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Items: 30

1.

Candidate biomarkers of PARP inhibitor sensitivity in ovarian cancer beyond the BRCA genes.

Hodgson DR, Dougherty BA, Lai Z, Fielding A, Grinsted L, Spencer S, O'Connor MJ, Ho TW, Robertson JD, Lanchbury JS, Timms KM, Gutin A, Orr M, Jones H, Gilks B, Womack C, Gourley C, Ledermann J, Barrett JC.

Br J Cancer. 2018 Nov;119(11):1401-1409. doi: 10.1038/s41416-018-0274-8. Epub 2018 Oct 24.

PMID:
30353044
2.

Generation of stable PDX derived cell lines using conditional reprogramming.

Borodovsky A, McQuiston TJ, Stetson D, Ahmed A, Whitston D, Zhang J, Grondine M, Lawson D, Challberg SS, Zinda M, Pollok BA, Dougherty BA, D'Cruz CM.

Mol Cancer. 2017 Dec 6;16(1):177. doi: 10.1186/s12943-017-0745-1.

3.

Biological and clinical evidence for somatic mutations in BRCA1 and BRCA2 as predictive markers for olaparib response in high-grade serous ovarian cancers in the maintenance setting.

Dougherty BA, Lai Z, Hodgson DR, Orr MCM, Hawryluk M, Sun J, Yelensky R, Spencer SK, Robertson JD, Ho TW, Fielding A, Ledermann JA, Barrett JC.

Oncotarget. 2017 Jul 4;8(27):43653-43661. doi: 10.18632/oncotarget.17613.

4.

Long-Term Responders on Olaparib Maintenance in High-Grade Serous Ovarian Cancer: Clinical and Molecular Characterization.

Lheureux S, Lai Z, Dougherty BA, Runswick S, Hodgson DR, Timms KM, Lanchbury JS, Kaye S, Gourley C, Bowtell D, Kohn EC, Scott C, Matulonis U, Panzarella T, Karakasis K, Burnier JV, Gilks CB, O'Connor MJ, Robertson JD, Ledermann J, Barrett JC, Ho TW, Oza AM.

Clin Cancer Res. 2017 Aug 1;23(15):4086-4094. doi: 10.1158/1078-0432.CCR-16-2615. Epub 2017 Feb 21.

5.

Genetic organization of transposase regions surrounding blaKPC carbapenemase genes on plasmids from Klebsiella strains isolated in a New York City hospital.

Gootz TD, Lescoe MK, Dib-Hajj F, Dougherty BA, He W, Della-Latta P, Huard RC.

Antimicrob Agents Chemother. 2009 May;53(5):1998-2004. doi: 10.1128/AAC.01355-08. Epub 2009 Mar 2.

6.

Conserved fungal genes as potential targets for broad-spectrum antifungal drug discovery.

Liu M, Healy MD, Dougherty BA, Esposito KM, Maurice TC, Mazzucco CE, Bruccoleri RE, Davison DB, Frosco M, Barrett JF, Wang YK.

Eukaryot Cell. 2006 Apr;5(4):638-49.

7.

Structural and functional characterization of CFE88: evidence that a conserved and essential bacterial protein is a methyltransferase.

Constantine KL, Krystek SR, Healy MD, Doyle ML, Siemers NO, Thanassi J, Yan N, Xie D, Goldfarb V, Yanchunas J, Tao L, Dougherty BA, Farmer BT 2nd.

Protein Sci. 2005 Jun;14(6):1472-84.

8.

Purification, cloning, and functional expression of phenylalanine aminomutase: the first committed step in Taxol side-chain biosynthesis.

Steele CL, Chen Y, Dougherty BA, Li W, Hofstead S, Lam KS, Xing Z, Chiang SJ.

Arch Biochem Biophys. 2005 Jun 1;438(1):1-10.

PMID:
15878763
9.

Decrypting the biochemical function of an essential gene from Streptococcus pneumoniae using ThermoFluor technology.

Carver TE, Bordeau B, Cummings MD, Petrella EC, Pucci MJ, Zawadzke LE, Dougherty BA, Tredup JA, Bryson JW, Yanchunas J Jr, Doyle ML, Witmer MR, Nelen MI, DesJarlais RL, Jaeger EP, Devine H, Asel ED, Springer BA, Bone R, Salemme FR, Todd MJ.

