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Items: 1 to 50 of 302

1.

Inter-subunit interactions drive divergent dynamics in mammalian and Plasmodium actin filaments.

Douglas RG, Nandekar P, Aktories JE, Kumar H, Weber R, Sattler JM, Singer M, Lepper S, Sadiq SK, Wade RC, Frischknecht F.

PLoS Biol. 2018 Jul 16;16(7):e2005345. doi: 10.1371/journal.pbio.2005345. eCollection 2018 Jul.

2.

Our experience of the necessity of adenoidectomy or adenotonsillectomy at the time of ventilation tube insertion in 11 941 children with middle ear effusion.

Johnston J, Kinzett-Carran G, Mahadevan M, Douglas RG.

Clin Otolaryngol. 2018 Mar 30. doi: 10.1111/coa.13110. [Epub ahead of print] No abstract available.

PMID:
29600829
3.

The effect of medical treatments on the bacterial microbiome in patients with chronic rhinosinusitis: a pilot study.

Jain R, Hoggard M, Zoing M, Jiang Y, Biswas K, Taylor MW, Douglas RG.

Int Forum Allergy Rhinol. 2018 Mar 8. doi: 10.1002/alr.22110. [Epub ahead of print]

PMID:
29517178
4.

Peritonsillar abscess: A retrospective case series of 1773 patients.

Johnston J, Stretton M, Mahadevan M, Douglas RG.

Clin Otolaryngol. 2018 Jun;43(3):940-944. doi: 10.1111/coa.13070. Epub 2018 Feb 19. No abstract available.

PMID:
29377585
5.

The sinonasal microbiota, neural signaling, and depression in chronic rhinosinusitis.

Hoggard M, Nocera A, Biswas K, Taylor MW, Douglas RG, Bleier BS.

Int Forum Allergy Rhinol. 2018 Mar;8(3):394-405. doi: 10.1002/alr.22074. Epub 2017 Dec 26.

PMID:
29278464
6.

Differentially Regulated Host Proteins Associated with Chronic Rhinosinusitis Are Correlated with the Sinonasal Microbiome.

Biswas K, Wagner Mackenzie B, Waldvogel-Thurlow S, Middleditch M, Jullig M, Zoing M, Taylor MW, Douglas RG.

Front Cell Infect Microbiol. 2017 Dec 6;7:504. doi: 10.3389/fcimb.2017.00504. eCollection 2017.

7.

Incidence and factors associated with revision adenoidectomy: A retrospective study.

Johnston J, Mahadevan M, Douglas RG.

Int J Pediatr Otorhinolaryngol. 2017 Dec;103:125-128. doi: 10.1016/j.ijporl.2017.10.023. Epub 2017 Oct 18.

PMID:
29224752
8.

How does sinus surgery affect topical irrigation distribution?

de Paiva Leite SH, Douglas RG.

Curr Opin Otolaryngol Head Neck Surg. 2018 Feb;26(1):21-26. doi: 10.1097/MOO.0000000000000429.

PMID:
29176480
9.

Moving beyond descriptions of diversity: clinical and research implications of bacterial imbalance in chronic rhinosinusitis.

Wagner Mackenzie B, Waite DW, Hoggard M, Taylor MW, Biswas K, Douglas RG.

Rhinology. 2017 Dec 1;55(4):291-297. doi: 10.4193/Rhin17.135. Review.

PMID:
28988258
10.

A potential role for staphylococcal and streptococcal superantigens in driving skewing of TCR Vβ subsets in tonsillar hyperplasia.

Radcliff FJ, Clow F, Mahadevan M, Johnston J, Proft T, Douglas RG, Fraser JD.

Med Microbiol Immunol. 2017 Aug;206(4):337-346. doi: 10.1007/s00430-017-0510-5. Epub 2017 May 4.

PMID:
28474248
11.

Effectiveness of extensive sinus surgery with post-operative medical management for chronic rhinosinusitis.

Wood AJ, Zhou L, Wilkinson S, Douglas RG.

J Laryngol Otol. 2017 Jul;131(S2):S19-S24. doi: 10.1017/S0022215116009361. Epub 2017 Feb 20.

PMID:
28215205
12.

Evaluating the Impact of DNA Extraction Method on the Representation of Human Oral Bacterial and Fungal Communities.

Vesty A, Biswas K, Taylor MW, Gear K, Douglas RG.

