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Items: 37

1.

Analysis of Cysteine Post Translational Modifications Using Organic Mercury Resin.

Doulias PT, Gould NS.

Curr Protoc Protein Sci. 2018 Nov;94(1):e69. doi: 10.1002/cpps.69. Epub 2018 Oct 3.

PMID:
30281936
2.

Oral nitrite restores age-dependent phenotypes in eNOS-null mice.

Tenopoulou M, Doulias PT, Nakamoto K, Berrios K, Zura G, Li C, Faust M, Yakovishina V, Evans P, Tan L, Bennett MJ, Snyder NW, Quinn WJ 3rd, Baur JA, Atochin DN, Huang PL, Ischiropoulos H.

JCI Insight. 2018 Aug 23;3(16). pii: 122156. doi: 10.1172/jci.insight.122156. eCollection 2018 Aug 23.

3.

Nitric Oxide Disrupts Zinc Homeostasis in Salmonella enterica Serovar Typhimurium.

Frawley ER, Karlinsey JE, Singhal A, Libby SJ, Doulias PT, Ischiropoulos H, Fang FC.

MBio. 2018 Aug 14;9(4). pii: e01040-18. doi: 10.1128/mBio.01040-18.

4.

Diet-Induced Circadian Enhancer Remodeling Synchronizes Opposing Hepatic Lipid Metabolic Processes.

Guan D, Xiong Y, Borck PC, Jang C, Doulias PT, Papazyan R, Fang B, Jiang C, Zhang Y, Briggs ER, Hu W, Steger D, Ischiropoulos H, Rabinowitz JD, Lazar MA.

Cell. 2018 Aug 9;174(4):831-842.e12. doi: 10.1016/j.cell.2018.06.031. Epub 2018 Jul 26.

PMID:
30057115
5.

Host Nitric Oxide Disrupts Microbial Cell-to-Cell Communication to Inhibit Staphylococcal Virulence.

Urbano R, Karlinsey JE, Libby SJ, Doulias PT, Ischiropoulos H, Warheit-Niemi HI, Liggitt DH, Horswill AR, Fang FC.

Cell Host Microbe. 2018 May 9;23(5):594-606.e7. doi: 10.1016/j.chom.2018.04.001.

6.

Hepatic metal ion transporter ZIP8 regulates manganese homeostasis and manganese-dependent enzyme activity.

Lin W, Vann DR, Doulias PT, Wang T, Landesberg G, Li X, Ricciotti E, Scalia R, He M, Hand NJ, Rader DJ.

J Clin Invest. 2017 Jun 1;127(6):2407-2417. doi: 10.1172/JCI90896. Epub 2017 May 8.

7.

RhoA S-nitrosylation as a regulatory mechanism influencing endothelial barrier function in response to G+-bacterial toxins.

Chen F, Wang Y, Rafikov R, Haigh S, Zhi WB, Kumar S, Doulias PT, Rafikova O, Pillich H, Chakraborty T, Lucas R, Verin AD, Catravas JD, She JX, Black SM, Fulton DJR.

Biochem Pharmacol. 2017 Mar 1;127:34-45. doi: 10.1016/j.bcp.2016.12.014. Epub 2016 Dec 22.

8.

Pharmacokinetics and Pharmacodynamics of Inorganic Nitrate in Heart Failure With Preserved Ejection Fraction.

Zamani P, Tan V, Soto-Calderon H, Beraun M, Brandimarto JA, Trieu L, Varakantam S, Doulias PT, Townsend RR, Chittams J, Margulies KB, Cappola TP, Poole DC, Ischiropoulos H, Chirinos JA.

Circ Res. 2017 Mar 31;120(7):1151-1161. doi: 10.1161/CIRCRESAHA.116.309832. Epub 2016 Dec 7.

9.

Heart Failure, Left Ventricular Remodeling, and Circulating Nitric Oxide Metabolites.

Chirinos JA, Akers SR, Trieu L, Ischiropoulos H, Doulias PT, Tariq A, Vasim I, Koppula MR, Syed AA, Soto-Calderon H, Townsend RR, Cappola TP, Margulies KB, Zamani P.

J Am Heart Assoc. 2016 Oct 14;5(10). pii: e004133. Erratum in: J Am Heart Assoc. 2017 Feb 14;6(2):.

10.

Effect of Heart Failure With Preserved Ejection Fraction on Nitric Oxide Metabolites.

Zamani P, French B, Brandimarto JA, Doulias PT, Javaheri A, Chirinos JA, Margulies KB, Townsend RR, Sweitzer NK, Fang JC, Ischiropoulos H, Cappola TP.

Am J Cardiol. 2016 Dec 15;118(12):1855-1860. doi: 10.1016/j.amjcard.2016.08.077. Epub 2016 Sep 15.

11.

S-Nitrosylation of Calcium-Handling Proteins in Cardiac Adrenergic Signaling and Hypertrophy.