J Biol Chem. 2005 Mar 25;280(12):11704-12. Epub 2005 Jan 5.

10.

Role of mobile DNA in the evolution of vancomycin-resistant Enterococcus faecalis.

Paulsen IT, Banerjei L, Myers GS, Nelson KE, Seshadri R, Read TD, Fouts DE, Eisen JA, Gill SR, Heidelberg JF, Tettelin H, Dodson RJ, Umayam L, Brinkac L, Beanan M, Daugherty S, DeBoy RT, Durkin S, Kolonay J, Madupu R, Nelson W, Vamathevan J, Tran B, Upton J, Hansen T, Shetty J, Khouri H, Utterback T, Radune D, Ketchum KA, Dougherty BA, Fraser CM.

Science. 2003 Mar 28;299(5615):2071-4.

11.

Identification of 113 conserved essential genes using a high-throughput gene disruption system in Streptococcus pneumoniae.

Thanassi JA, Hartman-Neumann SL, Dougherty TJ, Dougherty BA, Pucci MJ.

Nucleic Acids Res. 2002 Jul 15;30(14):3152-62.

12.

Efflux in bacteria: what do we really know about it?

Ryan BM, Dougherty TJ, Beaulieu D, Chuang J, Dougherty BA, Barrett JF.

Expert Opin Investig Drugs. 2001 Aug;10(8):1409-22. Review.

PMID:
11772259
13.

Random chromosomal gene disruption using cassette mutagenesis.

Lewis FA 3rd, Dougherty BA.

Methods Mol Biol. 2002;182:173-87. No abstract available.

PMID:
11768964
14.

Finding drug targets in microbial genomes.

Read TD, Gill SR, Tettelin H, Dougherty BA.

Drug Discov Today. 2001 Sep 1;6(17):887-892.

PMID:
11522517
15.

Complete genome sequence of a virulent isolate of Streptococcus pneumoniae.

Tettelin H, Nelson KE, Paulsen IT, Eisen JA, Read TD, Peterson S, Heidelberg J, DeBoy RT, Haft DH, Dodson RJ, Durkin AS, Gwinn M, Kolonay JF, Nelson WC, Peterson JD, Umayam LA, White O, Salzberg SL, Lewis MR, Radune D, Holtzapple E, Khouri H, Wolf AM, Utterback TR, Hansen CL, McDonald LA, Feldblyum TV, Angiuoli S, Dickinson T, Hickey EK, Holt IE, Loftus BJ, Yang F, Smith HO, Venter JC, Dougherty BA, Morrison DA, Hollingshead SK, Fraser CM.

Science. 2001 Jul 20;293(5529):498-506.

16.

Complete genome sequence of Neisseria meningitidis serogroup B strain MC58.

Tettelin H, Saunders NJ, Heidelberg J, Jeffries AC, Nelson KE, Eisen JA, Ketchum KA, Hood DW, Peden JF, Dodson RJ, Nelson WC, Gwinn ML, DeBoy R, Peterson JD, Hickey EK, Haft DH, Salzberg SL, White O, Fleischmann RD, Dougherty BA, Mason T, Ciecko A, Parksey DS, Blair E, Cittone H, Clark EB, Cotton MD, Utterback TR, Khouri H, Qin H, Vamathevan J, Gill J, Scarlato V, Masignani V, Pizza M, Grandi G, Sun L, Smith HO, Fraser CM, Moxon ER, Rappuoli R, Venter JC.

Science. 2000 Mar 10;287(5459):1809-15.

18.

Identification of Haemophilus influenzae Rd transformation genes using cassette mutagenesis.

Dougherty BA, Smith HO.

Microbiology. 1999 Feb;145 ( Pt 2):401-9.

PMID:
10075422
19.

Sequence and analysis of the 60 kb conjugative, bacteriocin-producing plasmid pMRC01 from Lactococcus lactis DPC3147.

Dougherty BA, Hill C, Weidman JF, Richardson DR, Venter JC, Ross RP.

Mol Microbiol. 1998 Aug;29(4):1029-38.

20.