PLoS One. 2017 Jan 18;12(1):e0169877. doi: 10.1371/journal.pone.0169877. eCollection 2017.

13.

Toll-like receptor activation by sino-nasal mucus in chronic rhinosinusitis.

Biswas K, Chang A, Hoggard M, Radcliff FJ, Jiang Y, Taylor MW, Darveau R, Douglas RG.

Rhinology. 2017 Mar 1;55(1):59-69. doi: 10.4193/Rhin16.201.

PMID:
28025987
14.

The Dynamic Nonprime Binding of Sampatrilat to the C-Domain of Angiotensin-Converting Enzyme.

Sharma RK, Espinoza-Moraga M, Poblete H, Douglas RG, Sturrock ED, Caballero J, Chibale K.

J Chem Inf Model. 2016 Dec 27;56(12):2486-2494. doi: 10.1021/acs.jcim.6b00524. Epub 2016 Dec 13.

PMID:
27959521
15.

Chronic Rhinosinusitis and the Evolving Understanding of Microbial Ecology in Chronic Inflammatory Mucosal Disease.

Hoggard M, Wagner Mackenzie B, Jain R, Taylor MW, Biswas K, Douglas RG.

Clin Microbiol Rev. 2017 Jan;30(1):321-348. Review.

16.

Bacterial community collapse: a meta-analysis of the sinonasal microbiota in chronic rhinosinusitis.

Wagner Mackenzie B, Waite DW, Hoggard M, Douglas RG, Taylor MW, Biswas K.

Environ Microbiol. 2017 Jan;19(1):381-392. doi: 10.1111/1462-2920.13632. Epub 2017 Jan 18.

PMID:
27902866
17.

Evidence of microbiota dysbiosis in chronic rhinosinusitis.

Hoggard M, Biswas K, Zoing M, Wagner Mackenzie B, Taylor MW, Douglas RG.

Int Forum Allergy Rhinol. 2017 Mar;7(3):230-239. doi: 10.1002/alr.21871. Epub 2016 Nov 23.

PMID:
27879060
18.

Airflow in the Human Nasal Passage and Sinuses of Chronic Rhinosinusitis Subjects.

Kumar H, Jain R, Douglas RG, Tawhai MH.

PLoS One. 2016 Jun 1;11(6):e0156379. doi: 10.1371/journal.pone.0156379. eCollection 2016.

19.

A small mitochondrial protein present in myzozoans is essential for malaria transmission.

Klug D, Mair GR, Frischknecht F, Douglas RG.

Open Biol. 2016 Apr;6(4):160034. doi: 10.1098/rsob.160034.

20.

Kinetic and structural characterization of amyloid-β peptide hydrolysis by human angiotensin-1-converting enzyme.

Larmuth KM, Masuyer G, Douglas RG, Schwager SL, Acharya KR, Sturrock ED.

FEBS J. 2016 Mar;283(6):1060-76. doi: 10.1111/febs.13647. Epub 2016 Feb 9.

21.

Structural basis of Ac-SDKP hydrolysis by Angiotensin-I converting enzyme.

Masuyer G, Douglas RG, Sturrock ED, Acharya KR.

Sci Rep. 2015 Sep 25;5:13742. doi: 10.1038/srep13742.

22.

Paired analysis of the microbiota of surface mucus and whole-tissue specimens in patients with chronic rhinosinusitis.

Kim RJ, Biswas K, Hoggard M, Taylor MW, Douglas RG.

Int Forum Allergy Rhinol. 2015 Oct;5(10):877-83. doi: 10.1002/alr.21600. Epub 2015 Jul 28.

PMID:
26215930
23.

Active migration and passive transport of malaria parasites.

Douglas RG, Amino R, Sinnis P, Frischknecht F.

Trends Parasitol. 2015 Aug;31(8):357-62. doi: 10.1016/j.pt.2015.04.010. Epub 2015 May 20. Review.

PMID:
26001482
24.

The nasal microbiota in health and disease: variation within and between subjects.

Biswas K, Hoggard M, Jain R, Taylor MW, Douglas RG.

Front Microbiol. 2015 Mar 2;9:134. doi: 10.3389/fmicb.2015.00134. eCollection 2015.

25.

Chronic rhinosinusitis and cystic fibrosis: the interaction between sinus bacteria and mucosal immunity.