Irie T, Sips PY, Kai S, Kida K, Ikeda K, Hirai S, Moazzami K, Jiramongkolchai P, Bloch DB, Doulias PT, Armoundas AA, Kaneki M, Ischiropoulos H, Kranias E, Bloch KD, Stamler JS, Ichinose F.

Circ Res. 2015 Oct 9;117(9):793-803. doi: 10.1161/CIRCRESAHA.115.307157. Epub 2015 Aug 10.

12.

Regulation of brain glutamate metabolism by nitric oxide and S-nitrosylation.

Raju K, Doulias PT, Evans P, Krizman EN, Jackson JG, Horyn O, Daikhin Y, Nissim I, Yudkoff M, Nissim I, Sharp KA, Robinson MB, Ischiropoulos H.

Sci Signal. 2015 Jul 7;8(384):ra68. doi: 10.1126/scisignal.aaa4312.

13.

Strategies for correcting very long chain acyl-CoA dehydrogenase deficiency.

Tenopoulou M, Chen J, Bastin J, Bennett MJ, Ischiropoulos H, Doulias PT.

J Biol Chem. 2015 Apr 17;290(16):10486-94. doi: 10.1074/jbc.M114.635102. Epub 2015 Mar 3.

14.

Effect of inorganic nitrate on exercise capacity in heart failure with preserved ejection fraction.

Zamani P, Rawat D, Shiva-Kumar P, Geraci S, Bhuva R, Konda P, Doulias PT, Ischiropoulos H, Townsend RR, Margulies KB, Cappola TP, Poole DC, Chirinos JA.

Circulation. 2015 Jan 27;131(4):371-80; discussion 380. doi: 10.1161/CIRCULATIONAHA.114.012957. Epub 2014 Dec 22.

15.

Neutralizing Th2 inflammation in neonatal islets prevents β-cell failure in adult IUGR rats.

Jaeckle Santos LJ, Li C, Doulias PT, Ischiropoulos H, Worthen GS, Simmons RA.

Diabetes. 2014 May;63(5):1672-84. doi: 10.2337/db13-1226. Epub 2014 Jan 9.

16.

The 4-cysteine zinc-finger motif of the RNA polymerase regulator DksA serves as a thiol switch for sensing oxidative and nitrosative stress.

Henard CA, Tapscott T, Crawford MA, Husain M, Doulias PT, Porwollik S, Liu L, McClelland M, Ischiropoulos H, Vázquez-Torres A.

Mol Microbiol. 2014 Feb;91(4):790-804. doi: 10.1111/mmi.12498. Epub 2014 Jan 7.

17.

Protein microarray characterization of the S-nitrosoproteome.

Lee YI, Giovinazzo D, Kang HC, Lee Y, Jeong JS, Doulias PT, Xie Z, Hu J, Ghasemi M, Ischiropoulos H, Qian J, Zhu H, Blackshaw S, Dawson VL, Dawson TM.

Mol Cell Proteomics. 2014 Jan;13(1):63-72. doi: 10.1074/mcp.M113.032235. Epub 2013 Oct 8.

18.

Regulation of protein function and signaling by reversible cysteine S-nitrosylation.

Gould N, Doulias PT, Tenopoulou M, Raju K, Ischiropoulos H.

J Biol Chem. 2013 Sep 13;288(37):26473-9. doi: 10.1074/jbc.R113.460261. Epub 2013 Jul 16. Review.

19.

Site specific identification of endogenous S-nitrosocysteine proteomes.

Doulias PT, Tenopoulou M, Raju K, Spruce LA, Seeholzer SH, Ischiropoulos H.

J Proteomics. 2013 Oct 30;92:195-203. doi: 10.1016/j.jprot.2013.05.033. Epub 2013 Jun 5.

20.

Nitric oxide regulates mitochondrial fatty acid metabolism through reversible protein S-nitrosylation.

Doulias PT, Tenopoulou M, Greene JL, Raju K, Ischiropoulos H.

Sci Signal. 2013 Jan 1;6(256):rs1. doi: 10.1126/scisignal.2003252.

21.

Mass spectrometry-based identification of S-nitrosocysteine in vivo using organic mercury assisted enrichment.

Doulias PT, Raju K, Greene JL, Tenopoulou M, Ischiropoulos H.

Methods. 2013 Aug 1;62(2):165-70. doi: 10.1016/j.ymeth.2012.10.009. Epub 2012 Oct 29. Review.

22.

Immunoglobulins against tyrosine-nitrated epitopes in coronary artery disease.

Thomson L, Tenopoulou M, Lightfoot R, Tsika E, Parastatidis I, Martinez M, Greco TM, Doulias PT, Wu Y, Tang WH, Hazen SL, Ischiropoulos H.

Circulation. 2012 Nov 13;126(20):2392-401. doi: 10.1161/CIRCULATIONAHA.112.103796. Epub 2012 Oct 18.

