson AD, Amans MR, Cooke DL, Dowd CF, Higashida RT, Halbach VV.

AJNR Am J Neuroradiol. 2016 Apr;37(4):692-7. doi: 10.3174/ajnr.A4584. Epub 2015 Nov 12.

31.

Spontaneous retroclival hematoma: a case series.

Narvid J, Amans MR, Cooke DL, Hetts SW, Dillon WP, Higashida RT, Dowd CF, Halbach VV.

J Neurosurg. 2016 Mar;124(3):716-9. doi: 10.3171/2015.2.JNS142221. Epub 2015 Aug 7.

PMID:
26252463
32.

Progressive versus Nonprogressive Intracranial Dural Arteriovenous Fistulas: Characteristics and Outcomes.

Hetts SW, Tsai T, Cooke DL, Amans MR, Settecase F, Moftakhar P, Dowd CF, Higashida RT, Lawton MT, Halbach VV.

AJNR Am J Neuroradiol. 2015 Oct;36(10):1912-9. doi: 10.3174/ajnr.A4391. Epub 2015 Jul 23.

33.

MRI phenotypes of localized intravascular coagulopathy in venous malformations.

Koo KS, Dowd CF, Mathes EF, Rosbe KW, Hoffman WY, Frieden IJ, Hess CP.

Pediatr Radiol. 2015 Oct;45(11):1690-5. doi: 10.1007/s00247-015-3389-6. Epub 2015 Jul 5.

PMID:
26143286
34.

Volume-staged radiosurgery for large arteriovenous malformations: an evolving paradigm.

Seymour ZA, Sneed PK, Gupta N, Lawton MT, Molinaro AM, Young W, Dowd CF, Halbach VV, Higashida RT, McDermott MW.

J Neurosurg. 2016 Jan;124(1):163-74. doi: 10.3171/2014.12.JNS141308. Epub 2015 Jul 3.

35.

Endovascular biopsy: Technical feasibility of novel endothelial cell harvesting devices assessed in a rabbit aneurysm model.

Cooke DL, Bauer D, Sun Z, Stillson C, Nelson J, Barry D, Hetts SW, Higashida RT, Dowd CF, Halbach VV, Su H, Saeed MM.

Interv Neuroradiol. 2015 Feb;21(1):120-8. doi: 10.15274/INR-2014-10103.

36.

Atypical MRI features in soft-tissue arteriovenous malformation: a novel imaging appearance with radiologic-pathologic correlation.

Patel AS, Schulman JM, Ruben BS, Hoffman WY, Dowd CF, Frieden IJ, Hess CP.

Pediatr Radiol. 2015 Sep;45(10):1515-21. doi: 10.1007/s00247-015-3359-z. Epub 2015 Apr 28.

37.

Lesion location, stability, and pretreatment management: factors affecting outcomes of endovascular treatment for vertebrobasilar atherosclerosis.

Alexander MD, Rebhun JM, Hetts SW, Kim AS, Nelson J, Kim H, Amans MR, Settecase F, Dowd CF, Halbach VV, Higashida RT, Cooke DL.

J Neurointerv Surg. 2016 May;8(5):466-70. doi: 10.1136/neurintsurg-2014-011633. Epub 2015 Mar 20.

PMID:
25795438
38.

Synthesis and bioactivity of β-substituted fosmidomycin analogues targeting 1-deoxy-D-xylulose-5-phosphate reductoisomerase.

Chofor R, Sooriyaarachchi S, Risseeuw MD, Bergfors T, Pouyez J, Johny C, Haymond A, Everaert A, Dowd CS, Maes L, Coenye T, Alex A, Couch RD, Jones TA, Wouters J, Mowbray SL, Van Calenbergh S.

J Med Chem. 2015 Apr 9;58(7):2988-3001. doi: 10.1021/jm5014264. Epub 2015 Mar 31.

PMID:
25781377
39.

Association between Venous Angioarchitectural Features of Sporadic Brain Arteriovenous Malformations and Intracranial Hemorrhage.

Alexander MD, Cooke DL, Nelson J, Guo DE, Dowd CF, Higashida RT, Halbach VV, Lawton MT, Kim H, Hetts SW.

AJNR Am J Neuroradiol. 2015 May;36(5):949-52. doi: 10.3174/ajnr.A4224. Epub 2015 Jan 29.

40.

Extent of collateralization predicting symptomatic cerebral vasospasm among pediatric patients: correlations among angiography, transcranial Doppler ultrasonography, and clinical findings.

Moftakhar P, Cooke DL, Fullerton HJ, Ko NU, Amans MR, Narvid JA, Dowd CF, Higashida RT, Halbach VV, Hetts SW.