The complete genome sequence of the hyperthermophilic, sulphate-reducing archaeon Archaeoglobus fulgidus.

Klenk HP, Clayton RA, Tomb JF, White O, Nelson KE, Ketchum KA, Dodson RJ, Gwinn M, Hickey EK, Peterson JD, Richardson DL, Kerlavage AR, Graham DE, Kyrpides NC, Fleischmann RD, Quackenbush J, Lee NH, Sutton GG, Gill S, Kirkness EF, Dougherty BA, McKenney K, Adams MD, Loftus B, Peterson S, Reich CI, McNeil LK, Badger JH, Glodek A, Zhou L, Overbeek R, Gocayne JD, Weidman JF, McDonald L, Utterback T, Cotton MD, Spriggs T, Artiach P, Kaine BP, Sykes SM, Sadow PW, D'Andrea KP, Bowman C, Fujii C, Garland SA, Mason TM, Olsen GJ, Fraser CM, Smith HO, Woese CR, Venter JC.

Nature. 1997 Nov 27;390(6658):364-70. Erratum in: Nature 1998 Jul 2;394(6688):101.

PMID:
9389475
21.

The complete genome sequence of the gastric pathogen Helicobacter pylori.

Tomb JF, White O, Kerlavage AR, Clayton RA, Sutton GG, Fleischmann RD, Ketchum KA, Klenk HP, Gill S, Dougherty BA, Nelson K, Quackenbush J, Zhou L, Kirkness EF, Peterson S, Loftus B, Richardson D, Dodson R, Khalak HG, Glodek A, McKenney K, Fitzegerald LM, Lee N, Adams MD, Hickey EK, Berg DE, Gocayne JD, Utterback TR, Peterson JD, Kelley JM, Cotton MD, Weidman JM, Fujii C, Bowman C, Watthey L, Wallin E, Hayes WS, Borodovsky M, Karp PD, Smith HO, Fraser CM, Venter JC.

Nature. 1997 Aug 7;388(6642):539-47. Erratum in: Nature 1997 Sep 25;389(6649):412.

PMID:
9252185
22.

Tn916 transposition in Haemophilus influenzae Rd: preferential insertion into noncoding DNA.

Nelson KE, Richardson DL, Dougherty BA.

Microb Comp Genomics. 1997;2(4):313-21.

PMID:
9689229
23.

Complete genome sequence of the methanogenic archaeon, Methanococcus jannaschii.

Bult CJ, White O, Olsen GJ, Zhou L, Fleischmann RD, Sutton GG, Blake JA, FitzGerald LM, Clayton RA, Gocayne JD, Kerlavage AR, Dougherty BA, Tomb JF, Adams MD, Reich CI, Overbeek R, Kirkness EF, Weinstock KG, Merrick JM, Glodek A, Scott JL, Geoghagen NS, Venter JC.

Science. 1996 Aug 23;273(5278):1058-73.

PMID:
8688087
25.

The minimal gene complement of Mycoplasma genitalium.

Fraser CM, Gocayne JD, White O, Adams MD, Clayton RA, Fleischmann RD, Bult CJ, Kerlavage AR, Sutton G, Kelley JM, Fritchman RD, Weidman JF, Small KV, Sandusky M, Fuhrmann J, Nguyen D, Utterback TR, Saudek DM, Phillips CA, Merrick JM, Tomb JF, Dougherty BA, Bott KF, Hu PC, Lucier TS, Peterson SN, Smith HO, Hutchison CA 3rd, Venter JC.

Science. 1995 Oct 20;270(5235):397-403.

PMID:
7569993
26.

Frequency and distribution of DNA uptake signal sequences in the Haemophilus influenzae Rd genome.

Smith HO, Tomb JF, Dougherty BA, Fleischmann RD, Venter JC.

Science. 1995 Jul 28;269(5223):538-40.

PMID:
7542802
27.

Whole-genome random sequencing and assembly of Haemophilus influenzae Rd.

Fleischmann RD, Adams MD, White O, Clayton RA, Kirkness EF, Kerlavage AR, Bult CJ, Tomb JF, Dougherty BA, Merrick JM, et al.

Science. 1995 Jul 28;269(5223):496-512.

PMID:
7542800
28.
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