Kim RJ, Park L, Wood AJ, Yin T, Jain R, Douglas RG.

Int Forum Allergy Rhinol. 2015 May;5(5):380-5. doi: 10.1002/alr.21431. Epub 2015 Mar 16.

PMID:
25778791
26.

Imidazoline use in sinonasal surgery.

Campbell RG, Nair S, Sacks R, Douglas RG.

Med Hypotheses. 2014 Jun;82(6):706-8. doi: 10.1016/j.mehy.2014.03.009. Epub 2014 Mar 13.

PMID:
24690300
27.

A novel angiotensin I-converting enzyme mutation (S333W) impairs N-domain enzymatic cleavage of the anti-fibrotic peptide, AcSDKP.

Danilov SM, Wade MS, Schwager SL, Douglas RG, Nesterovitch AB, Popova IA, Hogarth KD, Bhardwaj N, Schwartz DE, Sturrock ED, Garcia JG.

PLoS One. 2014 Feb 4;9(2):e88001. doi: 10.1371/journal.pone.0088001. eCollection 2014.

28.

The interaction between bacteria and mucosal immunity in chronic rhinosinusitis: a prospective cross-sectional analysis.

Kim RJ, Yin T, Chen CJ, Mansell CJ, Wood A, Dunbar PR, Douglas RG.

Am J Rhinol Allergy. 2013 Nov-Dec;27(6):e183-9. doi: 10.2500/ajra.2013.27.3974.

PMID:
24274212
29.

The interaction between bacteria and mucosal immunity in chronic rhinosinusitis: A prospective cross-sectional analysis.

Kim RJT, Yin T, Chen CJ, Mansell CJ, Wood A, Dunbar PR, Douglas RG.

Am J Rhinol Allergy. 2013 Nov 1;27(6):183-189. doi: 10.2500/ajra.2013.27.3974.

PMID:
29021072
30.

Fragment-based design for the development of N-domain-selective angiotensin-1-converting enzyme inhibitors.

Douglas RG, Sharma RK, Masuyer G, Lubbe L, Zamora I, Acharya KR, Chibale K, Sturrock ED.

Clin Sci (Lond). 2014 Feb;126(4):305-13. doi: 10.1042/CS20130403.

31.

Fungal rhinosinusitis: what every allergist should know.

Callejas CA, Douglas RG.

Clin Exp Allergy. 2013 Aug;43(8):835-49. doi: 10.1111/cea.12118. Review.

PMID:
23889239
32.

Physical characteristics of commercial and home-made nasal lavage solutions.

Lilic N, Waldvogel-Thurlow S, Douglas RG.

J Laryngol Otol. 2014 Jan;128 Suppl 1:S40-3. doi: 10.1017/S0022215113001291. Epub 2013 Jun 11.

PMID:
23750714
33.

Characterization of angiotensin I-converting enzyme N-domain selectivity using positional-scanning combinatorial libraries of fluorescence resonance energy transfer peptides.

Bersanetti PA, Sabatini RA, Matos BS, Douglas RG, Nchinda A, Juliano MA, Pesquero JB, Sturrock ED, Carmona AK.

Biol Chem. 2012 Dec;393(12):1547-54.

PMID:
23667908
34.

Antifibrotic peptide N-acetyl-Ser-Asp-Lys-Pro (Ac-SDKP): opportunities for angiotensin-converting enzyme inhibitor design.

Douglas RG, Ehlers MR, Sturrock ED.

Clin Exp Pharmacol Physiol. 2013 Aug;40(8):535-41. doi: 10.1111/1440-1681.12062. Review.

PMID:
23351021
35.

Silastic splints reduce middle meatal adhesions after endoscopic sinus surgery.

Baguley CJ, Stow NW, Weitzel EK, Douglas RG.

Am J Rhinol Allergy. 2012 Sep-Oct;26(5):414-7. doi: 10.2500/ajra.2012.26.3810.

PMID:
23168159
36.

Efficacy of medical therapy in treatment of chronic rhinosinusitis.

Young LC, Stow NW, Zhou L, Douglas RG.

Allergy Rhinol (Providence). 2012;3(1):e8-e12. doi: 10.2500/ar.2012.3.0027. Epub 2012 May 18.

37.

Intramucosal bacterial microcolonies exist in chronic rhinosinusitis without inducing a local immune response.

Wood AJ, Fraser JD, Swift S, Patterson-Emanuelson EA, Amirapu S, Douglas RG.

