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Items: 1 to 20 of 640

1.

FAMIN Is a Multifunctional Purine Enzyme Enabling the Purine Nucleotide Cycle.

Cader MZ, de Almeida Rodrigues RP, West JA, Sewell GW, Md-Ibrahim MN, Reikine S, Sirago G, Unger LW, Inglesias-Romero AB, Ramshorn K, Haag LM, Saveljeva S, Ebel JF, Rosenstiel P, Kaneider NC, Lee JC, Lawley TD, Bradley A, Dougan G, Modis Y, Griffin JL, Kaser A.

Cell. 2020 Jan 23;180(2):278-295.e23. doi: 10.1016/j.cell.2019.12.017.

PMID:
31978345
2.

Genetic variation associated with infection and the environment in the accidental pathogen Burkholderia pseudomallei.

Chewapreecha C, Mather AE, Harris SR, Hunt M, Holden MTG, Chaichana C, Wuthiekanun V, Dougan G, Day NPJ, Limmathurotsakul D, Parkhill J, Peacock SJ.

Commun Biol. 2019 Nov 22;2(1):428. doi: 10.1038/s42003-019-0678-x.

PMID:
31925232
3.

SLAMF9 is found on select subsets of antigen-presenting cells and promotes resistance to Salmonella infection.

Wilson TJ, Clare S, Mikulin J, Johnson CM, Harcourt K, Lyons PA, Dougan G, Smith KGC.

Immunology. 2019 Dec 27. doi: 10.1111/imm.13169. [Epub ahead of print]

PMID:
31880316
4.

High-throughput phenotyping reveals expansive genetic and structural underpinnings of immune variation.

Abeler-Dörner L, Laing AG, Lorenc A, Ushakov DS, Clare S, Speak AO, Duque-Correa MA, White JK, Ramirez-Solis R, Saran N, Bull KR, Morón B, Iwasaki J, Barton PR, Caetano S, Hng KI, Cambridge E, Forman S, Crockford TL, Griffiths M, Kane L, Harcourt K, Brandt C, Notley G, Babalola KO, Warren J, Mason JC, Meeniga A, Karp NA, Melvin D, Cawthorne E, Weinrick B, Rahim A, Drissler S, Meskas J, Yue A, Lux M, Song-Zhao GX, Chan A, Ballesteros Reviriego C, Abeler J, Wilson H, Przemska-Kosicka A, Edmans M, Strevens N, Pasztorek M, Meehan TF, Powrie F, Brinkman R, Dougan G, Jacobs W Jr, Lloyd CM, Cornall RJ, Maloy KJ, Grencis RK, Griffiths GM, Adams DJ, Hayday AC.

Nat Immunol. 2020 Jan;21(1):86-100. doi: 10.1038/s41590-019-0549-0. Epub 2019 Dec 16.

PMID:
31844327
5.

Loss of IL-10 signaling in macrophages limits bacterial killing driven by prostaglandin E2.

Mukhopadhyay S, Heinz E, Porreca I, Alasoo K, Yeung A, Yang HT, Schwerd T, Forbester JL, Hale C, Agu CA, Choi YH, Rodrigues J, Capitani M, Jostins-Dean L, Thomas DC, Travis S, Gaffney D, Skarnes WC, Thomson N, Uhlig HH, Dougan G, Powrie F.

J Exp Med. 2020 Feb 3;217(2). pii: e20180649. doi: 10.1084/jem.20180649.

PMID:
31819956
6.

Genetic variation associated with infection and the environment in the accidental pathogen Burkholderia pseudomallei.

Chewapreecha C, Mather AE, Harris SR, Hunt M, Holden MTG, Chaichana C, Wuthiekanun V, Dougan G, Day NPJ, Limmathurotsakul D, Parkhill J, Peacock SJ.

Commun Biol. 2019 Nov 22;2:428. doi: 10.1038/s42003-019-0678-x. eCollection 2019.

7.

How Can the Typhoid Fever Surveillance in Africa and the Severe Typhoid Fever in Africa Programs Contribute to the Introduction of Typhoid Conjugate Vaccines?

Jeon HJ, Im J, Haselbeck A, Holm M, Rakotozandrindrainy R, Bassiahi AS, Panzner U, Mogeni OD, Seo HJ, Lunguya O, Jacobs J, Okeke IN, Terferi M, Owusu-Dabo E, Dougan G, Carey M, Steele AD, Kim JH, Clemens JD, Andrews JR, Park SE, Baker S, Marks F.

Clin Infect Dis. 2019 Oct 30;69(Supplement_6):S417-S421. doi: 10.1093/cid/ciz629.

8.

Persistent circulation of a fluoroquinolone-resistant Salmonella enterica Typhi clone in the Indian subcontinent.

Britto CD, Dyson ZA, Mathias S, Bosco A, Dougan G, Jose S, Nagaraj S, Holt KE, Pollard AJ.

J Antimicrob Chemother. 2020 Feb 1;75(2):337-341. doi: 10.1093/jac/dkz435.

PMID:
31665304
9.

An iPSC-Derived Myeloid Lineage Model of Herpes Virus Latency and Reactivation.

Poole E, Huang CJZ, Forbester J, Shnayder M, Nachshon A, Kweider B, Basaj A, Smith D, Jackson SE, Liu B, Shih J, Kiskin FN, Roche K, Murphy E, Wills MR, Morrell NW, Dougan G, Stern-Ginossar N, Rana AA, Sinclair J.