23.

T2R38 taste receptor polymorphisms underlie susceptibility to upper respiratory infection.

Lee RJ, Xiong G, Kofonow JM, Chen B, Lysenko A, Jiang P, Abraham V, Doghramji L, Adappa ND, Palmer JN, Kennedy DW, Beauchamp GK, Doulias PT, Ischiropoulos H, Kreindler JL, Reed DR, Cohen NA.

J Clin Invest. 2012 Nov;122(11):4145-59. doi: 10.1172/JCI64240. Epub 2012 Oct 8.

24.

Strategies and tools to explore protein S-nitrosylation.

Raju K, Doulias PT, Tenopoulou M, Greene JL, Ischiropoulos H.

Biochim Biophys Acta. 2012 Jun;1820(6):684-8. doi: 10.1016/j.bbagen.2011.05.009. Epub 2011 May 30. Review.

25.

Lymphocyte development requires S-nitrosoglutathione reductase.

Yang Z, Wang ZE, Doulias PT, Wei W, Ischiropoulos H, Locksley RM, Liu L.

J Immunol. 2010 Dec 1;185(11):6664-9. doi: 10.4049/jimmunol.1000080. Epub 2010 Oct 27.

26.

Structural profiling of endogenous S-nitrosocysteine residues reveals unique features that accommodate diverse mechanisms for protein S-nitrosylation.

Doulias PT, Greene JL, Greco TM, Tenopoulou M, Seeholzer SH, Dunbrack RL, Ischiropoulos H.

Proc Natl Acad Sci U S A. 2010 Sep 28;107(39):16958-63. doi: 10.1073/pnas.1008036107. Epub 2010 Sep 13.

27.

Flow cytometric estimation of 'labile iron pool' in human white blood cells reveals a positive association with ageing.

Doulias PT, Vlachou C, Boudouri C, Kanavaros P, Siamopoulos KC, Galaris D.

Free Radic Res. 2008 Mar;42(3):253-9. doi: 10.1080/10715760801911649.

PMID:
18344120
28.

Involvement of heat shock protein-70 in the mechanism of hydrogen peroxide-induced DNA damage: the role of lysosomes and iron.

Doulias PT, Kotoglou P, Tenopoulou M, Keramisanou D, Tzavaras T, Brunk U, Galaris D, Angelidis C.

Free Radic Biol Med. 2007 Feb 15;42(4):567-77. Epub 2006 Nov 30.

PMID:
17275689
29.

Does the calcein-AM method assay the total cellular 'labile iron pool' or only a fraction of it?

Tenopoulou M, Kurz T, Doulias PT, Galaris D, Brunk UT.

Biochem J. 2007 Apr 15;403(2):261-6.

30.

DNA protecting and genotoxic effects of olive oil related components in cells exposed to hydrogen peroxide.

Nousis L, Doulias PT, Aligiannis N, Bazios D, Agalias A, Galaris D, Mitakou S.

Free Radic Res. 2005 Jul;39(7):787-95.

PMID:
16036359
31.

Protection by tropolones against H2O2-induced DNA damage and apoptosis in cultured Jurkat cells.

Doulias PT, Nousis L, Zhu BZ, Frei B, Galaris D.

Free Radic Res. 2005 Feb;39(2):125-35.

PMID:
15763960
32.

Role of compartmentalized redox-active iron in hydrogen peroxide-induced DNA damage and apoptosis.

Tenopoulou M, Doulias PT, Barbouti A, Brunk U, Galaris D.

Biochem J. 2005 May 1;387(Pt 3):703-10.

33.
34.

DNA damage and apoptosis in hydrogen peroxide-exposed Jurkat cells: bolus addition versus continuous generation of H(2)O(2).

Barbouti A, Doulias PT, Nousis L, Tenopoulou M, Galaris D.

Free Radic Biol Med. 2002 Sep 1;33(5):691-702.

PMID:
12208356
35.

Intracellular iron, but not copper, plays a critical role in hydrogen peroxide-induced DNA damage.

Barbouti A, Doulias PT, Zhu BZ, Frei B, Galaris D.

Free Radic Biol Med. 2001 Aug 15;31(4):490-8.

PMID:
11498282
36.

Trimetazidine protects low-density lipoproteins from oxidation and cultured cells exposed to H(2)O(2) from DNA damage.

Tselepis A, Doulias P, Lourida E, Glantzounis G, Tsimoyiannis E, Galaris D.

Free Radic Biol Med. 2001 Jun 15;30(12):1357-64.

PMID:
11390180
37.

SIN-1-induced DNA damage in isolated human peripheral blood lymphocytes as assessed by single cell gel electrophoresis (comet assay).

Doulias PT, Barbouti A, Galaris D, Ischiropoulos H.

Free Radic Biol Med. 2001 Mar 15;30(6):679-85.

PMID:
11295366

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