J Neurosurg Pediatr. 2015 Mar;15(3):282-90. doi: 10.3171/2014.9.PEDS14313. Epub 2015 Jan 2.

PMID:
25555113
41.

Endothelial cell high-enrichment from endovascular biopsy sample by laser capture microdissection and fluorescence activated cell sorting.

Sun Z, Su H, Long B, Sinclair E, Hetts SW, Higashida RT, Dowd CF, Halbach VV, Cooke DL.

J Biotechnol. 2014 Dec 20;192 Pt A:34-9.

42.

Lesion stability characteristics outperform degree of stenosis in predicting outcomes following stenting for symptomatic intracranial atherosclerosis.

Alexander MD, Cooke DL, Meyers PM, Amans MR, Dowd CF, Halbach VV, Higashida RT, Hetts SW.

J Neurointerv Surg. 2016 Jan;8(1):19-23. doi: 10.1136/neurintsurg-2014-011482. Epub 2014 Nov 21.

PMID:
25416828
43.

Texting and walking: effect of environmental setting and task prioritization on dual-task interference in healthy young adults.

Plummer P, Apple S, Dowd C, Keith E.

Gait Posture. 2015 Jan;41(1):46-51. doi: 10.1016/j.gaitpost.2014.08.007. Epub 2014 Aug 20.

PMID:
25193796
44.

Kinetic characterization and allosteric inhibition of the Yersinia pestis 1-deoxy-D-xylulose 5-phosphate reductoisomerase (MEP synthase).

Haymond A, Johny C, Dowdy T, Schweibenz B, Villarroel K, Young R, Mantooth CJ, Patel T, Bases J, San Jose G, Jackson ER, Dowd CS, Couch RD.

PLoS One. 2014 Aug 29;9(8):e106243. doi: 10.1371/journal.pone.0106243. eCollection 2014.

45.

Aspirin therapy in venous malformation: a retrospective cohort study of benefits, side effects, and patient experiences.

Nguyen JT, Koerper MA, Hess CP, Dowd CF, Hoffman WY, Dickman M, Frieden IJ.

Pediatr Dermatol. 2014 Sep-Oct;31(5):556-60. doi: 10.1111/pde.12373. Epub 2014 Jul 21.

PMID:
25040175
46.

Cerebral arterial fenestrations.

Cooke DL, Stout CE, Kim WT, Kansagra AP, Yu JP, Gu A, Jewell NP, Hetts SW, Higashida RT, Dowd CF, Halbach VV.

Interv Neuroradiol. 2014 May-Jun;20(3):261-74. doi: 10.15274/NRJ-2014-10027. Epub 2014 Jun 17.

47.

Some Nigerian anti-tuberculosis ethnomedicines: a preliminary efficacy assessment.

Ibekwe NN, Nvau JB, Oladosu PO, Usman AM, Ibrahim K, Boshoff HI, Dowd CS, Orisadipe AT, Aiyelaagbe O, Adesomoju AA, Barry CE 3rd, Okogun JI; collaboration with 73 Visited Herbalists.

J Ethnopharmacol. 2014 Aug 8;155(1):524-32. doi: 10.1016/j.jep.2014.05.059. Epub 2014 Jun 6.

48.

Radiological and clinical features of vein of Galen malformations.

Chow ML, Cooke DL, Fullerton HJ, Amans MR, Narvid J, Dowd CF, Higashida RT, Halbach VV, Hetts SW.

J Neurointerv Surg. 2015 Jun;7(6):443-8. doi: 10.1136/neurintsurg-2013-011005. Epub 2014 Apr 30.

PMID:
24789593
49.

Symptom differences and pretreatment asymptomatic interval affect outcomes of stenting for intracranial atherosclerotic disease.

Alexander MD, Meyers PM, English JD, Stradford TR, Sung S, Smith WS, Halbach VV, Higashida RT, Dowd CF, Cooke DL, Hetts SW.

AJNR Am J Neuroradiol. 2014 Jun;35(6):1157-62. doi: 10.3174/ajnr.A3836. Epub 2014 Mar 27.

50.

Influence of patient age on angioarchitecture of brain arteriovenous malformations.

Hetts SW, Cooke DL, Nelson J, Gupta N, Fullerton H, Amans MR, Narvid JA, Moftakhar P, McSwain H, Dowd CF, Higashida RT, Halbach VV, Lawton MT, Kim H.

AJNR Am J Neuroradiol. 2014 Jul;35(7):1376-80. doi: 10.3174/ajnr.A3886. Epub 2014 Mar 13.

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