Front Microbiol. 2019 Oct 9;10:2233. doi: 10.3389/fmicb.2019.02233. eCollection 2019.

10.

A Biohistorical Perspective of Typhoid and Antimicrobial Resistance.

Kirchhelle C, Dyson ZA, Dougan G.

Clin Infect Dis. 2019 Oct 15;69(Supplement_5):S388-S394. doi: 10.1093/cid/ciz556.

11.

A Genome-Wide Knockout Screen in Human Macrophages Identified Host Factors Modulating Salmonella Infection.

Yeung ATY, Choi YH, Lee AHY, Hale C, Ponstingl H, Pickard D, Goulding D, Thomas M, Gill E, Kim JK, Bradley A, Hancock REW, Dougan G.

mBio. 2019 Oct 8;10(5). pii: e02169-19. doi: 10.1128/mBio.02169-19.

12.

The flagellotropic bacteriophage YSD1 targets Salmonella Typhi with a Chi-like protein tail fibre.

Dunstan RA, Pickard D, Dougan S, Goulding D, Cormie C, Hardy J, Li F, Grinter R, Harcourt K, Yu L, Song J, Schreiber F, Choudhary J, Clare S, Coulibaly F, Strugnell RA, Dougan G, Lithgow T.

Mol Microbiol. 2019 Dec;112(6):1831-1846. doi: 10.1111/mmi.14396. Epub 2019 Oct 9.

PMID:
31556164
13.
14.

An African Salmonella Typhimurium ST313 sublineage with extensive drug-resistance and signatures of host adaptation.

Van Puyvelde S, Pickard D, Vandelannoote K, Heinz E, Barbé B, de Block T, Clare S, Coomber EL, Harcourt K, Sridhar S, Lees EA, Wheeler NE, Klemm EJ, Kuijpers L, Mbuyi Kalonji L, Phoba MF, Falay D, Ngbonda D, Lunguya O, Jacobs J, Dougan G, Deborggraeve S.

Nat Commun. 2019 Sep 19;10(1):4280. doi: 10.1038/s41467-019-11844-z.

15.

Emergence of NDM-producing Klebsiella pneumoniae and Escherichia coli in Spain: phylogeny, resistome, virulence and plasmids encoding blaNDM-like genes as determined by WGS.

Pérez-Vázquez M, Sola Campoy PJ, Ortega A, Bautista V, Monzón S, Ruiz-Carrascoso G, Mingorance J, González-Barberá EM, Gimeno C, Aracil B, Sáez D, Lara N, Fernández S, González-López JJ, Campos J, Kingsley RA, Dougan G, Oteo-Iglesias J; Spanish NDM Study Group .

J Antimicrob Chemother. 2019 Dec 1;74(12):3489-3496. doi: 10.1093/jac/dkz366.

PMID:
31504589
16.

Contrasting patterns of longitudinal population dynamics and antimicrobial resistance mechanisms in two priority bacterial pathogens over 7 years in a single center.

Ellington MJ, Heinz E, Wailan AM, Dorman MJ, de Goffau M, Cain AK, Henson SP, Gleadall N, Boinett CJ, Dougan G, Brown NM, Woodford N, Parkhill J, Török ME, Peacock SJ, Thomson NR.

Genome Biol. 2019 Sep 2;20(1):184. doi: 10.1186/s13059-019-1785-1.

17.

Diagnostic host gene signature for distinguishing enteric fever from other febrile diseases.

Blohmke CJ, Muller J, Gibani MM, Dobinson H, Shrestha S, Perinparajah S, Jin C, Hughes H, Blackwell L, Dongol S, Karkey A, Schreiber F, Pickard D, Basnyat B, Dougan G, Baker S, Pollard AJ, Darton TC.

EMBO Mol Med. 2019 Oct;11(10):e10431. doi: 10.15252/emmm.201910431. Epub 2019 Aug 30.

18.

Adaptation of host transmission cycle during Clostridium difficile speciation.

Kumar N, Browne HP, Viciani E, Forster SC, Clare S, Harcourt K, Stares MD, Dougan G, Fairley DJ, Roberts P, Pirmohamed M, Clokie MRJ, Jensen MBF, Hargreaves KR, Ip M, Wieler LH, Seyboldt C, Norén T, Riley TV, Kuijper EJ, Wren BW, Lawley TD.

Nat Genet. 2019 Sep;51(9):1315-1320. doi: 10.1038/s41588-019-0478-8. Epub 2019 Aug 12.

PMID:
31406348
19.

Corrigendum: Five decades of genome evolution in the globally distributed, extensively antibiotic-resistant Acinetobacter baumannii global clone 1.

Holt KE, Kenyon JJ, Hamidian M, Schultz MB, Pickard DJ, Dougan G, Hall RM.

Microb Genom. 2019 Jul;5(7). doi: 10.1099/mgen.0.000280. No abstract available.

20.

Molecular epidemiology and intercontinental spread of cholera.

Mutreja A, Dougan G.

Vaccine. 2019 Jul 22. pii: S0264-410X(19)30929-6. doi: 10.1016/j.vaccine.2019.07.038. [Epub ahead of print]

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