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Items: 17

1.

Applications of CRISPR genome editing technology in drug target identification and validation.

Lu Q, Livi GP, Modha S, Yusa K, Macarrón R, Dow DJ.

Expert Opin Drug Discov. 2017 Jun;12(6):541-552. doi: 10.1080/17460441.2017.1317244. Epub 2017 Apr 23. Review.

PMID:
28388235
2.

In Vivo Tracking of Human Hematopoiesis Reveals Patterns of Clonal Dynamics during Early and Steady-State Reconstitution Phases.

Biasco L, Pellin D, Scala S, Dionisio F, Basso-Ricci L, Leonardelli L, Scaramuzza S, Baricordi C, Ferrua F, Cicalese MP, Giannelli S, Neduva V, Dow DJ, Schmidt M, Von Kalle C, Roncarolo MG, Ciceri F, Vicard P, Wit E, Di Serio C, Naldini L, Aiuti A.

Cell Stem Cell. 2016 Jul 7;19(1):107-19. doi: 10.1016/j.stem.2016.04.016. Epub 2016 May 26.

3.

Lentiviral hematopoietic stem cell gene therapy benefits metachromatic leukodystrophy.

Biffi A, Montini E, Lorioli L, Cesani M, Fumagalli F, Plati T, Baldoli C, Martino S, Calabria A, Canale S, Benedicenti F, Vallanti G, Biasco L, Leo S, Kabbara N, Zanetti G, Rizzo WB, Mehta NA, Cicalese MP, Casiraghi M, Boelens JJ, Del Carro U, Dow DJ, Schmidt M, Assanelli A, Neduva V, Di Serio C, Stupka E, Gardner J, von Kalle C, Bordignon C, Ciceri F, Rovelli A, Roncarolo MG, Aiuti A, Sessa M, Naldini L.

Science. 2013 Aug 23;341(6148):1233158. doi: 10.1126/science.1233158. Epub 2013 Jul 11.

4.

Lentiviral hematopoietic stem cell gene therapy in patients with Wiskott-Aldrich syndrome.

Aiuti A, Biasco L, Scaramuzza S, Ferrua F, Cicalese MP, Baricordi C, Dionisio F, Calabria A, Giannelli S, Castiello MC, Bosticardo M, Evangelio C, Assanelli A, Casiraghi M, Di Nunzio S, Callegaro L, Benati C, Rizzardi P, Pellin D, Di Serio C, Schmidt M, Von Kalle C, Gardner J, Mehta N, Neduva V, Dow DJ, Galy A, Miniero R, Finocchi A, Metin A, Banerjee PP, Orange JS, Galimberti S, Valsecchi MG, Biffi A, Montini E, Villa A, Ciceri F, Roncarolo MG, Naldini L.

Science. 2013 Aug 23;341(6148):1233151. doi: 10.1126/science.1233151. Epub 2013 Jul 11.

5.

Tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide and N-benzyl-6',7'-dihydrospiro[piperidine-4,4'-thieno[3,2-c]pyran] analogues with bactericidal efficacy against Mycobacterium tuberculosis targeting MmpL3.

Remuiñán MJ, Pérez-Herrán E, Rullás J, Alemparte C, Martínez-Hoyos M, Dow DJ, Afari J, Mehta N, Esquivias J, Jiménez E, Ortega-Muro F, Fraile-Gabaldón MT, Spivey VL, Loman NJ, Pallen MJ, Constantinidou C, Minick DJ, Cacho M, Rebollo-López MJ, González C, Sousa V, Angulo-Barturen I, Mendoza-Losana A, Barros D, Besra GS, Ballell L, Cammack N.

PLoS One. 2013 Apr 17;8(4):e60933. doi: 10.1371/journal.pone.0060933. Print 2013.

6.

The application of next-generation sequencing technologies to drug discovery and development.

Woollard PM, Mehta NA, Vamathevan JJ, Van Horn S, Bonde BK, Dow DJ.

Drug Discov Today. 2011 Jun;16(11-12):512-9. doi: 10.1016/j.drudis.2011.03.006. Epub 2011 Apr 1. Review.

PMID:
21440664
7.

ADAMTSL3 as a candidate gene for schizophrenia: gene sequencing and ultra-high density association analysis by imputation.

Dow DJ, Huxley-Jones J, Hall JM, Francks C, Maycox PR, Kew JN, Gloger IS, Mehta NA, Kelly FM, Muglia P, Breen G, Jugurnauth S, Pederoso I, St Clair D, Rujescu D, Barnes MR.

Schizophr Res. 2011 Apr;127(1-3):28-34. doi: 10.1016/j.schres.2010.12.009. Epub 2011 Jan 15.

PMID:
21239144
8.

CCR2 and coronary artery disease: a woscops substudy.

Dow DJ, McMahon AD, Gray IC, Packard CJ, Groot PH.

BMC Res Notes. 2010 Feb 2;3:31. doi: 10.1186/1756-0500-3-31.

9.

Genetic variations in HLA-B region and hypersensitivity reactions to abacavir.

Hetherington S, Hughes AR, Mosteller M, Shortino D, Baker KL, Spreen W, Lai E, Davies K, Handley A, Dow DJ, Fling ME, Stocum M, Bowman C, Thurmond LM, Roses AD.

Lancet. 2002 Mar 30;359(9312):1121-2.

PMID:
11943262
10.

Prenatal diagnosis of tuberous sclerosis with intracerebral signs at 14 weeks' gestation.

Brackley KJ, Farndon PA, Weaver JB, Dow DJ, Chapman S, Kilby MD.

Prenat Diagn. 1999 Jun;19(6):575-9.

PMID:
10416977
11.

Alpha-2 macroglobulin polymorphism and Alzheimer disease risk in the UK.

Dow DJ, Lindsey N, Cairns NJ, Brayne C, Robinson D, Huppert FA, Paykel ES, Xuereb J, Wilcock G, Whittaker JL, Rubinsztein DC.

Nat Genet. 1999 May;22(1):16-7; author reply 21-2. No abstract available.

PMID:
10319853
12.

Instability of normal (CTG)n alleles in the DM kinase gene.

Dow DJ, Rubinsztein DC, Yates JR, Barton DE, Ferguson-Smith MA.

J Med Genet. 1997 Oct;34(10):871-3.

13.

A study of FRAXE in mentally retarded individuals referred for fragile X syndrome (FRAXA) testing in the United Kingdom.

Knight SJ, Ritchie RJ, Chakrabarti L, Cross G, Taylor GR, Mueller RF, Hurst J, Paterson J, Yates JR, Dow DJ, Davies KE.

Am J Hum Genet. 1996 May;58(5):906-13.

14.

Electroencephalographic changes in migraine; review of 51 cases.

DOW DJ, WHITTY CW.

Lancet. 1947 Jul 12;2(6463):52-4. No abstract available.

PMID:
20252058
15.

An investigation of simple methods for diagnosing vitamin a deficiency by measurements of dark adaptation.

Dow DJ, Steven DM.

J Physiol. 1941 Nov 28;100(3):256-62. No abstract available.

16.

A COMPARATIVE STUDY OF CHEST RADIOGRAMS AND THE MANTOUX TEST IN CHILDREN.

Dow DJ, Lloyd WE.

Br Med J. 1932 Apr 16;1(3719):701-3. No abstract available.

17.

THE INCIDENCE OF TUBERCULOUS INFECTION AND ITS RELATION TO CONTAGION IN CHILDREN UNDER 15.

Dow DJ, Lloyd WE.

Br Med J. 1931 Aug 1;2(3682):183-6. No abstract available.

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