Am J Rhinol Allergy. 2012 Jul-Aug;26(4):265-70. doi: 10.2500/ajra.2012.26.3779.

PMID:
22801011
38.

Staphylococcus aureus. Letters to the editor.

Wood AJ, Fraser JD, Amirapu S, Douglas RG.

Am J Rhinol Allergy. 2012 May-Jun;26(3):249-50; author reply 250. doi: 10.2500/ajra.2012.26.3775. No abstract available.

PMID:
22643955
39.

New ketomethylene inhibitor analogues: synthesis and assessment of structural determinants for N-domain selective inhibition of angiotensin-converting enzyme.

Sharma RK, Douglas RG, Louw S, Chibale K, Sturrock ED.

Biol Chem. 2012 May;393(6):485-93. doi: 10.1515/hsz-2012-0127.

PMID:
22628311
40.

Are biofilms associated with an inflammatory response in chronic rhinosinusitis?

Wood AJ, Fraser J, Swift S, Amirapu S, Douglas RG.

Int Forum Allergy Rhinol. 2011 Sep-Oct;1(5):335-9. doi: 10.1002/alr.20060. Epub 2011 Jun 6.

PMID:
22287462
41.

Is chronic rhinosinusitis caused by persistent respiratory virus infection?

Wood AJ, Antoszewska H, Fraser J, Douglas RG.

Int Forum Allergy Rhinol. 2011 Mar-Apr;1(2):95-100. doi: 10.1002/alr.20030. Epub 2011 Mar 16.

PMID:
22287325
42.

Bacterial microcolonies exist within the sphenoid bone in chronic rhinosinusitis and healthy controls.

Wood AJ, Fraser J, Amirapu S, Douglas RG.

Int Forum Allergy Rhinol. 2012 Mar-Apr;2(2):116-21. doi: 10.1002/alr.21010. Epub 2012 Jan 17.

PMID:
22253188
43.

Pathogenesis and treatment of chronic rhinosinusitis.

Wood AJ, Douglas RG.

Postgrad Med J. 2010 Jun;86(1016):359-64. doi: 10.1136/pgmj.2009.094813. Review. Erratum in: Postgrad Med J. 2010 Aug;86(1018):512.

PMID:
20547603
44.

Investigating the domain specificity of phosphinic inhibitors RXPA380 and RXP407 in angiotensin-converting enzyme.

Kröger WL, Douglas RG, O'Neill HG, Dive V, Sturrock ED.

Biochemistry. 2009 Sep 8;48(35):8405-12. doi: 10.1021/bi9011226.

PMID:
19658433
45.

The prevalence of atopic symptoms in children with otitis media with effusion.

Souter MA, Mills NA, Mahadevan M, Douglas G, Ellwood PE, Asher MI, Clayton TO, Douglas RG.

Otolaryngol Head Neck Surg. 2009 Jul;141(1):104-7. doi: 10.1016/j.otohns.2009.03.007.

PMID:
19559967
46.

Immunizations in the United States: success, structure, and stress.

Orenstein WA, Douglas RG, Rodewald LE, Hinman AR.

Health Aff (Millwood). 2005 May-Jun;24(3):599-610.

PMID:
15886150
47.

Medicine. The need for a global HIV vaccine enterprise.

Klausner RD, Fauci AS, Corey L, Nabel GJ, Gayle H, Berkley S, Haynes BF, Baltimore D, Collins C, Douglas RG, Esparza J, Francis DP, Ganguly NK, Gerberding JL, Johnston MI, Kazatchkine MD, McMichael AJ, Makgoba MW, Pantaleo G, Piot P, Shao Y, Tramont E, Varmus H, Wasserheit JN.

Science. 2003 Jun 27;300(5628):2036-9.

PMID:
12829768
48.

Tuberculosis: the beginning of the end?

Douglas RG, Douglas AC.

Trans Am Clin Climatol Assoc. 2001;112:1-13. No abstract available.

49.

Will a new vaccine be used?

Douglas RG.

J Hum Virol. 2000 Mar-Apr;3(2):77-80.

PMID:
10850892
50.

Phytophotodermatitis in pigs exposed to parsley (Petroselinum crispum).

Griffiths IB, Douglas RG.

Vet Rec. 2000 Jan 15;146(3):73-4. No abstract available.

PMID:
10674694

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